Published in J Immunol on July 08, 2009
The lymphatic vasculature in disease. Nat Med (2011) 4.20
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes. Nat Immunol (2011) 2.38
Current views on the function of the lymphatic vasculature in health and disease. Genes Dev (2010) 1.84
Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat Rev Cancer (2012) 1.78
Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. J Exp Med (2013) 1.77
An important role of lymphatic vessel activation in limiting acute inflammation. Blood (2011) 1.62
Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity. Immunol Rev (2013) 1.40
Emerging roles of lymphatic endothelium in regulating adaptive immunity. J Clin Invest (2014) 1.09
Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance. J Exp Med (2014) 1.08
The cutaneous vascular system in chronic skin inflammation. J Investig Dermatol Symp Proc (2011) 1.06
A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis. J Biol Chem (2011) 1.02
The new era of the lymphatic system: no longer secondary to the blood vascular system. Cold Spring Harb Perspect Med (2012) 0.97
Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells. J Immunol (2014) 0.97
Lymphatic endothelial cells - key players in regulation of tolerance and immunity. Front Immunol (2012) 0.94
Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection. J Clin Invest (2015) 0.94
The lymph node microenvironment and its role in the progression of metastatic cancer. Semin Cell Dev Biol (2015) 0.91
A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes. EMBO J (2013) 0.91
Myeloid cells and lymphangiogenesis. Cold Spring Harb Perspect Med (2012) 0.88
Lymphatic endothelial murine chloride channel calcium-activated 1 is a ligand for leukocyte LFA-1 and Mac-1. J Immunol (2010) 0.86
Modes of Antigen Presentation by Lymph Node Stromal Cells and Their Immunological Implications. Front Immunol (2015) 0.83
Tolerance and lymphoid organ structure and function. Front Immunol (2011) 0.83
Lymphatic system: an active pathway for immune protection. Semin Cell Dev Biol (2014) 0.83
Role of lymphatic vasculature in regional and distant metastases. Microvasc Res (2014) 0.83
Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes. Front Immunol (2013) 0.83
Lymphatic vessels regulate immune microenvironments in human and murine melanoma. J Clin Invest (2016) 0.82
Lymphangiogenesis is induced by mycobacterial granulomas via vascular endothelial growth factor receptor-3 and supports systemic T-cell responses against mycobacterial antigen. Am J Pathol (2015) 0.82
The role of non-hematopoietic stromal cells in the persistence of inflammation. Front Immunol (2013) 0.82
Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer. Cancer Discov (2015) 0.81
Lipopolysaccharide modulates neutrophil recruitment and macrophage polarization on lymphatic vessels and impairs lymphatic function in rat mesentery. Am J Physiol Heart Circ Physiol (2015) 0.81
Growth differentiation factor-15 suppresses maturation and function of dendritic cells and inhibits tumor-specific immune response. PLoS One (2013) 0.81
Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease? Neuron (2016) 0.81
Heterogeneity in the lymphatic vascular system and its origin. Cardiovasc Res (2016) 0.81
The Lymphatic System in Disease Processes and Cancer Progression. Annu Rev Biomed Eng (2016) 0.80
Regulation of T-cell Tolerance by Lymphatic Endothelial Cells. J Clin Cell Immunol (2014) 0.79
MicroRNA signature of inflamed lymphatic endothelium and role of miR-9 in lymphangiogenesis and inflammation. Am J Physiol Cell Physiol (2015) 0.79
A VEGFR-3 antagonist increases IFN-γ expression on low functioning NK cells in acute myeloid leukemia. J Clin Immunol (2013) 0.79
Galectin-1 regulates tissue exit of specific dendritic cell populations. J Biol Chem (2015) 0.79
Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation. Oncotarget (2016) 0.78
Lymphatic filariasis: perspectives on lymphatic remodeling and contractile dysfunction in filarial disease pathogenesis. Microcirculation (2013) 0.78
Role of dendritic cells in cardiovascular diseases. World J Cardiol (2010) 0.78
Dendritic cell interactions with lymphatic endothelium. Lymphat Res Biol (2013) 0.78
(Lymph)angiogenic influences on hematopoietic cells in acute myeloid leukemia. Exp Mol Med (2014) 0.78
Lymphatic Regulation of Cellular Trafficking. J Clin Cell Immunol (2014) 0.78
Melanoma exosomes enable tumor tolerance in lymph nodes. Med Hypotheses (2016) 0.77
Promoting inflammatory lymphangiogenesis by vascular endothelial growth factor-C (VEGF-C) aggravated intestinal inflammation in mice with experimental acute colitis. Braz J Med Biol Res (2016) 0.76
The lymphatic system and pancreatic cancer. Cancer Lett (2015) 0.76
Lymph Nodes and Cancer Metastasis: New Perspectives on the Role of Intranodal Lymphatic Sinuses. Int J Mol Sci (2016) 0.75
Emerging Roles of Lymphatic Vasculature in Immunity. Immune Netw (2017) 0.75
The Role of Lymphatic Endothelial Cells in Liver Injury and Tumor Development. Front Immunol (2016) 0.75
microRNAs in the Lymphatic Endothelium: Master Regulators of Lineage Plasticity and Inflammation. Front Immunol (2017) 0.75
Human Melanoma-Derived Extracellular Vesicles Regulate Dendritic Cell Maturation. Front Immunol (2017) 0.75
A robust in vitro model for trans-lymphatic endothelial migration. Sci Rep (2017) 0.75
LFA-1/ICAM-1 Interaction as a Therapeutic Target in Dry Eye Disease. J Ocul Pharmacol Ther (2016) 0.75
Bidirectional Crosstalk between Lymphatic Endothelial Cell and T Cell and Its Implications in Tumor Immunity. Front Immunol (2017) 0.75
Shaping of Peripheral T Cell Responses by Lymphatic Endothelial Cells. Front Immunol (2017) 0.75
T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo. J Immunol (2015) 0.75
The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment. Front Immunol (2016) 0.75
Tolerogenic dendritic cells. Annu Rev Immunol (2001) 13.77
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med (2001) 9.70
The many faces of macrophage activation. J Leukoc Biol (2003) 8.95
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med (2001) 7.78
Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc Natl Acad Sci U S A (1982) 7.16
Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci U S A (2002) 6.19
Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med (1996) 6.11
The induction of tolerance by dendritic cells that have captured apoptotic cells. J Exp Med (2000) 5.74
Characterization of nonlymphoid cells derived from rat peripheral lymph. J Exp Med (1983) 5.63
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest (2004) 5.59
Naive and memory T cells show distinct pathways of lymphocyte recirculation. J Exp Med (1990) 5.54
Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity (1999) 5.23
Induction of tolerance by IL-10-treated dendritic cells. J Immunol (1997) 4.65
Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol (2002) 4.64
Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat Rev Immunol (2005) 4.59
Regulation of T cell immunity by dendritic cells. Cell (2001) 4.38
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat Immunol (2005) 4.22
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest (2005) 4.09
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity (2006) 4.04
Conformational regulation of integrin structure and function. Annu Rev Biophys Biomol Struct (2001) 3.74
Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity (2007) 3.58
Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. J Exp Med (1994) 3.32
A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J Cell Biol (1993) 3.14
Cytokine regulation of endothelial cell function. FASEB J (1992) 3.00
The chemokine receptor D6 limits the inflammatory response in vivo. Nat Immunol (2005) 2.98
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J Cell Biol (1993) 2.87
The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. Cell (2000) 2.76
Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes. J Immunol (1991) 2.69
Molecular characterization of lymphatic endothelial cells. Proc Natl Acad Sci U S A (2002) 2.68
Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants. Nat Med (2006) 2.56
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets. J Immunol (1993) 2.55
The traffic of cells through tissues: a study of peripheral lymph in sheep. J Anat (1970) 2.24
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. Gastroenterology (2004) 2.02
An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J Exp Med (2006) 2.00
Dendritic cells as sensors of infection. Immunity (2001) 2.00
Therapeutic lymphangiogenesis with human recombinant VEGF-C. FASEB J (2002) 1.67
CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells. Immunity (2005) 1.63
Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin. J Exp Med (2002) 1.61
Regional differences in constitutive and induced ICAM-1 expression in vivo. Am J Physiol (1995) 1.42
Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat Med (2003) 1.38
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood (2006) 1.37
Lymphatic endothelium: morphological, molecular and functional properties. J Cell Biol (2003) 1.31
Ligation of E-cadherin on in vitro-generated immature Langerhans-type dendritic cells inhibits their maturation. Blood (2000) 1.28
Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation. Blood (2006) 1.23
Novel immunosuppressive properties of interleukin-6 in dendritic cells: inhibition of NF-kappaB binding activity and CCR7 expression. FASEB J (2004) 1.23
AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes. Proc Natl Acad Sci U S A (2006) 1.20
Inflammation, lymphatic function, and dendritic cell migration. Lymphat Res Biol (2006) 1.19
Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells. J Clin Invest (2002) 1.18
Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid. Proc Natl Acad Sci U S A (2007) 1.18
ICAM-1: targeted docking for exogenous as well as endogenous ligands. Adv Drug Deliv Rev (2004) 1.14
Complement receptor 3 ligation of dendritic cells suppresses their stimulatory capacity. J Immunol (2007) 1.05
Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules. J Leukoc Biol (1998) 1.05
IL-10 alters DC function via modulation of cell surface molecules resulting in impaired T-cell responses. Cell Immunol (2002) 1.04
The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur J Immunol (2001) 1.02
Modulation of dendritic cell phenotype and function in an in vitro model of the intestinal epithelium. Eur J Immunol (2006) 1.02
Dermal fibroblasts induce maturation of dendritic cells. J Immunol (2007) 1.00
Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1. J Leukoc Biol (2006) 0.98
In vivo treatment with anti-ICAM-1 and anti-LFA-1 antibodies inhibits contact sensitization-induced migration of epidermal Langerhans cells to regional lymph nodes. Cell Immunol (1994) 0.92
Impact of bronchial epithelium on dendritic cell migration and function: modulation by the bacterial motif KpOmpA. J Immunol (2006) 0.88
The innate reaction of the human skin lymphatic system to foreign and self-antigens. Lymphat Res Biol (2005) 0.85
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09
Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med (2004) 7.93
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 7.32
Nomenclature of monocytes and dendritic cells in blood. Blood (2010) 6.63
In vivo analysis of dendritic cell development and homeostasis. Science (2009) 6.42
Origin of the lamina propria dendritic cell network. Immunity (2009) 5.95
Langerhans cells arise from monocytes in vivo. Nat Immunol (2006) 5.46
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science (2010) 4.67
Migratory fate and differentiation of blood monocyte subsets. Immunobiology (2006) 4.30
Unravelling mononuclear phagocyte heterogeneity. Nat Rev Immunol (2010) 4.25
Deciphering the transcriptional network of the dendritic cell lineage. Nat Immunol (2012) 4.17
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity (2006) 4.04
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques. Proc Natl Acad Sci U S A (2004) 3.85
Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat Biotechnol (2007) 3.75
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. Science (2013) 3.74
Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. J Exp Med (2007) 3.64
Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody. J Natl Cancer Inst (2005) 3.58
Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science (2008) 3.51
Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J Exp Med (2006) 3.43
Comparison of gene expression profiles between human and mouse monocyte subsets. Blood (2009) 3.15
Activation of leukocyte beta2 integrins by conversion from bent to extended conformations. Immunity (2006) 3.11
Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat Med (2011) 3.06
Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations. J Immunol (2008) 3.04
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci U S A (2006) 3.00
Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. Clin Gastroenterol Hepatol (2004) 2.99
Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res (2005) 2.91
Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes. J Exp Med (2008) 2.73
Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med (2004) 2.68
Molecular characterization of lymphatic endothelial cells. Proc Natl Acad Sci U S A (2002) 2.68
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 2.61
Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell (2007) 2.48
Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2. Cancer Res (2006) 2.40
Identification of the target self-antigens in reperfusion injury. J Exp Med (2006) 2.38
Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. J Clin Invest (2011) 2.37
Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1. Proc Natl Acad Sci U S A (2007) 2.27
Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization. Immunity (2004) 2.27
Development of an internet-based cohort of patients with inflammatory bowel diseases (CCFA Partners): methodology and initial results. Inflamm Bowel Dis (2012) 2.23
Modulation of dendritic cell trafficking to and from the airways. J Immunol (2006) 2.17
Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial. Am J Gastroenterol (2008) 2.16
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med (2009) 2.12
Overexpression of VEGF-C causes transient lymphatic hyperplasia but not increased lymphangiogenesis in regenerating skin. Circ Res (2005) 2.08
The incidence and management of infusion reactions to infliximab: a large center experience. Am J Gastroenterol (2003) 2.06
Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells. Eur J Immunol (2008) 2.05
Monocyte trafficking in acute and chronic inflammation. Trends Immunol (2011) 2.05
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. Gastroenterology (2004) 2.02
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. J Exp Med (2013) 1.99
Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction. Immunity (2004) 1.98
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity (2012) 1.98
The natural history of milk allergy in an observational cohort. J Allergy Clin Immunol (2012) 1.96
CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen. J Exp Med (2011) 1.95
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology (2010) 1.92
Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology (2008) 1.89
Importance of force linkage in mechanochemistry of adhesion receptors. Biochemistry (2006) 1.87
Identification of transcriptional regulators in the mouse immune system. Nat Immunol (2013) 1.79
Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. J Exp Med (2013) 1.77
Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. J Exp Med (2008) 1.76
Regulation of the migration and survival of monocyte subsets by chemokine receptors and its relevance to atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 1.76
Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signaling. Arterioscler Thromb Vasc Biol (2010) 1.75
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. Gastroenterology (2003) 1.70
Optimization of methods to study pulmonary dendritic cell migration reveals distinct capacities of DC subsets to acquire soluble versus particulate antigen. J Immunol Methods (2008) 1.69
Therapeutic lymphangiogenesis with human recombinant VEGF-C. FASEB J (2002) 1.67
The immune response in inflammatory bowel disease. Am J Gastroenterol (2007) 1.67
A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology (2007) 1.64
Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes. Immunity (2006) 1.63
The transcriptional landscape of αβ T cell differentiation. Nat Immunol (2013) 1.61
Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1. J Biol Chem (2002) 1.61
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest (2007) 1.60
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology (2007) 1.60
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. J Clin Invest (2013) 1.57
Monoclonal antibodies, immunogenicity, and associated infusion reactions. Mt Sinai J Med (2005) 1.57
RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice. Mol Ther (2009) 1.55
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. Cancer Res (2007) 1.53
Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells. Blood (2012) 1.53
Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis. Gut (2010) 1.53
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet (2012) 1.52
Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling. Blood (2007) 1.52
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem (2006) 1.52
Recent understanding of IBD pathogenesis: implications for future therapies. Inflamm Bowel Dis (2006) 1.51
Lymphangiogenesis and tumor metastasis. Cell Tissue Res (2003) 1.50
The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. J Clin Invest (2010) 1.50
Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring. Proc Natl Acad Sci U S A (2004) 1.49
Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells. Gastroenterology (2002) 1.49
The fibroblast: sentinel cell and local immune modulator in tumor tissue. Int J Cancer (2004) 1.48
CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions. Gastroenterology (2007) 1.47
Hypercholesterolemic mice exhibit lymphatic vessel dysfunction and degeneration. Am J Pathol (2009) 1.47
Defects in CD8+ regulatory T cells in the lamina propria of patients with inflammatory bowel disease. J Immunol (2005) 1.43
Oral tolerance and its relation to food hypersensitivities. J Allergy Clin Immunol (2005) 1.42
Lipopolysaccharide or whole bacteria block the conversion of inflammatory monocytes into dendritic cells in vivo. J Exp Med (2003) 1.39
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.39
Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth. Am J Pathol (2002) 1.35
Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions. Proc Natl Acad Sci U S A (2004) 1.35
Failure to induce oral tolerance to a soluble protein in patients with inflammatory bowel disease. Gastroenterology (2004) 1.33
Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity. Proc Natl Acad Sci U S A (2006) 1.32
Lymphatic endothelium: morphological, molecular and functional properties. J Cell Biol (2003) 1.31
An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2. Proc Natl Acad Sci U S A (2005) 1.30
Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. J Allergy Clin Immunol (2009) 1.30
Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis. Inflamm Bowel Dis (2010) 1.28