Published in Curr Opin Otolaryngol Head Neck Surg on October 01, 2009
A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea. Development (2012) 1.25
Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti. Hear Res (2010) 1.22
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PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice. Neuroreport (2014) 0.85
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Where hearing starts: the development of the mammalian cochlea. J Anat (2015) 0.79
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Sensational placodes: neurogenesis in the otic and olfactory systems. Dev Biol (2014) 0.78
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife (2016) 0.78
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Hedgehog signaling in development and cancer. Dev Cell (2008) 6.60
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Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nat Med (2005) 5.17
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Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci (2000) 3.88
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Sox2 is required for sensory organ development in the mammalian inner ear. Nature (2005) 3.58
Planar cell polarity signaling: from fly development to human disease. Annu Rev Genet (2008) 3.43
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Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature (2008) 3.21
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96
Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci (2004) 2.93
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Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development (2006) 2.70
Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo. J Neurosci (2003) 2.67
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A (2008) 2.52
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development (2005) 2.36
FGFR1 is required for the development of the auditory sensory epithelium. Neuron (2002) 2.35
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From placode to polarization: new tunes in inner ear development. Development (2004) 2.12
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell (2009) 2.11
Expression of Prox1 during mouse cochlear development. J Comp Neurol (2006) 1.93
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Specification of the mammalian cochlea is dependent on Sonic hedgehog. Genes Dev (2002) 1.71
Human nonsyndromic hereditary deafness DFNA17 is due to a mutation in nonmuscle myosin MYH9. Am J Hum Genet (2000) 1.68
Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4). Am J Hum Genet (2004) 1.67
Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairment. Dev Dyn (2007) 1.61
Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn (2007) 1.59
Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. Development (2007) 1.58
Fibroblast growth factor signaling regulates pillar cell development in the organ of corti. J Neurosci (2002) 1.54
Planar cell polarity genes regulate polarized extracellular matrix deposition during frog gastrulation. Curr Biol (2005) 1.53
Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns (2007) 1.52
Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer. Otol Neurotol (2007) 1.47
Potassium ion recycling pathway via gap junction systems in the mammalian cochlea and its interruption in hereditary nonsyndromic deafness. Med Electron Microsc (2000) 1.39
Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice. J Assoc Res Otolaryngol (2000) 1.38
Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol (2008) 1.35
Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci (2008) 1.33
A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome. Am J Hum Genet (2006) 1.31
Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci (2008) 1.30
Primary cilia in planar cell polarity regulation of the inner ear. Curr Top Dev Biol (2008) 1.23
Cellular growth and rearrangement during the development of the mammalian organ of Corti. Dev Dyn (2004) 1.23
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development (2009) 1.19
The plane facts of PCP in the CNS. Neuron (2008) 1.17
Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia. Dev Biol (2008) 1.13
Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development (2008) 1.13
Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol (2008) 1.07
Hearing loss in a mouse model of Muenke syndrome. Hum Mol Genet (2008) 1.07
Genetic heterogeneity of deafness phenotypes linked to DFNA4. Am J Med Genet A (2005) 1.05
Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development. Gene Expr Patterns (2009) 1.02
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Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia. Biochim Biophys Acta (2008) 0.97
Recent advances in hair cell regeneration research. Curr Opin Otolaryngol Head Neck Surg (2008) 0.94
Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti. J Neurosci (2008) 0.94
Deafness due to Pro250Arg mutation of FGFR3. Lancet (1998) 0.93
Genetic and pharmacological intervention for treatment/prevention of hearing loss. J Commun Disord (2008) 0.91
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A (2008) 2.52
A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea. Development (2012) 1.25
Cellular commitment and differentiation in the organ of Corti. Int J Dev Biol (2007) 1.25
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol (2013) 1.09
CD44 is a marker for the outer pillar cells in the early postnatal mouse inner ear. J Assoc Res Otolaryngol (2010) 1.03
XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus. Mol Biol Cell (2003) 0.93