Published in Proc Natl Acad Sci U S A on July 23, 2009
Effect of concentration on the accuracy of convective imaging distribution of a gadolinium-based surrogate tracer. J Neurosurg (2011) 1.87
Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics. Sci Rep (2013) 1.51
Cell therapeutics in Parkinson's disease. Neurotherapeutics (2011) 1.32
Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors. PLoS One (2011) 1.10
In vivo imaging of endogenous neural stem cells in the adult brain. World J Stem Cells (2015) 1.01
Angiogenic factors stimulate growth of adult neural stem cells. PLoS One (2010) 0.98
Multi-session transcranial direct current stimulation (tDCS) elicits inflammatory and regenerative processes in the rat brain. PLoS One (2012) 0.93
Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther (2014) 0.86
Cholera toxin regulates a signaling pathway critical for the expansion of neural stem cell cultures from the fetal and adult rodent brains. PLoS One (2010) 0.85
Stress, glucocorticoid hormones, and hippocampal neural progenitor cells: implications to mood disorders. Front Physiol (2015) 0.85
The STAT3-Ser/Hes3 signaling axis: an emerging regulator of endogenous regeneration and cancer growth. Front Physiol (2013) 0.83
Endogenous neural precursors influence grafted neural stem cells and contribute to neuroprotection in the parkinsonian rat. Eur J Neurosci (2012) 0.82
Growing neural stem cells from conventional and nonconventional regions of the adult rodent brain. J Vis Exp (2013) 0.82
Induction of angiopoietin-2 after spinal cord injury. Neuroscience (2011) 0.82
Brain homeostasis: VEGF receptor 1 and 2-two unequal brothers in mind. Cell Mol Life Sci (2013) 0.80
Neurovascular signals suggest a propagation mechanism for endogenous stem cell activation along blood vessels. CNS Neurol Disord Drug Targets (2012) 0.79
Strategies for regenerating striatal neurons in the adult brain by using endogenous neural stem cells. Neurol Res Int (2011) 0.79
Expression profiles of the nuclear receptors and their transcriptional coregulators during differentiation of neural stem cells. Horm Metab Res (2012) 0.79
Angiopoietin-2 is vasoprotective in the acute phase of cerebral ischemia. J Cereb Blood Flow Metab (2012) 0.78
Therapeutic application of neural stem cells and adult neurogenesis for neurodegenerative disorders: regeneration and beyond. Eur J Neurodegener Dis (2015) 0.77
Fast, potent pharmacological expansion of endogenous hes3+/sox2+ cells in the adult mouse and rat hippocampus. PLoS One (2012) 0.77
Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release. J Biol Chem (2014) 0.76
The significance of Notch ligand expression in the peripheral blood of children with hand, foot and mouth disease (HFMD). BMC Infect Dis (2014) 0.75
Spicing up endogenous neural stem cells: aromatic-turmerone offers new possibilities for tackling neurodegeneration. Stem Cell Res Ther (2014) 0.75
Concise Review: Reprogramming, Behind the Scenes: Noncanonical Neural Stem Cell Signaling Pathways Reveal New, Unseen Regulators of Tissue Plasticity With Therapeutic Implications. Stem Cells Transl Med (2015) 0.75
Phosphodiesterase 7 inhibition induces dopaminergic neurogenesis in hemiparkinsonian rats. Stem Cells Transl Med (2015) 0.75
Brain-Derived Neurotrophic Factor Increases Synaptic Protein Levels via the MAPK/Erk Signaling Pathway and Nrf2/Trx Axis Following the Transplantation of Neural Stem Cells in a Rat Model of Traumatic Brain Injury. Neurochem Res (2017) 0.75
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science (1997) 15.48
Parkinson's disease: mechanisms and models. Neuron (2003) 14.84
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell (1996) 13.95
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell (2004) 12.67
Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med (2001) 9.51
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science (1983) 9.41
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science (2004) 9.10
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09
Endothelial/pericyte interactions. Circ Res (2005) 8.24
Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A (2004) 7.51
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat Med (2006) 7.21
Vascular niche for adult hippocampal neurogenesis. J Comp Neurol (2000) 7.19
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature (2002) 6.51
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol (2003) 6.21
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell (2004) 5.50
Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Nat Med (2006) 5.49
Notch signalling regulates stem cell numbers in vitro and in vivo. Nature (2006) 5.49
Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol (2008) 4.42
Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev (2004) 4.14
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (2000) 3.89
Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development (2004) 3.75
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol (1999) 3.63
A vasculature-associated niche for undifferentiated spermatogonia in the mouse testis. Science (2007) 3.60
Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell (2008) 3.34
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J Clin Invest (2008) 2.91
Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci (2004) 2.84
Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations. NMR Biomed (2004) 2.74
In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J Neurosci (1996) 2.72
IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nat Neurosci (2006) 2.71
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation. Development (2004) 2.65
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. J Clin Invest (2002) 2.26
Neurovascular signalling defects in neurodegeneration. Nat Rev Neurosci (2008) 2.15
Dyskinesias following neural transplantation in Parkinson's disease. Nat Neurosci (2002) 1.74
Potency and fate specification in CNS stem cell populations in vitro. Cell Stem Cell (2008) 1.54
Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine. PLoS Biol (2007) 1.48
Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine. Neuroscience (1995) 1.37
Effect of ependymal and pial surfaces on convection-enhanced delivery. J Neurosurg (2008) 1.17
Neurotrophic factors as a therapeutic target for Parkinson's disease. Expert Opin Ther Targets (2008) 1.05
Signaling pathways controlling neural stem cells slow progressive brain disease. Cold Spring Harb Symp Quant Biol (2008) 1.04
Notch signalling regulates stem cell numbers in vitro and in vivo. Nature (2006) 5.49
High-field MRI of brain cortical substructure based on signal phase. Proc Natl Acad Sci U S A (2007) 5.02
MRI detection of single particles for cellular imaging. Proc Natl Acad Sci U S A (2004) 3.67
In vivo detection of single cells by MRI. Magn Reson Med (2006) 2.75
Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations. NMR Biomed (2004) 2.74
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. J Neurosci (2010) 2.73
Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. Blood (2003) 2.50
Sizing it up: cellular MRI using micron-sized iron oxide particles. Magn Reson Med (2005) 2.38
Laminar specificity of functional MRI onset times during somatosensory stimulation in rat. Proc Natl Acad Sci U S A (2002) 2.29
Functional reactivity of cerebral capillaries. J Cereb Blood Flow Metab (2007) 2.10
Spatial flow-volume dissociation of the cerebral microcirculatory response to mild hypercapnia. Neuroimage (2006) 2.09
Effect of concentration on the accuracy of convective imaging distribution of a gadolinium-based surrogate tracer. J Neurosurg (2011) 1.87
In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI. Neuroimage (2004) 1.85
Imaging cortical anatomy by high-resolution MR at 3.0T: detection of the stripe of Gennari in visual area 17. Magn Reson Med (2002) 1.83
Successful and safe perfusion of the primate brainstem: in vivo magnetic resonance imaging of macromolecular distribution during infusion. J Neurosurg (2002) 1.79
Extensive heterogeneity in white matter intensity in high-resolution T2*-weighted MRI of the human brain at 7.0 T. Neuroimage (2006) 1.78
MRI of the basement membrane using charged nanoparticles as contrast agents. Magn Reson Med (2008) 1.77
Low-field paramagnetic resonance imaging of tumor oxygenation and glycolytic activity in mice. J Clin Invest (2008) 1.71
Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging. Neuroimage (2002) 1.70
Real-time imaging of convection-enhanced delivery of viruses and virus-sized particles. J Neurosurg (2007) 1.68
Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1- 13C]pyruvate and 13C magnetic resonance spectroscopic imaging. Magn Reson Med (2010) 1.65
Magnetic resonance imaging of the migration of neuronal precursors generated in the adult rodent brain. Neuroimage (2006) 1.59
Manganese-enhanced magnetic resonance imaging (MEMRI). NMR Biomed (2004) 1.59
Real-time image-guided direct convective perfusion of intrinsic brainstem lesions. Technical note. J Neurosurg (2007) 1.51
Convective distribution of macromolecules in the primate brain demonstrated using computerized tomography and magnetic resonance imaging. J Neurosurg (2003) 1.48
Manganese-enhanced magnetic resonance imaging of mouse brain after systemic administration of MnCl2: dose-dependent and temporal evolution of T1 contrast. Magn Reson Med (2005) 1.47
Convection-enhanced delivery of M13 bacteriophage to the brain. J Neurosurg (2012) 1.42
Functional MRI of the rodent somatosensory pathway using multislice echo planar imaging. Magn Reson Med (2004) 1.40
Functional MRI impulse response for BOLD and CBV contrast in rat somatosensory cortex. Magn Reson Med (2007) 1.39
High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents. Clin Cancer Res (2006) 1.38
Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. Am J Psychiatry (2010) 1.34
Safety and efficacy of convection-enhanced delivery of gemcitabine or carboplatin in a malignant glioma model in rats. J Neurosurg (2003) 1.30
Cell labeling for magnetic resonance imaging with the T1 agent manganese chloride. NMR Biomed (2006) 1.30
Image-guided convection-enhanced delivery of muscimol to the primate brain. J Neurosurg (2010) 1.29
Temporal dynamics of the BOLD fMRI impulse response. Neuroimage (2004) 1.28
A specific survival response in dopamine neurons at most risk in Parkinson's disease. J Neurosci (2006) 1.28
BOLD and CBV-weighted functional magnetic resonance imaging of the rat somatosensory system. Magn Reson Med (2006) 1.27
Real-time, image-guided, convection-enhanced delivery of interleukin 13 bound to pseudomonas exotoxin. Clin Cancer Res (2006) 1.23
In vivo labeling of adult neural progenitors for MRI with micron sized particles of iron oxide: quantification of labeled cell phenotype. Neuroimage (2008) 1.20
Mapping resting-state functional connectivity using perfusion MRI. Neuroimage (2008) 1.20
Direct imaging of macrovascular and microvascular contributions to BOLD fMRI in layers IV-V of the rat whisker-barrel cortex. Neuroimage (2011) 1.19
Real-time in vivo imaging of the convective distribution of a low-molecular-weight tracer. J Neurosurg (2005) 1.17
Effect of ependymal and pial surfaces on convection-enhanced delivery. J Neurosurg (2008) 1.17
Image-guided convection-enhanced delivery of gemcitabine to the brainstem. J Neurosurg (2007) 1.17
Functional MRI detection of bilateral cortical reorganization in the rodent brain following peripheral nerve deafferentation. Neuroimage (2007) 1.16
Temporal changes in the T1 and T2 relaxation rates (DeltaR1 and DeltaR2) in the rat brain are consistent with the tissue-clearance rates of elemental manganese. Magn Reson Med (2009) 1.13
Antibody-mediated cell labeling of peripheral T cells with micron-sized iron oxide particles (MPIOs) allows single cell detection by MRI. Contrast Media Mol Imaging (2007) 1.12
Noninvasive imaging of the functional effects of anti-VEGF therapy on tumor cell extravasation and regional blood volume in an experimental brain metastasis model. Clin Exp Metastasis (2009) 1.10
Characterization of T(2)* heterogeneity in human brain white matter. Magn Reson Med (2009) 1.10
Dynamic activity-induced manganese-dependent contrast magnetic resonance imaging (DAIM MRI). Magn Reson Med (2002) 1.10
Convection perfusion of glucocerebrosidase for neuronopathic Gaucher's disease. Ann Neurol (2005) 1.08
CPEB1 regulates beta-catenin mRNA translation and cell migration in astrocytes. Glia (2008) 1.08
Cocaine increases the intracellular calcium concentration in brain independently of its cerebrovascular effects. J Neurosci (2006) 1.07
Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model. Stroke (2011) 1.06
Brain redox imaging using blood-brain barrier-permeable nitroxide MRI contrast agent. J Cereb Blood Flow Metab (2008) 1.06
Early role of CD4+ Th1 cells and antibodies in HER-2 adenovirus vaccine protection against autochthonous mammary carcinomas. J Immunol (2005) 1.06
Selective ablation of nociceptive neurons for elimination of hyperalgesia and neurogenic inflammation. J Neurosurg (2005) 1.03
Manganese enhanced magnetic resonance imaging. Curr Pharm Biotechnol (2004) 1.02
Detection of cortical laminar architecture using manganese-enhanced MRI. J Neurosci Methods (2007) 1.02
The effect of a PP2A inhibitor on the nuclear receptor corepressor pathway in glioma. J Neurosurg (2010) 1.01
Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke. Stroke (2012) 1.01
Cediranib/AZD2171 inhibits bone and brain metastasis in a preclinical model of advanced prostate cancer. Cancer Res (2010) 1.01
alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. Am J Physiol Heart Circ Physiol (2002) 1.01
Generating neurons from stem cells. Methods Mol Biol (2008) 1.00
The effect of hyperoxygenation on T1 relaxation time in vitro. Acad Radiol (2003) 0.99
Ipsilateral cortical fMRI responses after peripheral nerve damage in rats reflect increased interneuron activity. Proc Natl Acad Sci U S A (2009) 0.99
Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells. Curr Biol (2012) 0.98
Angiogenic factors stimulate growth of adult neural stem cells. PLoS One (2010) 0.98
BOLD fMRI and somatosensory evoked potentials are well correlated over a broad range of frequency content of somatosensory stimulation of the rat forepaw. Brain Res (2007) 0.97
B1 homogenization in MRI by multilayer coupled coils. IEEE Trans Med Imaging (2009) 0.97
Controlled aggregation of ferritin to modulate MRI relaxivity. Biophys J (2008) 0.97
The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol. Hum Mol Genet (2012) 0.97
Improved stem cell MR detectability in animal models by modification of the inhalation gas. Mol Imaging (2005) 0.96
β-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas. Proc Natl Acad Sci U S A (2012) 0.96
Thalamocortical inputs show post-critical-period plasticity. Neuron (2012) 0.96
Layer specific tracing of corticocortical and thalamocortical connectivity in the rodent using manganese enhanced MRI. Neuroimage (2008) 0.95
Development of a MR-visible compound for tracing neuroanatomical connections in vivo. Neuron (2011) 0.95
Medical oncology: treatment and management of malignant gliomas. Nat Rev Clin Oncol (2010) 0.94
Convertible manganese contrast for molecular and cellular MRI. Magn Reson Med (2008) 0.94
Differential effects of anesthetics on cocaine's pharmacokinetic and pharmacodynamic effects in brain. Eur J Neurosci (2009) 0.94
MRI detection of ferritin iron overload and associated neuronal pathology in iron regulatory protein-2 knockout mice. Brain Res (2003) 0.94
Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover. Proc Natl Acad Sci U S A (2013) 0.93
HLA-DRB5*0101 and -DRB1*1501 expression in the multiple sclerosis-associated HLA-DR15 haplotype. J Neuroimmunol (2005) 0.92
A dual CT-MR dendrimer contrast agent as a surrogate marker for convection-enhanced delivery of intracerebral macromolecular therapeutic agents. Contrast Media Mol Imaging (2008) 0.92
Selective opening of the blood-tumor barrier by a nitric oxide donor and long-term survival in rats with C6 gliomas. J Neurosurg (2003) 0.92
Mapping prefrontal circuits in vivo with manganese-enhanced magnetic resonance imaging in monkeys. J Neurosci (2008) 0.91
Magnetic resonance imaging assessment of a murine model of recessive polycystic kidney disease. Comp Med (2002) 0.91
Bevacizumab used for the treatment of severe, refractory perilesional edema due to an arteriovenous malformation treated with stereotactic radiosurgery. J Neurosurg (2012) 0.91
Improving the radiosensitivity of radioresistant and hypoxic glioblastoma. Future Oncol (2010) 0.91
Manganese cell labeling of murine hepatocytes using manganese(III)-transferrin. Contrast Media Mol Imaging (2008) 0.91
EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate. Magn Reson Med (2012) 0.90
Local distribution and toxicity of prolonged hippocampal infusion of muscimol. J Neurosurg (2005) 0.90
Manganese enhanced magnetic resonance imaging of normal and ischemic canine heart. Magn Reson Med (2005) 0.90
Identification of repurposed small molecule drugs for chordoma therapy. Cancer Biol Ther (2013) 0.90
3D mapping of somatotopic reorganization with small animal functional MRI. Neuroimage (2009) 0.89
Magnetic resonance mapping of transplanted endothelial progenitor cells for therapeutic neovascularization in ischemic heart disease. Eur J Cardiothorac Surg (2004) 0.89