PubRank

Graça Raposo

Author PubWeight™ 206.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol 2006 13.29
2 Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol 2009 6.96
3 Exosomal-like vesicles are present in human blood plasma. Int Immunol 2005 6.04
4 Exosomes: a common pathway for a specialized function. J Biochem 2006 5.79
5 Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol 2004 5.71
6 Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol 2009 5.44
7 NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell 2006 5.35
8 Cells release prions in association with exosomes. Proc Natl Acad Sci U S A 2004 5.17
9 Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 2003 4.94
10 The biogenesis and functions of exosomes. Traffic 2002 4.49
11 Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol 2014 3.97
12 Cells respond to mechanical stress by rapid disassembly of caveolae. Cell 2011 3.55
13 Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature 2007 3.51
14 Exosome secretion: molecular mechanisms and roles in immune responses. Traffic 2011 3.36
15 TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol 2002 3.28
16 A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med 2006 3.21
17 As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles 2013 3.01
18 Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science 2008 2.88
19 Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol 2006 2.79
20 The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res 2005 2.71
21 Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol 2007 2.69
22 Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell 2010 2.67
23 Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell 2005 2.56
24 Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol 2008 2.56
25 BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell 2006 2.37
26 ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood 2005 2.34
27 A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell 2006 2.29
28 Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol 2007 2.28
29 Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature 2008 2.15
30 Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol 2003 2.12
31 BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell 2006 2.11
32 Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol 2005 2.09
33 Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles 2012 2.06
34 ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol 2003 2.02
35 AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol 2009 1.99
36 MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic 2009 1.98
37 Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci 2013 1.98
38 A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A 2003 1.86
39 Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol 2004 1.86
40 Endosomes, exosomes and Trojan viruses. Trends Microbiol 2004 1.84
41 The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell 2011 1.82
42 The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci 2007 1.80
43 Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells. Nat Immunol 2005 1.76
44 TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J 2004 1.71
45 Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res 2009 1.63
46 T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology 2007 1.60
47 Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol 2013 1.59
48 Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J 2006 1.53
49 ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. Curr Biol 2009 1.52
50 Synchronization of secretory protein traffic in populations of cells. Nat Methods 2012 1.41
51 Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells. Int Immunol 2002 1.41
52 Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol 2003 1.40
53 Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17. Mol Biol Cell 2006 1.37
54 Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol Cell 2008 1.33
55 Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic 2009 1.30
56 N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J Biol Chem 2009 1.28
57 Exosomes: a bubble ride for prions? Traffic 2005 1.24
58 Rab27b regulates mast cell granule dynamics and secretion. Traffic 2007 1.22
59 Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates. Mol Biol Cell 2002 1.21
60 Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase. Mol Biol Cell 2003 1.18
61 The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J Cell Biol 2007 1.17
62 Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes. J Biol Chem 2007 1.17
63 Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Nat Cell Biol 2011 1.16
64 Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J Exp Med 2002 1.16
65 Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes. J Cell Sci 2005 1.13
66 Prions and exosomes: from PrPc trafficking to PrPsc propagation. Blood Cells Mol Dis 2005 1.12
67 Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol 2010 1.11
68 Rab6-interacting protein 1 links Rab6 and Rab11 function. Traffic 2007 1.11
69 Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration. Biol Cell 2007 1.11
70 Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB. Proc Natl Acad Sci U S A 2004 1.11
71 The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition. Hum Mol Genet 2009 1.06
72 Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex. Mol Biol Cell 2010 1.06
73 ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane. Traffic 2009 1.05
74 BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells. Proc Natl Acad Sci U S A 2013 1.04
75 The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus. Hum Mol Genet 2008 1.03
76 The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes. Mol Biol Cell 2010 1.02
77 General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol 2007 1.01
78 A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting. Mol Biol Cell 2012 1.00
79 Immature dendritic cells (DCs) use chemokines and intercellular adhesion molecule (ICAM)-1, but not DC-specific ICAM-3-grabbing nonintegrin, to stimulate CD4+ T cells in the absence of exogenous antigen. J Immunol 2004 0.98
80 PMEL: a pigment cell-specific model for functional amyloid formation. Pigment Cell Melanoma Res 2013 0.97
81 Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet 2011 0.97
82 HLA-DR4 molecules in neuroendocrine epithelial cells associate to a heterogeneous repertoire of cytoplasmic and surface self peptides. J Immunol 2002 0.96
83 Microphthalmia transcription factor induces both retinal pigmented epithelium and neural crest melanocytes from neuroretina cells. J Biol Chem 2004 0.96
84 Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. Mol Biol Cell 2004 0.96
85 Identification and characterization of multiple novel Rab-myosin Va interactions. Mol Biol Cell 2013 0.94
86 Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes. Mol Biol Cell 2012 0.94
87 BCR-bound antigen is targeted to exosomes in human follicular lymphoma B-cells. Biol Cell 2006 0.93
88 Control of MT1-MMP transport by atypical PKC during breast-cancer progression. Proc Natl Acad Sci U S A 2014 0.91
89 LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route. Dev Cell 2013 0.91
90 AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis. Mol Biol Cell 2007 0.91
91 SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models. Blood 2012 0.91
92 Rab30 is required for the morphological integrity of the Golgi apparatus. Biol Cell 2011 0.90
93 Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic. PLoS Genet 2011 0.90
94 The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function. Proc Natl Acad Sci U S A 2011 0.87
95 Prion strains are differentially released through the exosomal pathway. Cell Mol Life Sci 2014 0.86
96 LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function. Traffic 2015 0.85
97 Myosin VI regulates actin dynamics and melanosome biogenesis. Traffic 2012 0.83
98 Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties. Cell Mol Life Sci 2011 0.83
99 Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor. J Biol Chem 2013 0.82
100 Analysis of de novo Golgi complex formation after enzyme-based inactivation. Mol Biol Cell 2007 0.81
101 In vitro differentiation of retinal pigment epithelium from adult retinal stem cells. Pigment Cell Melanoma Res 2010 0.80
102 Melanosomes and MHC class II antigen-processing compartments: a tinted view of intracellular trafficking and immunity. Immunol Res 2003 0.80
103 Caveolins and flotillin-2 are present in the blood stages of Plasmodium vivax. Parasitol Res 2006 0.80
104 [Exosomes: carriers of prions?]. Med Sci (Paris) 2005 0.77
105 Membranes and organelles. Curr Opin Cell Biol 2008 0.76
106 Phosphoinositide 3-kinase activation by Igbeta controls de novo formation of an antigen-processing compartment. J Biol Chem 2002 0.76
107 Graça Raposo: melanosomes, more than skin deep. Interviewed by Caitlin Sedwick. J Cell Biol 2012 0.75
108 [Biogenesis of melanosomes - the chessboard of pigmentation]. Med Sci (Paris) 2011 0.75
109 Accelerated recycling of transferrin receptor in Theileria-transformed B cells. Cell Microbiol 2005 0.75