PubRank

E H Ulm

Author PubWeight™ 39.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A new class of angiotensin-converting enzyme inhibitors. Nature 1980 3.03
2 Enalapril maleate and a lysine analogue (MK-521): disposition in man. Br J Clin Pharmacol 1982 2.49
3 Enalapril maleate and a lysine analogue (MK-521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system. Br J Clin Pharmacol 1982 1.95
4 The physiological disposition and metabolism of enalapril maleate in laboratory animals. Drug Metab Dispos 1982 1.79
5 Alpha-isopropylmalate synthase from yeast: purification, kinetic studies, and effect of ligands on stability. J Bacteriol 1972 1.66
6 Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor responses in vivo. J Pharmacol Exp Ther 1981 1.44
7 Effect of experimental diabetes on elimination kinetics of diflunisal in rats. Drug Metab Dispos 1989 1.14
8 Enalapril maleate (MK-421), a potent, nonsulfhydryl angiotensin-converting enzyme inhibitor: absorption, disposition, and metabolism in man. Drug Metab Rev 1983 1.04
9 Role of oleate in the regulation of "neutral" rabbit liver fructose 1,6-diphosphatase activity. J Biol Chem 1973 0.99
10 Differential renal handling of angiotensin-converting enzyme inhibitors enalaprilat and lisinopril in rats. Drug Metab Dispos 1988 0.97
11 Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors. Drug Metab Dispos 2001 0.94
12 A Phase I study of LGD1069 in adults with advanced cancer. Clin Cancer Res 1999 0.94
13 Novel renin inhibitors containing the amino acid statine. Nature 1983 0.93
14 Phosphorus-containing inhibitors of angiotensin-converting enzyme. Proc Natl Acad Sci U S A 1982 0.93
15 Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives. J Med Chem 1983 0.92
16 The reaction of PGA1 with sulfhydryl groups; a component in the binding of A-type prostaglandins to proteins. Prostaglandins 1975 0.88
17 Urinary excretion kinetics of famotidine in rats. Drug Metab Dispos 1987 0.88
18 Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes. Drug Metab Dispos 1998 0.86
19 Biotransformation of lovastatin. I. Structure elucidation of in vitro and in vivo metabolites in the rat and mouse. Drug Metab Dispos 1990 0.85
20 Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid. Clin Cancer Res 1996 0.84
21 Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine. J Med Chem 1985 0.84
22 Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate. Drug Metab Dispos 1996 0.83
23 Biotransformation of lovastatin. V. Species differences in in vivo metabolite profiles of mouse, rat, dog, and human. Drug Metab Dispos 1994 0.83
24 Fructose-1, 6-diphosphatase from rabbit liver. Methods Enzymol 1975 0.82
25 Kinetic studies on the competition between famotidine and cimetidine in rats. Evidence of multiple renal secretory systems for organic cations. Drug Metab Dispos 1988 0.81
26 Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations. J Med Chem 1986 0.81
27 Benzolactams. A new class of converting enzyme inhibitors. Biochem Biophys Res Commun 1983 0.81
28 Renin inhibitors. Statine-containing tetrapeptides with varied hydrophobic carboxy termini. J Med Chem 1987 0.80
29 Phase I study of 9-cis-retinoic acid (ALRT1057 capsules) in adults with advanced cancer. Clin Cancer Res 1998 0.80
30 Total serum angiotensin converting enzyme activity in rats and dogs after enalapril maleate (MK-421). Life Sci 1982 0.79
31 Disposition of enalapril and its diacid metabolite, enalaprilat, in a perfused rat liver preparation. Presence of a diffusional barrier for enalaprilat into hepatocytes. Drug Metab Dispos 1984 0.79
32 A 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin A in rabbit kidney. Proc Natl Acad Sci U S A 1976 0.78
33 A uniquely potent renin inhibitor and its unanticipated plasma binding component. J Med Chem 1985 0.78
34 Possible mechanisms for reduced plasma clearance of diflunisal in rat experimental renal failure. J Pharmacol Exp Ther 1986 0.78
35 Disposition of enalapril in the perfused rat intestine-liver preparation: absorption, metabolism and first-pass effect. J Pharmacol Exp Ther 1985 0.78
36 Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey. Cancer Res 1995 0.77
37 Renal effects of enalapril in dogs. Kidney Int Suppl 1987 0.75
38 Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa. Clin Sci Mol Med Suppl 1978 0.75
39 Azapeptides: a new class of angiotensin-converting enzyme inhibitors. Biochem Biophys Res Commun 1984 0.75
40 Quantitative determination of L-364,718, a novel cholecystokinin antagonist, by solid-phase extraction and high-performance liquid chromatography. J Chromatogr 1988 0.75
41 Species-dependent enantioselective plasma protein binding of MK-571, a potent leukotriene D4 antagonist. Drug Metab Dispos 1990 0.75
42 Dose-dependent pharmacokinetics of MK-417, a potent carbonic anhydrase inhibitor, in rabbits following single and multiple doses. Drug Metab Dispos 1991 0.75
43 Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats. J Pharmacol Exp Ther 1987 0.75
44 Dipeptide mimics. Conformationally restricted inhibitors of angiotensin-converting enzyme. Biochem Biophys Res Commun 1983 0.75
45 Involvement of cytosol proteins in oleate activation of rabbit liver fructose-1,6-diphosphatase. J Biol Chem 1975 0.75
46 Antihypertensive activity of some novel pyridinylidene arylurea derivatives in spontaneously hypertensive rats. Experientia 1979 0.75
47 Renin inhibitors containing 2-substituted statine. Biochem Soc Trans 1984 0.75
48 Renin inhibitors containing hydrophilic groups. Tetrapeptides with enhanced aqueous solubility and nanomolar potency. J Med Chem 1988 0.75
49 Design of proteolytically-stable, peptidal renin inhibitors and determination of their fate in vivo. Regul Pept Suppl 1985 0.75
50 Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyl tripeptide analogues of enalapril. J Med Chem 1985 0.75
51 Dose-dependent stereopharmacokinetics of 5,6-dihydro-4H-4(isobutylamino)thieno(2,3-B)thiopyran-2-sulfonamide-7,7 -dioxide , a potent carbonic anhydrase inhibitor, in rats. Drug Metab Dispos 1991 0.75
52 Dose-dependent kinetics of cilastatin in laboratory animals. Drug Metab Dispos 1989 0.75