Published in Evid Based Complement Alternat Med on June 07, 2011
Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats. Evid Based Complement Alternat Med (2010) 0.95
Electroacupuncture-Induced Neuroprotection against Cerebral Ischemia in Rats: Role of the Dopamine D2 Receptor. Evid Based Complement Alternat Med (2013) 0.83
San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways. Evid Based Complement Alternat Med (2011) 0.82
Effects of traditional Chinese herbal medicine San-Huang-Xie-Xin-Tang on gastrointestinal motility in mice. World J Gastroenterol (2015) 0.78
San-Huang-Xie-Xin-Tang Constituents Exert Drug-Drug Interaction of Mutual Reinforcement at Both Pharmacodynamics and Pharmacokinetic Level: A Review. Front Pharmacol (2016) 0.76
Rapid HPLC Quantification Approach for Detection of Active Constituents in Modern Combinatorial Formula, San-Huang-Xie-Xin-Tang (SHXXT). Front Pharmacol (2016) 0.75
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Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry. Drug Metab Dispos (2006) 1.26
Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis. Drug Metab Dispos (2005) 1.21
Rhein induces apoptosis through induction of endoplasmic reticulum stress and Ca2+-dependent mitochondrial death pathway in human nasopharyngeal carcinoma cells. Anticancer Res (2007) 1.15
San-Huang-Xie-Xin-Tang inhibits Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells. J Ethnopharmacol (2007) 1.05
Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts. Int J Cancer (2008) 1.03
Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway. Cancer Res (2006) 1.03
Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. Food Chem Toxicol (2006) 1.01
San-Huang-Xie-Xin-Tang attenuates inflammatory responses in lipopolysaccharide-exposed rat lungs. J Ethnopharmacol (2005) 1.00
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci (2003) 0.99
Evaluation of the anti-angiogenic effect of aloe-emodin. Cell Mol Life Sci (2006) 0.96
Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1). Naunyn Schmiedebergs Arch Pharmacol (2007) 0.95
San-Huang-Xie-Xin-Tang reduces lipopolysaccharides-induced hypotension and inflammatory mediators. J Ethnopharmacol (2005) 0.92
Metabolism of sennosides by human intestinal bacteria. Pharmacology (1988) 0.88
Morin sulphates/glucuronides enhance macrophage function in microgravity culture system. Eur J Clin Invest (2005) 0.86
Identification of three sulfate-conjugated metabolites of berberine chloride in healthy volunteers' urine after oral administration. Acta Pharmacol Sin (2002) 0.86
Relationship between phosphodiesterase inhibition induced by several Kampo medicines and smooth muscle relaxation of gastrointestinal tract tissues of rats. J Pharmacol Sci (2003) 0.85
The role of gastric muscle relaxation in cytoprotection induced by san-huang-xie-xin-tang in rats. J Ethnopharmacol (1994) 0.84
Effects of San'o-shashin-to on the antioxidative mechanism in spontaneous familial hypercholesterolaemic rabbits. Pharmacol Res (2000) 0.81
Two-year experience with "San-Huang-Hsieh-Hsin-Tang" in essential hypertension. Am J Chin Med (1986) 0.80
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Pharmacokinetic-metabolic studies with 14C-aloe emodin after oral administration to male and female rats. Pharmacology (1993) 0.77
Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. J Pharm Pharmacol (2003) 1.35
Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds. Antiviral Res (2005) 1.21
Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis. Drug Metab Dispos (2005) 1.21
Polymorphisms inside microRNAs and microRNA target sites predict clinical outcomes in prostate cancer patients receiving androgen-deprivation therapy. Clin Cancer Res (2010) 1.13
Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites. J Agric Food Chem (2009) 1.04
Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. Biol Pharm Bull (2003) 1.03
Genetic variants in microRNAs and microRNA target sites predict biochemical recurrence after radical prostatectomy in localized prostate cancer. Int J Cancer (2014) 0.99
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci (2003) 0.99
Antioxidant and anti-inflammatory potential of hesperetin metabolites obtained from hesperetin-administered rat serum: an ex vivo approach. J Agric Food Chem (2011) 0.95
Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors. Bioorg Med Chem Lett (2005) 0.93
Novel mutation of topoisomerase I in rendering cells resistant to camptothecin. Cancer Res (2002) 0.92
Generation of carcinoembryonic antigen (CEA)-specific T-cell responses in HLA-A*0201 and HLA-A*2402 late-stage colorectal cancer patients after vaccination with dendritic cells loaded with CEA peptides. Clin Cancer Res (2004) 0.92
Rhizomes of Gastrodia elata B(L) possess antidepressant-like effect via monoamine modulation in subchronic animal model. Am J Chin Med (2009) 0.90
Potential ex vivo immunomodulatory effects of San-Huang-Xie-Xin-Tang and its component herbs on mice and humans. J Ethnopharmacol (2009) 0.90
Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis. Planta Med (2004) 0.89
Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats. J Pharm Sci (2010) 0.88
The antioxidant effects of quercetin metabolites on the prevention of high glucose-induced apoptosis of human umbilical vein endothelial cells. Br J Nutr (2008) 0.87
Pharmacokinetic and pharmacodynamic interactions of morin and cyclosporin. Toxicol Appl Pharmacol (2005) 0.87
Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. Planta Med (2010) 0.86
Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats. Toxicol Appl Pharmacol (2005) 0.85
Steady-state pharmacokinetics and tissue distribution of anthraquinones of Rhei Rhizoma in rats. J Ethnopharmacol (2011) 0.85
Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4. J Agric Food Chem (2011) 0.85
Synthesis and antiproliferative evaluation of 3,5-disubstituted 1,2,4-triazoles containing flurophenyl and trifluoromethanephenyl moieties. Bioorg Med Chem Lett (2011) 0.85
Comparison of metabolic pharmacokinetics of naringin and naringenin in rabbits. Life Sci (2002) 0.84
Pharmacokinetics, bioavailability, and tissue distribution of magnolol following single and repeated dosing of magnolol to rats. Planta Med (2011) 0.84
A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats. Toxicol Appl Pharmacol (2012) 0.84
Lethal quercetin-digoxin interaction in pigs. Life Sci (2004) 0.84
Profound difference of metabolic pharmacokinetics between pure glycyrrhizin and glycyrrhizin in licorice decoction. Life Sci (2005) 0.83
Aloe-emodin suppressed NMDA-induced apoptosis of retinal ganglion cells through regulation of ERK phosphorylation. Phytother Res (2007) 0.83
Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. J Ethnopharmacol (2012) 0.83
Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats. Life Sci (2002) 0.83
Glycyrrhizin and licorice significantly affect the pharmacokinetics of methotrexate in rats. J Agric Food Chem (2009) 0.82
Degradation of flavonoid aglycones by rabbit, rat and human fecal flora. Biol Pharm Bull (2003) 0.82
Potential risk of mulberry-drug interaction: modulation on P-glycoprotein and cytochrome P450 3A. J Agric Food Chem (2013) 0.82
Vitamin D receptor gene variants and clinical outcomes after androgen-deprivation therapy for prostate cancer. World J Urol (2011) 0.81
Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: an ex vivo approach. J Ethnopharmacol (2010) 0.81
Genetic variants in nuclear factor-kappa B binding sites are associated with clinical outcomes in prostate cancer patients. Eur J Cancer (2013) 0.81
An ecdysone and tetracycline dual regulatory expression system for studies on Rac1 small GTPase-mediated signaling. Am J Physiol Cell Physiol (2003) 0.81
Mitochondria-mediated and p53-associated apoptosis induced in human cancer cells by a novel selenophene derivative, D-501036. Biochem Pharmacol (2006) 0.80
Concurrent delivery of tumor antigens and activation signals to dendritic cells by irradiated CD40 ligand-transfected tumor cells resulted in efficient activation of specific CD8+ T cells. Cancer Gene Ther (2004) 0.80
Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis. Evid Based Complement Alternat Med (2011) 0.80
Pharmacokinetics and Relative Bioavailability of Flavonoids between Two Dosage Forms of Gegen-Qinlian-Tang in Rats. Evid Based Complement Alternat Med (2012) 0.80
Ginger significantly decreased the oral bioavailability of cyclosporine in rats. Am J Chin Med (2006) 0.80
Liquorice reduced cyclosporine bioavailability by activating P-glycoprotein and CYP 3A. Food Chem (2012) 0.80
The antidepressant effect of Gastrodia elata Bl. on the forced-swimming test in rats. Am J Chin Med (2008) 0.79
A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Planta Med (2003) 0.79
A Chinese herb formula decreases the monocarboxylate transporter-mediated absorption of valproic acid in rats. Phytomedicine (2013) 0.79
Metabolism and pharmacokinetics of anthraquinones in Rheum palmatum in rats and ex vivo antioxidant activity. Planta Med (2009) 0.79
Hydrolysates of citrus plants stimulate melanogenesis protecting against UV-induced dermal damage. Phytother Res (2010) 0.78
Citrus grandis peel increases the bioavailability of cyclosporine and tacrolimus, two important immunosuppressants, in rats. J Med Food (2011) 0.77
Enhancing the bioavailability of magnolol in rabbits using melting solid dispersion with polyvinylpyrrolidone. Drug Dev Ind Pharm (2013) 0.77
Metabolic transformation of sesamol and ex vivo effect on 2,2'-azo-bis(2-amidinopropane)dihydrochloride-induced hemolysis. J Agric Food Chem (2008) 0.77
Different influences on tacrolimus pharmacokinetics by coadministrations of zhi ke and zhi shi in rats. Evid Based Complement Alternat Med (2011) 0.77
St. John's wort significantly increased the systemic exposure and toxicity of methotrexate in rats. Toxicol Appl Pharmacol (2012) 0.76