Published in PLoS Pathog on September 11, 2009
Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skin. Cell Host Microbe (2010) 3.78
Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens. J Virol (2010) 2.88
Why do viruses cause cancer? Highlights of the first century of human tumour virology. Nat Rev Cancer (2010) 2.68
Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients. Cancer Res (2010) 2.14
A cornucopia of human polyomaviruses. Nat Rev Microbiol (2013) 2.08
Novel polyomaviruses of nonhuman primates: genetic and serological predictors for the existence of multiple unknown polyomaviruses within the human population. PLoS Pathog (2013) 1.53
Merkel cell carcinoma: a virus-induced human cancer. Annu Rev Pathol (2011) 1.46
Detection of Merkel cell polyomavirus with a tumour-specific signature in non-small cell lung cancer. Br J Cancer (2013) 1.41
Generation of Merkel cell polyomavirus (MCV)-like particles and their application to detection of MCV antibodies. J Clin Microbiol (2010) 1.40
Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma. PLoS Pathog (2010) 1.40
Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood. Clin Cancer Res (2011) 1.36
Age-specific seroprevalence of Merkel cell polyomavirus, BK virus, and JC virus. Clin Vaccine Immunol (2011) 1.35
Merkel cell polyomavirus: a newly discovered human virus with oncogenic potential. Virology (2013) 1.27
Seroprevalence of trichodysplasia spinulosa-associated polyomavirus. Emerg Infect Dis (2011) 1.25
Cellular and viral factors regulating Merkel cell polyomavirus replication. PLoS One (2011) 1.21
Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry. PLoS Pathog (2011) 1.19
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis. J Invest Dermatol (2012) 1.14
MCV and Merkel cell carcinoma: a molecular success story. Curr Opin Virol (2012) 1.14
Papillomavirus infection requires gamma secretase. J Virol (2010) 1.12
Mucin biopolymers as broad-spectrum antiviral agents. Biomacromolecules (2012) 1.08
Viruses and human cancer: from detection to causality. Cancer Lett (2010) 1.05
Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor viruses. Int J Biol Sci (2010) 1.05
Immunological detection of viral large T antigen identifies a subset of Merkel cell carcinoma tumors with higher viral abundance and better clinical outcome. Int J Cancer (2010) 1.03
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The raccoon polyomavirus genome and tumor antigen transcription are stable and abundant in neuroglial tumors. J Virol (2014) 1.03
Activation of the PI3K/AKT pathway in Merkel cell carcinoma. PLoS One (2012) 1.02
The Merkel cell polyomavirus minor capsid protein. PLoS Pathog (2013) 1.01
Positive correlation between Merkel cell polyomavirus viral load and capsid-specific antibody titer. Med Microbiol Immunol (2011) 1.01
Structures of Merkel cell polyomavirus VP1 complexes define a sialic acid binding site required for infection. PLoS Pathog (2012) 1.01
Asymptomatic primary Merkel cell polyomavirus infection among adults. Emerg Infect Dis (2011) 0.99
Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome. PLoS One (2011) 0.98
Entry tropism of BK and Merkel cell polyomaviruses in cell culture. PLoS One (2012) 0.98
Human polyomaviruses in skin diseases. Patholog Res Int (2011) 0.98
Progressive multifocal leukoencephalopathy-associated mutations in the JC polyomavirus capsid disrupt lactoseries tetrasaccharide c binding. MBio (2013) 0.95
T-cell responses to oncogenic merkel cell polyomavirus proteins distinguish patients with merkel cell carcinoma from healthy donors. Clin Cancer Res (2014) 0.94
Characterization of monoclonal antibodies specific for the Merkel cell polyomavirus capsid. Virology (2010) 0.93
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The role of the immune response in merkel cell carcinoma. Cancers (Basel) (2013) 0.91
Mutational analysis of merkel cell carcinoma. Cancers (Basel) (2014) 0.90
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BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism. J Virol (2013) 0.88
T-helper cell-mediated proliferation and cytokine responses against recombinant Merkel cell polyomavirus-like particles. PLoS One (2011) 0.88
Neutralization serotyping of BK polyomavirus infection in kidney transplant recipients. PLoS Pathog (2012) 0.88
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Newly discovered KI, WU, and Merkel cell polyomaviruses: no evidence of mother-to-fetus transmission. Virol J (2010) 0.84
Frequent detection of Merkel cell polyomavirus DNA in sera of HIV-1-positive patients. Virol J (2013) 0.84
Pseudovirus mimics cell entry and trafficking of the human polyomavirus JCPyV. Virus Res (2013) 0.83
Merkel cell polyomavirus is not detected in mesotheliomas. J Clin Virol (2009) 0.83
Merkel cell carcinoma. Am J Clin Oncol (2013) 0.83
Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus DNAs and antibodies in blood among the elderly. BMC Infect Dis (2012) 0.81
Seroprevalence of Merkel cell polyomavirus in the general rural population of Anyang, China. PLoS One (2014) 0.81
Review on the relationship between human polyomaviruses-associated tumors and host immune system. Clin Dev Immunol (2012) 0.81
Trichodysplasia spinulosa-associated polyomavirus (TSV) and Merkel cell polyomavirus: correlation between humoral and cellular immunity stronger with TSV. PLoS One (2012) 0.81
Inflammatory cell distribution in primary merkel cell carcinoma. Cancers (Basel) (2014) 0.80
Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast. BMC Biotechnol (2015) 0.78
Characterization of self-assembled virus-like particles of Merkel cell polyomavirus. PLoS One (2015) 0.78
No evidence for the involvement of XMRV or MCV in the pathogenesis of breast cancer. Br J Cancer (2012) 0.78
The blood DNA virome in 8,000 humans. PLoS Pathog (2017) 0.78
Identification of the neutralizing epitopes of Merkel cell polyomavirus major capsid protein within the BC and EF surface loops. PLoS One (2015) 0.77
Manipulating gene expression and signaling activity in cultured mouse limb bud cells. Dev Dyn (2014) 0.77
DNA from KI, WU and Merkel cell polyomaviruses is not detected in childhood central nervous system tumours or neuroblastomas. PLoS One (2009) 0.76
Merkel cell polyomavirus and Merkel cell carcinoma. Philos Trans R Soc Lond B Biol Sci (2017) 0.76
Development of a lentivirus vector-based assay for non-destructive monitoring of cell fusion activity. PLoS One (2014) 0.75
Serological cross-reactivity between Merkel cell polyomavirus and two closely related chimpanzee polyomaviruses. PLoS One (2014) 0.75
Merkel cell polyomavirus infection and Merkel cell carcinoma. Curr Opin Virol (2016) 0.75
Characterization of human papillomavirus type 16 pseudovirus containing histones. BMC Biotechnol (2016) 0.75
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Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science (2008) 16.60
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Persistence of DNA sequences of BK virus and JC virus in normal human tissues and in diseased tissues. J Infect Dis (1983) 3.89
Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. J Med Virol (2003) 3.73
Frequent detection of Merkel cell polyomavirus in human Merkel cell carcinomas and identification of a unique deletion in the VP1 gene. Cancer Res (2008) 3.32
MC polyomavirus is frequently present in Merkel cell carcinoma of European patients. J Invest Dermatol (2008) 3.29
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Merkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors. J Invest Dermatol (2008) 2.80
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Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays. Int J Cancer (2009) 2.77
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A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology (2005) 2.60
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The role of polyomaviruses in human disease. Virology (2008) 2.41
Cross-neutralization of cutaneous and mucosal Papillomavirus types with anti-sera to the amino terminus of L2. Virology (2005) 2.31
Reactivation and mutation of newly discovered WU, KI, and Merkel cell carcinoma polyomaviruses in immunosuppressed individuals. J Infect Dis (2009) 2.28
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Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue. BMC Cell Biol (2008) 1.75
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Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathy. J Virol (2006) 1.58
Merkel cell polyomavirus in cutaneous squamous cell carcinoma of immunocompetent individuals. J Invest Dermatol (2009) 1.53
Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Int J Cancer (2009) 1.49
Merkel cell polyomavirus in respiratory tract secretions. Emerg Infect Dis (2009) 1.49
Prevalence of Merkel cell polyomavirus in Merkel cell carcinoma. Mod Pathol (2009) 1.41
Merkel cell polyomavirus DNA in respiratory specimens from children and adults. Emerg Infect Dis (2009) 1.39
The SV40 pseudovirus: its potential for general transduction in animal cells. Proc Natl Acad Sci U S A (1970) 1.23
Immunoglobulin G, A, and M responses to BK virus in renal transplantation. Clin Vaccine Immunol (2006) 1.12
longitudinal analysis of levels of immunoglobulins against BK virus capsid proteins in kidney transplant recipients. Clin Vaccine Immunol (2008) 1.09
Merkel cell polyomavirus strains in patients with merkel cell carcinoma. Emerg Infect Dis (2009) 1.05
Serological diagnosis of human polyomavirus infection. Adv Exp Med Biol (2006) 1.05
Getting stronger: the relationship between a newly identified virus and Merkel cell carcinoma. J Invest Dermatol (2009) 1.01
Merkel cell carcinoma. Cell Mol Life Sci (2009) 1.01
No excess risk for colorectal cancer among subjects seropositive for the JC polyomavirus. Int J Cancer (2007) 0.99
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA. Mol Cell Biol (2006) 0.94
SV40 vectors carrying minimal sequence of viral origin with exchangeable capsids. Virology (2008) 0.88
Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science (2008) 16.60
Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med (2012) 11.72
T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc Natl Acad Sci U S A (2008) 4.74
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Germline mutations in BAP1 predispose to melanocytic tumors. Nat Genet (2011) 3.91
Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan. Nat Med (2007) 3.88
Reactivity of human sera in a sensitive, high-throughput pseudovirus-based papillomavirus neutralization assay for HPV16 and HPV18. Virology (2004) 3.85
Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skin. Cell Host Microbe (2010) 3.78
MC polyomavirus is frequently present in Merkel cell carcinoma of European patients. J Invest Dermatol (2008) 3.29
Antibody targeted drugs as cancer therapeutics. Nat Rev Drug Discov (2006) 3.08
Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis. J Carcinog (2004) 3.02
Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens. J Virol (2010) 2.88
Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors. Int J Cancer (2009) 2.78
Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays. Int J Cancer (2009) 2.77
Why do viruses cause cancer? Highlights of the first century of human tumour virology. Nat Rev Cancer (2010) 2.68
Human transcriptome subtraction by using short sequence tags to search for tumor viruses in conjunctival carcinoma. J Virol (2007) 2.68
A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth. Nat Med (2002) 2.55
Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator. J Clin Invest (2011) 2.37
A protective and broadly cross-neutralizing epitope of human papillomavirus L2. J Virol (2007) 2.36
Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T-cell lymphoma. J Clin Oncol (2010) 2.33
Cross-neutralization of cutaneous and mucosal Papillomavirus types with anti-sera to the amino terminus of L2. Virology (2005) 2.31
Kaposi's sarcoma-associated herpesvirus immunoevasion and tumorigenesis: two sides of the same coin? Annu Rev Microbiol (2003) 2.07
Neutralization of human papillomavirus with monoclonal antibodies reveals different mechanisms of inhibition. J Virol (2007) 2.05
Taxonomical developments in the family Polyomaviridae. Arch Virol (2011) 2.03
Viral IL-6-induced cell proliferation and immune evasion of interferon activity. Science (2002) 1.97
Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol (2007) 1.87
A sensitive non-radioactive northern blot method to detect small RNAs. Nucleic Acids Res (2010) 1.81
Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas. Am J Surg Pathol (2009) 1.79
Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. Nucleic Acids Res (2012) 1.66
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS One (2007) 1.65
Survivin is a therapeutic target in Merkel cell carcinoma. Sci Transl Med (2012) 1.61
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Identification of novel survivin-derived CTL epitopes. Cancer Biol Ther (2004) 1.56
Role of matrix metalloproteinases in melanoma cell invasion. Biochimie (2005) 1.54
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The universal character of the tumor-associated antigen survivin. Clin Cancer Res (2007) 1.50
An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells. Int J Cancer (2011) 1.49
Anti-cancer therapies targeting the tumor stroma. Cancer Immunol Immunother (2007) 1.49
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Merkel cell carcinoma: a virus-induced human cancer. Annu Rev Pathol (2011) 1.46
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The etiology and epidemiology of merkel cell carcinoma. Curr Probl Cancer (2010) 1.39
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Merkel cell polyomavirus large T antigen disrupts host genomic integrity and inhibits cellular proliferation. J Virol (2013) 1.28
Temozolomide in combination with interferon-alfa versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, phase III, multicenter study from the Dermatologic Cooperative Oncology Group. J Clin Oncol (2005) 1.27
Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7. Cell Host Microbe (2013) 1.27
Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers. Surgery (2006) 1.25
Macrophage migration inhibitory factor contributes to the immune escape of ovarian cancer by down-regulating NKG2D. J Immunol (2008) 1.23
Characterization of viral and human RNAs smaller than canonical MicroRNAs. J Virol (2009) 1.23
Regulators of apoptosis: suitable targets for immune therapy of cancer. Nat Rev Drug Discov (2005) 1.22
Cellular and viral factors regulating Merkel cell polyomavirus replication. PLoS One (2011) 1.21
Use of a multiantigen detection algorithm for diagnosis of Kaposi's sarcoma-associated herpesvirus infection. J Clin Microbiol (2006) 1.21
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Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry. PLoS Pathog (2011) 1.19
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts preferentially with the terminal repeats of the genome in vivo and this complex is sufficient for episomal DNA replication. J Gen Virol (2003) 1.17
Multicolor microRNA FISH effectively differentiates tumor types. J Clin Invest (2013) 1.16
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation. Cancer Res (2003) 1.14
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Chromosomal alterations detected by comparative genomic hybridization in nonfunctioning endocrine pancreatic tumors. Cancer Genet Cytogenet (2005) 1.14
IGFBP7 is not required for B-RAF-induced melanocyte senescence. Cell (2010) 1.13
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High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays. PLoS One (2011) 1.11
Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication. PLoS Pathog (2012) 1.11
CD147 impacts angiogenesis and metastasis formation. Cancer Invest (2009) 1.11
Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation. Virchows Arch (2006) 1.09
Coupled transcriptome and proteome analysis of human lymphotropic tumor viruses: insights on the detection and discovery of viral genes. BMC Genomics (2011) 1.09
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Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells. Mol Carcinog (2003) 1.07