Asthma: epidemiology, etiology and risk factors.

PubWeight™: 1.82‹?› | Rank: Top 3%

🔗 View Article (PMC 2764772)

Published in CMAJ on September 14, 2009

Authors

Padmaja Subbarao1, Piush J Mandhane, Malcolm R Sears

Author Affiliations

1: Department of Pediatric Respirology, Hospital for Sick Children, University of Toronto, Toronto, Ont.

Articles citing this

Prevalence of asthma and other allergic conditions in Colombia 2009-2010: a cross-sectional study. BMC Pulm Med (2012) 1.01

Pulmonary toxicity and adjuvant effect of di-(2-exylhexyl) phthalate in ovalbumin-immunized BALB/c mice. PLoS One (2012) 0.96

Epidemiologic methods of assessing asthma and wheezing episodes in longitudinal studies: measures of change and stability. J Epidemiol (2013) 0.96

Risk of childhood asthma following infant bronchiolitis during the respiratory syncytial virus season. J Allergy Clin Immunol (2013) 0.94

A comparison of three methods to measure asthma in epidemiologic studies: results from the Danish National Birth Cohort. PLoS One (2012) 0.94

Asthma prevalence associated with geographical latitude and regional insolation in the United States of America and Australia. PLoS One (2011) 0.94

Changing Trends in Asthma Prevalence Among Children. Pediatrics (2015) 0.89

Genomic and non-genomic actions of glucocorticoids in asthma. Ann Thorac Med (2010) 0.89

Pediatric Drug Safety Surveillance in FDA-AERS: A Description of Adverse Events from GRiP Project. PLoS One (2015) 0.88

Work-Related Asthma in Korea - Findings from the Korea Work-Related Asthma Surveillance (KOWAS) program, 2004-2009. Allergy Asthma Immunol Res (2014) 0.87

Change in prevalence of chronic conditions between childhood and adolescence among extremely low-birth-weight children. JAMA (2011) 0.87

Childhood asthma and physical activity: a systematic review with meta-analysis and Graphic Appraisal Tool for Epidemiology assessment. BMC Pediatr (2016) 0.86

Unexpected course of nonlinear cardiac interbeat interval dynamics during childhood and adolescence. PLoS One (2011) 0.85

SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice. Am J Respir Cell Mol Biol (2012) 0.85

Asthma, type 1 and type 2 diabetes mellitus, and inflammatory bowel disease amongst South Asian immigrants to Canada and their children: a population-based cohort study. PLoS One (2015) 0.84

Breastfeeding is associated with reduced childhood hospitalization: evidence from a Scottish Birth Cohort (1997-2009). J Pediatr (2014) 0.84

Overexpression of microRNA-21 and microRNA-126 in the patients of bronchial asthma. Int J Clin Exp Med (2014) 0.84

A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res (2011) 0.84

CO(2) concentration in day care centres is related to wheezing in attending children. Eur J Pediatr (2014) 0.84

Asthma in children born after infertility treatment: findings from the UK Millennium Cohort Study. Hum Reprod (2012) 0.82

Mining and Visualizing Family History Associations in the Electronic Health Record: A Case Study for Pediatric Asthma. AMIA Annu Symp Proc (2015) 0.82

Asthma and allergies in Jamaican children aged 2-17 years: a cross-sectional prevalence survey. BMJ Open (2012) 0.82

Exploring the Determinants of the Perceived Risk of Food Allergies in Canada. Hum Ecol Risk Assess (2012) 0.81

Prevalence of asthma symptoms in schoolchildren, and climate in west European countries: an ecologic study. Int J Biometeorol (2012) 0.81

Predictors of interleukin-33 and thymic stromal lymphopoietin levels in cord blood. Pediatr Allergy Immunol (2015) 0.80

Corticosteroids in the treatment of acute asthma. Ann Thorac Med (2014) 0.79

Social inequalities in wheezing in children: findings from the UK Millennium Cohort Study. Eur Respir J (2015) 0.79

Allergic asthma biomarkers using systems approaches. Front Genet (2014) 0.79

Ten years of asthma admissions to adult critical care units in England and Wales. BMJ Open (2013) 0.79

Semistructured black-box prediction: proposed approach for asthma admissions in London. Int J Gen Med (2012) 0.79

Role of thrombin-activatable fibrinolysis inhibitor in allergic bronchial asthma. Lung (2011) 0.78

The effect of sand storms on acute asthma in Riyadh, Saudi Arabia. Ann Thorac Med (2015) 0.78

Aldose reductase inhibition suppresses airway inflammation. Chem Biol Interact (2011) 0.77

Maternal socioeconomic status and the risk of asthma among offspring. BMC Public Health (2015) 0.77

Severe and Moderate Asthma Exacerbations in Asthmatic Children and Exposure to Ambient Air Pollutants. Int J Environ Res Public Health (2016) 0.76

Association between traffic-related air pollution and asthma in preschool children in a national Japanese nested case-control study. BMJ Open (2016) 0.76

Asthma and the microbiome: defining the critical window in early life. Allergy Asthma Clin Immunol (2017) 0.75

Acetaminophen and asthma. CMAJ (2009) 0.75

The recurrence risk of genetic complex diseases. J Res Med Sci (2017) 0.75

Helicobacter pylori and allergy: Update of research. World J Methodol (2015) 0.75

Machine learning approaches to personalize early prediction of asthma exacerbations. Ann N Y Acad Sci (2016) 0.75

Asthma associations in children attending a museum of science. Int J Environ Res Public Health (2013) 0.75

Reference Values and Utility of Serum Total Immunoglobulin E for Predicting Atopy and Allergic Diseases in Korean Schoolchildren. J Korean Med Sci (2017) 0.75

Prevalence of Asthma and Respiratory Symptoms among University Students in Sari (North of Iran). Tanaffos (2016) 0.75

Anxiety mediates the effect of smoking on insomnia in people with asthma: evidence from the HUNT3 study. J Multidiscip Healthc (2016) 0.75

Parental smoking and cessation during pregnancy and the risk of childhood asthma. BMC Public Health (2016) 0.75

Effect of Relocation to the U.S. on Asthma Risk Among Hispanics. Am J Prev Med (2017) 0.75

Effects of the combined extracts of Herba Epimedii and Fructus Ligustrilucidi on airway remodeling in the asthmatic rats with the treatment of budesonide. BMC Complement Altern Med (2017) 0.75

Articles cited by this

(truncated to the top 100)

Prevalence, natural history, and relationship of wheezy bronchitis and asthma in children. An epidemiological study. Br Med J (1969) 17.66

Hay fever, hygiene, and household size. BMJ (1989) 15.94

Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med (1995) 15.68

Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A (2005) 15.46

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43

Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet (1998) 12.26

Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet (2006) 12.04

The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med (2002) 9.26

The asthma epidemic. N Engl J Med (2006) 8.60

Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet (1999) 7.90

A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med (2003) 7.03

A national study of asthma in childhood. J Epidemiol Community Health (1978) 6.55

Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med (1999) 6.21

Rhinovirus illnesses during infancy predict subsequent childhood wheezing. J Allergy Clin Immunol (2005) 5.12

Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: a longitudinal study. Lancet (2002) 4.89

Asthma: defining of the persistent adult phenotypes. Lancet (2006) 4.78

Respiratory effects of exposure to diesel traffic in persons with asthma. N Engl J Med (2007) 4.58

Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med (2004) 4.32

Asthma genetics 2006: the long and winding road to gene discovery. Genes Immun (2006) 4.14

Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr (2007) 3.89

The prevalence and incidence of asthma and asthma-like symptoms in a general population sample. Am Rev Respir Dis (1980) 3.85

Gender differences in airway behaviour over the human life span. Thorax (1999) 3.52

Childhood asthma and poverty: differential impacts and utilization of health services. Pediatrics (1993) 3.42

Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr (2007) 3.40

Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N Engl J Med (1991) 3.36

Does the sibling effect have its origin in utero? Investigating birth order, cord blood immunoglobulin E concentration, and allergic sensitization at age 4 years. Am J Epidemiol (2001) 3.26

Community outbreaks of asthma associated with inhalation of soybean dust. Toxicoepidemiological Committee. N Engl J Med (1989) 3.16

Prevalence of asthma and atopy in two areas of West and East Germany. Am J Respir Crit Care Med (1994) 3.16

Increased risk of childhood asthma from antibiotic use in early life. Chest (2007) 3.11

Rates of admission to hospital for asthma. BMJ (1994) 2.87

Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study. Lancet (2006) 2.81

Asthma in schoolchildren. Demographic associations and peak expiratory flow rates compared in children with bronchitis. Br J Prev Soc Med (1975) 2.77

A national survey of asthma prevalence, severity, and treatment in Great Britain. Arch Dis Child (1994) 2.74

Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II). Lancet (2007) 2.74

Effects of marijuana smoking on pulmonary function and respiratory complications: a systematic review. Arch Intern Med (2007) 2.38

The European Community Respiratory Health Survey: what are the main results so far? European Community Respiratory Health Survey II. Eur Respir J (2001) 2.35

The relative risks of sensitivity to grass pollen, house dust mite and cat dander in the development of childhood asthma. Clin Exp Allergy (1989) 2.33

Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants. Lancet (1996) 2.33

Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking. Am J Respir Crit Care Med (2004) 2.27

The importance of prenatal exposures on the development of allergic disease: a birth cohort study using the West Midlands General Practice Database. Am J Respir Crit Care Med (2002) 2.22

ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med (2008) 2.18

The influence of age and sex on asthma admissions. JAMA (1993) 2.12

Chronic caregiver stress and IgE expression, allergen-induced proliferation, and cytokine profiles in a birth cohort predisposed to atopy. J Allergy Clin Immunol (2004) 2.11

Association between antenatal cytokine production and the development of atopy and asthma at age 6 years. Lancet (2003) 2.09

The Melbourne Asthma Study: 1964-1999. J Allergy Clin Immunol (2002) 2.07

Effect of early vs late intervention with inhaled corticosteroids in asthma. Chest (1995) 2.06

Parental stress as a predictor of wheezing in infancy: a prospective birth-cohort study. Am J Respir Crit Care Med (2002) 2.02

Race, socioeconomic factors, and area of residence are associated with asthma prevalence. Pediatr Pulmonol (1999) 2.01

The impact of stress on the development and expression of atopy. Curr Opin Allergy Clin Immunol (2005) 2.01

Menopause, postmenopausal estrogen preparations, and the risk of adult-onset asthma. A prospective cohort study. Am J Respir Crit Care Med (1995) 2.00

Mode of delivery and asthma -- is there a connection? Pediatr Res (2002) 1.99

Breast-feeding reduces the risk of asthma during the first 4 years of life. J Allergy Clin Immunol (2004) 1.95

The many faces of the hygiene hypothesis. J Allergy Clin Immunol (2006) 1.94

Socioeconomic factors and asthma hospitalization rates in New York City. J Asthma (1999) 1.92

Role of viral infections in the inception of asthma and allergies during childhood: could they be protective? Thorax (1994) 1.92

Role of microbial burden in aetiology of allergy and asthma. Lancet (1999) 1.92

Onset and persistence of childhood asthma: predictors from infancy. Pediatrics (2001) 1.91

Atopy in childhood. I. Gender and allergen related risks for development of hay fever and asthma. Clin Exp Allergy (1993) 1.90

Breast-feeding and the risk of bronchial asthma in childhood: a systematic review with meta-analysis of prospective studies. J Pediatr (2001) 1.89

The effects of race/ethnicity and income on early childhood asthma prevalence and health care use. Am J Public Health (2000) 1.88

Prospective study of risk factors for early and persistent wheezing in childhood. Eur Respir J (1995) 1.88

Breastfeeding duration is a risk factor for atopic eczema. Clin Exp Allergy (2002) 1.84

Exposure to furry pets and the risk of asthma and allergic rhinitis: a meta-analysis. Allergy (2008) 1.83

Bidirectional interactions between viral respiratory illnesses and cytokine responses in the first year of life. J Allergy Clin Immunol (2005) 1.81

The Canadian Childhood Asthma Primary Prevention Study: outcomes at 7 years of age. J Allergy Clin Immunol (2005) 1.80

Reduced lung function at birth and the risk of asthma at 10 years of age. N Engl J Med (2006) 1.79

Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. Am J Respir Crit Care Med (2004) 1.76

A longitudinal study of the effects of tobacco and cannabis exposure on lung function in young adults. Addiction (2002) 1.75

House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. J Allergy Clin Immunol (2001) 1.73

Differences in incidence of reported asthma related to age in men and women. A retrospective analysis of the data of the European Respiratory Health Survey. Am J Respir Crit Care Med (2000) 1.66

Wheeze phenotypes and lung function in preschool children. Am J Respir Crit Care Med (2004) 1.66

A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J Allergy Clin Immunol (2008) 1.65

Family history as a predictor of asthma risk. Am J Prev Med (2003) 1.62

Socioeconomic status and indicators of asthma in children. Am J Respir Crit Care Med (1995) 1.61

Incidence and outcomes of asthma in the elderly. A population-based study in Rochester, Minnesota. Chest (1997) 1.60

Study of the aetiology of wheezing illness at age 16 in two national British birth cohorts. Thorax (1996) 1.59

Longitudinal changes in allergen skin test reactivity in a community population sample. J Allergy Clin Immunol (1987) 1.59

The relationship between infant airway function, childhood airway responsiveness, and asthma. Am J Respir Crit Care Med (2004) 1.58

Area of residence, birthplace, and asthma in Puerto Rican children. Chest (2007) 1.58

Impaired airway function and wheezing in infancy: the influence of maternal smoking and a genetic predisposition to asthma. Am J Respir Crit Care Med (1999) 1.55

Influence of parental smoking on respiratory symptoms during the first decade of life: the Tucson Children's Respiratory Study. Am J Epidemiol (1999) 1.55

Is bronchial hyperresponsiveness more frequent in women than in men? A population-based study. Am J Respir Crit Care Med (1997) 1.54

The lung health study: airway responsiveness to inhaled methacholine in smokers with mild to moderate airflow limitation. The Lung Health Study Research Group. Am Rev Respir Dis (1992) 1.53

Outcome of wheeze in childhood. Symptoms and pulmonary function 25 years later. Am J Respir Crit Care Med (1994) 1.51

Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Am J Respir Crit Care Med (2006) 1.51

Regular smoking and asthma incidence in adolescents. Am J Respir Crit Care Med (2006) 1.49

Asthma exacerbations . 1: epidemiology. Thorax (2006) 1.48

Antenatal determinants of neonatal immune responses to allergens. Clin Exp Allergy (2002) 1.47

Incidence and remission of asthma: a retrospective study on the natural history of asthma in Italy. J Allergy Clin Immunol (2002) 1.46

Inflammatory and structural changes in the small airways in bronchial asthma. Am J Respir Crit Care Med (1998) 1.46

Occupational airborne exposure and the incidence of respiratory symptoms and asthma. Am J Respir Crit Care Med (2002) 1.46

Income level and asthma prevalence and care patterns. Am J Respir Crit Care Med (1997) 1.44

The interrelationship among allergy, airways responsiveness, and asthma. J Asthma (1993) 1.44

Gender difference in airway hyperresponsiveness in smokers with mild COPD. The Lung Health Study. Am J Respir Crit Care Med (1994) 1.42

Parental and neonatal risk factors for atopy, airway hyper-responsiveness, and asthma. Arch Dis Child (1996) 1.41

A prospective study of the natural history of asthma. Remission and relapse rates. Chest (1986) 1.40

Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr (2006) 1.38

Influence of dog ownership and high endotoxin on wheezing and atopy during infancy. J Allergy Clin Immunol (2006) 1.36

The effects of respiratory infections, atopy, and breastfeeding on childhood asthma. Eur Respir J (2002) 1.35

Obesity: insight into the origins of asthma. Nat Immunol (2005) 1.33

Articles by these authors

An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38

A gradient of childhood self-control predicts health, wealth, and public safety. Proc Natl Acad Sci U S A (2011) 8.57

Association between children's experience of socioeconomic disadvantage and adult health: a life-course study. Lancet (2002) 5.32

Female and male antisocial trajectories: from childhood origins to adult outcomes. Dev Psychopathol (2008) 3.07

The safety of long-acting beta-agonists among patients with asthma using inhaled corticosteroids: systematic review and metaanalysis. Am J Respir Crit Care Med (2008) 3.01

The September epidemic of asthma exacerbations in children: a search for etiology. J Allergy Clin Immunol (2005) 2.87

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. CMAJ (2013) 2.39

Risk factors for airway remodeling in asthma manifested by a low postbronchodilator FEV1/vital capacity ratio: a longitudinal population study from childhood to adulthood. Am J Respir Crit Care Med (2002) 2.33

Cats and dogs and the risk of atopy in childhood and adulthood. J Allergy Clin Immunol (2009) 2.25

Prediction of differential adult health burden by conduct problem subtypes in males. Arch Gen Psychiatry (2007) 2.25

Relation between income, air pollution and mortality: a cohort study. CMAJ (2003) 2.07

Attenuation of the September epidemic of asthma exacerbations in children: a randomized, controlled trial of montelukast added to usual therapy. Pediatrics (2007) 1.80

A cohort study of traffic-related air pollution and mortality in Toronto, Ontario, Canada. Environ Health Perspect (2009) 1.77

Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. Am J Respir Crit Care Med (2004) 1.76

A longitudinal study of the effects of tobacco and cannabis exposure on lung function in young adults. Addiction (2002) 1.75

Leptin, adiponectin, and asthma: findings from a population-based cohort study. Ann Allergy Asthma Immunol (2009) 1.71

Traffic air pollution and mortality rate advancement periods. Am J Epidemiol (2004) 1.56

Is chronic asthma associated with shorter leukocyte telomere length at midlife? Am J Respir Crit Care Med (2014) 1.55

The September epidemic of asthma hospitalization: school children as disease vectors. J Allergy Clin Immunol (2006) 1.48

Overall asthma control: the relationship between current control and future risk. J Allergy Clin Immunol (2010) 1.41

The Ontario Asthma Regional Variation Study: emergency department visit rates and the relation to hospitalization rates. Chest (2006) 1.38

Risk factors for hospital admission for asthma from childhood to young adulthood: a longitudinal population study. J Allergy Clin Immunol (2002) 1.31

Environmental inequality and circulatory disease mortality gradients. J Epidemiol Community Health (2005) 1.28

Geographic and gender variability in the prevalence of bronchial responsiveness in Canada. Chest (2004) 1.26

Sex differences in factors associated with childhood- and adolescent-onset wheeze. Am J Respir Crit Care Med (2005) 1.26

Systemic inflammation and lung function in young adults. Thorax (2007) 1.23

Adiposity, asthma, and airway inflammation. J Allergy Clin Immunol (2006) 1.22

Cigarette smoking and allergic sensitization: a 32-year population-based cohort study. J Allergy Clin Immunol (2007) 1.15

Gut microbiota diversity and atopic disease: does breast-feeding play a role? J Allergy Clin Immunol (2012) 1.10

Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohort. Respir Res (2006) 1.09

Factors affecting exhaled nitric oxide measurements: the effect of sex. Respir Res (2007) 1.05

Spatial analysis of air pollution and childhood asthma in Hamilton, Canada: comparing exposure methods in sensitive subgroups. Environ Health (2009) 1.02

Variations and gaps in management of acute asthma in Ontario emergency departments. Chest (2008) 0.97

Changes in exhaled nitric oxide related to estrogen and progesterone during the menstrual cycle. Chest (2009) 0.96

Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fixed dosing: a five-month multicentre Canadian study. Can Respir J (2003) 0.95

Trends in the prevalence of asthma. Chest (2014) 0.93

Exposure assessment in cohort studies of childhood asthma. Environ Health Perspect (2010) 0.92

Canadian economic evaluation of budesonide-formoterol as maintenance and reliever treatment in patients with moderate to severe asthma. Can Respir J (2007) 0.92

Overall asthma control achieved with budesonide/formoterol maintenance and reliever therapy for patients on different treatment steps. Respir Res (2011) 0.91

Prevalence of asthma among Chinese adolescents living in Canada and in China. CMAJ (2008) 0.91

The association between chronic exposure to traffic-related air pollution and ischemic heart disease. J Toxicol Environ Health A (2012) 0.91

Outcome in adulthood of asymptomatic airway hyperresponsiveness in childhood: a longitudinal population study. Pediatr Pulmonol (2002) 0.89

Breastfeeding and allergies: time for a change in paradigm? Curr Opin Allergy Clin Immunol (2008) 0.89

Epidemiology of asthma: risk factors for development. Expert Rev Clin Immunol (2009) 0.88

Airflow obstruction in young adults in Canada. Can Respir J (2007) 0.86

Interactions between breast-feeding, specific parental atopy, and sex on development of asthma and atopy. J Allergy Clin Immunol (2007) 0.86

Inhaled corticosteroids for asthma: common clinical quandaries. J Asthma (2003) 0.86

Asthma in remission: can relapse in early adulthood be predicted at 18 years of age? Chest (2005) 0.84

Disparate geographic prevalences of asthma, allergic rhinoconjunctivitis and atopic eczema among adolescents in five Canadian cities. Pediatr Allergy Immunol (2010) 0.84

The safety of formoterol among patients with asthma using inhaled corticosteroids. Systematic review and meta-analysis. Pol Arch Med Wewn (2008) 0.84

Budesonide/formoterol maintenance and reliever therapy versus conventional best practice. Respir Med (2009) 0.82

Perinatal antibiotic exposure of neonates in Canada and associated risk factors: a population-based study. J Matern Fetal Neonatal Med (2014) 0.82

Links between anxiety and allergies: psychobiological reality or possible methodological bias? J Pers (2009) 0.81

The safety of long-acting beta-agonists: more evidence is needed. Respirology (2010) 0.81

Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms. Hum Genet (2009) 0.80

Association between exhaled nitric oxide and systemic inflammatory markers. Ann Allergy Asthma Immunol (2007) 0.80

Step-up therapy in uncontrolled asthma: choices and outcomes. J Allergy Clin Immunol (2008) 0.79

Mortality among subjects with chronic obstructive pulmonary disease or asthma at two respiratory disease clinics in Ontario. Can Respir J (2011) 0.78

The Back to School asthma study: the effect of montelukast on asthma burden when initiated prophylactically at the start of the school year. Ann Allergy Asthma Immunol (2010) 0.78

Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study. Environ Health Perspect (2015) 0.78

Relevance of birth cohorts to assessment of asthma persistence. Curr Allergy Asthma Rep (2012) 0.78

Association between exhaled nitric oxide and systemic inflammatory markers. Ann Allergy Asthma Immunol (2007) 0.78

The association between community stressors and asthma prevalence of school children in Winnipeg, Canada. Int J Environ Res Public Health (2012) 0.77

The prevalence of asthma in Canadian children of South Asian descent. Pediatr Pulmonol (2013) 0.76

Predicting new and persistent asthma. Am J Respir Crit Care Med (2012) 0.76

A new exposure metric for traffic-related air pollution? An analysis of determinants of hopanes in settled indoor house dust. Environ Health (2013) 0.76

Full-night versus 4h evening polysomnography in children less than 2years of age. Sleep Med (2012) 0.76

The potential to predict the course of childhood asthma. Expert Rev Respir Med (2014) 0.75

The chicken or the egg? Perhaps the egg. Arch Dis Child (2008) 0.75

Long-acting bronchodilators in COPD. Chest (2008) 0.75

The Salmeterol Multicenter Asthma Research Trial. Chest (2006) 0.75

Asthma mortality in southern Brazil: is there a changing trend? J Asthma (2007) 0.75

Prevalence and correlates of a 'knee' pattern on the maximal expiratory flow-volume loop in young adults. Respirology (2014) 0.75

Three-dimensional modeled custom-made noninvasive positive pressure ventilation masks in an infant. Am J Respir Crit Care Med (2014) 0.75