Published in Res Commun Chem Pathol Pharmacol on July 01, 1977
Disulfiram inhibition of the alternative respiratory pathway in plant mitochondria. Plant Physiol (1981) 1.59
Disulfiram metabolite S-methyl-N,N-diethylthiocarbamate quantitation in human plasma with reverse phase ultra performance liquid chromatography and mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.77
Chlorpyrifos: pharmacokinetics in human volunteers. Toxicol Appl Pharmacol (1984) 3.34
Childhood tuberculosis in North Carolina: a study of the opportunities for intervention in the transmission of tuberculosis to children. Am J Public Health (1986) 1.86
A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans. Toxicol Sci (2002) 1.50
Inhibition of pepsin by zymogen activation fragments. Spectrum of peptides released from pepsinogen NH2 terminus and solid phase synthesis of two inhibitory peptide sequences. J Biol Chem (1978) 1.24
Biological effects of short-term, high-concentration exposure to methyl isocyanate. I. Study objectives and inhalation exposure design. Environ Health Perspect (1987) 1.16
Acute inhalation studies with methyl isocyanate vapor. II. Respiratory tract changes in guinea pigs, rats, and mice. Fundam Appl Toxicol (1986) 1.13
Biological effects of short-term, high-concentration exposure to methyl isocyanate. II. Blood chemistry and hematologic evaluations. Environ Health Perspect (1987) 1.11
Elimination kinetics of disulfiram in alcoholics after single and repeated doses. Clin Pharmacol Ther (1984) 1.11
Biological effects of short-term, high-concentration exposure to methyl isocyanate. III. Influence on gas exchange in the guinea pig lung. Environ Health Perspect (1987) 1.09
Biological effects of short-term, high-concentration exposure to methyl isocyanate. V. Morphologic evaluation of rat and guinea pig lungs. Environ Health Perspect (1987) 1.08
Ethylene glycol monobutyl ether: acute, 9-day, and 90-day vapor inhalation studies in Fischer 344 rats. Toxicol Appl Pharmacol (1983) 1.06
Respiratory tract changes in guinea pigs, rats, and mice following a single six-hour exposure to methyl isocyanate vapor. Environ Health Perspect (1987) 1.06
Acute inhalation studies with methyl isocyanate vapor. I. Methodology and LC50 determinations in guinea pigs, rats, and mice. Fundam Appl Toxicol (1986) 1.03
Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram. Drug Metab Dispos (1995) 1.03
Methyl isocyanate subchronic vapor inhalation studies with Fischer 344 rats. Fundam Appl Toxicol (1986) 1.02
Carbamoylation of brain glutamate receptors by a disulfiram metabolite. J Biol Chem (1997) 0.99
In vitro and in vivo inhibition of rat liver aldehyde dehydrogenase by S-methyl N,N-diethylthiolcarbamate sulfoxide, a new metabolite of disulfiram. Biochem Pharmacol (1992) 0.98
Role of taurine in regulation of intracellular calcium level and neuroprotective function in cultured neurons. J Neurosci Res (2001) 0.97
Biological effects of short-term, high-concentration exposure to methyl isocyanate. VI. In vitro and in vivo complement activation studies. Environ Health Perspect (1987) 0.95
Methyl isocyanate eight-day vapor inhalation study with Fischer 344 rats. Environ Health Perspect (1987) 0.95
A68930: a potent agonist selective for the dopamine D1 receptor. Eur J Pharmacol (1991) 0.94
Eighty-five day postexposure follow-up study in Fischer 344 rats after repeated exposures to methyl isocyanate vapor. Environ Health Perspect (1987) 0.91
The acute toxicity and primary irritancy of N-benzyl-N,N-dimethylamine. Drug Chem Toxicol (1985) 0.91
Comparative aspects of disulfiram and its metabolites in the disulfiram-ethanol reaction in the rat. Biochem Pharmacol (1989) 0.90
Distribution of S35 disulfiram and metabolites in mice, and metabolism of S35 disulfiram in the dog. Res Commun Chem Pathol Pharmacol (1978) 0.89
Human red blood cell acetylcholinesterase inhibition as the appropriate and conservative surrogate endpoint for establishing chlorpyrifos reference dose. Regul Toxicol Pharmacol (1999) 0.88
Lack of differential sensitivity to cholinesterase inhibition in fetuses and neonates compared to dams treated perinatally with chlorpyrifos. Toxicol Sci (2000) 0.87
Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate. Biochem Pharmacol (1993) 0.87
Disulfiram metabolism as a requirement for the inhibition of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol (1991) 0.87
A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate. Toxicol Sci (2000) 0.86
In vivo pharmacodynamic studies of the disulfiram metabolite S-methyl N,N-diethylthiolcarbamate sulfoxide: inhibition of liver aldehyde dehydrogenase. Alcohol Clin Exp Res (1994) 0.85
In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human. Arch Toxicol (1993) 0.85
Disulfiram distribution and elimination in the rat after oral and intraperitoneal administration. Alcohol Clin Exp Res (1980) 0.84
Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans. Toxicol Appl Pharmacol (1991) 0.83
Bioactivation of S-methyl N,N-diethylthiolcarbamate to S-methyl N,N-diethylthiolcarbamate sulfoxide. Implications for the role of cytochrome P450. Biochem Pharmacol (1993) 0.83
S-methyl-N,N-diethylthiolcarbamate: a disulfiram metabolite and potent rat liver mitochondrial low Km aldehyde dehydrogenase inhibitor. Alcohol (1990) 0.83
Dimethylethanolamine: acute, 2-week, and 13-week inhalation toxicity studies in rats. Fundam Appl Toxicol (1987) 0.83
Characterization of diethyldithiocarbamate methyl ester sulfine as an intermediate in the bioactivation of disulfiram. J Pharmacol Exp Ther (1995) 0.81
Protein phosphorylation and taurine biosynthesis in vivo and in vitro. J Neurosci (1997) 0.81
Acute, pharmacokinetic, and subchronic toxicological studies of 2,4-dichlorophenoxyacetic acid. Fundam Appl Toxicol (1987) 0.81
S-methyl N,N-diethylthiolcarbamate sulfone, an in vitro and in vivo inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol (1994) 0.81
Evaluation of exposure to water aerosol or air by nose-only or whole-body inhalation procedures for CD-1 mice in developmental toxicity studies. Fundam Appl Toxicol (1994) 0.81
Diethyldithiocarbamic acid-methyl ester: a metabolite of disulfiram and its alcohol sensitizing properties in the disulfiram-ethanol reaction. Alcohol (1988) 0.81
Radioactive and nonradioactive methods for the in vivo determination of disulfiram, diethyldithiocarbamate, and diethyldithiocarbamate-methyl ester. Alcohol Clin Exp Res (1978) 0.81
Pulmonary fibrosis produced in F-344 rats by subchronic inhalation of aerosols of a 4000 molecular weight ethylene oxide/propylene oxide polymer. Fundam Appl Toxicol (1988) 0.81
Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation. Alcohol Clin Exp Res (1998) 0.80
Acute and 2-week inhalation toxicity studies on aerosols of selected ethylene oxide/propylene oxide polymers in rats. Fundam Appl Toxicol (1987) 0.80
Subchronic toxicity study of dicyclopentadiene vapor in rats. Toxicol Ind Health (1995) 0.80
Protection with disulfiram from central and pulmonary oxygen toxicity. Biochem Pharmacol (1971) 0.80
S-methyl-N,N-diethylthiocarbamate sulfoxide elicits neuroprotective effect against N-methyl-D-aspartate receptor-mediated neurotoxicity. J Biomed Sci (2001) 0.80
Physiologically based pharmacokinetic modeling with methylchloroform: implications for interspecies, high dose/low dose, and dose route extrapolations. Toxicol Appl Pharmacol (1988) 0.80
Inhibition of rat liver low Km aldehyde dehydrogenase by thiocarbamate herbicides. Occupational implications. Biochem Pharmacol (1995) 0.80
Evaluation of 13-week inhalation toxicity study on methyl t-butyl ether (MTBE) in Fischer 344 rats. J Appl Toxicol (1997) 0.80
A physiologic pharmacokinetic model for styrene and styrene-7,8-oxide in mouse, rat and man. Arch Toxicol (1994) 0.80
Determination of disulfiram and metabolites from biological fluids by high-performance liquid chromatography. J Chromatogr (1980) 0.79
Isolated perfused lung histamine release, lipid peroxidation, and tissue superoxide dismutase from rats exposed to normobaric hyperoxia. Toxicology (1986) 0.79
Regulation of taurine biosynthesis and its physiological significance in the brain. Adv Exp Med Biol (1998) 0.79
Free radical formation and lipid peroxidation in rat and mouse cerebral cortex slices exposed to high oxygen pressure. Brain Res (1982) 0.79
Effect of disulfiram on oxygen toxicity in beagle dogs. Aerosp Med (1974) 0.79
Subchronic oral toxicity, tissue distribution and clearance of hexachloroethane in the rat. Drug Chem Toxicol (1985) 0.78
A 14-week vapor inhalation toxicity study of methyl isobutyl ketone. Fundam Appl Toxicol (1987) 0.78
Mode of action of taurine and regulation dynamics of its synthesis in the CNS. Adv Exp Med Biol (2000) 0.78
Kinetics and metabolism of inhaled methyl chloroform (1,1,1-trichloroethane) in male volunteers. Fundam Appl Toxicol (1984) 0.78
Diethyldithiocarbamate methyl ester sulfoxide, an inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase and putative metabolite of disulfiram. Alcohol Clin Exp Res (1994) 0.77
Diethyldithiocarbamic acid-methyl ester distribution, elimination, and LD50 in the rat after intraperitoneal administration. Alcohol Clin Exp Res (1983) 0.77
Two-generation reproductive toxicity study of inhaled toluene diisocyanate vapor in CD rats. Toxicol Sci (1999) 0.77
Ammonia production in inhalation chambers and its relevance to chlorine inhalation studies. Toxicol Appl Pharmacol (1979) 0.77
Pharmacokinetics of picloram in male volunteers. Toxicol Appl Pharmacol (1984) 0.77
Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. Drug Chem Toxicol (1989) 0.77
Brain energetics in oxygen-induced convulsions. J Neurochem (1974) 0.77
Determination of chlorpyrifos, chlorpyrifos oxon, and 3,5,6-trichloro-2-pyridinol in rat and human blood. J Anal Toxicol (1998) 0.77
Glutathione- and glutathione-S-transferase-dependent oxidative desulfuration of the thione xenobiotic diethyldithiocarbamate methyl ester. Mol Pharmacol (1994) 0.76
Brain gamma-aminobutyric acid, glutamic acid decarboxylase, glutamate, and ammonia in mice during hyperbaric oxygenation. J Neurochem (1977) 0.76
Cerebral oxidized and reduced nicotinamide-adenine dinucleotide phosphate and glucose 6-phosphate dehydrogenase in mice during exposure to high oxygen pressure. Biochem J (1978) 0.76
Developmental toxicity evaluation of inhaled toluene diisocyanate vapor in CD rats. Toxicol Sci (1999) 0.76
NADPH-dependent, regioselective S-oxidation of a thionosulfur- and thioether-containing xenobiotic, diethyldithiocarbamate methyl ester by rat liver microsomes. Drug Metab Dispos (1994) 0.76
Oral and dermal pharmacokinetics of triclopyr in human volunteers. Hum Toxicol (1989) 0.75
Comments on an article by Roy et al. (Teratology 58:62-68, 1998) Teratology (1999) 0.75
Neurotoxic effect of acamprosate, n-acetyl-homotaurine, in cultured neurons. J Biomed Sci (2001) 0.75
Teratologic evaluation of ethylene glycol monobutyl ether in Fischer 344 rats and New Zealand white rabbits following inhalation exposure. Environ Health Perspect (1984) 0.75
Effect of high oxygen pressure on brain norepinephrine and serotonin turnover. Eur J Pharmacol (1973) 0.75
Segregation kinetics of particulate solids systems. IV. Effect of particle shape on energy requirements. J Pharm Sci (1967) 0.75
Hyperbaric oxygenation and brain norepinephrine and 5-hydroxytryptamine: oxygen-pressure interactions. Life Sci (1969) 0.75
Disulfiram and CS2 toxicity. Am J Psychiatry (1978) 0.75
The role of lipid, free radical initiator, and oxygen on the kinetics of lipid peroxidation. Toxicol Appl Pharmacol (1982) 0.75
Dominant lethal assay of 2,4-pentanedione vapor in Fischer 344 rats. Toxicol Ind Health (1989) 0.75
Glutathione and non-protein sulfhydryl in cerebral cortex and lung in mice exposed to high oxygen pressure. Toxicology (1982) 0.75
Brain norepinephrine and serotonin in central oxygen toxicity. Life Sci I (1971) 0.75
Cerebral and blood glucose in central oxygen poisoning. Undersea Biomed Res (1978) 0.75
Post-mortem degradation kinetics of brain norepinephrine. Biochem Pharmacol (1973) 0.75