Published in Biochim Biophys Acta on September 29, 2009
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition. PLoS Biol (2010) 2.21
Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender. FASEB J (2010) 1.16
The endoplasmic reticulum stress response and diabetic kidney disease. Am J Physiol Renal Physiol (2011) 1.16
Liver and diabetes. A vicious circle. Hepatol Res (2013) 1.10
Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance. Cell Rep (2014) 1.06
Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice. Sleep (2015) 0.91
Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. Psychopharmacology (Berl) (2011) 0.89
Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin. Diabetes (2013) 0.85
Brain signaling systems in the Type 2 diabetes and metabolic syndrome: promising target to treat and prevent these diseases. Future Sci OA (2015) 0.81
Obesity and the ageing brain: could leptin play a role in neurodegeneration? Curr Gerontol Geriatr Res (2011) 0.80
A potential role for adjunctive vitamin D therapy in the management of weight gain and metabolic side effects of second-generation antipsychotics. J Pediatr Endocrinol Metab (2011) 0.80
Obesity and insulin resistance: an abridged molecular correlation. Lipid Insights (2013) 0.78
"Mens sana in corpore sano": exercise and hypothalamic ER stress. PLoS Biol (2010) 0.78
Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways. J Lipid Res (2016) 0.76
Circadian Dysfunction and Obesity: Is Leptin the Missing Link? Cell Metab (2015) 0.75
Beneficial Effects of Metformin and/or Salicylate on Palmitate- or TNFα-Induced Neuroinflammatory Marker and Neuropeptide Gene Regulation in Immortalized NPY/AgRP Neurons. PLoS One (2016) 0.75
Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. Cell Metab (2008) 2.89
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat Med (2010) 2.76
BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell (2012) 2.20
AMPK: a metabolic gauge regulating whole-body energy homeostasis. Trends Mol Med (2008) 2.16
Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis. J Clin Invest (2007) 2.03
Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes. Cardiovasc Res (2004) 1.60
Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways. Gastroenterology (2012) 1.58
Adiponectin is synthesized and secreted by human and murine cardiomyocytes. FEBS Lett (2005) 1.58
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity. J Neurosci (2009) 1.54
Using brown adipose tissue to treat obesity - the central issue. Trends Mol Med (2011) 1.51
Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. Diabetes (2006) 1.46
Antibodies to cannabinoid type 1 receptor co-react with stomatin-like protein 2 in mouse brain mitochondria. Eur J Neurosci (2013) 1.45
Nesfatin-1 in human and murine cardiomyocytes: synthesis, secretion, and mobilization of GLUT-4. Endocrinology (2013) 1.41
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes (2012) 1.28
Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus. Endocrinology (2003) 1.24
Effects of obestatin on energy balance and growth hormone secretion in rodents. Endocrinology (2006) 1.21
Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender. FASEB J (2010) 1.16
The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin. Diabetes (2011) 1.16
Glial-derived neurotropic factor and RET gene expression in normal human anterior pituitary cell types and in pituitary tumors. J Clin Endocrinol Metab (2002) 1.16
Influence of chronic undernutrition and leptin on GOAT mRNA levels in rat stomach mucosa. J Mol Endocrinol (2008) 1.12
Energy balance regulation by thyroid hormones at central level. Trends Mol Med (2013) 1.11
Dual action of adiponectin on insulin secretion in insulin-resistant mice. Biochem Biophys Res Commun (2004) 1.10
Expression and regulation of adiponectin and receptor in human and rat placenta. J Clin Endocrinol Metab (2005) 1.09
Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability. Endocrinology (2008) 1.08
Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids. Diabetes (2005) 1.08
Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system. Endocrinology (2011) 1.08
Exendin-4 potently decreases ghrelin levels in fasting rats. Diabetes (2007) 1.07
Ghrelin, obesity and diabetes. Nat Clin Pract Endocrinol Metab (2007) 1.06
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. FASEB J (2005) 1.06
Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neurosci Lett (2005) 1.05
Effect of food restriction on ghrelin in normal-cycling female rats and in pregnancy. Obes Res (2002) 1.04
Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion. Endocrinology (2009) 1.04
Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance. Diabetes (2010) 1.02
The brain and brown fat. Ann Med (2014) 1.02
Resistin is expressed in different rat tissues and is regulated in a tissue- and gender-specific manner. FEBS Lett (2003) 1.02
Analysis of EEG background activity in Alzheimer's disease patients with Lempel-Ziv complexity and central tendency measure. Med Eng Phys (2005) 1.01
Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism. J Pathol (2012) 1.01
A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. J Endocrinol (2011) 1.00
SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: relevance for metabolic side-effects? Mol Cell Biochem (2006) 0.99
Hypothalamic control of lipid metabolism: focus on leptin, ghrelin and melanocortins. Neuroendocrinology (2011) 0.98
Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion. Endocrinology (2008) 0.98
Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. Int J Neuropsychopharmacol (2008) 0.98
The endocannabinoid system: role in glucose and energy metabolism. Pharmacol Res (2009) 0.97
Irisin, two years later. Int J Endocrinol (2013) 0.97
Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin. PLoS One (2012) 0.97
Novel expression of resistin in rat testis: functional role and regulation by nutritional status and hormonal factors. J Cell Sci (2004) 0.97
Regulation of resistin by gonadal, thyroid hormone, and nutritional status. Obes Res (2003) 0.97
Hypothalamic AMP-activated protein kinase as a mediator of whole body energy balance. Rev Endocr Metab Disord (2011) 0.95
Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells. J Psychopharmacol (2010) 0.94
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. BMC Pharmacol (2009) 0.93
Ghrelin and lipid metabolism: key partners in energy balance. J Mol Endocrinol (2011) 0.92
The opioid system and food intake: homeostatic and hedonic mechanisms. Obes Facts (2012) 0.92
Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice. Am J Physiol Endocrinol Metab (2008) 0.91
Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats. Endocrinology (2014) 0.90
Oleoylethanolamide: effects on hypothalamic transmitters and gut peptides regulating food intake. Neuropharmacology (2010) 0.90
Peripheral tissue-brain interactions in the regulation of food intake. Proc Nutr Soc (2007) 0.89
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes (2013) 0.89
The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat. J Neurosci (2010) 0.89