Published in Proc Natl Acad Sci U S A on October 12, 2009
Clonal evolution in cancer. Nature (2012) 11.07
Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates. Nat Rev Immunol (2013) 1.39
Evolutionary determinants of cancer. Cancer Discov (2015) 1.19
The role of the Major Histocompatibility Complex in the spread of contagious cancers. Mamm Genome (2010) 1.03
Cancer stem cells as 'units of selection'. Evol Appl (2012) 0.94
Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence". Cancer Metastasis Rev (2013) 0.86
Cancer in the parasitic protozoans Trypanosoma brucei and Toxoplasma gondii. Proc Natl Acad Sci U S A (2015) 0.84
Immunology of naturally transmissible tumours. Immunology (2015) 0.82
How the devil facial tumor disease escapes host immune responses. Oncoimmunology (2013) 0.81
The role of MHC genes in contagious cancer: the story of Tasmanian devils. Immunogenetics (2017) 0.81
Testing the theory of immune selection in cancers that break the rules of transplantation. Cancer Immunol Immunother (2009) 0.78
A Sixth Modality of Infectious Disease: Contagious Cancer from Devils to Clams and Beyond. PLoS Pathog (2016) 0.75
Epstein-Barr-Virus-Positive B-Cell Lymphoma of Recipient Origin Despite of the Elimination of Clonally EBV-Infected T Cells by Allogeneic Stem Cell Transplantation in a Patient with Chronic Active EBV Infection. Case Rep Transplant (2012) 0.75
Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'. Chimerism (2015) 0.75
Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature (2007) 17.68
A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays. Cancer Res (2005) 11.02
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature (2008) 10.12
Microdroplet testing for HLA-A, -B, -C, and -D antigens. The Phillip Levine Award Lecture. Am J Clin Pathol (1978) 6.88
Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer (2003) 4.58
Clonal origin and evolution of a transmissible cancer. Cell (2006) 3.60
Loss of mismatched HLA in leukemia after stem-cell transplantation. N Engl J Med (2009) 3.38
Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc Natl Acad Sci U S A (1997) 2.45
Leukemia in twins: lessons in natural history. Blood (2003) 2.37
Transplacental transmission of natural-killer-cell lymphoma. N Engl J Med (1999) 2.23
Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial. Proc Natl Acad Sci U S A (2007) 2.03
Strategies of tumor immune evasion. BioDrugs (2005) 1.26
Metastatic melanoma in pregnancy: risk of transplacental metastases in the infant. J Clin Oncol (2003) 1.20
Loss of the Y chromosome from normal and neoplastic bone marrows. United Kingdom Cancer Cytogenetics Group (UKCCG) Genes Chromosomes Cancer (1992) 0.97
Acquired X-chromosome aneuploidy in children with acute lymphoblastic leukemia. Med Pediatr Oncol (1999) 0.88
Donor transmitted disease: cancer. Transplant Proc (1991) 0.87
Transplacental transmission of maternal B-cell lymphoma. Am J Obstet Gynecol (2004) 0.80
Signatures of mutational processes in human cancer. Nature (2013) 21.63
Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature (2010) 8.48
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet (2010) 7.96
A more efficient method to generate integration-free human iPS cells. Nat Methods (2011) 7.39
Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood (2005) 6.05
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity (2006) 4.75
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet (2009) 4.47
LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res (2002) 3.73
Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms. Blood (2009) 3.69
Acute lymphoblastic leukaemia. Lancet (2013) 3.44
Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. Science (2008) 3.38
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome. Cell Metab (2006) 3.38
Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc Natl Acad Sci U S A (2002) 2.58
Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study. Blood (2009) 2.57
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nat Genet (2010) 2.47
High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism. Blood (2007) 2.46
Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia. Blood (2008) 2.41
Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia. Blood (2010) 2.38
Leukemia in twins: lessons in natural history. Blood (2003) 2.37
Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria. Kidney Int (2008) 2.14
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell (2008) 2.13
Single-cell mutational profiling and clonal phylogeny in cancer. Genome Res (2013) 2.10
Clinical course of patients with WASP gene mutations. Blood (2003) 2.06
In search of the original leukemic clone in chronic myeloid leukemia patients in complete molecular remission after stem cell transplantation or imatinib. Blood (2010) 1.98
IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors. Nature (2010) 1.76
Phosphorylation of histone H2AX at M phase in human cells without DNA damage response. Biochem Biophys Res Commun (2005) 1.73
In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia. Blood (2002) 1.71
Identification of a gene expression signature associated with pediatric AML prognosis. Blood (2003) 1.71
TEL deletion analysis supports a novel view of relapse in childhood acute lymphoblastic leukemia. Clin Cancer Res (2004) 1.70
Related transplantation with HLA-1 Ag mismatch in the GVH direction and HLA-8/8 allele-matched unrelated transplantation: a nationwide retrospective study. Blood (2011) 1.65
Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection. Am J Hematol (2005) 1.65
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood. Blood (2009) 1.64
Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21. Proc Natl Acad Sci U S A (2006) 1.63
MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia. Blood (2010) 1.62
An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell (2012) 1.61
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity. Curr Biol (2009) 1.61
Features and outcome of neonatal leukemia in Japan: experience of the Japan infant leukemia study group. Pediatr Blood Cancer (2006) 1.56
Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity. J Cell Biol (2002) 1.54
RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes. J Biol Chem (2006) 1.52
Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation. Blood (2010) 1.52
X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options. Blood (2010) 1.51
Clinical application of array-based comparative genomic hybridization by two-stage screening for 536 patients with mental retardation and multiple congenital anomalies. J Hum Genet (2010) 1.49
EZH2 mutational status predicts poor survival in myelofibrosis. Blood (2011) 1.45
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. Blood (2013) 1.45
HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism. Blood (2008) 1.44
Comparison of intravenous with oral busulfan in allogeneic hematopoietic stem cell transplantation with myeloablative conditioning regimens for pediatric acute leukemia. Biol Blood Marrow Transplant (2013) 1.42
Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. Blood (2003) 1.40
Prognostic factors for chronic active Epstein-Barr virus infection. J Infect Dis (2003) 1.36
Autoimmune lymphoproliferative syndrome-like disease with somatic KRAS mutation. Blood (2010) 1.32
The histone deacetylase 9 gene encodes multiple protein isoforms. J Biol Chem (2003) 1.32
Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia. Blood (2011) 1.31
Epitopes of human leukocyte antigen class I antibodies found in sera of normal healthy males and cord blood. Hum Immunol (2009) 1.29
Identification of preleukemic precursors of hyperdiploid acute lymphoblastic leukemia in cord blood. Genes Chromosomes Cancer (2004) 1.27
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood (2003) 1.26
Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis. J Clin Invest (2005) 1.26
Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell-replete marrow from an unrelated donor. Biol Blood Marrow Transplant (2007) 1.26
Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study. Blood (2011) 1.25
Use of a comprehensive polymerase chain reaction system for diagnosis of ocular infectious diseases. Ophthalmology (2013) 1.25
Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase. J Med Dent Sci (2003) 1.25
The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils. Nat Immunol (2012) 1.25
Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice. Proc Natl Acad Sci U S A (2004) 1.23
Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia. Oncogene (2004) 1.23
Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients. J Immunol (2009) 1.23
Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2. Clin Immunol (2005) 1.21
Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition. J Biol Chem (2008) 1.20
Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis. Arthritis Res Ther (2009) 1.19
Infant acute lymphoblastic leukemia with MLL gene rearrangements: outcome following intensive chemotherapy and hematopoietic stem cell transplantation. Blood (2004) 1.18
Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. Genes Chromosomes Cancer (2006) 1.17
Oxidative stress induces nuclear loss of DNA repair proteins Ku70 and Ku80 and apoptosis in pancreatic acinar AR42J cells. J Biol Chem (2003) 1.17
Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice. Blood (2011) 1.16
Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements. Cancer Res (2003) 1.16
The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells. J Clin Invest (2009) 1.15
Identification of severe combined immunodeficiency by T-cell receptor excision circles quantification using neonatal guthrie cards. J Pediatr (2009) 1.15
NOTCH1 mutation can be an early, prenatal genetic event in T-ALL. Blood (2007) 1.15
Genetic lesions in a preleukemic aplasia phase in a child with acute lymphoblastic leukemia. Genes Chromosomes Cancer (2008) 1.14
Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction. Proc Natl Acad Sci U S A (2002) 1.14
FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma. Br J Haematol (2009) 1.12
Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia. Blood (2012) 1.11
Galectin-3 (Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia. Proc Natl Acad Sci U S A (2011) 1.10