Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms.

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Published in Clin Microbiol Rev on October 01, 2009

Authors

Philip D Lister1, Daniel J Wolter, Nancy D Hanson

Author Affiliations

1: Department of Medical Microbiology and Immunology, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA. pdlister@creighton.edu

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First occurrence of a Pseudomonas aeruginosa isolate in the United States producing an IMP metallo-beta-lactamase, IMP-18. Antimicrob Agents Chemother (2006) 1.30

Insertional inactivation of oprD in clinical isolates of Pseudomonas aeruginosa leading to carbapenem resistance. FEMS Microbiol Lett (2004) 1.21

The ACT-1 plasmid-encoded AmpC beta-lactamase is inducible: detection in a complex beta-lactamase background. J Antimicrob Chemother (2002) 1.21

Association between handling of pet treats and infection with Salmonella enterica serotype newport expressing the AmpC beta-lactamase, CMY-2. J Clin Microbiol (2003) 1.20

Model system to evaluate the effect of ampD mutations on AmpC-mediated beta-lactam resistance. Antimicrob Agents Chemother (2006) 1.12

Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital. Diagn Microbiol Infect Dis (2004) 1.11

AmpC and OprD are not involved in the mechanism of imipenem hypersusceptibility among Pseudomonas aeruginosa isolates overexpressing the mexCD-oprJ efflux pump. Antimicrob Agents Chemother (2005) 1.10

Role of ampD homologs in overproduction of AmpC in clinical isolates of Pseudomonas aeruginosa. Antimicrob Agents Chemother (2008) 1.06

Analyses of ampC gene expression in Serratia marcescens reveal new regulatory properties. J Antimicrob Chemother (2003) 1.03

Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. Antimicrob Agents Chemother (2010) 1.02

Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense. PLoS Pathog (2013) 1.01

Rapid multiplex PCR assay for identification of USA300 community-associated methicillin-resistant Staphylococcus aureus isolates. J Clin Microbiol (2006) 1.00

Community-onset disease caused by Citrobacter freundii producing a novel CTX-M beta-lactamase, CTX-M-30, in Canada. Antimicrob Agents Chemother (2004) 0.99

Plasmid-encoded functions compensate for the biological cost of AmpC overexpression in a clinical isolate of Salmonella typhimurium. J Antimicrob Chemother (2004) 0.99

bla(KPC) RNA expression correlates with two transcriptional start sites but not always with gene copy number in four genera of Gram-negative pathogens. Antimicrob Agents Chemother (2011) 0.98

Factors influencing gene expression and resistance for Gram-negative organisms expressing plasmid-encoded ampC genes of Enterobacter origin. J Antimicrob Chemother (2003) 0.95

Emergence of carbapenem resistance in Pseudomonas aeruginosa isolates from a patient with cystic fibrosis in the absence of carbapenem therapy. Clin Infect Dis (2008) 0.94

Pediatric infection due to multiresistant Salmonella enterica serotype Infantis in Honduras. J Clin Microbiol (2004) 0.94

Identification of bla(CMY-7) and associated plasmid-mediated resistance genes in multidrug-resistant Escherichia coli isolated from dogs at a veterinary teaching hospital in Australia. J Antimicrob Chemother (2006) 0.92

Characterization of CTX-M ESBLs in Enterobacter cloacae, Escherichia coli and Klebsiella pneumoniae clinical isolates from Cairo, Egypt. BMC Infect Dis (2009) 0.91

Levofloxacin/imipenem prevents the emergence of high-level resistance among Pseudomonas aeruginosa strains already lacking susceptibility to one or both drugs. J Antimicrob Chemother (2006) 0.88

Isolation and characterization of an epidemic methicillin-resistant Staphylococcus aureus 15 variant in the central United States. J Clin Microbiol (2008) 0.87

Point mutations in the inc antisense RNA gene are associated with increased plasmid copy number, expression of blaCMY-2 and resistance to piperacillin/tazobactam in Escherichia coli. J Antimicrob Chemother (2011) 0.87

Identification of plasmid-mediated extended-spectrum and AmpC beta-lactamases in Enterobacter spp. isolated from dogs. J Med Microbiol (2007) 0.87

Levofloxacin-imipenem combination prevents the emergence of resistance among clinical isolates of Pseudomonas aeruginosa. Clin Infect Dis (2005) 0.86

Promoter sequences necessary for high-level expression of the plasmid-associated ampC beta-lactamase gene blaMIR-1. Antimicrob Agents Chemother (2004) 0.86

Rapid detection and statistical differentiation of KPC gene variants in Gram-negative pathogens by use of high-resolution melting and ScreenClust analyses. J Clin Microbiol (2012) 0.86

Multiple genotypic changes in hypersusceptible strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients do not always correlate with the phenotype. J Antimicrob Chemother (2009) 0.84

Increased expression of ampC in Pseudomonas aeruginosa mutants selected with ciprofloxacin. Antimicrob Agents Chemother (2007) 0.84

Development of a TaqMan multiplex PCR assay for detection of plasmid-mediated ampC β-lactamase genes. J Clin Microbiol (2012) 0.83

Emergence and spread of two distinct clonal groups of multidrug-resistant Escherichia coli in a veterinary teaching hospital in Australia. J Med Microbiol (2006) 0.81

Production of KPC-2 alone does not always result in β-lactam MICs representing resistance in gram-negative pathogens. J Clin Microbiol (2012) 0.80

First report of CTX-M-14 producing clinical isolates of Salmonella serovar Typhimurium from Egypt. J Infect Dev Ctries (2009) 0.80

Purification, crystallization and preliminary X-ray analysis of IMP-18, a class B carbapenemase from Pseudomonas aeruginosa. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.79

Rapid PCR amplification protocols decrease the turn-around time for detection of antibiotic resistance genes in Gram-negative pathogens. Diagn Microbiol Infect Dis (2013) 0.78

In vitro development of resistance to DX-619 and other quinolones in enterococci. J Antimicrob Chemother (2006) 0.77

Multiplex high-resolution melting analysis as a diagnostic tool for detection of plasmid-mediated AmpC β-lactamase genes. J Clin Microbiol (2014) 0.76

New quality control strain for use in routine testing for production of extended-spectrum Beta-lactamases by enterobacteriaceae. J Clin Microbiol (2005) 0.75

In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci. Antimicrob Agents Chemother (2007) 0.75

Association of IS5 with divergent tandem blaCMY-2 genes in clinical isolates of Escherichia coli. J Antimicrob Chemother (2011) 0.75

Effect of drug treatment options on the mobility and expression of blaKPC. J Antimicrob Chemother (2013) 0.75

Editorial: Resistance in gram-negative pathogens: a threat to global health. Curr Pharm Des (2013) 0.75