Published in Am J Clin Nutr on October 14, 2009
Eating Behavior in Children | NCT00320177
Metabolic Differences of Overweight Children and Children of Overweight Parents | NCT00001522
Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet (2010) 4.37
Methodological challenges of genome-wide association analysis in Africa. Nat Rev Genet (2010) 2.27
A link between FTO, ghrelin, and impaired brain food-cue responsivity. J Clin Invest (2013) 2.23
The genetics of obesity: FTO leads the way. Trends Genet (2010) 1.90
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. PLoS One (2010) 1.89
The bigger picture of FTO: the first GWAS-identified obesity gene. Nat Rev Endocrinol (2013) 1.73
From monogenic to polygenic obesity: recent advances. Eur Child Adolesc Psychiatry (2010) 1.49
Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice. Cell Metab (2014) 1.42
Rationale and design of the Feeding Dynamic Intervention (FDI) study for self-regulation of energy intake in preschoolers. Contemp Clin Trials (2015) 1.41
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse. PLoS Genet (2013) 1.31
The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China. BMC Med Genet (2010) 1.31
Ghrelin. Mol Metab (2015) 1.29
Nutrigenetics and metabolic disease: current status and implications for personalised nutrition. Nutrients (2013) 1.20
Genetics of eating behavior: established and emerging concepts. Nutr Rev (2011) 1.14
FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet (2014) 1.11
The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women. PLoS One (2011) 1.03
Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier. J Obes (2011) 1.02
FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting. PLoS One (2011) 1.02
Are obesity risk genes associated with binge eating in adolescence? Obesity (Silver Spring) (2015) 0.97
Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study. Am J Epidemiol (2013) 0.94
Early determinants of obesity: genetic, epigenetic, and in utero influences. Int J Pediatr (2012) 0.92
Obesity susceptibility loci and uncontrolled eating, emotional eating and cognitive restraint behaviors in men and women. Obesity (Silver Spring) (2013) 0.92
Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly. PLoS One (2011) 0.91
Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children. Int J Obes (Lond) (2012) 0.90
Early intervention of eating- and weight-related problems. J Clin Psychol Med Settings (2010) 0.89
FTO at rs9939609, food responsiveness, emotional control and symptoms of ADHD in preschool children. PLoS One (2012) 0.89
Links between mothers' and children's disinhibited eating and children's adiposity. Appetite (2010) 0.88
The genetics of childhood obesity and interaction with dietary macronutrients. Genes Nutr (2013) 0.87
A twin study of self-regulatory eating in early childhood: estimates of genetic and environmental influence, and measurement considerations. Int J Obes (Lond) (2012) 0.86
Gene-diet interactions in childhood obesity. Curr Genomics (2011) 0.86
Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents. Diabetes (2015) 0.85
Counseling and behavior change in pediatric obesity. Pediatr Clin North Am (2011) 0.85
FTO gene variant and risk of overweight and obesity among children and adolescents: a systematic review and meta-analysis. PLoS One (2013) 0.84
Genetic variation in the fat mass and obesity-associated gene (FTO) in association with food preferences in healthy adults. Food Nutr Res (2013) 0.84
Shared genetic contributions of fruit and vegetable consumption with BMI in families 20 y after sharing a household. Am J Clin Nutr (2011) 0.82
Hedonic hunger prospectively predicts onset and maintenance of loss of control eating among college women. Health Psychol (2015) 0.81
The biology of FTO: from nucleic acid demethylase to amino acid sensor. Diabetologia (2013) 0.81
Pediatric obesity. An introduction. Appetite (2015) 0.81
Binge eating disorder: the next generation of research. Int J Eat Disord (2013) 0.80
Association of gene polymorphism of the fat mass and obesity associated gene with metabolic syndrome: a retrospective cohort study in Japanese workers. Yonago Acta Med (2012) 0.80
Is there a genetic cause of appetite loss?-an explorative study in 1,853 cancer patients. J Cachexia Sarcopenia Muscle (2012) 0.79
Effect of FTO Gene and Physical Activity Interaction on Trunk Fat Percentage Among the Newfoundland Population. Genet Epigenet (2014) 0.79
The effects of genetic variation in FTO rs9939609 on obesity and dietary preferences in Chinese Han children and adolescents. PLoS One (2014) 0.78
FTO knockdown in rat ventromedial hypothalamus does not affect energy balance. Physiol Rep (2014) 0.78
Association between rs9930506 polymorphism of the fat mass & obesity-associated (FTO) gene & onset of obesity in Polish adults. Indian J Med Res (2016) 0.78
Polymorphisms FTO rs9939609, PPARG rs1801282 and ADIPOQ rs4632532 and rs182052 but not lifestyle are associated with obesity related-traits in Mexican children. Genet Mol Biol (2016) 0.78
Resting-State Brain and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes. Front Hum Neurosci (2016) 0.77
The effects of fat mass and obesity-associated gene variants on the body mass index among ethnic groups and in children and adults. Indian J Endocrinol Metab (2012) 0.77
FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More? Front Endocrinol (Lausanne) (2011) 0.77
Appetitive traits as behavioural pathways in genetic susceptibility to obesity: a population-based cross-sectional study. Sci Rep (2015) 0.77
Uncovering the biology of FTO. Mol Metab (2012) 0.76
Puberty and the manifestations of loss of control eating in children and adolescents. Int J Eat Disord (2014) 0.76
Fat mass and obesity-associated gene (FTO) is associated to eating disorders susceptibility and moderates the expression of psychopathological traits. PLoS One (2017) 0.75
A patient with a novel homozygous missense mutation in FTO and concomitant nonsense mutation in CETP. J Hum Genet (2016) 0.75
Correlates of the FTO gene variant (rs9939609) and growth of American Indian infants. Genet Test Mol Biomarkers (2011) 0.75
Fat mass and obesity associated (FTO) gene influences skeletal muscle phenotypes in non-resistance trained males and elite rugby playing position. BMC Genet (2017) 0.75
Television food advertisement exposure and FTO rs9939609 genotype in relation to excess consumption in children. Int J Obes (Lond) (2016) 0.75
Genetic variants in AKR1B10 associate with human eating behavior. BMC Genet (2015) 0.75
Does FTO have a paradoxical effect in fetal life? BMC Genet (2014) 0.75
FTO association and interaction with time spent sitting. Int J Obes (Lond) (2015) 0.75
Emotion dysregulation and loss-of-control eating in children and adolescents. Health Psychol (2016) 0.75
Gender-Dependent Association of FTO Polymorphisms with Body Mass Index in Mexicans. PLoS One (2016) 0.75
Assessing gene-environment interaction effects of FTO, MC4R and lifestyle factors on obesity using an extreme phenotype sampling design: Results from the HUNT study. PLoS One (2017) 0.75
The Interplay of Genetics and Environmental Factors in the Development of Obesity. Cureus (2017) 0.75
Genetic association of FTO/IRX region with obesity and overweight in the Polish population. PLoS One (2017) 0.75
Tailoring pharmacotherapy to specific eating behaviours in obesity: Can recommendations for personalised therapy be made from the current data? Acta Diabetol (2017) 0.75
CDC growth charts: United States. Adv Data (2000) 38.32
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA (2002) 23.79
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet (2007) 13.62
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science (2007) 9.86
An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med (2008) 5.88
Inactivation of the Fto gene protects from obesity. Nature (2009) 5.61
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One (2007) 4.92
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes (2007) 4.19
Regulation of Fto/Ftm gene expression in mice and humans. Am J Physiol Regul Integr Comp Physiol (2008) 3.49
Relation between dieting and weight change among preadolescents and adolescents. Pediatrics (2003) 3.36
The fat mass- and obesity-associated locus and dietary intake in children. Am J Clin Nutr (2008) 3.18
Physical activity and the association of common FTO gene variants with body mass index and obesity. Arch Intern Med (2008) 3.15
Naturalistic weight-reduction efforts prospectively predict growth in relative weight and onset of obesity among female adolescents. J Consult Clin Psychol (1999) 3.01
A new air displacement method for the determination of human body composition. Med Sci Sports Exerc (1995) 2.87
Test-retest reliability of the eating disorder examination. Int J Eat Disord (2000) 2.83
Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity (Silver Spring) (2008) 2.68
The use of the eating disorder examination with children: a pilot study. Int J Eat Disord (1996) 2.56
The FTO gene and measured food intake in children. Int J Obes (Lond) (2008) 2.42
Eating-disordered behaviors, body fat, and psychopathology in overweight and normal-weight children. J Consult Clin Psychol (2004) 2.37
A prospective study of psychological predictors of body fat gain among children at high risk for adult obesity. Pediatrics (2006) 2.28
Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene. Am J Clin Nutr (2009) 2.14
Variation in the FTO gene influences food intake but not energy expenditure. Exp Clin Endocrinol Diabetes (2008) 1.96
A prospective study of loss of control eating for body weight gain in children at high risk for adult obesity. Int J Eat Disord (2009) 1.93
Randomized, controlled trial of an internet-facilitated intervention for reducing binge eating and overweight in adolescents. Pediatrics (2008) 1.90
FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity. J Clin Endocrinol Metab (2009) 1.87
Association of the FTO gene with BMI. Obesity (Silver Spring) (2008) 1.79
A multisite investigation of binge eating behaviors in children and adolescents. J Consult Clin Psychol (2007) 1.72
Laboratory assessment of the food intake of children and adolescents with loss of control eating. Am J Clin Nutr (2009) 1.64
Situational effects on meal intake: A comparison of eating alone and eating with others. Physiol Behav (2006) 1.61
Sources of energy and six nutrients in diets of low-income Hispanic-American women and their children: quantitative data from HHANES, 1982-1984. J Am Diet Assoc (1995) 1.40
Effects of binge eating on satiation, satiety, and energy intake of overweight children. Am J Clin Nutr (2006) 1.30
Laboratory studies of binge eating disorder. Int J Eat Disord (2003) 1.22
The relation between skeletal maturation and adiposity in African American and Caucasian children. J Pediatr (2001) 1.09
Dietary energy density affects fat mass in early adolescence and is not modified by FTO variants. PLoS One (2009) 1.07
Effects of acute food deprivation on eating behavior in eating disorders. Int J Eat Disord (2000) 0.96
Obesity, FTO gene variant, and energy intake in children. N Engl J Med (2009) 0.95
A naturalistic evaluation of the relation between dietary restraint, the urge to binge, and actual binge eating: a clarification. Int J Eat Disord (2005) 0.84
Caloric intake patterns of nonpurge binge-eating women. West J Nurs Res (1998) 0.81
Compulsive eating and dietary restraint. Br J Clin Psychol (1987) 0.79
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care (2007) 14.35
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
The epidemiology of obesity. Gastroenterology (2007) 8.35
Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med (2009) 8.06
Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med (2008) 5.34
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol (2013) 5.24
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation (2013) 5.02
Obesity. N Engl J Med (2002) 4.29
Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery. Surg Obes Relat Dis (2007) 3.67
2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 3.63
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology (2004) 3.61
Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA (2013) 3.57
2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 3.35
High adiposity and high body mass index-for-age in US children and adolescents overall and by race-ethnic group. Am J Clin Nutr (2010) 3.22
The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults. J Clin Endocrinol Metab (2004) 3.13
Brain-derived neurotrophic factor and obesity in the WAGR syndrome. N Engl J Med (2008) 2.91
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene. Diabetes (2006) 2.87
Eating-disordered behaviors, body fat, and psychopathology in overweight and normal-weight children. J Consult Clin Psychol (2004) 2.37
A prospective study of psychological predictors of body fat gain among children at high risk for adult obesity. Pediatrics (2006) 2.28
Orthopedic complications of overweight in children and adolescents. Pediatrics (2006) 2.25
Prevalence of alcohol use disorders before and after bariatric surgery. JAMA (2012) 2.02
A prospective study of loss of control eating for body weight gain in children at high risk for adult obesity. Int J Eat Disord (2009) 1.93
Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab (2004) 1.92
Obesity prevalence in the United States--up, down, or sideways? N Engl J Med (2011) 1.91
A prospective study of pediatric loss of control eating and psychological outcomes. J Abnorm Psychol (2011) 1.89
Assessing weight-related quality of life in adolescents. Obesity (Silver Spring) (2006) 1.85
The perceived onset of dieting and loss of control eating behaviors in overweight children. Int J Eat Disord (2005) 1.78
Suboptimal control of glycemia, blood pressure, and LDL cholesterol in overweight adults with diabetes: the Look AHEAD Study. J Diabetes Complications (2008) 1.77
Obesity-related hypoferremia is not explained by differences in reported intake of heme and nonheme iron or intake of dietary factors that can affect iron absorption. J Am Diet Assoc (2008) 1.77
Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency. J Clin Endocrinol Metab (2004) 1.73
A multisite investigation of binge eating behaviors in children and adolescents. J Consult Clin Psychol (2007) 1.72
Loss of control over eating, adiposity, and psychopathology in overweight children. Int J Eat Disord (2002) 1.71
Baseline characteristics of participants in the Longitudinal Assessment of Bariatric Surgery-2 (LABS-2) study. Surg Obes Relat Dis (2013) 1.70
Indices of insulin action, disposal, and secretion derived from fasting samples and clamps in normal glucose-tolerant black and white children. Diabetes Care (2002) 1.68
Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children: changes during development. Clin Endocrinol (Oxf) (2008) 1.67
Laboratory assessment of the food intake of children and adolescents with loss of control eating. Am J Clin Nutr (2009) 1.64
Binge eating in overweight treatment-seeking adolescents. J Pediatr Psychol (2006) 1.64
Health-related quality of life in overweight and nonoverweight black and white adolescents. J Pediatr (2005) 1.60
Insulin resistance, hyperinsulinemia, and energy intake in overweight children. J Pediatr (2008) 1.59
Psychological status and weight-related distress in overweight or at-risk-for-overweight children. Obesity (Silver Spring) (2006) 1.58
Longitudinal study of the diagnosis of components of the metabolic syndrome in individuals with binge-eating disorder. Am J Clin Nutr (2010) 1.58
Salience of loss of control for pediatric binge episodes: does size really matter? Int J Eat Disord (2010) 1.53
Validity of self-reported weights following bariatric surgery. JAMA (2013) 1.51
The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans. Clin Endocrinol (Oxf) (2006) 1.50
Self-assessment of pubertal stage in overweight children. Pediatrics (2002) 1.48
Disordered-eating attitudes in relation to bone mineral density and markers of bone turnover in overweight adolescents. J Adolesc Health (2009) 1.42
Relationship of body mass index with demographic and clinical characteristics in the Longitudinal Assessment of Bariatric Surgery (LABS). Surg Obes Relat Dis (2008) 1.41
Hormonal responses and test meal intake among obese teenagers before and after laparoscopic adjustable gastric banding. Am J Clin Nutr (2013) 1.41
Which metric of relative weight best captures body fatness in children? Obes Res (2003) 1.39
Sex differences in visceral adipose tissue volume among African Americans. Am J Clin Nutr (2002) 1.35
Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions. Obes Res (2002) 1.34
Preventing excessive weight gain in adolescents: interpersonal psychotherapy for binge eating. Obesity (Silver Spring) (2007) 1.33
Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial. Diabetes (2011) 1.32
Effects of binge eating on satiation, satiety, and energy intake of overweight children. Am J Clin Nutr (2006) 1.30
Influence of excess adiposity on exercise fitness and performance in overweight children and adolescents. Pediatrics (2005) 1.29
Comparison of assessments of children's eating-disordered behaviors by interview and questionnaire. Int J Eat Disord (2003) 1.29
Pediatricians' and family physicians' weight-related care of children in the U.S. Am J Prev Med (2011) 1.29
Loss of control eating disorder in children age 12 years and younger: proposed research criteria. Eat Behav (2008) 1.25
The stability of metabolic syndrome in children and adolescents. J Clin Endocrinol Metab (2009) 1.23
Pediatric obesity: etiology and treatment. Endocrinol Metab Clin North Am (2009) 1.22
Challenges and opportunities of defining clinical leptin resistance. Cell Metab (2012) 1.21
Eating in the absence of hunger in adolescents: intake after a large-array meal compared with that after a standardized meal. Am J Clin Nutr (2010) 1.21