EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication.

PubWeight™: 1.16‹?› | Rank: Top 10%

🔗 View Article (PMC 2757719)

Published in PLoS Pathog on October 16, 2009

Authors

Feroz Sarkari1, Teresa Sanchez-Alcaraz, Shan Wang, Melissa N Holowaty, Yi Sheng, Lori Frappier

Author Affiliations

1: Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

Articles citing this

Regulation of proteolysis by human deubiquitinating enzymes. Biochim Biophys Acta (2013) 1.42

Identification of a novel human papillomavirus by metagenomic analysis of samples from patients with febrile respiratory illness. PLoS One (2013) 1.19

Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection. J Virol (2012) 1.03

Deubiquitinases and the new therapeutic opportunities offered to cancer. Endocr Relat Cancer (2015) 1.02

Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response. J Virol (2011) 1.01

The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies. PLoS One (2011) 1.00

Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate. Genome Res (2014) 0.98

Epstein-Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of survivin. Virology (2010) 0.98

Epstein-Barr virus latent genes. Exp Mol Med (2015) 0.96

Proteomic profiling of EBNA1-host protein interactions in latent and lytic Epstein-Barr virus infections. J Virol (2012) 0.96

The ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA. J Virol (2012) 0.92

Viral takeover of the host ubiquitin system. Front Microbiol (2011) 0.90

Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes. PLoS One (2010) 0.87

USP7/HAUSP promotes the sequence-specific DNA binding activity of p53. PLoS One (2010) 0.87

A role for USP7 in DNA replication. Mol Cell Biol (2013) 0.86

Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis. J Clin Invest (2016) 0.86

Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. J Biol Chem (2013) 0.85

The Epstein-Barr Virus EBNA1 Protein. Scientifica (Cairo) (2012) 0.85

Kaposi's Sarcoma-Associated Herpesvirus Genome Replication, Partitioning, and Maintenance in Latency. Front Microbiol (2012) 0.84

The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins. Nucleic Acids Res (2013) 0.84

Nucleolin is important for Epstein-Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription. Proc Natl Acad Sci U S A (2013) 0.83

USP7 cooperates with SCML2 to regulate the activity of PRC1. Mol Cell Biol (2015) 0.83

A ubiquitin-specific protease possesses a decisive role for adenovirus replication and oncogene-mediated transformation. PLoS Pathog (2013) 0.82

Epstein-Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation. Nucleic Acids Res (2013) 0.81

Inhibition of human papillomavirus DNA replication by an E1-derived p80/UAF1-binding peptide. J Virol (2012) 0.80

Replication of Epstein-Barr viral DNA. Cold Spring Harb Perspect Biol (2013) 0.80

Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7. PLoS Pathog (2015) 0.80

The ubiquitin-conjugating system: multiple roles in viral replication and infection. Cells (2014) 0.79

Usp7 protects genomic stability by regulating Bub3. Oncotarget (2014) 0.77

Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype? Pathogens (2012) 0.77

RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break Repair. Genes (Basel) (2015) 0.77

Epigenetic Impact on EBV Associated B-Cell Lymphomagenesis. Biomolecules (2016) 0.75

HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response. Sci Rep (2015) 0.75

Undercover: gene control by metabolites and metabolic enzymes. Genes Dev (2016) 0.75

Understanding Epstein-Barr Virus Life Cycle with Proteomics: A Temporal Analysis of Ubiquitination During Virus Reactivation. OMICS (2017) 0.75

UbE2E1/UBCH6 is a critical in vivo E2 for the PRC1 catalyzed ubiquitination of H2A at K119. J Biol Chem (2017) 0.75

EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape. Mol Cell (2016) 0.75

Articles cited by this

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature (2002) 7.71

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region. Cell (1985) 7.17

A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components. Mol Cell Biol (1985) 6.44

trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1. Mol Cell Biol (1986) 6.00

Persistence of the Epstein-Barr virus and the origins of associated lymphomas. N Engl J Med (2004) 5.61

Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur J Biochem (1986) 4.80

Histone ubiquitination: triggering gene activity. Mol Cell (2008) 4.42

The Epstein-Barr virus origin of plasmid replication, oriP, contains both the initiation and termination sites of DNA replication. Cell (1989) 4.16

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat Cell Biol (2006) 4.14

A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell (2004) 4.05

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell (2005) 4.04

A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1, a viral protein required for viral DNA replication during latent infection. J Virol (1989) 3.66

A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell (2008) 3.60

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature (2008) 3.53

Acetylation of p53 inhibits its ubiquitination by Mdm2. J Biol Chem (2002) 3.37

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J (1997) 3.34

H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation. Mol Cell (2008) 3.32

Isolation of human sequences that replicate autonomously in human cells. Mol Cell Biol (1989) 3.16

Isolation of three proteins that bind to mammalian RNA polymerase II. J Biol Chem (1985) 3.11

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nat Cell Biol (2008) 3.08

Critical role for Daxx in regulating Mdm2. Nat Cell Biol (2006) 2.96

Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature (2004) 2.83

Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. Genes Dev (2007) 2.81

Functional domains of Epstein-Barr virus nuclear antigen EBNA-1. J Virol (1991) 2.63

Monoubiquitylation promotes mitochondrial p53 translocation. EMBO J (2007) 2.62

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev (2008) 2.48

Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus. EMBO J (2001) 2.46

Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway. PLoS Biol (2006) 2.35

H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Mol Cell (2007) 2.32

Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein, EBNA1, bound to DNA. Cell (1996) 2.25

GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Mol Cell (2005) 2.21

An EBNA-1-dependent enhancer acts from a distance of 10 kilobase pairs to increase expression of the Epstein-Barr virus LMP gene. J Virol (1995) 2.19

Host cell regulation of induction of Epstein-Barr virus. J Virol (1974) 2.19

The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression. Mol Cell (2004) 2.16

The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Nat Struct Biol (1996) 2.11

EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance. J Virol (1999) 2.07

Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of the nasopharynx. Int J Cancer (1980) 1.94

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol Cell (2005) 1.92

Nucleosomal structure of Epstein-Barr virus DNA in transformed cell lines. J Virol (1979) 1.91

Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA 1. Cell (1995) 1.87

P32/TAP, a cellular protein that interacts with EBNA-1 of Epstein-Barr virus. Virology (1997) 1.87

DNA looping between the origin of replication of Epstein-Barr virus and its enhancer site: stabilization of an origin complex with Epstein-Barr nuclear antigen 1. Proc Natl Acad Sci U S A (1991) 1.86

Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. J Biol Chem (2003) 1.78

Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus. Proc Natl Acad Sci U S A (1991) 1.66

Transcription start sites downstream of the Epstein-Barr virus (EBV) Fp promoter in early-passage Burkitt lymphoma cells define a fourth promoter for expression of the EBV EBNA-1 protein. J Virol (1996) 1.66

Sequence requirements of the Epstein-Barr virus latent origin of DNA replication. J Virol (1994) 1.64

Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. J Cell Sci (2003) 1.62

Separation of the complex DNA binding domain of EBNA-1 into DNA recognition and dimerization subdomains of novel structure. J Virol (1993) 1.55

Constitutive binding of EBNA1 protein to the Epstein-Barr virus replication origin, oriP, with distortion of DNA structure during latent infection. EMBO J (1993) 1.53

Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. J Biol Chem (2003) 1.47

Cell cycle regulation of chromatin at an origin of DNA replication. EMBO J (2005) 1.40

The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. J Virol (2008) 1.35

Chromatin profiling of Epstein-Barr virus latency control region. J Virol (2007) 1.34

Functional analyses of the EBNA1 origin DNA binding protein of Epstein-Barr virus. J Virol (2000) 1.33

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies. PLoS Pathog (2008) 1.31

Identification of EBNA1 amino acid sequences required for the interaction of the functional elements of the Epstein-Barr virus latent origin of DNA replication. J Virol (1993) 1.23

Role of EBNA-1 in arresting replication forks at the Epstein-Barr virus oriP family of tandem repeats. Mol Cell Biol (1991) 1.23

The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Traffic (2008) 1.22

The 2.2 A structure of a permanganate-sensitive DNA site bound by the Epstein-Barr virus origin binding protein, EBNA1. J Mol Biol (1998) 1.14

In vivo assays to study histone ubiquitylation. Methods (2003) 1.12

Human p32: a coactivator for Epstein-Barr virus nuclear antigen-1-mediated transcriptional activation and possible role in viral latent cycle DNA replication. Virology (2000) 1.10

Cooperative assembly of EBNA1 on the Epstein-Barr virus latent origin of replication. J Virol (1996) 1.08

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1. J Virol (2005) 1.06

Epstein-Barr virus episome stability is coupled to a delay in replication timing. J Virol (2008) 1.02

Two domains of the epstein-barr virus origin DNA-binding protein, EBNA1, orchestrate sequence-specific DNA binding. J Biol Chem (2000) 1.00

Role of the EBNA-1 protein in pausing of replication forks in the Epstein-Barr virus genome. J Biol Chem (1996) 0.96

Autorepression of Epstein-Barr virus nuclear antigen 1 expression by inhibition of pre-mRNA processing. J Virol (2007) 0.95

Mechanistic studies on the DNA linking activity of Epstein-Barr nuclear antigen 1. Nucleic Acids Res (1998) 0.95

Overexpression, purification, and crystallization of the DNA binding and dimerization domains of the Epstein-Barr virus nuclear antigen 1. J Biol Chem (1995) 0.89

Articles by these authors

The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. Nat Cell Biol (2010) 2.78

A transforming metal nanocomposite with large elastic strain, low modulus, and high strength. Science (2013) 2.28

Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional sperm. Cell Stem Cell (2012) 1.99

Molecular recognition of p53 and MDM2 by USP7/HAUSP. Nat Struct Mol Biol (2006) 1.97

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol Cell (2005) 1.92

Transcriptome sequencing and de novo analysis for Yesso scallop (Patinopecten yessoensis) using 454 GS FLX. PLoS One (2011) 1.86

Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. J Biol Chem (2003) 1.78

Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques. Stem Cells (2007) 1.65

Separation of the DNA replication, segregation, and transcriptional activation functions of Epstein-Barr nuclear antigen 1. J Virol (2002) 1.58

Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. J Biol Chem (2003) 1.47

Endotoxin tolerance of adrenal gland: attenuation of corticosterone production in response to lipopolysaccharide and adrenocorticotropic hormone. Crit Care Med (2011) 1.46

Transcriptome sequencing and characterization for the sea cucumber Apostichopus japonicus (Selenka, 1867). PLoS One (2012) 1.43

Viral proteomics. Microbiol Mol Biol Rev (2007) 1.43

Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis. Proc Natl Acad Sci U S A (2004) 1.40

The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4. J Virol (2008) 1.35

Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma. World J Gastroenterol (2004) 1.33

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies. PLoS Pathog (2008) 1.31

Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci (2010) 1.26

The influence of spheroid formation of human adipose-derived stem cells on chitosan films on stemness and differentiation capabilities. Biomaterials (2011) 1.25

Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE). Proc Biol Sci (2006) 1.24

Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. PLoS Pathog (2008) 1.20

Transcription factor FIGLA is mutated in patients with premature ovarian failure. Am J Hum Genet (2008) 1.20

Identification of transgelin-2 as a biomarker of colorectal cancer by laser capture microdissection and quantitative proteome analysis. Cancer Sci (2009) 1.19

EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis. World J Gastroenterol (2010) 1.19

EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases. Mol Cell Biol (2005) 1.19

The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population. J Affect Disord (2008) 1.17

The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins. J Biol Chem (2006) 1.17

Regulation of the EBNA1 Epstein-Barr virus protein by serine phosphorylation and arginine methylation. J Virol (2006) 1.16

cAMP response element-binding protein promotes gliomagenesis by modulating the expression of oncogenic microRNA-23a. Proc Natl Acad Sci U S A (2012) 1.15

EBNA1 partitions Epstein-Barr virus plasmids in yeast cells by attaching to human EBNA1-binding protein 2 on mitotic chromosomes. J Virol (2003) 1.11

[PLAC1/CP1 gene expression and autologous humoral immunity in gastric cancer patients]. Beijing Da Xue Xue Bao (2006) 1.09

CUL7 is a novel antiapoptotic oncogene. Cancer Res (2007) 1.09

Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodies. J Virol (2010) 1.08

Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. PLoS Genet (2013) 1.08

Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation. Cancer Res (2005) 1.06

Prevalence of heterotypic tumor/immune cell-in-cell structure in vitro and in vivo leading to formation of aneuploidy. PLoS One (2013) 1.05

Emperipolesis, entosis and beyond: dance with fate. Cell Res (2008) 1.05

Separating spermatogonia from cancer cells in contaminated prepubertal primate testis cell suspensions. Hum Reprod (2011) 1.05

MCM-BP regulates unloading of the MCM2-7 helicase in late S phase. Genes Dev (2010) 1.04

Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages. Cell Mol Life Sci (2010) 1.04

Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC. J Clin Invest (2014) 1.03

A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J Mol Biol (2005) 1.03

Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection. J Virol (2012) 1.03

Plac1 is a tumor-specific antigen capable of eliciting spontaneous antibody responses in human cancer patients. Int J Cancer (2008) 1.02

Identification and characterization of a novel component of the human minichromosome maintenance complex. Mol Cell Biol (2007) 1.02

Relationship between matrix metalloproteinase 2 and lung cancer progression. Mol Diagn Ther (2007) 1.02

Safety and efficacy of red yeast rice (Monascus purpureus) as an alternative therapy for hyperlipidemia. P T (2009) 1.02

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. J Exp Med (2012) 1.02

Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients. World J Gastroenterol (2008) 1.01

A miR-21 hairpin structure-based gene knockdown vector. Biochem Biophys Res Commun (2010) 1.01

Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response. J Virol (2011) 1.01

The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies. PLoS One (2011) 1.00

Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2. J Biol Chem (2010) 1.00

Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer. Int J Oncol (2010) 1.00

Identification of novel homologous microRNA genes in the rhesus macaque genome. BMC Genomics (2008) 1.00

The specific immune response to tumor antigen CP1 and its correlation with improved survival in colon cancer patients. Gastroenterology (2008) 0.99

Role of Pirh2 in mediating the regulation of p53 and c-Myc. PLoS Genet (2011) 0.99

Molecular characterization of vancomycin-resistant enterococcus faecium isolates from mainland China. J Clin Microbiol (2007) 0.99

Paxillin expression levels are correlated with clinical stage and metastasis in salivary adenoid cystic carcinoma. J Oral Pathol Med (2010) 0.98

Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways. Blood (2011) 0.98

Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis. Int J Mol Sci (2013) 0.97

Kindlin-2: a novel adhesion protein related to tumor invasion, lymph node metastasis, and patient outcome in gastric cancer. Am J Surg (2011) 0.96

Proteomic profiling of EBNA1-host protein interactions in latent and lytic Epstein-Barr virus infections. J Virol (2012) 0.96

Nucleosome assembly proteins bind to Epstein-Barr virus nuclear antigen 1 and affect its functions in DNA replication and transcriptional activation. J Virol (2009) 0.95

Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. Mol Cell Biol (2011) 0.94

Upregulation of the long noncoding RNA PCAT-1 correlates with advanced clinical stage and poor prognosis in esophageal squamous carcinoma. Tumour Biol (2015) 0.94

The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells. PLoS One (2012) 0.94

Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease. J Biol Chem (2013) 0.94

Mitotic chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human EBNA1-binding protein 2 (EBP2). J Cell Sci (2009) 0.94

Genotyping-by-sequencing (GBS) identified SNP tightly linked to QTL for pre-harvest sprouting resistance. Theor Appl Genet (2015) 0.93

Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface. J Biol Chem (2011) 0.93

MicroRNA-455 inhibits proliferation and invasion of colorectal cancer by targeting RAF proto-oncogene serine/threonine-protein kinase. Tumour Biol (2014) 0.92

MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway. Cell Cycle (2015) 0.92

DAPK1-p53 interaction converges necrotic and apoptotic pathways of ischemic neuronal death. J Neurosci (2014) 0.92

Evaluation of the seventh AJCC TNM staging system for gastric cancer: a meta-analysis of cohort studies. Tumour Biol (2014) 0.92

Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity. J Biol Chem (2010) 0.92

Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25): a multifunctional protein essential for spermatogenesis. J Androl (2009) 0.92

Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma. J Virol (2011) 0.92

FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS One (2013) 0.91

Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) gene: cell-specific expression and transcriptional regulation by androgen in transgenic mouse testis. J Cell Biochem (2010) 0.91

Genomic organization and transcriptional analysis of gonadotropin-regulated testicular RNA helicase--GRTH/DDX25 gene. Gene (2004) 0.91

Metabolic syndrome is an important factor for the evolution of prognosis of colorectal cancer: survival, recurrence, and liver metastasis. Am J Surg (2010) 0.91

Overexpression of microRNA-1 promotes cardiomyocyte commitment from human cardiovascular progenitors via suppressing WNT and FGF signaling pathways. J Mol Cell Cardiol (2013) 0.90

The size of mesenchymal stem cells is a significant cause of vascular obstructions and stroke. Stem Cell Rev (2014) 0.90

Effects of ovariectomy and 17beta-estradiol treatment on the renin-angiotensin system, blood pressure, and endothelial ultrastructure. Int J Cardiol (2008) 0.90

Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7. J Mol Biol (2010) 0.90

MARVELD1 inhibited cell proliferation and enhance chemosensitivity via increasing expression of p53 and p16 in hepatocellular carcinoma. Cancer Sci (2012) 0.90

Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function. Virology (2009) 0.89

Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer. World J Gastroenterol (2005) 0.89

EBNA1 efficiently assembles on chromatin containing the Epstein-Barr virus latent origin of replication. Virology (2003) 0.89

Clinicopathological significance of SIRT1 expression in colorectal adenocarcinoma. Med Oncol (2014) 0.89

MicroRNA-542-3p inhibits tumour angiogenesis by targeting angiopoietin-2. J Pathol (2014) 0.89

Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo. Mol Biol Rep (2008) 0.89

Novel focal adhesion protein kindlin-2 promotes the invasion of gastric cancer cells through phosphorylation of integrin β1 and β3. J Surg Oncol (2013) 0.89