Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure.

PubWeight™: 1.18‹?› | Rank: Top 10%

🔗 View Article (PMID 19839980)

Published in Allergy on October 14, 2009

Authors

M L A Schuttelaar1, M Kerkhof, M F Jonkman, G H Koppelman, B Brunekreef, J C de Jongste, A Wijga, W H I McLean, D S Postma

Author Affiliations

1: Departments of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Articles citing this

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet (2011) 3.03

One remarkable molecule: filaggrin. J Invest Dermatol (2011) 2.10

Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol (2013) 1.57

Skin barrier disruption: a requirement for allergen sensitization? J Invest Dermatol (2012) 1.40

Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases. J Clin Invest (2012) 1.38

Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosis. Clin Dev Immunol (2011) 1.21

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting. Nat Genet (2013) 1.17

Filaggrin gene mutation c.3321delA is associated with various clinical features of atopic dermatitis in the Chinese Han population. PLoS One (2014) 0.94

Early eczema and the risk of childhood asthma: a prospective, population-based study. BMC Pediatr (2012) 0.92

Skin barrier defects in atopic dermatitis. Curr Allergy Asthma Rep (2014) 0.91

Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age. PLoS One (2012) 0.90

Meta-analysis identifies seven susceptibility loci involved in the atopic march. Nat Commun (2015) 0.86

Context-specific protein network miner--an online system for exploring context-specific protein interaction networks from the literature. PLoS One (2012) 0.83

A meta-analysis of Th2 pathway genetic variants and risk for allergic rhinitis. Pediatr Allergy Immunol (2011) 0.81

Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence. J Allergy Clin Immunol (2014) 0.81

Vitamin d, the cutaneous barrier, antimicrobial peptides and allergies: is there a link? Allergy Asthma Immunol Res (2013) 0.80

Allergic sensitization and filaggrin variants predispose to the comorbidity of eczema, asthma, and rhinitis: results from the Isle of Wight birth cohort. Clin Exp Allergy (2014) 0.79

Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses: part II of a prospective cohort study. Contact Dermatitis (2013) 0.76

Association of filaggrin variants with asthma and rhinitis: is eczema or allergic sensitization status an effect modifier? Int Arch Allergy Immunol (2014) 0.75

Filaggrin gene mutations and new SNPs in asthmatic patients: a cross-sectional study in a Spanish population. Allergy Asthma Clin Immunol (2016) 0.75

Do early skin care practices alter the risk of atopic dermatitis? A case-control study. Pediatr Dermatol (2011) 0.75

Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI). BMJ Open (2017) 0.75

Articles by these authors

Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med (1997) 8.48

Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force. Eur Respir J (1995) 7.03

Inhaled disodium cromoglycate (DSCG) as maintenance therapy in children with asthma: a systematic review. Thorax (2000) 4.78

Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking. European Respiratory Society Study on Chronic Obstructive Pulmonary Disease. N Engl J Med (1999) 4.65

Motor vehicle exhaust and chronic respiratory symptoms in children living near freeways. Environ Res (1997) 4.29

Effects of inhaled fluticasone and oral prednisolone on clinical and inflammatory parameters in patients with asthma. Thorax (1999) 4.11

Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers. Eur Respir J (2005) 3.66

Personal sampling of particles in adults: relation among personal, indoor, and outdoor air concentrations. Am J Epidemiol (1998) 3.44

Air pollution and development of asthma, allergy and infections in a birth cohort. Eur Respir J (2007) 3.42

Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J (2008) 3.36

A new perspective on concepts of asthma severity and control. Eur Respir J (2008) 3.16

A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease. Dutch Chronic Non-Specific Lung Disease Study Group. N Engl J Med (1992) 3.13

The association between air pollution and heart failure, arrhythmia, embolism, thrombosis, and other cardiovascular causes of death in a time series study. Epidemiology (2001) 3.07

Long term effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a meta-analysis. Thorax (1999) 3.00

Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med (2016) 2.89

Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax (2004) 2.85

Chronic respiratory symptoms in children and adults living along streets with high traffic density. Occup Environ Med (1996) 2.71

Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease. Thorax (2005) 2.69

Comparison of formoterol and terbutaline for as-needed treatment of asthma: a randomised trial. Lancet (2001) 2.68

Traffic-related air pollution and respiratory health during the first 2 yrs of life. Eur Respir J (2002) 2.50

Decline in children's pulmonary function during an air pollution episode. J Air Pollut Control Assoc (1986) 2.47

Asthma at 8 years of age in children born by caesarean section. Thorax (2008) 2.45

Inappropriate use of daily mortality analyses to estimate longer-term mortality effects of air pollution. Int J Epidemiol (1998) 2.40

PC(20) adenosine 5'-monophosphate is more closely associated with airway inflammation in asthma than PC(20) methacholine. Am J Respir Crit Care Med (2001) 2.36

Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methods. Eur Respir J (2004) 2.36

Independent influence of reversibility of air-flow obstruction and nonspecific hyperreactivity on the long-term course of lung function in chronic air-flow obstruction. Am Rev Respir Dis (1986) 2.29

Can peak expiratory flow measurements reliably identify the presence of airway obstruction and bronchodilator response as assessed by FEV(1) in primary care patients presenting with a persistent cough? Thorax (1999) 2.25

Ciclesonide improves measures of small airway involvement in asthma. Eur Respir J (2008) 2.23

Randomised placebo-controlled trial of inhaled sodium cromoglycate in 1-4-year-old children with moderate asthma. Lancet (1997) 2.21

Severe exacerbations predict excess lung function decline in asthma. Eur Respir J (2007) 2.18

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17

Corticosteroid-induced improvement in the PC20 of adenosine monophosphate is more closely associated with reduction in airway inflammation than improvement in the PC20 of methacholine. Am J Respir Crit Care Med (2001) 2.08

Identifying asthma and chronic obstructive pulmonary disease in patients with persistent cough presenting to general practitioners: descriptive study. BMJ (1998) 2.08

A comparison between an outpatient hospital-based pulmonary rehabilitation program and a home-care pulmonary rehabilitation program in patients with COPD. A follow-up of 18 months. Chest (1996) 2.08

Exposure to traffic related air pollutants: self reported traffic intensity versus GIS modelled exposure. Occup Environ Med (2005) 2.07

Damp housing and childhood respiratory symptoms: the role of sensitization to dust mites and molds. Am J Epidemiol (1995) 2.06

Inhaled corticosteroids in COPD: a case in favour. Eur Respir J (2009) 2.06

The impact of smoking cessation on respiratory symptoms, lung function, airway hyperresponsiveness and inflammation. Eur Respir J (2004) 2.05

[Negative effects of passive smoking on the (unborn) child]. Ned Tijdschr Geneeskd (2002) 2.04

Decline of FEV1 by age and smoking status: facts, figures, and fallacies. Thorax (1997) 2.04

Estimation of long-term average exposure to outdoor air pollution for a cohort study on mortality. J Expo Anal Environ Epidemiol (2002) 2.04

Ongoing airway inflammation in patients with COPD who do not currently smoke. Thorax (2000) 2.02

Effect of ambient winter air pollution on respiratory health of children with chronic respiratory symptoms. Am Rev Respir Dis (1993) 2.00

Association of a promoter polymorphism of the CD14 gene and atopy. Am J Respir Crit Care Med (2001) 1.99

Interpretation of bronchodilator response in patients with obstructive airways disease. The Dutch Chronic Non-Specific Lung Disease (CNSLD) Study Group. Thorax (1992) 1.98

Revised classification system for inherited epidermolysis bullosa: Report of the Second International Consensus Meeting on diagnosis and classification of epidermolysis bullosa. J Am Acad Dermatol (2000) 1.97

Exacerbations of asthma: a descriptive study of 425 severe exacerbations. The FACET International Study Group. Am J Respir Crit Care Med (1999) 1.96

Effects of long-term treatment with corticosteroids in COPD. Chest (1996) 1.94

Home dampness and respiratory health status in european children. Clin Exp Allergy (1998) 1.92

Quality of life in patients with chronic obstructive pulmonary disease improves after rehabilitation at home. Eur Respir J (1994) 1.91

Childhood factors associated with asthma remission after 30 year follow up. Thorax (2004) 1.90

Anti-inflammatory effects of inhaled carbon monoxide in patients with COPD: a pilot study. Eur Respir J (2007) 1.90

Childhood asthma and the indoor environment. Chest (1991) 1.85

Reliability and validity of the chronic respiratory questionnaire (CRQ). Thorax (1994) 1.84

Filaggrin loss-of-function mutations are associated with early-onset eczema, eczema severity and transepidermal water loss at 3 months of age. Br J Dermatol (2010) 1.81

Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics (1994) 1.81

International consensus on (ICON) pediatric asthma. Allergy (2012) 1.79

Histamine airway hyper-responsiveness and mortality from chronic obstructive pulmonary disease: a cohort study. Lancet (2000) 1.78

Inverse association of farm milk consumption with asthma and allergy in rural and suburban populations across Europe. Clin Exp Allergy (2007) 1.78

Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis. Br J Dermatol (2011) 1.77

Adverse health effects of prenatal and postnatal tobacco smoke exposure on children. Arch Dis Child (2003) 1.77

Genome-wide association study of body mass index in 23 000 individuals with and without asthma. Clin Exp Allergy (2013) 1.74

Variability of exposure measurements in environmental epidemiology. Am J Epidemiol (1987) 1.73

Association of consumption of products containing milk fat with reduced asthma risk in pre-school children: the PIAMA birth cohort study. Thorax (2003) 1.72

Primary pulmonary hypertension in a patient with systemic lupus erythematosus: partial improvement with cyclophosphamide. J Rheumatol (1993) 1.71

Simulating an integrated critiquing system. J Am Med Inform Assoc (1998) 1.71

Prolonged protection of the new inhaled corticosteroid fluticasone furoate against AMP hyperresponsiveness in patients with asthma. Allergy (2010) 1.70

Measurement of exhaled nitric oxide in children, 2001. Eur Respir J (2002) 1.69

Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. Am J Respir Cell Mol Biol (2001) 1.65

Acute effects of a winter air pollution episode on pulmonary function and respiratory symptoms of children. Arch Environ Health (1993) 1.65

Influence of the parasympathetic and sympathetic nervous system on nocturnal bronchial obstruction. Clin Sci (Lond) (1985) 1.64

Major genes regulating total serum immunoglobulin E levels in families with asthma. Am J Hum Genet (2000) 1.63

Daily mortality and air pollution in The Netherlands. J Air Waste Manag Assoc (2000) 1.63

The joint association of air pollution and noise from road traffic with cardiovascular mortality in a cohort study. Occup Environ Med (2008) 1.63

Personal exposure to fine particulate matter in elderly subjects: relation between personal, indoor, and outdoor concentrations. J Air Waste Manag Assoc (2000) 1.63

Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a randomised controlled trial. Thorax (2005) 1.62

Exhaled nitric oxide in 4-year-old children: relationship with asthma and atopy. Eur Respir J (2005) 1.62

Daily variations in air pollution and respiratory health in a multicentre study: the PEACE project. Pollution Effects on Asthmatic Children in Europe. Eur Respir J (1998) 1.62

Relation between airborne pollen concentrations and daily cardiovascular and respiratory-disease mortality. Lancet (2000) 1.61

Relation between duration of smoking cessation and bronchial inflammation in COPD. Thorax (2005) 1.60

No effects of high-dose omeprazole in patients with severe airway hyperresponsiveness and (a)symptomatic gastro-oesophageal reflux. Eur Respir J (1998) 1.60

Skin sensitivity to UVB irradiation in systemic lupus erythematosus is not related to the level of apoptosis induction in keratinocytes. Rheumatology (Oxford) (2005) 1.59

Particle size matters: diagnostics and treatment of small airways involvement in asthma. Eur Respir J (2010) 1.58

The ultrastructure of acantholysis in pemphigus vulgaris. Br J Dermatol (2008) 1.58

Childhood exposure to PM10: relation between personal, classroom, and outdoor concentrations. Occup Environ Med (1997) 1.58

Early, current and past pet ownership: associations with sensitization, bronchial responsiveness and allergic symptoms in school children. Clin Exp Allergy (2002) 1.57