Published in Curr Genomics on May 01, 2009
Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage. J Neurosci (2011) 2.25
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene (2010) 1.97
Epigenetics meets endocrinology. J Mol Endocrinol (2011) 1.30
miRNAs and estrogen action. Trends Endocrinol Metab (2012) 1.24
Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis. J Biol Chem (2010) 1.18
SNPing cancer in the bud: microRNA and microRNA-target site polymorphisms as diagnostic and prognostic biomarkers in cancer. Pharmacol Ther (2012) 1.18
Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer. Cancer Res (2010) 1.12
Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells. BMC Cancer (2012) 1.02
Derailed estrogen signaling and breast cancer: an authentic couple. Endocr Rev (2012) 1.01
Epigenomics, gestational programming and risk of metabolic syndrome. Int J Obes (Lond) (2015) 0.99
miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets. Mol Cell Endocrinol (2015) 0.94
Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer. Mol Cell Endocrinol (2012) 0.92
Differential expression of microRNA expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. Cancer Lett (2011) 0.92
Overexpression of microRNA-200c predicts poor outcome in patients with PR-negative breast cancer. PLoS One (2014) 0.90
Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription. Mol Cell Endocrinol (2010) 0.89
Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies? J Biomed Biotechnol (2010) 0.86
Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer. Cancer Res (2014) 0.86
Chemopreventive and therapeutic activity of dietary blueberry against estrogen-mediated breast cancer. J Agric Food Chem (2014) 0.82
Urinary MicroRNA Profiling Predicts the Development of Microalbuminuria in Patients with Type 1 Diabetes. J Clin Med (2015) 0.82
Sexually dimorphic effects of gestational endocrine-disrupting chemicals on microRNA expression in the developing rat hypothalamus. Mol Cell Endocrinol (2015) 0.79
Expression of the Mir-133 and Bcl-2 could be affected by swimming training in the heart of ovariectomized rats. Iran J Basic Med Sci (2016) 0.78
Variation among rainbow trout (Oncorhynchus mykiss) estrogen receptor isoform 3' untranslated regions and the effect of 17beta-estradiol on mRNA stability in hepatocyte culture. DNA Cell Biol (2010) 0.77
Is timing everything? New insights into why the effect of estrogen therapy on memory might be age dependent. Endocrinology (2013) 0.76
Sex, epilepsy, and epigenetics. Neurobiol Dis (2014) 0.75
Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis. Sci Rep (2017) 0.75
Therapeutic microRNA-based strategies in cardiovascular disease discriminate sex and age difference. J Physiol (2016) 0.75
miR-639 promotes the proliferation and invasion of breast cancer cell in vitro. Cancer Cell Int (2014) 0.75
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09
Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2008) 37.16
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
MicroRNA gene expression deregulation in human breast cancer. Cancer Res (2005) 27.56
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol (2008) 24.27
miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A (2005) 21.51
Genome-wide analysis of estrogen receptor binding sites. Nat Genet (2006) 18.63
RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science (2007) 18.59
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res (2005) 18.58
Switching from repression to activation: microRNAs can up-regulate translation. Science (2007) 17.00
Endogenous human microRNAs that suppress breast cancer metastasis. Nature (2008) 14.37
let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell (2007) 13.69
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology (2007) 13.20
Regulation of the germinal center response by microRNA-155. Science (2007) 12.25
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell (2000) 11.10
Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res (2005) 10.46
Ribo-gnome: the big world of small RNAs. Science (2005) 10.10
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell (1998) 9.96
miR-21-mediated tumor growth. Oncogene (2006) 9.90
A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science (2005) 9.80
The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res (2007) 9.32
microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci U S A (2006) 8.24
Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev (1999) 7.42
MicroRNA-cancer connection: the beginning of a new tale. Cancer Res (2006) 7.38
A microRNA signature of hypoxia. Mol Cell Biol (2006) 7.24
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. Science (1997) 6.60
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res (2007) 6.57
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol (2007) 6.43
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol (2007) 6.41
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev (2006) 6.32
Molecular determinants for the tissue specificity of SERMs. Science (2002) 6.20
Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genet (2007) 5.85
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res (2007) 5.62
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer (2006) 5.47
Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res (2005) 5.44
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res (2007) 5.40
The eukaryotic genome as an RNA machine. Science (2008) 5.29
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res (2007) 5.25
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res (2007) 5.25
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology (2004) 5.20
Genomic analysis of human microRNA transcripts. Proc Natl Acad Sci U S A (2007) 5.20
An E2F/miR-20a autoregulatory feedback loop. J Biol Chem (2006) 5.20
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res (2007) 4.95
MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol (2008) 4.76
Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. Cancer Res (2007) 4.65
Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem (2006) 4.59
Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem (2006) 4.57
MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem (2008) 4.56
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene (2008) 4.43
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene (2007) 4.41
MicroRNA silencing through RISC recruitment of eIF6. Nature (2007) 4.37
MicroRNAs: a developing story. Curr Opin Genet Dev (2005) 4.34
Estrogen receptor interaction with estrogen response elements. Nucleic Acids Res (2001) 4.23
Hormonal carcinogenesis. Carcinogenesis (2000) 3.86
Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev (2004) 3.74
Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol (2006) 3.71
Retracted MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem (2008) 3.63
Integration of the extranuclear and nuclear actions of estrogen. Mol Endocrinol (2005) 3.44
Nuclear receptor coactivators and corepressors. Mol Endocrinol (1996) 3.44
The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res (2007) 3.40
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol (2007) 3.39
The endocrinology of aging. Science (1997) 3.28
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem (2001) 3.24
miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res (2008) 3.19
Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol Cell (2007) 3.18
Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc Natl Acad Sci U S A (2008) 3.08
Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature (1977) 3.04
A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol (2008) 3.02
Nature of functional estrogen receptors at the plasma membrane. Mol Endocrinol (2006) 2.90
Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res (2006) 2.83
The Argonaute protein family. Genome Biol (2008) 2.83
miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res (2008) 2.80
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene (2007) 2.79
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol (2001) 2.76
Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci U S A (1998) 2.68
Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing. Cancer Res (2006) 2.59
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. Cancer Res (2001) 2.50
Resurrecting the ancestral steroid receptor: ancient origin of estrogen signaling. Science (2003) 2.49
Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol Endocrinol (1997) 2.42
Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions. Proc Natl Acad Sci U S A (2001) 2.38
A conserved mechanism for steroid receptor translocation to the plasma membrane. J Biol Chem (2007) 2.34
Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem (2002) 2.31
Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane. Endocrinology (2007) 2.29
The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition. Genome Biol (2008) 2.29
Principles of micro-RNA production and maturation. Oncogene (2006) 2.27
Retracted Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids. J Cell Mol Med (2007) 2.24
Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc Natl Acad Sci U S A (2003) 2.22
ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol Endocrinol (2002) 2.20
Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane. Mol Cell Biol (2003) 2.19
Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation. Mol Endocrinol (2002) 2.18
Retracted The expression profile of micro-RNA in endometrium and endometriosis and the influence of ovarian steroids on their expression. Mol Hum Reprod (2007) 2.18
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption. J Steroid Biochem Mol Biol (2006) 2.17
Estrogen receptor phosphorylation. Steroids (2003) 2.17
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters. Proc Natl Acad Sci U S A (2007) 2.17
MicroRNA regulates the expression of human cytochrome P450 1B1. Cancer Res (2006) 2.16
A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA (2008) 2.16
The role of corepressors in transcriptional regulation by nuclear hormone receptors. Annu Rev Physiol (2004) 2.14