Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 2785126)

Published in Clin Cancer Res on November 10, 2009

Authors

Urszula Dougherty1, Dario Cerasi, Ieva Taylor, Masha Kocherginsky, Ummuhan Tekin, Shamiram Badal, Lata Aluri, Amikar Sehdev, Sonia Cerda, Reba Mustafi, Jorge Delgado, Loren Joseph, Hongyan Zhu, John Hart, David Threadgill, Alessandro Fichera, Marc Bissonnette

Author Affiliations

1: Departments of Medicine, Health Studies, Surgery, and Pathology, University of Chicago, Chicago, Illinois , USA.

Articles citing this

EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators. Mol Cancer Res (2011) 1.18

MicroRNA, nutrition, and cancer prevention. Adv Nutr (2011) 1.02

Epidermal growth factor receptor inhibits colitis-associated cancer in mice. J Clin Invest (2012) 1.01

Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas. Oncogene (2010) 0.99

American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR. BMC Complement Altern Med (2011) 0.98

Colon cancer and the epidermal growth factor receptor: Current treatment paradigms, the importance of diet, and the role of chemoprevention. World J Clin Oncol (2015) 0.84

Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts. Carcinogenesis (2012) 0.80

Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia. Mol Cancer (2014) 0.79

The renin-angiotensin system mediates EGF receptor-vitamin d receptor cross-talk in colitis-associated colon cancer. Clin Cancer Res (2014) 0.77

ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer. Clin Cancer Res (2016) 0.75

Linking Diet to Colorectal Cancer: The Emerging Role of MicroRNA in the Communication between Plant and Animal Kingdoms. Front Microbiol (2017) 0.75

Articles cited by this

Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08

Identification of c-MYC as a target of the APC pathway. Science (1998) 24.25

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature (1999) 20.34

Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer (2008) 11.50

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A (1999) 10.75

Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest (1993) 10.09

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology (1994) 8.79

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell (1996) 7.46

Statistical analysis of real-time PCR data. BMC Bioinformatics (2006) 7.31

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science (1995) 6.58

Myc deletion rescues Apc deficiency in the small intestine. Nature (2007) 5.42

Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States. J Natl Cancer Inst (1968) 4.68

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol (1994) 4.46

Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology (2003) 4.10

Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine. Gastroenterology (2006) 2.78

Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci U S A (2002) 2.65

Colorectal cancer incidence in the United States, 1999-2004 : an updated analysis of data from the National Program of Cancer Registries and the Surveillance, Epidemiology, and End Results Program. Cancer (2009) 2.26

Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature. J Clin Gastroenterol (2005) 2.08

A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice. Carcinogenesis (2001) 1.99

Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways. Cancer Res (2003) 1.97

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation. Proc Natl Acad Sci U S A (1995) 1.95

Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res (2000) 1.88

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol (2004) 1.80

The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer (1994) 1.71

Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice. Carcinogenesis (2005) 1.65

Dietary induction of colonic tumors in a mouse model of sporadic colon cancer. Cancer Res (2008) 1.58

Statistical methods for the analysis of tumor multiplicity data. Cancer Res (1981) 1.53

Dietary factors in human colorectal cancer. Annu Rev Nutr (1999) 1.42

Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids. Cancer Res (2001) 1.41

Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps. Cancer Res (2002) 1.39

HDAC6 is required for epidermal growth factor-induced beta-catenin nuclear localization. J Biol Chem (2008) 1.31

Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid. Cancer Res (1994) 1.25

K-Ras-mediated increase in cyclooxygenase 2 mRNA stability involves activation of the protein kinase B1. Cancer Res (2001) 1.22

Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model. Clin Cancer Res (2008) 1.21

A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model. J Surg Res (2007) 1.17

Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells. J Nutr (2004) 1.16

Dietary fat and colon cancer: modulation of cyclooxygenase-2 by types and amount of dietary fat during the postinitiation stage of colon carcinogenesis. Cancer Res (1997) 1.13

Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms. Genomics (2001) 1.08

Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis. Cancer Res (2007) 1.07

Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I. Mol Endocrinol (2004) 1.00

Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1. Cancer Res (2000) 0.97

Effect of type and amount of dietary fat and 1,2-dimethylhydrazine on biliary bile acids, fecal bile acids, and neutral sterols in rats. Cancer Res (1977) 0.96

The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis. Cancer Res (2005) 0.94

Ligand-dependent activation of the epidermal growth factor receptor by secondary bile acids in polarizing colon cancer cells. Surgery (2005) 0.88

Long-term feeding of various fat diets modulates azoxymethane-induced colon carcinogenesis through Wnt/beta-catenin signaling in rats. Am J Physiol Gastrointest Liver Physiol (2006) 0.88

beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet. Cancer Sci (2008) 0.85

A high-fat diet generates alterations in nuclear receptor expression: prevention by vitamin A and links with cyclooxygenase-2 and beta-catenin. Int J Cancer (2005) 0.83

Effect of bile acids and dietary fat on large bowel carcinogenesis in animal models. Gastroenterol Jpn (1978) 0.79

Articles by these authors

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet (2006) 15.63

The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet (2007) 5.09

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol (2004) 5.06

Averting biodiversity collapse in tropical forest protected areas. Nature (2012) 4.46

Abnormal placentation: twenty-year analysis. Am J Obstet Gynecol (2005) 3.88

Forest elephant crisis in the Congo Basin. PLoS Biol (2007) 3.74

Estimating genome conservation between crop and model legume species. Proc Natl Acad Sci U S A (2004) 3.55

Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25

Distinct prefrontal cortex activity associated with item memory and source memory for visual shapes. Brain Res Cogn Brain Res (2003) 3.14

Investigation of the cause of death in a gene-therapy trial. N Engl J Med (2009) 3.02

The use and interpretation of competing risks regression models. Clin Cancer Res (2012) 3.01

Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process. Gastroenterology (2012) 2.68

Complete Barrett's eradication endoscopic mucosal resection: an effective treatment modality for high-grade dysplasia and intramucosal carcinoma--an American single-center experience. Am J Gastroenterol (2009) 2.66

Conservation. Elephants, ivory, and trade. Science (2010) 2.51

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier. Am J Physiol Gastrointest Liver Physiol (2007) 2.45

Liver autoimmunity triggered by microbial activation of natural killer T cells. Cell Host Microbe (2008) 2.30

Surface area congruence of atlas superior articulating facets and occipital condyles. J Chiropr Med (2008) 2.29

Devastating decline of forest elephants in central Africa. PLoS One (2013) 2.28

Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows. Bioinformatics (2007) 2.17

R gene-controlled host specificity in the legume-rhizobia symbiosis. Proc Natl Acad Sci U S A (2010) 2.10

The Lung Image Database Consortium (LIDC): an evaluation of radiologist variability in the identification of lung nodules on CT scans. Acad Radiol (2007) 2.06

A systematic review of the quality of randomized controlled trials in head and neck oncology surgery. Laryngoscope (2014) 2.01

Identification and characterization of nucleotide-binding site-leucine-rich repeat genes in the model plant Medicago truncatula. Plant Physiol (2007) 2.01

Gastric mucosal necrosis with vascular degeneration induced by doxycycline. Am J Surg Pathol (2013) 1.99

Dexamethasone decreases xenograft response to Paclitaxel through inhibition of tumor cell apoptosis. Cancer Biol Ther (2006) 1.92

Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res (2005) 1.90

The influence of carbon dioxide on brain activity and metabolism in conscious humans. J Cereb Blood Flow Metab (2010) 1.88

Depressive symptoms and white matter dysfunction in retired NFL players with concussion history. Neurology (2013) 1.87

Electron paramagnetic resonance oxygen image hypoxic fraction plus radiation dose strongly correlates with tumor cure in FSa fibrosarcomas. Int J Radiat Oncol Biol Phys (2008) 1.84

Diversity, distribution, and ancient taxonomic relationships within the TIR and non-TIR NBS-LRR resistance gene subfamilies. J Mol Evol (2002) 1.77

Integration of novel SSR and gene-based SNP marker loci in the chickpea genetic map and establishment of new anchor points with Medicago truncatula genome. Theor Appl Genet (2010) 1.76

First assessment of needle-based confocal laser endomicroscopy during EUS-FNA procedures of the pancreas (with videos). Gastrointest Endosc (2011) 1.72

Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J Mol Cell Cardiol (2010) 1.66

Bowel necrosis associated with early jejunal tube feeding: A complication of postoperative enteral nutrition. Arch Surg (2006) 1.65

Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients. Clin Cancer Res (2012) 1.63

Brain activity in adolescent major depressive disorder before and after fluoxetine treatment. Am J Psychiatry (2012) 1.61

Role of 4-1BB in allograft rejection mediated by CD8+ T cells. Am J Transplant (2003) 1.61

Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease. Leuk Lymphoma (2010) 1.55

Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions. Blood (2011) 1.55

A case of adult hepatic toxocariasis. Nat Clin Pract Gastroenterol Hepatol (2008) 1.51

InvertNet: a new paradigm for digital access to invertebrate collections. Zookeys (2012) 1.50

Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling. Genes Dev (2004) 1.46

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons. Proc Natl Acad Sci U S A (2009) 1.45

Performance status and comorbidity predict transplant-related mortality after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant (2006) 1.44

A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle. Cancer Res (2009) 1.43

A pilot study of in vivo identification of pancreatic cystic neoplasms with needle-based confocal laser endomicroscopy under endosonographic guidance. Endoscopy (2013) 1.42

Natural history of mucinous ductal ectasia of the pancreas: a case report and review of the literature. Am J Gastroenterol (2002) 1.42

Long-term functional results after ileal pouch anal restorative proctocolectomy for ulcerative colitis: a prospective observational study. Ann Surg (2003) 1.40

Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer. Cancer Res (2011) 1.40

Intravenous regional anesthesia administered by the operating plastic surgeon: is it safe and efficient? Experience of a medical center. Plast Reconstr Surg (2007) 1.38

Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis. J Clin Invest (2013) 1.38

Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer. Clin Cancer Res (2013) 1.31

Influence of ethnicity on histological differences in non-alcoholic fatty liver disease. J Hepatol (2009) 1.29

Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor (GIST). Int J Colorectal Dis (2006) 1.28

Measurement of mesothelioma on thoracic CT scans: a comparison of manual and computer-assisted techniques. Med Phys (2004) 1.27

Liver biopsy interpretation for causes of late liver allograft dysfunction. Hepatology (2006) 1.24

Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer. J Clin Oncol (2008) 1.23

Assessment of radiologist performance in the detection of lung nodules: dependence on the definition of "truth". Acad Radiol (2009) 1.23

Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7. Cancer Res (2005) 1.21

Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension. Mol Cancer Ther (2004) 1.21

Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model. Clin Cancer Res (2008) 1.21

miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. Inflamm Bowel Dis (2011) 1.20

The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer. PLoS One (2011) 1.20

Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase. Cancer Res (2006) 1.20

Correlation between academic performance and NBCE part I scores at a chiropractic college. J Chiropr Educ (2013) 1.19

Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial. Clin Cancer Res (2013) 1.19

EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators. Mol Cancer Res (2011) 1.18

A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model. J Surg Res (2007) 1.17

Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study. Clin Gastroenterol Hepatol (2013) 1.17

CD95 signaling deficient mice with a wild-type hematopoietic system are prone to hepatic neoplasia. Apoptosis (2008) 1.17

BNip3 regulates mitochondrial function and lipid metabolism in the liver. Mol Cell Biol (2012) 1.17

Symbiosis specificity in the legume: rhizobial mutualism. Cell Microbiol (2012) 1.15

Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer. Int J Oncol (2012) 1.15