Published in Metab Eng on December 21, 2009
Successful high-level accumulation of fish oil omega-3 long-chain polyunsaturated fatty acids in a transgenic oilseed crop. Plant J (2013) 1.62
Biofuels from algae: challenges and potential. Biofuels (2010) 1.54
Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica. Nat Biotechnol (2013) 1.38
Metabolic engineering plant seeds with fish oil-like levels of DHA. PLoS One (2012) 1.33
Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production. Microb Cell Fact (2012) 1.29
Reconstitution of EPA and DHA biosynthesis in arabidopsis: iterative metabolic engineering for the synthesis of n-3 LC-PUFAs in transgenic plants. Metab Eng (2013) 1.26
Readily available sources of long-chain omega-3 oils: is farmed Australian seafood a better source of the good oil than wild-caught seafood? Nutrients (2014) 1.24
Long-chain omega-3 oils-an update on sustainable sources. Nutrients (2010) 1.05
Metabolic engineering of Phaeodactylum tricornutum for the enhanced accumulation of omega-3 long chain polyunsaturated fatty acids. Metab Eng (2013) 1.04
Expanding the docosahexaenoic acid food web for sustainable production: engineering lower plant pathways into higher plants. AoB Plants (2011) 0.93
Pathways of lipid metabolism in marine algae, co-expression network, bottlenecks and candidate genes for enhanced production of EPA and DHA in species of Chromista. Mar Drugs (2013) 0.91
DHA-containing oilseed: a timely solution for the sustainability issues surrounding fish oil sources of the health-benefitting long-chain omega-3 oils. Nutrients (2014) 0.91
Identification and characterization of new Δ-17 fatty acid desaturases. Appl Microbiol Biotechnol (2012) 0.87
Transgenic plants as a sustainable, terrestrial source of fish oils. Eur J Lipid Sci Technol (2015) 0.86
Modifying the lipid content and composition of plant seeds: engineering the production of LC-PUFA. Appl Microbiol Biotechnol (2014) 0.84
Transcriptional transitions in Nicotiana benthamiana leaves upon induction of oil synthesis by WRINKLED1 homologs from diverse species and tissues. BMC Plant Biol (2015) 0.84
Synthetic redesign of plant lipid metabolism. Plant J (2016) 0.80
Effects of long chain fatty acid synthesis and associated gene expression in microalga Tetraselmis sp. Mar Drugs (2014) 0.78
Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla. J Lipid Res (2015) 0.78
Identification and functional characterization of genes encoding omega-3 polyunsaturated fatty acid biosynthetic activities from unicellular microalgae. Mar Drugs (2013) 0.76
Classification and substrate head-group specificity of membrane fatty acid desaturases. Comput Struct Biotechnol J (2016) 0.75
Application of a delta-6 desaturase with α-linolenic acid preference on eicosapentaenoic acid production in Mortierella alpina. Microb Cell Fact (2016) 0.75
Reduced Triacylglycerol Mobilization during Seed Germination and Early Seedling Growth in Arabidopsis Containing Nutritionally Important Polyunsaturated Fatty Acids. Front Plant Sci (2016) 0.75
Towards the development of a sustainable soya bean-based feedstock for aquaculture. Plant Biotechnol J (2016) 0.75
Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids. Biomed Res Int (2017) 0.75
Molecular Characterization of Two Lysophospholipid:acyl-CoA Acyltransferases Belonging to the MBOAT Family in Nicotiana benthamiana. PLoS One (2015) 0.75
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
Innovative approaches for designing and analyzing adaptive dose-ranging trials. J Biopharm Stat (2007) 4.78
Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL). Hepatol Int (2008) 4.16
Feeding aquaculture in an era of finite resources. Proc Natl Acad Sci U S A (2009) 4.11
Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer. Proc Natl Acad Sci U S A (2007) 3.84
Trends in incidence and mortality of nasopharyngeal carcinoma over a 20-25 year period (1978/1983-2002) in Sihui and Cangwu counties in southern China. BMC Cancer (2006) 2.71
Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration. Neuron (2003) 2.51
Physics. Learning and scientific reasoning. Science (2009) 2.49
Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway. Blood (2009) 2.39
rRNA modifications in an intersubunit bridge of the ribosome strongly affect both ribosome biogenesis and activity. Mol Cell (2007) 1.95
Strigolactones are transported through the xylem and play a key role in shoot architectural response to phosphate deficiency in nonarbuscular mycorrhizal host Arabidopsis. Plant Physiol (2010) 1.89
The clinical and radiological spectrum of posterior reversible encephalopathy syndrome: a retrospective series of 24 patients. J Neuroimaging (2010) 1.88
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science (2012) 1.84
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Gastroenterology (2013) 1.83
A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide. Proc Natl Acad Sci U S A (2009) 1.83
Critical role of CXC chemokines in endotoxemic liver injury in mice. J Leukoc Biol (2003) 1.79
Nonredundant functions of Kinesin-13s during meiotic spindle assembly. Curr Biol (2007) 1.69
The role of concurrent chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal carcinoma among endemic population: a meta-analysis of the phase III randomized trials. BMC Cancer (2010) 1.68
Chemical characterization of exopolysaccharides from Antarctic marine bacteria. Microb Ecol (2005) 1.58
Gaining confidence in biological interpretation of the microarray data: the functional consistence of the significant GO categories. Bioinformatics (2007) 1.50
Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases. Mol Ther (2013) 1.49
Functional significance of CD14 promoter polymorphisms and their clinical relevance in a Chinese Han population. Crit Care Med (2008) 1.49
Stable isotope and signature fatty acid analyses suggest reef manta rays feed on demersal zooplankton. PLoS One (2013) 1.48
A Comparative Assessment of Observational Medical Outcomes Partnership and Mini-Sentinel Common Data Models and Analytics: Implications for Active Drug Safety Surveillance. Drug Saf (2015) 1.45
A leaf-based assay using interchangeable design principles to rapidly assemble multistep recombinant pathways. Plant Biotechnol J (2009) 1.44
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice. Proc Natl Acad Sci U S A (2007) 1.43
Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma. Arch Surg (2009) 1.42
Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing. RNA (2009) 1.41
Interannual and between species comparison of the lipids, fatty acids and sterols of Antarctic krill from the US AMLR Elephant Island survey area. Comp Biochem Physiol B Biochem Mol Biol (2002) 1.33
Metabolic engineering plant seeds with fish oil-like levels of DHA. PLoS One (2012) 1.33
Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis. Nat Genet (2009) 1.31
Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA. ACS Nano (2012) 1.30
Effect of deletion of genes involved in lipopolysaccharide core and O-antigen synthesis on virulence and immunogenicity of Salmonella enterica serovar typhimurium. Infect Immun (2011) 1.30
An epidemiological and molecular study of the relationship between smoking, risk of nasopharyngeal carcinoma, and Epstein-Barr virus activation. J Natl Cancer Inst (2012) 1.29
Evaluating reproducibility of differential expression discoveries in microarray studies by considering correlated molecular changes. Bioinformatics (2009) 1.29
Replacement of dietary fish oil for Atlantic salmon parr (Salmo salar L.) with a stearidonic acid containing oil has no effect on omega-3 long-chain polyunsaturated fatty acid concentrations. Comp Biochem Physiol B Biochem Mol Biol (2006) 1.29
Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells. Mol Cell Biol (2007) 1.27
Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J Biol Chem (2005) 1.26
High-stearic and High-oleic cottonseed oils produced by hairpin RNA-mediated post-transcriptional gene silencing. Plant Physiol (2002) 1.26
n-3 Oil sources for use in aquaculture--alternatives to the unsustainable harvest of wild fish. Nutr Res Rev (2008) 1.26
You are what you eat: describing the foraging ecology of southern elephant seals (Mirounga leonina) using blubber fatty acids. Proc Biol Sci (2003) 1.25
The cathepsin B of Toxoplasma gondii, toxopain-1, is critical for parasite invasion and rhoptry protein processing. J Biol Chem (2002) 1.24
Isocyanate vapor-induced antigenicity of human albumin. J Allergy Clin Immunol (2004) 1.24
Eight-signature classifier for prediction of nasopharyngeal [corrected] carcinoma survival. J Clin Oncol (2011) 1.23
Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss. Blood (2009) 1.23
Metabolic engineering of biomass for high energy density: oilseed-like triacylglycerol yields from plant leaves. Plant Biotechnol J (2013) 1.23
Fluctuations of epstein-barr virus serological antibodies and risk for nasopharyngeal carcinoma: a prospective screening study with a 20-year follow-up. PLoS One (2011) 1.22
GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins. J Biol Chem (2006) 1.22
hpRNA-mediated targeting of the Arabidopsis FAD2 gene gives highly efficient and stable silencing. Plant Physiol (2002) 1.20
Benign pathological findings in 303 Chinese patients undergoing surgery for presumed localized renal cell carcinoma. Int J Urol (2010) 1.20
Overexpression of microRNA OsmiR397 improves rice yield by increasing grain size and promoting panicle branching. Nat Biotechnol (2013) 1.20
Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PLoS One (2011) 1.19
An evaluation of the THIN database in the OMOP Common Data Model for active drug safety surveillance. Drug Saf (2013) 1.18
Synergistic effect of WRI1 and DGAT1 coexpression on triacylglycerol biosynthesis in plants. FEBS Lett (2013) 1.17
Prevalence of psoriasis in China: a population-based study in six cities. Eur J Dermatol (2012) 1.17
Metabolic engineering of plant oils and waxes for use as industrial feedstocks. Plant Biotechnol J (2012) 1.16
Salmonella synthesizing 1-dephosphorylated [corrected] lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity. J Immunol (2011) 1.15
Primate-specific miR-663 functions as a tumor suppressor by targeting PIK3CD and predicts the prognosis of human glioblastoma. Clin Cancer Res (2014) 1.15
Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia. Am J Hum Genet (2009) 1.12
Biodiscovery of new Australian thraustochytrids for production of biodiesel and long-chain omega-3 oils. Appl Microbiol Biotechnol (2012) 1.12
Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. BMC Genomics (2009) 1.10
Comparison of 6th and 7th AJCC TNM staging classification for carcinoma of the stomach in China. Ann Surg Oncol (2011) 1.10
β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma. Cancer Res (2013) 1.08
A large and functionally diverse family of Fad2 genes in safflower (Carthamus tinctorius L.). BMC Plant Biol (2013) 1.08
Vertical stratification of fatty acids in the blubber of southern elephant seals (Mirounga leonina): implications for diet analysis. Comp Biochem Physiol B Biochem Mol Biol (2003) 1.08
Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma. Cancer Sci (2009) 1.07
Small nucleolar RNA interference induced by antisense or double-stranded RNA in trypanosomatids. Proc Natl Acad Sci U S A (2003) 1.06
Metformin vs insulin in the management of gestational diabetes: a meta-analysis. PLoS One (2013) 1.05
Passive smoking and preterm birth in urban China. Am J Epidemiol (2014) 1.05
CDNA-AFLP combined with functional analysis reveals novel genes involved in the hypersensitive response. Mol Plant Microbe Interact (2006) 1.05
Signal-dependent regulation of transcription by histone deacetylase 7 involves recruitment to promyelocytic leukemia protein nuclear bodies. Mol Biol Cell (2008) 1.05
Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome. Am J Hum Genet (2007) 1.05
Two Epstein-Barr virus-related serologic antibody tests in nasopharyngeal carcinoma screening: results from the initial phase of a cluster randomized controlled trial in Southern China. Am J Epidemiol (2012) 1.04
A family of aspartic proteases and a novel, dynamic and cell-cycle-dependent protease localization in the secretory pathway of Toxoplasma gondii. Traffic (2007) 1.04
Mobilization of arachidonyl moieties from triacylglycerols into chloroplastic lipids following recovery from nitrogen starvation of the microalga Parietochloris incisa. Biochim Biophys Acta (2005) 1.04
Three-dimensional plasmonic chiral tetramers assembled by DNA origami. Nano Lett (2013) 1.04
Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway. J Biol Chem (2013) 1.04
Replacement of fish oil with thraustochytrid Schizochytrium sp. L oil in Atlantic salmon parr (Salmo salar L) diets. Comp Biochem Physiol A Mol Integr Physiol (2007) 1.03
A folate receptor-targeted liposomal formulation for paclitaxel. Int J Pharm (2006) 1.03
MASPIT: three-hybrid trap for quantitative proteome fingerprinting of small molecule-protein interactions in mammalian cells. Chem Biol (2006) 1.03
A novel action of histone deacetylase inhibitors in a protein aggresome disease model. Curr Biol (2004) 1.03
Differential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiation. Invest Ophthalmol Vis Sci (2004) 1.02
Transgenic production of arachidonic acid in oilseeds. Transgenic Res (2011) 1.02