Published in Kidney Int on December 23, 2009
Evaluation of the Heparin Binding Protein Levels in Sepsis (HBP) | NCT02533011
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care (2013) 3.90
Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease. JAMA (2015) 2.53
Acute kidney injury: what's the prognosis? Nat Rev Nephrol (2011) 2.51
Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int (2011) 2.22
A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury. Shock (2014) 2.11
Effects of fluid resuscitation with 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis*. Crit Care Med (2014) 1.66
Long-term clinical consequences of acute kidney injury in the HIV-infected. Kidney Int (2010) 1.65
Comparison of absolute serum creatinine changes versus Kidney Disease: Improving Global Outcomes consensus definitions for characterizing stages of acute kidney injury. Nephrol Dial Transplant (2013) 1.61
Cell-cycle arrest and acute kidney injury: the light and the dark sides. Nephrol Dial Transplant (2015) 1.59
Association between AKI and long-term renal and cardiovascular outcomes in United States veterans. Clin J Am Soc Nephrol (2013) 1.41
Renal angina: an emerging paradigm to identify children at risk for acute kidney injury. Pediatr Nephrol (2011) 1.35
Hospital-based acute care use in survivors of septic shock. Crit Care Med (2015) 1.34
Bactericidal antibiotics temporarily increase inflammation and worsen acute kidney injury in experimental sepsis. Crit Care Med (2012) 1.33
Derivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers. Nephrol Dial Transplant (2014) 1.26
Searching for mechanisms that matter in early septic acute kidney injury: an experimental study. Crit Care (2011) 1.19
Understanding urine output in critically ill patients. Ann Intensive Care (2011) 1.18
Renal replacement therapy in acute kidney injury: controversy and consensus. Crit Care (2015) 1.12
Toward an integrated research agenda for critical illness in aging. Am J Respir Crit Care Med (2010) 1.10
Invasive mechanical ventilation as a risk factor for acute kidney injury in the critically ill: a systematic review and meta-analysis. Crit Care (2013) 1.08
A multicentre study of acute kidney injury in severe sepsis and septic shock: association with inflammatory phenotype and HLA genotype. PLoS One (2012) 1.03
Plasma inflammatory and apoptosis markers are associated with dialysis dependence and death among critically ill patients receiving renal replacement therapy. Nephrol Dial Transplant (2014) 1.01
Sepsis-induced acute kidney injury revisited: pathophysiology, prevention and future therapies. Curr Opin Crit Care (2014) 1.00
AKI in low-risk versus high-risk patients in intensive care. Clin J Am Soc Nephrol (2014) 0.99
Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis. Crit Care Med (2016) 0.96
Differential effects of kidney-lung cross-talk during acute kidney injury and bacterial pneumonia. Kidney Int (2011) 0.91
Renal ischemia-reperfusion injury amplifies the humoral immune response. J Am Soc Nephrol (2013) 0.91
One dose of cyclosporine A is protective at initiation of folic acid-induced acute kidney injury in mice. Nephrol Dial Transplant (2012) 0.91
Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy. Crit Care (2014) 0.90
Personalizing blood pressure management in septic shock. Ann Intensive Care (2015) 0.86
Impairment of renal function using hyperoncotic colloids in a two hit model of shock: a prospective randomized study. Crit Care (2012) 0.86
Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department. Crit Care Med (2015) 0.86
Acute kidney injury in sepsis: questions answered, but others remain. Kidney Int (2010) 0.85
Cardiorenal syndromes and sepsis. Int J Nephrol (2011) 0.82
Erythrocyte superoxide dismutase as a biomarker of septic acute kidney injury. Ann Intensive Care (2016) 0.82
TIMP2•IGFBP7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients. J Trauma Acute Care Surg (2016) 0.81
Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice. PLoS One (2014) 0.81
Detrimental cross-talk between sepsis and acute kidney injury: new pathogenic mechanisms, early biomarkers and targeted therapies. Crit Care (2016) 0.81
Epithelial transport during septic acute kidney injury. Nephrol Dial Transplant (2013) 0.80
Risk Factors for Long-Term Mortality after Hospitalization for Community-Acquired Pneumonia: A 5-Year Prospective Follow-Up Study. PLoS One (2016) 0.80
Intermediate and long-term risk of new-onset heart failure after hospitalization for pneumonia in elderly adults. Am Heart J (2015) 0.79
Association of statin use with risk and outcome of acute kidney injury in community-acquired pneumonia. Clin J Am Soc Nephrol (2012) 0.78
IL-6 and TNF-α serum levels are associated with early death in community-acquired pneumonia patients. Braz J Med Biol Res (2015) 0.78
Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand. PLoS One (2015) 0.78
Diagnosis of acute kidney injury and its association with in-hospital mortality in patients with infective exacerbations of bronchiectasis: cohort study from a UK nationwide database. BMC Pulm Med (2016) 0.78
Approaches to the Management of Acute Kidney Injury in Children. Recent Pat Biomark (2011) 0.78
Effects of non-severe acute kidney injury on clinical outcomes in critically ill patients. Crit Care (2016) 0.78
Prehospitalization Risk Factors for Acute Kidney Injury during Hospitalization for Serious Infections in the REGARDS Cohort. Nephron Extra (2015) 0.77
Alpha-Lipoic Acid Attenuates Oxidative Damage in Organs After Sepsis. Inflammation (2016) 0.77
Clinical approach to the patient with AKI and sepsis. Semin Nephrol (2015) 0.77
Acute Kidney Injury in ADPKD Patients with Pneumonia. Int J Nephrol (2011) 0.76
Risk factors for developing acute kidney injury in older people with diabetes and community-acquired pneumonia: a population-based UK cohort study. BMC Nephrol (2017) 0.75
Osthole protects sepsis-induced acute kidney injury via down-regulating NF-κB signal pathway. Oncotarget (2016) 0.75
Sepsis and Acute Kidney Injury. Turk J Anaesthesiol Reanim (2014) 0.75
Effect of acute kidney injury requiring extended dialysis on 28 day and 1 year survival of patients undergoing interventional lung assist membrane ventilator treatment. BMC Nephrol (2011) 0.75
Hospitalization for Pneumonia is Associated With Decreased 1-Year Survival in Patients With Type 2 Diabetes: Results From a Prospective Cohort Study. Medicine (Baltimore) (2016) 0.75
Is Pneumonia a Risk Factor or a Risk Marker for Long-Term Mortality? Am J Respir Crit Care Med (2015) 0.75
Differentially expressed miRNAs in sepsis-induced acute kidney injury target oxidative stress and mitochondrial dysfunction pathways. PLoS One (2017) 0.75
Vitamin D Status and Long-Term Mortality in Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort. PLoS One (2016) 0.75
Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death. Crit Care (2016) 0.75
Predictive factors for renal failure and a control and treatment algorithm. Rev Lat Am Enfermagem (2015) 0.75
Practical approach to detection and management of acute kidney injury in critically ill patient. J Intensive Care (2017) 0.75
Effect of continuous renal replacement therapy on kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin in patients with septic acute kidney injury. Exp Ther Med (2017) 0.75
A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis (1987) 174.79
K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis (2002) 81.62
Random-effects models for longitudinal data. Biometrics (1982) 54.17
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med (2001) 46.58
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med (1996) 35.00
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med (2003) 28.68
Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med (2001) 27.70
A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med (1997) 24.87
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature (2002) 19.77
Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA (2005) 19.57
The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest (1991) 16.06
Points of control in inflammation. Nature (2002) 10.61
Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax (2003) 9.54
RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care (2006) 9.29
Acute renal failure and sepsis. N Engl J Med (2004) 7.18
Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial. JAMA (2001) 5.86
Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med (2007) 5.65
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA (2003) 4.54
Early acute kidney injury and sepsis: a multicentre evaluation. Crit Care (2008) 3.32
Long-term risk of mortality and acute kidney injury during hospitalization after major surgery. Ann Surg (2009) 3.18
Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes. Clin J Am Soc Nephrol (2007) 3.17
Effect of increasing the intensity of implementing pneumonia guidelines: a randomized, controlled trial. Ann Intern Med (2005) 3.13
Long-term risk of mortality and end-stage renal disease among the elderly after small increases in serum creatinine level during hospitalization for acute myocardial infarction. Arch Intern Med (2008) 2.99
A comparison of observed versus estimated baseline creatinine for determination of RIFLE class in patients with acute kidney injury. Nephrol Dial Transplant (2009) 2.55
Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int (2004) 2.52
Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J Immunol (2002) 1.96
Clinical practice. Management of community-acquired pneumonia. N Engl J Med (2002) 1.92
Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia. Am J Med (2005) 1.76
Comparison of Cox and Gray's survival models in severe sepsis. Crit Care Med (2004) 1.72
The prognostic importance of a small acute decrement in kidney function in hospitalized patients: a systematic review and meta-analysis. Am J Kidney Dis (2007) 1.66
Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis. Clin J Am Soc Nephrol (2006) 1.59
Clinical characteristics of patients developing ARF due to sepsis/systemic inflammatory response syndrome: results of a prospective study. Am J Kidney Dis (2004) 1.58
A tobit variance-component method for linkage analysis of censored trait data. Am J Hum Genet (2003) 1.49
Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase. Kidney Int (2001) 1.41
Acute kidney injury in patients with sepsis: a contemporary analysis. Int J Infect Dis (2008) 1.31
Rifle classification for predicting in-hospital mortality in critically ill sepsis patients. Shock (2009) 1.21
Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock. Am J Kidney Dis (2003) 1.12
Monoclonal antibody to tumor necrosis factor--alpha prevents lethal endotoxin sepsis in adult rhesus monkeys. J Lab Clin Med (1992) 1.00
Hemostatic disturbances in patients with systemic inflammatory response syndrome (SIRS) and associated acute renal failure (ARF). Thromb Res (2000) 0.88
Sepsis-related acute kidney injury: a protective effect of drotrecogin alpha (activated) treatment? Acta Anaesthesiol Scand (2008) 0.86
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care (2007) 29.89
Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA (2005) 19.57
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
A randomized trial of protocol-based care for early septic shock. N Engl J Med (2014) 16.05
Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med (2008) 14.40
Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. JAMA (2002) 9.89
RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care (2006) 9.29
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med (2010) 6.69
National estimates of severe sepsis in United States emergency departments. Crit Care Med (2007) 5.99
Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med (2007) 5.65
Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med (2012) 5.22
Variation in critical care services across North America and Western Europe. Crit Care Med (2008) 5.00
Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury. Crit Care Med (2004) 4.93
Acute kidney injury. Lancet (2012) 4.90
The epidemiology of severe sepsis in children in the United States. Am J Respir Crit Care Med (2002) 4.72
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med (2010) 4.64
The effect of multidisciplinary care teams on intensive care unit mortality. Arch Intern Med (2010) 4.41
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care (2013) 3.90
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA (2013) 3.78
Effects of hypercapnia on BP in hypoalbuminemic and Nagase analbuminemic rats. Chest (2007) 3.51
A comparison of three methods to estimate baseline creatinine for RIFLE classification. Nephrol Dial Transplant (2010) 3.45
Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia. Ann Emerg Med (2008) 3.44
Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Crit Care (2013) 3.40
Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome. Am J Respir Crit Care Med (2012) 3.36
Major complications, mortality, and resource utilization after open abdominal surgery: 0.9% saline compared to Plasma-Lyte. Ann Surg (2012) 3.36
The epidemiology of mechanical ventilation use in the United States. Crit Care Med (2010) 3.28
Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis. Crit Care Med (2007) 3.27
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med (2003) 3.18
Racial variation in the incidence, care, and outcomes of severe sepsis: analysis of population, patient, and hospital characteristics. Am J Respir Crit Care Med (2007) 3.17
The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*. Crit Care Med (2014) 3.17
Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes. Clin J Am Soc Nephrol (2007) 3.17
Intensive care unit quality improvement: a "how-to" guide for the interdisciplinary team. Crit Care Med (2006) 3.15
Pneumonia: still the old man's friend? Arch Intern Med (2003) 3.12
Diuretics and mortality in acute renal failure. Crit Care Med (2004) 3.12
Renal failure in the ICU: comparison of the impact of acute renal failure and end-stage renal disease on ICU outcomes. Kidney Int (2002) 3.07
Continuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (B.E.S.T. kidney) investigators. Intensive Care Med (2007) 3.03
Hospitalized community-acquired pneumonia in the elderly: age- and sex-related patterns of care and outcome in the United States. Am J Respir Crit Care Med (2002) 3.02
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med (2015) 2.97
Prospective meta-analysis using individual patient data in intensive care medicine. Intensive Care Med (2009) 2.93
Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication. Am J Respir Crit Care Med (2014) 2.93
Organizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study. Intensive Care Med (2015) 2.92
Three-year outcomes for Medicare beneficiaries who survive intensive care. JAMA (2010) 2.87
The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection. Ann Emerg Med (2006) 2.84
The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. Am J Respir Crit Care Med (2012) 2.72
Defining acute renal failure: physiological principles. Intensive Care Med (2003) 2.69
External validation of severity scoring systems for acute renal failure using a multinational database. Crit Care Med (2005) 2.68
Trends in the epidemiology of pediatric severe sepsis*. Pediatr Crit Care Med (2013) 2.67
Critical care medicine training and certification for emergency physicians. Ann Emerg Med (2005) 2.67
Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis. Gut (2011) 2.65
Acute kidney injury: an increasing global concern. Lancet (2013) 2.61
End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med (2006) 2.61
Discontinuation of continuous renal replacement therapy: a post hoc analysis of a prospective multicenter observational study. Crit Care Med (2009) 2.58
A comparison of observed versus estimated baseline creatinine for determination of RIFLE class in patients with acute kidney injury. Nephrol Dial Transplant (2009) 2.55
Acute kidney injury: what's the prognosis? Nat Rev Nephrol (2011) 2.51
Disability among elderly survivors of mechanical ventilation. Am J Respir Crit Care Med (2010) 2.50
Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med (2003) 2.44
Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe. Intensive Care Med (2013) 2.44
Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference. Crit Care Med (2007) 2.42
Relationship between staff perceptions of hospital norms and hospital-level end-of-life treatment intensity. J Palliat Med (2007) 2.39
Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med (2003) 2.39
Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit Care Med (2008) 2.37
Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury. J Crit Care (2008) 2.36
Is survival better at hospitals with higher "end-of-life" treatment intensity? Med Care (2010) 2.35
A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis. Crit Care Med (2010) 2.31
Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS database. Liver Transpl (2004) 2.31
Growth of intensive care unit resource use and its estimated cost in Medicare. Crit Care Med (2008) 2.31
Severe sepsis epidemiology: sampling, selection, and society. Crit Care (2004) 2.28
Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis. JAMA (2010) 2.27
Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis. Nephrol Dial Transplant (2009) 2.27
Perceptions of safety culture vary across the intensive care units of a single institution. Crit Care Med (2007) 2.24
Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA (2014) 2.23
Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int (2011) 2.22
Plasma microRNAs as novel biomarkers for endometriosis and endometriosis-associated ovarian cancer. Clin Cancer Res (2013) 2.15
Posttraumatic stress and complicated grief in family members of patients in the intensive care unit. J Gen Intern Med (2008) 2.12
Critical care medicine training and certification for emergency physicians. Crit Care Med (2005) 2.12
A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury. Shock (2014) 2.11
Haloperidol use is associated with lower hospital mortality in mechanically ventilated patients. Crit Care Med (2005) 2.11
Severe sepsis and septic shock. N Engl J Med (2013) 2.10
A comparison of critical care research funding and the financial burden of critical illness in the United States. Crit Care Med (2012) 2.07
Do hospitals provide lower quality of care to black patients for pneumonia? Crit Care Med (2010) 2.07