| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study.
|
Blood
|
2010
|
4.17
|
|
2
|
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome.
|
Lancet
|
2008
|
3.69
|
|
3
|
Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95.
|
Blood
|
2008
|
2.68
|
|
4
|
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias.
|
J Exp Med
|
2011
|
2.59
|
|
5
|
Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk.
|
Nat Genet
|
2010
|
2.47
|
|
6
|
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group.
|
Blood
|
2009
|
2.44
|
|
7
|
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray.
|
Blood
|
2007
|
2.31
|
|
8
|
Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.
|
Blood
|
2006
|
2.10
|
|
9
|
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.
|
J Clin Invest
|
2010
|
1.97
|
|
10
|
IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.
|
Blood
|
2013
|
1.91
|
|
11
|
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol.
|
Blood
|
2010
|
1.86
|
|
12
|
NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway.
|
Nat Med
|
2009
|
1.66
|
|
13
|
Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.
|
Blood
|
2009
|
1.64
|
|
14
|
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia.
|
Nat Med
|
2006
|
1.52
|
|
15
|
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.
|
Haematologica
|
2012
|
1.50
|
|
16
|
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype.
|
Blood
|
2013
|
1.45
|
|
17
|
Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia.
|
Blood
|
2004
|
1.39
|
|
18
|
Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia.
|
Blood
|
2003
|
1.36
|
|
19
|
Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.
|
Proc Natl Acad Sci U S A
|
2008
|
1.34
|
|
20
|
Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations.
|
EMBO Mol Med
|
2012
|
1.22
|
|
21
|
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
|
Blood
|
2012
|
1.22
|
|
22
|
Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.
|
Blood
|
2011
|
1.21
|
|
23
|
Prediction of outcome by early bone marrow response in childhood acute lymphoblastic leukemia treated in the ALL-BFM 95 trial: differential effects in precursor B-cell and T-cell leukemia.
|
Haematologica
|
2012
|
1.17
|
|
24
|
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.
|
BMC Med Genet
|
2005
|
1.15
|
|
25
|
High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response.
|
Blood
|
2009
|
1.13
|
|
26
|
Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group.
|
Br J Haematol
|
2010
|
1.10
|
|
27
|
Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia.
|
Haematologica
|
2011
|
1.07
|
|
28
|
Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia.
|
J Exp Med
|
2013
|
1.07
|
|
29
|
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
|
Genes Chromosomes Cancer
|
2003
|
1.06
|
|
30
|
NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia.
|
Haematologica
|
2013
|
1.06
|
|
31
|
Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia.
|
Blood
|
2013
|
1.04
|
|
32
|
Second malignant neoplasms after treatment of childhood acute lymphoblastic leukemia.
|
J Clin Oncol
|
2013
|
0.96
|
|
33
|
Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.
|
Pediatr Blood Cancer
|
2012
|
0.95
|
|
34
|
Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups.
|
Br J Haematol
|
2012
|
0.95
|
|
35
|
Gene expression profile of the infective murine model for biliary atresia.
|
Pediatr Surg Int
|
2006
|
0.94
|
|
36
|
High interleukin-15 expression characterizes childhood acute lymphoblastic leukemia with involvement of the CNS.
|
J Clin Oncol
|
2007
|
0.94
|
|
37
|
Leukemia surfaceome analysis reveals new disease-associated features.
|
Blood
|
2013
|
0.93
|
|
38
|
Tumor necrosis factor and lymphotoxin alfa genetic polymorphisms and outcome in pediatric patients with non-Hodgkin's lymphoma: results from Berlin-Frankfurt-Münster Trial NHL-BFM 95.
|
J Clin Oncol
|
2005
|
0.93
|
|
39
|
Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.
|
Blood
|
2014
|
0.93
|
|
40
|
MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95.
|
Ann Hematol
|
2006
|
0.92
|
|
41
|
Small sizes and indolent evolutionary dynamics challenge the potential role of P2RY8-CRLF2-harboring clones as main relapse-driving force in childhood ALL.
|
Blood
|
2012
|
0.91
|
|
42
|
A cross-sectional study of self-reported chemical-related sensitivity is associated with gene variants of drug-metabolizing enzymes.
|
Environ Health
|
2007
|
0.91
|
|
43
|
Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome.
|
Haematologica
|
2011
|
0.90
|
|
44
|
Gene expression profiles and risk stratification in childhood acute lymphoblastic leukemia.
|
Haematologica
|
2004
|
0.89
|
|
45
|
Bridging the gap between the north and south of the world: the case of treatment response in childhood acute lymphoblastic leukemia.
|
Haematologica
|
2009
|
0.87
|
|
46
|
The NQO1 C609T polymorphism is associated with risk of secondary malignant neoplasms after treatment for childhood acute lymphoblastic leukemia: a matched-pair analysis from the ALL-BFM study group.
|
Haematologica
|
2007
|
0.86
|
|
47
|
NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms.
|
Haematologica
|
2004
|
0.84
|
|
48
|
Thymidylate synthase gene polymorphism and its association with relapse in childhood B-cell precursor acute lymphoblastic leukemia.
|
Haematologica
|
2003
|
0.83
|
|
49
|
Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease.
|
Genes Chromosomes Cancer
|
2008
|
0.83
|
|
50
|
Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia.
|
Ann Hematol
|
2008
|
0.82
|
|
51
|
Anemia and survival in childhood acute lymphoblastic leukemia.
|
Haematologica
|
2008
|
0.82
|
|
52
|
Polymorphisms within glutathione S-transferase genes in pediatric non-Hodgkin's lymphoma.
|
Haematologica
|
2002
|
0.81
|
|
53
|
Methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and risk of pediatric non-Hodgkin lymphoma in a German study population.
|
Blood
|
2005
|
0.80
|
|
54
|
Childhood cancer incidence patterns by race, sex and age for 2000-2006: a report from the South African National Cancer Registry.
|
Int J Cancer
|
2014
|
0.79
|
|
55
|
Misconceptions, challenges, uncertainty, and progress in guideline recommendations.
|
Semin Hematol
|
2008
|
0.79
|
|
56
|
The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7-9, 2011.
|
Pediatr Blood Cancer
|
2012
|
0.79
|
|
57
|
Quantification of free total plasma DNA and minimal residual disease detection in the plasma of children with acute lymphoblastic leukemia.
|
Ann Hematol
|
2009
|
0.79
|
|
58
|
Childhood acute lymphoblastic leukemia-associated risk-loci IKZF1, ARID5B and CEBPE and risk of pediatric non-Hodgkin lymphoma: a report from the Berlin-Frankfurt-Münster Study Group.
|
Leuk Lymphoma
|
2014
|
0.79
|
|
59
|
Heterogeneous expression pattern of pro- and anti-apoptotic factors in myeloid progenitor cells of patients with severe congenital neutropenia treated with granulocyte colony-stimulating factor.
|
Br J Haematol
|
2005
|
0.78
|
|
60
|
Genetic polymorphisms of the lymphotoxin alpha gene are associated with increased risk for lethal infections during induction therapy for childhood acute leukemia: a case-control study.
|
Int J Hematol
|
2009
|
0.78
|
|
61
|
CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.
|
Blood
|
2010
|
0.78
|
|
62
|
Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia.
|
Hum Mol Genet
|
2013
|
0.76
|
|
63
|
Emergence of translocation t(9;11)-positive leukemia during treatment of childhood acute lymphoblastic leukemia.
|
Genes Chromosomes Cancer
|
2004
|
0.75
|
|
64
|
High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.
|
Haematologica
|
2013
|
0.75
|
|
65
|
Corrigendum: S100-alarmin-induced innate immune programming protects newborn infants from sepsis.
|
Nat Immunol
|
2017
|
0.75
|
|
66
|
Multiplex ligation-dependent probe amplification validates LOH6q analyses and enhances insight into chromosome 6q aberrations in pediatric T-cell lymphoblastic leukemia and lymphoma.
|
Leuk Lymphoma
|
2014
|
0.75
|