Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
|
Science
|
2007
|
51.70
|
2
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
3
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
4
|
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
|
Nat Genet
|
2008
|
22.35
|
5
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
6
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
7
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
8
|
Variants in MTNR1B influence fasting glucose levels.
|
Nat Genet
|
2008
|
10.85
|
9
|
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
|
Nat Genet
|
2008
|
9.39
|
10
|
Clinical risk factors, DNA variants, and the development of type 2 diabetes.
|
N Engl J Med
|
2008
|
8.70
|
11
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
12
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
13
|
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
|
PLoS Genet
|
2009
|
5.81
|
14
|
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
|
J Clin Invest
|
2007
|
5.02
|
15
|
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.
|
Nat Genet
|
2008
|
4.84
|
16
|
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.
|
Diabetes
|
2006
|
4.36
|
17
|
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.
|
Diabetes
|
2008
|
4.20
|
18
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
19
|
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.
|
Diabetes
|
2007
|
3.84
|
20
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
21
|
Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes.
|
Diabetes
|
2005
|
2.99
|
22
|
Genetic prediction of future type 2 diabetes.
|
PLoS Med
|
2005
|
2.98
|
23
|
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.
|
Diabetes
|
2004
|
2.52
|
24
|
Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes.
|
Diabetes
|
2008
|
2.51
|
25
|
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
|
Diabetes
|
2010
|
2.44
|
26
|
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.
|
PLoS Genet
|
2007
|
2.35
|
27
|
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|
Diabetes
|
2011
|
2.21
|
28
|
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.
|
Nat Genet
|
2013
|
1.91
|
29
|
Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study.
|
Diabetes Care
|
2008
|
1.81
|
30
|
Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants.
|
Genet Epidemiol
|
2011
|
1.78
|
31
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
32
|
Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I.
|
J Clin Endocrinol Metab
|
2004
|
1.68
|
33
|
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance.
|
Diabetes
|
2012
|
1.63
|
34
|
Contribution of insulin-stimulated glucose uptake and basal hepatic insulin sensitivity to surrogate measures of insulin sensitivity.
|
Diabetes Care
|
2004
|
1.60
|
35
|
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
|
Diabetes
|
2009
|
1.42
|
36
|
Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes.
|
Diabetes
|
2008
|
1.35
|
37
|
Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes.
|
Diabetes
|
2004
|
1.32
|
38
|
Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity.
|
Diabetes
|
2006
|
1.26
|
39
|
Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes.
|
Diabetes
|
2005
|
1.22
|
40
|
Importance of obtaining independent measures of insulin secretion and insulin sensitivity during the same test: results with the Botnia clamp.
|
Diabetes Care
|
2003
|
1.21
|
41
|
Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.
|
Diabetes
|
2007
|
1.20
|
42
|
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
|
Diabetes
|
2003
|
1.17
|
43
|
The SLC6A14 gene shows evidence of association with obesity.
|
J Clin Invest
|
2003
|
1.15
|
44
|
GAD antibody positivity predicts type 2 diabetes in an adult population.
|
Diabetes
|
2009
|
1.12
|
45
|
Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people.
|
Diabetes
|
2005
|
1.12
|
46
|
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
|
Hum Mol Genet
|
2003
|
1.11
|
47
|
Minimal contribution of fasting hyperglycemia to the incidence of type 2 diabetes in subjects with normal 2-h plasma glucose.
|
Diabetes Care
|
2009
|
1.11
|
48
|
Pleiotropic effects of GIP on islet function involve osteopontin.
|
Diabetes
|
2011
|
1.08
|
49
|
Stressful life events and the metabolic syndrome: the prevalence, prediction and prevention of diabetes (PPP)-Botnia Study.
|
Diabetes Care
|
2009
|
1.07
|
50
|
The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes.
|
Diabetes Metab Res Rev
|
2010
|
1.05
|
51
|
Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans.
|
Diabetes
|
2013
|
1.02
|
52
|
Complex relationship between blood pressure and mortality in type 2 diabetic patients: a follow-up of the Botnia Study.
|
Hypertension
|
2005
|
0.97
|
53
|
Clinical heterogeneity in monogenic diabetes caused by mutations in the glucokinase gene (GCK-MODY).
|
Diabetes Care
|
2009
|
0.96
|
54
|
Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts.
|
Diabetologia
|
2014
|
0.93
|
55
|
Link between GIP and osteopontin in adipose tissue and insulin resistance.
|
Diabetes
|
2013
|
0.92
|
56
|
Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study.
|
Ann Med
|
2011
|
0.91
|
57
|
High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people.
|
Diabetes
|
2006
|
0.91
|
58
|
Sleep duration and insulin resistance in individuals without type 2 diabetes: the PPP-Botnia study.
|
Ann Med
|
2014
|
0.90
|
59
|
Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time.
|
Eur J Hum Genet
|
2011
|
0.89
|
60
|
A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes.
|
J Clin Endocrinol Metab
|
2003
|
0.88
|
61
|
Metabolite profiling reveals normal metabolic control in carriers of mutations in the glucokinase gene (MODY2).
|
Diabetes
|
2012
|
0.87
|
62
|
Cosegregation of MIDD and MODY in a pedigree: functional and clinical consequences.
|
Diabetes
|
2004
|
0.87
|
63
|
Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people.
|
Diabetes
|
2005
|
0.85
|
64
|
The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.
|
Diabetes
|
2006
|
0.85
|
65
|
Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes.
|
Diabetes
|
2006
|
0.85
|
66
|
Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years.
|
Diabetes Care
|
2010
|
0.85
|
67
|
Two-step approach for the prediction of future type 2 diabetes risk.
|
Diabetes Care
|
2011
|
0.84
|
68
|
Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study.
|
Diabetes Care
|
2011
|
0.84
|
69
|
Oral glucose tolerance test should be performed after stroke and transient ischemic attack.
|
Int J Stroke
|
2011
|
0.84
|
70
|
Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.
|
PLoS One
|
2009
|
0.83
|
71
|
Contribution of known and unknown susceptibility genes to early-onset diabetes in scandinavia: evidence for heterogeneity.
|
Diabetes
|
2002
|
0.83
|
72
|
Subjective sleep complaints are associated with insulin resistance in individuals without diabetes: the PPP-Botnia Study.
|
Diabetes Care
|
2012
|
0.81
|
73
|
Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes.
|
Diabetologia
|
2014
|
0.81
|
74
|
Zinc transporter type 8 autoantibodies (ZnT8A): prevalence and phenotypic associations in latent autoimmune diabetes patients and patients with adult onset type 1 diabetes.
|
Autoimmunity
|
2013
|
0.80
|
75
|
Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study.
|
Eur J Endocrinol
|
2012
|
0.78
|
76
|
[Long-acting insulin analog, glargine, in the treatment of type 1 diabetes].
|
Duodecim
|
2004
|
0.75
|
77
|
[MODY diabetes--a monogenic developmental and functional disturbance of pancreatic beta cells].
|
Duodecim
|
2012
|
0.75
|
78
|
Adolescents at risk for MODY3 diabetes prefer genetic testing before adulthood.
|
Diabetes Care
|
2007
|
0.75
|
79
|
[Diabetic with hallucination].
|
Duodecim
|
2005
|
0.75
|
80
|
[Not Available].
|
Duodecim
|
2007
|
0.75
|
81
|
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
|
Circ Cardiovasc Genet
|
2017
|
0.75
|
82
|
[Update on Current Care Guideline. Diabetes].
|
Duodecim
|
2016
|
0.75
|
83
|
[Cystic kidney disease and diabetes--an underdiagnosed monogenic developmental disorder].
|
Duodecim
|
2012
|
0.75
|
84
|
[Persistent asthma and hypokalemia].
|
Duodecim
|
2005
|
0.75
|
85
|
A Bayesian Network analysis of the probabilistic relations between risk factors in the predisposition to type 2 diabetes.
|
Conf Proc IEEE Eng Med Biol Soc
|
2015
|
0.75
|