Tiinamaija Tuomi

Author PubWeight™ 317.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007 51.70
2 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
3 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
4 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
5 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
6 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
7 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
8 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
9 Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008 9.39
10 Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 2008 8.70
11 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
12 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
13 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
14 Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest 2007 5.02
15 Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet 2008 4.84
16 Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes 2006 4.36
17 Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 2008 4.20
18 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
19 Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes 2007 3.84
20 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
21 Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes. Diabetes 2005 2.99
22 Genetic prediction of future type 2 diabetes. PLoS Med 2005 2.98
23 Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes 2004 2.52
24 Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes. Diabetes 2008 2.51
25 Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes 2010 2.44
26 The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet 2007 2.35
27 Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes 2011 2.21
28 Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. Nat Genet 2013 1.91
29 Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study. Diabetes Care 2008 1.81
30 Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants. Genet Epidemiol 2011 1.78
31 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
32 Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I. J Clin Endocrinol Metab 2004 1.68
33 Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance. Diabetes 2012 1.63
34 Contribution of insulin-stimulated glucose uptake and basal hepatic insulin sensitivity to surrogate measures of insulin sensitivity. Diabetes Care 2004 1.60
35 A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes 2009 1.42
36 Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes. Diabetes 2008 1.35
37 Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes. Diabetes 2004 1.32
38 Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity. Diabetes 2006 1.26
39 Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes. Diabetes 2005 1.22
40 Importance of obtaining independent measures of insulin secretion and insulin sensitivity during the same test: results with the Botnia clamp. Diabetes Care 2003 1.21
41 Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men. Diabetes 2007 1.20
42 A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity. Diabetes 2003 1.17
43 The SLC6A14 gene shows evidence of association with obesity. J Clin Invest 2003 1.15
44 GAD antibody positivity predicts type 2 diabetes in an adult population. Diabetes 2009 1.12
45 Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people. Diabetes 2005 1.12
46 A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes. Hum Mol Genet 2003 1.11
47 Minimal contribution of fasting hyperglycemia to the incidence of type 2 diabetes in subjects with normal 2-h plasma glucose. Diabetes Care 2009 1.11
48 Pleiotropic effects of GIP on islet function involve osteopontin. Diabetes 2011 1.08
49 Stressful life events and the metabolic syndrome: the prevalence, prediction and prevention of diabetes (PPP)-Botnia Study. Diabetes Care 2009 1.07
50 The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes. Diabetes Metab Res Rev 2010 1.05
51 Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans. Diabetes 2013 1.02
52 Complex relationship between blood pressure and mortality in type 2 diabetic patients: a follow-up of the Botnia Study. Hypertension 2005 0.97
53 Clinical heterogeneity in monogenic diabetes caused by mutations in the glucokinase gene (GCK-MODY). Diabetes Care 2009 0.96
54 Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts. Diabetologia 2014 0.93
55 Link between GIP and osteopontin in adipose tissue and insulin resistance. Diabetes 2013 0.92
56 Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study. Ann Med 2011 0.91
57 High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people. Diabetes 2006 0.91
58 Sleep duration and insulin resistance in individuals without type 2 diabetes: the PPP-Botnia study. Ann Med 2014 0.90
59 Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time. Eur J Hum Genet 2011 0.89
60 A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes. J Clin Endocrinol Metab 2003 0.88
61 Metabolite profiling reveals normal metabolic control in carriers of mutations in the glucokinase gene (MODY2). Diabetes 2012 0.87
62 Cosegregation of MIDD and MODY in a pedigree: functional and clinical consequences. Diabetes 2004 0.87
63 Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people. Diabetes 2005 0.85
64 The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people. Diabetes 2006 0.85
65 Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes. Diabetes 2006 0.85
66 Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years. Diabetes Care 2010 0.85
67 Two-step approach for the prediction of future type 2 diabetes risk. Diabetes Care 2011 0.84
68 Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study. Diabetes Care 2011 0.84
69 Oral glucose tolerance test should be performed after stroke and transient ischemic attack. Int J Stroke 2011 0.84
70 Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins. PLoS One 2009 0.83
71 Contribution of known and unknown susceptibility genes to early-onset diabetes in scandinavia: evidence for heterogeneity. Diabetes 2002 0.83
72 Subjective sleep complaints are associated with insulin resistance in individuals without diabetes: the PPP-Botnia Study. Diabetes Care 2012 0.81
73 Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes. Diabetologia 2014 0.81
74 Zinc transporter type 8 autoantibodies (ZnT8A): prevalence and phenotypic associations in latent autoimmune diabetes patients and patients with adult onset type 1 diabetes. Autoimmunity 2013 0.80
75 Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study. Eur J Endocrinol 2012 0.78
76 [Long-acting insulin analog, glargine, in the treatment of type 1 diabetes]. Duodecim 2004 0.75
77 [MODY diabetes--a monogenic developmental and functional disturbance of pancreatic beta cells]. Duodecim 2012 0.75
78 Adolescents at risk for MODY3 diabetes prefer genetic testing before adulthood. Diabetes Care 2007 0.75
79 [Diabetic with hallucination]. Duodecim 2005 0.75
80 [Not Available]. Duodecim 2007 0.75
81 New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circ Cardiovasc Genet 2017 0.75
82 [Update on Current Care Guideline. Diabetes]. Duodecim 2016 0.75
83 [Cystic kidney disease and diabetes--an underdiagnosed monogenic developmental disorder]. Duodecim 2012 0.75
84 [Persistent asthma and hypokalemia]. Duodecim 2005 0.75
85 A Bayesian Network analysis of the probabilistic relations between risk factors in the predisposition to type 2 diabetes. Conf Proc IEEE Eng Med Biol Soc 2015 0.75