Robert Sladek

Author PubWeight™ 118.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
2 Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 2007 9.88
3 Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics. Proc Natl Acad Sci U S A 2003 6.87
4 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
5 A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2008 5.49
6 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009 5.43
7 A survey of genetic and epigenetic variation affecting human gene expression. Physiol Genomics 2004 4.99
8 Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies. Genome Res 2002 4.49
9 A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 2008 4.38
10 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
11 Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression. PLoS Genet 2008 3.92
12 Characterization of variability in large-scale gene expression data: implications for study design. Genomics 2002 3.42
13 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
14 Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes 2009 2.92
15 Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol Cell Biol 2003 2.65
16 Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. Nat Genet 2012 2.15
17 A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet 2009 2.09
18 Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome. PLoS One 2010 1.99
19 Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. PLoS One 2008 1.94
20 Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells. Oncogene 2002 1.82
21 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
22 The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am J Respir Cell Mol Biol 2003 1.62
23 Microarray analysis of uterine gene expression in mouse and human pregnancy. Mol Endocrinol 2003 1.41
24 Functional classes of bronchial mucosa genes that are differentially expressed in asthma. BMC Genomics 2004 1.32
25 Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation. Mol Endocrinol 2002 1.30
26 Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits. Diabetes 2009 1.29
27 The protein kinase PKR: a molecular clock that sequentially activates survival and death programs. EMBO J 2004 1.29
28 Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans. Hum Genet 2009 1.20
29 A methodology for global validation of microarray experiments. BMC Bioinformatics 2006 1.19
30 Comparison of the effects of Leishmania major or Leishmania donovani infection on macrophage gene expression. Infect Immun 2007 1.04
31 Mapping of clinical and expression quantitative trait loci in a sex-dependent effect of host susceptibility to mouse-adapted influenza H3N2/HK/1/68. J Immunol 2012 1.03
32 Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells. Endocrinology 2010 1.03
33 Mapping cis-acting regulatory variation in recombinant congenic strains. Physiol Genomics 2006 1.00
34 Denaturation mapping of Saccharomyces cerevisiae. Lab Chip 2012 0.96
35 Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death. Cancer Res 2006 0.91
36 An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria. PLoS One 2012 0.83
37 Application of expression microarrays to the investigation of fetal lung development in a glucocorticoid receptor knockout mouse model. Chest 2002 0.80
38 An electrochemically controlled microcantilever biosensor. Langmuir 2013 0.79
39 Development of a platform for single cell genomics using convex lens-induced confinement. Lab Chip 2015 0.77
40 Vav-1 expression correlates with NFκB activation and CD40-mediated cell death in diffuse large B-cell lymphoma cell lines. Hematol Oncol 2010 0.77
41 Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals. J Clin Endocrinol Metab 2014 0.75
42 Multilevel space-time aggregation for bright field cell microscopy segmentation and tracking. Int J Biomed Imaging 2010 0.75
43 Bioinformatics in research and clinical practice. Clin Invest Med 2003 0.75