| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
2
|
Variation in FTO contributes to childhood obesity and severe adult obesity.
|
Nat Genet
|
2007
|
13.62
|
|
3
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
|
4
|
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.
|
Nat Genet
|
2009
|
6.39
|
|
5
|
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.
|
Nat Genet
|
2008
|
5.49
|
|
6
|
Influence of experience on performance of individual surgeons in thyroid surgery: prospective cross sectional multicentre study.
|
BMJ
|
2012
|
5.25
|
|
7
|
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
|
Nat Genet
|
2005
|
4.44
|
|
8
|
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion.
|
J Cell Sci
|
2006
|
3.82
|
|
9
|
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.
|
Nature
|
2012
|
3.41
|
|
10
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
11
|
Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes.
|
Diabetes
|
2006
|
2.85
|
|
12
|
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.
|
Cell Metab
|
2012
|
2.22
|
|
13
|
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|
Diabetes
|
2011
|
2.21
|
|
14
|
Inflammation is associated with a decrease of lipogenic factors in omental fat in women.
|
Am J Physiol Regul Integr Comp Physiol
|
2008
|
1.88
|
|
15
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
16
|
Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease.
|
Gastroenterology
|
2009
|
1.67
|
|
17
|
Prevalence of loss-of-function FTO mutations in lean and obese individuals.
|
Diabetes
|
2009
|
1.54
|
|
18
|
An analysis of the biochemical diagnosis of 66 pheochromocytomas.
|
Eur J Endocrinol
|
2007
|
1.47
|
|
19
|
Impact of endotoxin challenge in obese pigs.
|
Shock
|
2014
|
1.43
|
|
20
|
Early prediction of failure to lose weight after obesity surgery.
|
Surg Obes Relat Dis
|
2011
|
1.40
|
|
21
|
PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.
|
Cell Metab
|
2009
|
1.21
|
|
22
|
Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration.
|
Int J Cancer
|
2012
|
1.14
|
|
23
|
Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity.
|
Diabetes
|
2011
|
1.12
|
|
24
|
The evolution of severe steatosis after bariatric surgery is related to insulin resistance.
|
Gastroenterology
|
2006
|
1.09
|
|
25
|
The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity.
|
FEBS Lett
|
2010
|
1.08
|
|
26
|
Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus.
|
J Biol Chem
|
2011
|
1.06
|
|
27
|
Glucotoxicity inhibits late steps of insulin exocytosis.
|
Endocrinology
|
2007
|
1.04
|
|
28
|
1,25-dihydroxyvitamin D3 protects RINm5F and human islet cells against cytokine-induced apoptosis: implication of the antiapoptotic protein A20.
|
Endocrinology
|
2002
|
1.03
|
|
29
|
Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets.
|
Diabetes
|
2009
|
1.02
|
|
30
|
Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.
|
PLoS One
|
2010
|
1.02
|
|
31
|
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
|
Diabetes
|
2006
|
1.02
|
|
32
|
PPARgamma-dependent and -independent effects of rosiglitazone on lipotoxic human pancreatic islets.
|
Biochem Biophys Res Commun
|
2007
|
1.01
|
|
33
|
Inflammatory role of Toll-like receptors in human and murine adipose tissue.
|
Mediators Inflamm
|
2010
|
1.01
|
|
34
|
Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone.
|
Am J Physiol Regul Integr Comp Physiol
|
2012
|
1.01
|
|
35
|
Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features.
|
J Clin Invest
|
2013
|
0.96
|
|
36
|
Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk.
|
J Clin Invest
|
2014
|
0.96
|
|
37
|
Intragastric balloon for preoperative weight reduction in candidates for laparoscopic gastric bypass with massive obesity.
|
Obes Surg
|
2006
|
0.95
|
|
38
|
Rapid purification of human ductal cells from human pancreatic fractions with surface antibody CA19-9.
|
Biochem Biophys Res Commun
|
2004
|
0.95
|
|
39
|
MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids.
|
J Clin Invest
|
2015
|
0.95
|
|
40
|
Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data.
|
PLoS One
|
2012
|
0.94
|
|
41
|
Human adipose tissue macrophages display activation of cancer-related pathways.
|
J Biol Chem
|
2012
|
0.93
|
|
42
|
Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.
|
Diabetes
|
2010
|
0.92
|
|
43
|
Roux-en-Y gastric bypass versus adjustable gastric banding to reduce nonalcoholic fatty liver disease: a 5-year controlled longitudinal study.
|
Ann Surg
|
2014
|
0.92
|
|
44
|
[Value of endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localization of insulinomas and gastrinomas. Experience of 54 cases].
|
Gastroenterol Clin Biol
|
2002
|
0.91
|
|
45
|
Cell-specific dysregulation of microRNA expression in obese white adipose tissue.
|
J Clin Endocrinol Metab
|
2014
|
0.91
|
|
46
|
Intraperitoneal insulin infusion versus islet transplantation: comparative study in patients with type 1 diabetes.
|
Transplantation
|
2009
|
0.91
|
|
47
|
Local-regional recurrence of sporadic or syndromic abdominal extra-adrenal paraganglioma: incidence, characteristics, and outcome.
|
Surgery
|
2009
|
0.91
|
|
48
|
Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock.
|
Crit Care
|
2014
|
0.91
|
|
49
|
The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells.
|
Mol Endocrinol
|
2012
|
0.90
|
|
50
|
Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
|
Eur J Gastroenterol Hepatol
|
2011
|
0.89
|
|
51
|
Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.
|
Diabetes
|
2011
|
0.89
|
|
52
|
Evidence for a membrane carbonic anhydrase IV anchored by its C-terminal peptide in normal human pancreatic ductal cells.
|
Histochem Cell Biol
|
2004
|
0.88
|
|
53
|
Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity.
|
PLoS One
|
2013
|
0.88
|
|
54
|
Preoperative weight loss with intragastric balloon decreases the risk of significant adverse outcomes of laparoscopic gastric bypass in super-super obese patients.
|
Obes Surg
|
2012
|
0.88
|
|
55
|
Alternative human liver transcripts of TCF7L2 bind to the gluconeogenesis regulator HNF4α at the protein level.
|
Diabetologia
|
2014
|
0.87
|
|
56
|
Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages.
|
FEBS J
|
2010
|
0.87
|
|
57
|
PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion.
|
Biochem Biophys Res Commun
|
2009
|
0.86
|
|
58
|
Implication of Reg I in human pancreatic duct-like cells in vivo in the pathological pancreas and in vitro during exocrine dedifferentiation.
|
Pancreas
|
2004
|
0.85
|
|
59
|
Should genetic testing be performed in each patient with sporadic pheochromocytoma at presentation?
|
Eur J Endocrinol
|
2008
|
0.85
|
|
60
|
In vivo and in vitro effect of sirolimus on insulin secretion.
|
Transplantation
|
2007
|
0.85
|
|
61
|
Gabapentin attenuates late but not early postoperative pain after thyroidectomy with superficial cervical plexus block.
|
Anesth Analg
|
2008
|
0.84
|
|
62
|
mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
|
J Endocrinol
|
2013
|
0.84
|
|
63
|
Development of a charting method to monitor the individual performance of surgeons at the beginning of their career.
|
PLoS One
|
2012
|
0.84
|
|
64
|
5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line.
|
Biochem Biophys Res Commun
|
2009
|
0.84
|
|
65
|
Efficient gene delivery and silencing of mouse and human pancreatic islets.
|
BMC Biotechnol
|
2010
|
0.83
|
|
66
|
Molecular screening for a personalized treatment approach in advanced adrenocortical cancer.
|
J Clin Endocrinol Metab
|
2013
|
0.83
|
|
67
|
PPARβ/δ activation induces enteroendocrine L cell GLP-1 production.
|
Gastroenterology
|
2011
|
0.83
|
|
68
|
Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates.
|
Cell Mol Life Sci
|
2013
|
0.83
|
|
69
|
Upgrading pretransplant human islet culture technology requires human serum combined with media renewal.
|
Transplantation
|
2010
|
0.82
|
|
70
|
Bariatric surgery for curing NASH in the morbidly obese?
|
J Hepatol
|
2013
|
0.82
|
|
71
|
EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families.
|
Diabetes
|
2006
|
0.82
|
|
72
|
Glucose regulates LXRalpha subcellular localization and function in rat pancreatic beta-cells.
|
Cell Res
|
2006
|
0.82
|
|
73
|
Poorly differentiated thyroid carcinomas: application of the Turin proposal provides prognostic results similar to those from the assessment of high-grade features.
|
Histopathology
|
2013
|
0.81
|
|
74
|
Expression of progenitor cell markers during expansion of sorted human pancreatic beta cells.
|
Gene Expr
|
2005
|
0.80
|
|
75
|
MUC1 expression in papillary thyroid carcinoma is associated with BRAF mutation and lymph node metastasis; the latter is the most important risk factor of relapse.
|
Thyroid
|
2014
|
0.80
|
|
76
|
Activation of intestinal peroxisome proliferator-activated receptor-α increases high-density lipoprotein production.
|
Eur Heart J
|
2012
|
0.80
|
|
77
|
Malignant insulinoma: recommendations for characterisation and treatment.
|
Ann Endocrinol (Paris)
|
2013
|
0.80
|
|
78
|
Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.
|
PLoS One
|
2013
|
0.80
|
|
79
|
Laparoscopic spleen-preserving distal pancreatectomy followed by intramuscular autologous islet transplantation for traumatic pancreatic transection in a young adult.
|
JOP
|
2012
|
0.79
|
|
80
|
International workshop: islet transplantation without borders enabling islet transplantation in Greece with international collaboration and innovative technology.
|
Clin Transplant
|
2013
|
0.79
|
|
81
|
Liver X Receptor (LXR) activation negatively regulates visfatin expression in macrophages.
|
Biochem Biophys Res Commun
|
2010
|
0.78
|
|
82
|
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
|
J Clin Invest
|
2015
|
0.78
|
|
83
|
The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human β-cells and its targeted inactivation impairs glucose tolerance.
|
Endocrinology
|
2013
|
0.78
|
|
84
|
Bariatric surgery, lipoprotein metabolism and cardiovascular risk.
|
Curr Opin Lipidol
|
2015
|
0.78
|
|
85
|
Human islet distribution programme for basic research: activity over the last 5 years.
|
Diabetologia
|
2015
|
0.78
|
|
86
|
Risk factors for lateral cervical lymph node involvement in follicular thyroid carcinoma.
|
World J Surg
|
2008
|
0.78
|
|
87
|
A score based on microscopic criteria proposed for analysis of papillary carcinoma of the thyroid.
|
Virchows Arch
|
2008
|
0.76
|
|
88
|
Partial graft recovery following eradication of hepatitis E virus infection after successful islet allograft transplantation.
|
Transpl Int
|
2010
|
0.76
|
|
89
|
IMPACT OF OBESITY ON ENDOTOXIN-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION.
|
Shock
|
2015
|
0.76
|
|
90
|
CpG methylation changes within the IL2RA promoter in type 1 diabetes of childhood onset.
|
PLoS One
|
2013
|
0.76
|
|
91
|
[Effects of bariatric surgery on the liver].
|
Gastroenterol Clin Biol
|
2005
|
0.75
|
|
92
|
Chylothorax: unusual complication after laparoscopic gastric banding.
|
Obes Surg
|
2009
|
0.75
|
|
93
|
Modulation of specific beta cell gene (re)expression during in vitro expansion of human pancreatic islet cells.
|
Cell Transplant
|
2003
|
0.75
|
|
94
|
Impact of Surgical Technique on Long-term Complication Rate After Laparoscopic Adjustable Gastric Banding (LAGB): Results of a Single-blinded Randomized Controlled trial (ANOSEAN Study).
|
Ann Surg
|
2016
|
0.75
|
|
95
|
Insulinoma of genetic aetiology.
|
Ann Endocrinol (Paris)
|
2013
|
0.75
|
|
96
|
Long-term Follow-up of MEN1 Patients Who Do Not Have Initial Surgery for Small ≤2 cm Nonfunctioning Pancreatic Neuroendocrine Tumors, an AFCE and GTE Study: Association Francophone de Chirurgie Endocrinienne & Groupe d'Etude des Tumeurs Endocrines.
|
Ann Surg
|
2017
|
0.75
|
|
97
|
Incidence and Predictive Factors of Postprandial Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass: A Five year Longitudinal Study.
|
Ann Surg
|
2016
|
0.75
|
|
98
|
Impact of Procedure-Related Complications on Long-term Islet Transplantation Outcome.
|
Transplantation
|
2015
|
0.75
|
|
99
|
Surgical treatment.
|
Ann Endocrinol (Paris)
|
2013
|
0.75
|
|
100
|
Preoperative Prediction of Postprandial Glycemia After Roux-en-Y Gastric Bypass.
|
Ann Surg
|
2017
|
0.75
|
|
101
|
Human Recombinant Antithrombin (ATrynsup/sup) Administration Improves Survival and Prevents Intravascular Coagulation After Intraportal Islet Transplantation in a Piglet Model.
|
Cell Transplant
|
2016
|
0.75
|