| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
|
Nat Genet
|
2008
|
6.75
|
|
2
|
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.
|
Cell
|
2004
|
5.80
|
|
3
|
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
|
Nat Genet
|
2009
|
5.29
|
|
4
|
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome.
|
Cell
|
2004
|
5.27
|
|
5
|
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
Nat Genet
|
2010
|
4.36
|
|
6
|
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
|
Nat Genet
|
2012
|
3.19
|
|
7
|
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
|
Nat Genet
|
2011
|
3.19
|
|
8
|
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
Nat Genet
|
2011
|
3.18
|
|
9
|
Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
|
Gastroenterology
|
2009
|
3.04
|
|
10
|
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
|
Nature
|
2013
|
2.74
|
|
11
|
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|
Nat Genet
|
2011
|
2.27
|
|
12
|
Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
|
Cancer Sci
|
2010
|
2.03
|
|
13
|
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
|
Hum Mol Genet
|
2011
|
1.96
|
|
14
|
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
|
Nat Genet
|
2008
|
1.73
|
|
15
|
p53RDL1 regulates p53-dependent apoptosis.
|
Nat Cell Biol
|
2003
|
1.65
|
|
16
|
Multiple loci are associated with white blood cell phenotypes.
|
PLoS Genet
|
2011
|
1.65
|
|
17
|
Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
|
Cancer Sci
|
2007
|
1.57
|
|
18
|
A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
|
Nat Genet
|
2007
|
1.57
|
|
19
|
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
|
Hum Mol Genet
|
2010
|
1.49
|
|
20
|
Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).
|
Hum Mol Genet
|
2009
|
1.46
|
|
21
|
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
|
PLoS Genet
|
2011
|
1.45
|
|
22
|
A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
|
Nat Genet
|
2012
|
1.37
|
|
23
|
Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
|
Hum Mol Genet
|
2010
|
1.25
|
|
24
|
Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
|
Cancer Res
|
2007
|
1.20
|
|
25
|
Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
|
Nat Commun
|
2012
|
1.20
|
|
26
|
Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
|
Cancer Res
|
2009
|
1.19
|
|
27
|
Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
|
PLoS One
|
2011
|
1.19
|
|
28
|
A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
|
PLoS Genet
|
2012
|
1.17
|
|
29
|
Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.
|
PLoS One
|
2012
|
1.15
|
|
30
|
Intraosseous lipoma: a clinical study of 12 patients.
|
J Orthop Sci
|
2002
|
1.14
|
|
31
|
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
|
Hum Mol Genet
|
2010
|
1.13
|
|
32
|
Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
|
Hum Mol Genet
|
2007
|
1.11
|
|
33
|
Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
|
Hum Mol Genet
|
2002
|
1.10
|
|
34
|
Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
|
Cancer Sci
|
2009
|
1.09
|
|
35
|
Dihydropyrimidinase deficiency and severe 5-fluorouracil toxicity.
|
Clin Cancer Res
|
2003
|
1.09
|
|
36
|
Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
|
Int J Cancer
|
2014
|
1.03
|
|
37
|
Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
|
PLoS Genet
|
2013
|
1.02
|
|
38
|
Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases.
|
Rheumatology (Oxford)
|
2010
|
1.01
|
|
39
|
The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
|
Genes Chromosomes Cancer
|
2012
|
1.00
|
|
40
|
No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
|
BMC Med Genet
|
2012
|
0.94
|
|
41
|
A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
|
J Hepatol
|
2013
|
0.94
|
|
42
|
Primary leiomyosarcoma of the femur.
|
J Orthop Sci
|
2002
|
0.94
|
|
43
|
Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
|
J Hum Genet
|
2011
|
0.93
|
|
44
|
C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
|
Genes Chromosomes Cancer
|
2011
|
0.92
|
|
45
|
Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway.
|
Mol Cancer Res
|
2010
|
0.91
|
|
46
|
Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
|
PLoS One
|
2013
|
0.90
|
|
47
|
Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.
|
Cancer Res
|
2012
|
0.89
|
|
48
|
CLCA2 as a p53-inducible senescence mediator.
|
Neoplasia
|
2012
|
0.89
|
|
49
|
A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
|
PLoS Genet
|
2012
|
0.88
|
|
50
|
Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population.
|
J Hum Genet
|
2011
|
0.87
|
|
51
|
Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring.
|
Anal Chem
|
2012
|
0.86
|
|
52
|
Genome wide association study of age at menarche in the Japanese population.
|
PLoS One
|
2013
|
0.85
|
|
53
|
Signals through glycoprotein 130 regulate the endothelial differentiation of cardiac stem cells.
|
Arterioscler Thromb Vasc Biol
|
2009
|
0.84
|
|
54
|
Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
|
PLoS One
|
2012
|
0.84
|
|
55
|
Crocetin, a carotenoid from Gardenia jasminoides Ellis, protects against hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
|
Phytother Res
|
2014
|
0.83
|
|
56
|
Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
|
Int J Hematol
|
2011
|
0.83
|
|
57
|
Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer.
|
Proteome Sci
|
2011
|
0.82
|
|
58
|
Contribution of membrane-associated prostaglandin E2 synthase to bone resorption.
|
J Cell Physiol
|
2003
|
0.81
|
|
59
|
A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
|
J Hum Genet
|
2013
|
0.81
|
|
60
|
Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
|
Clin Cancer Res
|
2013
|
0.80
|
|
61
|
A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
|
J Hum Genet
|
2008
|
0.80
|
|
62
|
Microfloral characterization of the tongue coating and associated risk for pneumonia-related health problems in institutionalized older adults.
|
J Am Geriatr Soc
|
2010
|
0.79
|
|
63
|
Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.
|
J Hum Genet
|
2007
|
0.79
|
|
64
|
Impact of PSCA variation on gastric ulcer susceptibility.
|
PLoS One
|
2013
|
0.78
|
|
65
|
Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia.
|
J Hum Genet
|
2013
|
0.78
|
|
66
|
Impact of four loci on serum tamsulosin hydrochloride concentration.
|
J Hum Genet
|
2012
|
0.76
|
|
67
|
Change to a preference for maltose from sucrose over days in Zn-deficient rats selecting from maltose and sucrose diets.
|
J Nutr Sci Vitaminol (Tokyo)
|
2009
|
0.75
|
|
68
|
Preference for glucose in Zn-deficient rats selecting from glucose and fructose diets.
|
J Nutr Sci Vitaminol (Tokyo)
|
2005
|
0.75
|
|
69
|
Purification and expression of a processing protease on beta-alanine-oxoglutarate aminotransferase from rat liver mitochondria.
|
FEBS Lett
|
2004
|
0.75
|
|
70
|
Fusion of magnetic resonance angiography and magnetic resonance imaging for surgical planning for meningioma--technical note.
|
Neurol Med Chir (Tokyo)
|
2008
|
0.75
|
|
71
|
Decreased preference for sucrose in rats fed a low protein diet and its intensification by zinc-deficiency.
|
J Nutr Sci Vitaminol (Tokyo)
|
2011
|
0.75
|
|
72
|
Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
|
J Bone Miner Metab
|
2008
|
0.75
|
|
73
|
Effect of fasting on methionine adenosyltransferase expression and the methionine cycle in the mouse liver.
|
J Nutr Sci Vitaminol (Tokyo)
|
2005
|
0.75
|
|
74
|
Modulation of maltose preference by selection from dextrin, maltose and glucose diets in zinc-deficient rats.
|
J Nutr Sci Vitaminol (Tokyo)
|
2008
|
0.75
|
|
75
|
L-threonine supplementation increases the amplitude of the feed intake cycle of rats fed a low-protein zinc-deficient diet.
|
J Nutr Sci Vitaminol (Tokyo)
|
2002
|
0.75
|
|
76
|
Mechanism of liver tyrosine aminotransferase increase in ethanol-treated mice and its effect on serum tyrosine level.
|
J Nutr Sci Vitaminol (Tokyo)
|
2007
|
0.75
|
|
77
|
The influence of various carbohydrates on the feeding pattern of rats fed zinc-deficient diets.
|
J Nutr Sci Vitaminol (Tokyo)
|
2003
|
0.75
|