Published in Biochem J on April 15, 1991
NetOglyc: prediction of mucin type O-glycosylation sites based on sequence context and surface accessibility. Glycoconj J (1998) 3.19
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family. Glycobiology (2011) 2.56
Glycosylation site prediction using ensembles of Support Vector Machine classifiers. BMC Bioinformatics (2007) 1.93
Enrichment of glycopeptides for glycan structure and attachment site identification. Nat Methods (2009) 1.87
Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis. Infect Immun (1995) 1.86
Prediction of O-glycosylation of mammalian proteins: specificity patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase. Biochem J (1995) 1.81
Bacterial glycoproteins: a link between glycosylation and proteolytic cleavage of a 19 kDa antigen from Mycobacterium tuberculosis. EMBO J (1996) 1.74
DC-HIL is a negative regulator of T lymphocyte activation. Blood (2007) 1.37
Affinity enrichment and characterization of mucin core-1 type glycopeptides from bovine serum. Mol Cell Proteomics (2009) 1.30
In silico platform for prediction of N-, O- and C-glycosites in eukaryotic protein sequences. PLoS One (2013) 1.29
SIRE-1, a copia/Ty1-like retroelement from soybean, encodes a retroviral envelope-like protein. Proc Natl Acad Sci U S A (1998) 1.20
Database analysis of O-glycosylation sites in proteins. Biophys J (2001) 1.15
Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus. Biochem J (1994) 1.07
Inactivation of the mouse sperm receptor, mZP3, by site-directed mutagenesis of individual serine residues located at the combining site for sperm. Proc Natl Acad Sci U S A (1998) 1.06
O-GLYCBASE version 2.0: a revised database of O-glycosylated proteins. Nucleic Acids Res (1997) 1.06
O Mannosylation of alpha-dystroglycan is essential for lymphocytic choriomeningitis virus receptor function. J Virol (2005) 1.06
The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies. Mol Immunol (2007) 1.01
Mapping the mouse ZP3 combining site for sperm by exon swapping and site-directed mutagenesis. Proc Natl Acad Sci U S A (1995) 1.01
Computational prediction of O-linked glycosylation sites that preferentially map on intrinsically disordered regions of extracellular proteins. Int J Mol Sci (2010) 0.99
How to dig deeper? Improved enrichment methods for mucin core-1 type glycopeptides. Mol Cell Proteomics (2012) 0.97
Dimer model for the microfibrillar protein fibulin-2 and identification of the connecting disulfide bridge. EMBO J (1997) 0.95
Exploiting differential dissociation chemistries of O-linked glycopeptide ions for the localization of mucin-type protein glycosylation. J Proteome Res (2009) 0.95
Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains. Biochem J (1995) 0.94
Embryonal carcinoma cells transfected with ZP3 genes differentially glycosylate similar polypeptides and secrete active mouse sperm receptor. J Cell Biol (1991) 0.92
Molecular cloning of chicken aggrecan. Structural analyses. Biochem J (1992) 0.92
Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis. Glycobiology (2014) 0.91
Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation. Proc Natl Acad Sci U S A (1993) 0.91
Expression of Arg-Gingipain RgpB is required for correct glycosylation and stability of monomeric Arg-gingipain RgpA from Porphyromonas gingivalis W50. Infect Immun (2005) 0.90
hch-1, a gene required for normal hatching and normal migration of a neuroblast in C. elegans, encodes a protein related to TOLLOID and BMP-1. EMBO J (1996) 0.89
Antibacterial peptides are present in chromaffin cell secretory granules. Cell Mol Neurobiol (1998) 0.88
Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3). Mol Cell Proteomics (2015) 0.88
PANP is a novel O-glycosylated PILRα ligand expressed in neural tissues. Biochem Biophys Res Commun (2011) 0.87
Structural features of the human salivary mucin, MUC7. Glycoconj J (1998) 0.86
Molecular cloning and biological activity of alpha-, beta-, and gamma-megaspermin, three elicitins secreted by Phytophthora megasperma H20. Plant Physiol (2003) 0.86
O-GLYCBASE: a revised database of O-glycosylated proteins. Nucleic Acids Res (1996) 0.84
Mechanisms of sperm-egg interactions: between sugars and broken bonds. Sci Signal (2010) 0.82
Polypeptide N-acetylgalactosaminyltransferase activity in tracheal epithelial microsomes. Biochem J (1992) 0.80
Influence of the amino acid sequence on the MUC5AC motif peptide O-glycosylation by human gastric UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase(s). Glycoconj J (1998) 0.80
O-GLYCBASE Version 3.0: a revised database of O-glycosylated proteins. Nucleic Acids Res (1998) 0.79
Prediction of O-glycosylation Sites Using Random Forest and GA-Tuned PSO Technique. Bioinform Biol Insights (2015) 0.78
Glycosylation of the two O-glycosylated domains of human MUC2 mucin in patients transposed with artificial urinary bladders constructed from proximal colonic tissue. Glycoconj J (2007) 0.77
Biological and biochemical properties of two Xenopus laevis N-acetylgalactosaminyltransferases with contrasting roles in embryogenesis. Comp Biochem Physiol B Biochem Mol Biol (2014) 0.76
Recent evolution of the salivary mucin MUC7. Sci Rep (2016) 0.75
UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase from the snail Biomphalaria glabrata - substrate specificity and preference of glycosylation sites. Glycoconj J (2014) 0.75
Molecular Cloning, Bioinformatic Analysis, and Expression of Bombyx mori Lebocin 5 Gene Related to Beauveria bassiana Infection. Biomed Res Int (2017) 0.75
Generation of clade- and symbiont-specific antibodies to characterize marker molecules during Cnidaria-Symbiodinium endosymbiosis. Sci Rep (2017) 0.75
Structural and functional characterization of a novel immunomodulatory glycoprotein isolated from ajowan (Trachyspermum ammi L.). Glycoconj J (2017) 0.75
A novel model to predict O-glycosylation sites using a highly unbalanced dataset. Glycoconj J (2012) 0.75
Assembly of asparagine-linked oligosaccharides. Annu Rev Biochem (1985) 26.05
Prediction of protein conformation. Biochemistry (1974) 20.51
The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell (1984) 12.54
The protein identification resource (PIR). Nucleic Acids Res (1986) 5.18
Glycoproteins. Annu Rev Biochem (1972) 5.08
Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng (1990) 4.17
Conformational preferences of amino acids in globular proteins. Biochemistry (1978) 4.00
Amino-acid sequence and oligosaccharide attachment sites of human erythrocyte glycophorin. Proc Natl Acad Sci U S A (1975) 3.67
Properties of potato lectin and the nature of its glycoprotein linkages. Biochem J (1978) 3.47
Structure and biosynthesis of the mannan component of the yeast cell envelope. Adv Microb Physiol (1976) 3.17
Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoprotein. Proc Natl Acad Sci U S A (1987) 2.70
Folding of polypeptide chains in proteins: a proposed mechanism for folding. Proc Natl Acad Sci U S A (1971) 2.68
Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum. Proc Natl Acad Sci U S A (1985) 2.64
Human apolipoprotein E. The complete amino acid sequence. J Biol Chem (1982) 2.64
Glycoproteins. Adv Protein Chem (1973) 2.56
Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. Biochemistry (1986) 2.52
The sucrase-isomaltase complex: primary structure, membrane-orientation, and evolution of a stalked, intrinsic brush border protein. Cell (1986) 2.43
Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotropin. Nature (1979) 2.36
Tyrosine sulfation is a trans-Golgi-specific protein modification. J Cell Biol (1987) 2.10
The reverse turn as a polypeptide conformation in globular proteins. Proc Natl Acad Sci U S A (1973) 2.10
Complete amino acid sequence and glycosylation sites of glycoprotein gp71A of Friend murine leukemia virus. Proc Natl Acad Sci U S A (1982) 2.06
The sequence of rat leukosialin (W3/13 antigen) reveals a molecule with O-linked glycosylation of one third of its extracellular amino acids. EMBO J (1987) 1.86
Structure at the hinge region in rabbit immunoglobulin-G. Nature (1967) 1.74
Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Proc Natl Acad Sci U S A (1987) 1.73
Subcellular organization of glycosylation in mammalian cells. Biochim Biophys Acta (1987) 1.71
Partial deletion in the heavy chain disease protein ZUC. Nature (1969) 1.65
Structure, biosynthesis, and function of glycosylphosphatidylinositols. Biochemistry (1990) 1.63
Cytochemical localization of terminal N-acetyl-D-galactosamine residues in cellular compartments of intestinal goblet cells: implications for the topology of O-glycosylation. J Cell Biol (1984) 1.61
Purification, composition, molecular weight, and subunit structure of ovine submaxillary mucin. J Biol Chem (1977) 1.60
Carbohydrate-peptide linkage in glycoproteins. Arch Biochem Biophys (1976) 1.59
Structural characterization of human erythropoietin. J Biol Chem (1986) 1.54
Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement. Biochem J (1979) 1.45
The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit. J Biol Chem (1975) 1.45
Amino acid sequence of a mouse myeloma immunoglobin heavy chain (MOPC 47 A) with a 100-residue deletion. J Biol Chem (1979) 1.43
Primary structure of a human IgA1 immunoglobulin. IV. Streptococcal IgA1 protease, digestion, Fab and Fc fragments, and the complete amino acid sequence of the alpha 1 heavy chain. J Biol Chem (1979) 1.36
Effects of glycosylation on the conformation and dynamics of O-linked glycoproteins: carbon-13 NMR studies of ovine submaxillary mucin. Biochemistry (1989) 1.36
Complete amino acid sequence of human hemopexin, the heme-binding protein of serum. Proc Natl Acad Sci U S A (1985) 1.35
Structure of human hemopexin: O-glycosyl and N-glycosyl sites and unusual clustering of tryptophan residues. Proc Natl Acad Sci U S A (1984) 1.34
N-terminal amino acid sequence of sialoglycoprotein D (glycophorin C) from human erythrocyte membranes. Eur J Biochem (1982) 1.34
Amino acid sequence of bovine protein Z: a vitamin K-dependent serine protease homolog. FEBS Lett (1985) 1.31
Initial glycosylation of proteins with acetylgalactosaminylserine linkages. Proc Natl Acad Sci U S A (1979) 1.27
Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin. J Biol Chem (1979) 1.26
Temporal aspects of the N- and O-glycosylation of human chorionic gonadotropin. J Biol Chem (1982) 1.23
The complete amino acid sequence of alanine apolipoprotein (apoC-3), and apolipoprotein from human plasma very low density lipoproteins. J Biol Chem (1974) 1.22
Bovine factor X1 (Stuart factor): amino-acid sequence of heavey chain. Proc Natl Acad Sci U S A (1975) 1.21
Glycosylation of human apolipoprotein E. The carbohydrate attachment site is threonine 194. J Biol Chem (1989) 1.18
Amino acid sequence and post-translational modification of human interleukin 2. Proc Natl Acad Sci U S A (1984) 1.13
Characterization of a complementary deoxyribonucleic acid coding for human and bovine plasminogen. Biochemistry (1984) 1.13
Complete amino acid sequence of human alpha 1-microglobulin. Biochem Biophys Res Commun (1981) 1.13
Ovine submaxillary mucin. Primary structure and peptide substrates of UDP-N-acetylgalactosamine:mucin transferase. J Biol Chem (1977) 1.12
Amino acid sequence of the sex steroid binding protein of human blood plasma. Biochemistry (1986) 1.11
Partial cDNA sequence encoding a nuclear pore protein modified by O-linked N-acetylglucosamine. Proc Natl Acad Sci U S A (1988) 1.10
The complete amino acid sequence of echinoidin, a lectin from the coelomic fluid of the sea urchin Anthocidaris crassispina. Homologies with mammalian and insect lectins. J Biol Chem (1987) 1.10
Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, V. Attachments of carbohydrates in the human urinary trypsin inhibitor isolated by affinity chromatography. Hoppe Seylers Z Physiol Chem (1981) 1.03
Oligosaccharides at individual glycosylation sites in glycoprotein 71 of Friend murine leukemia virus. Eur J Biochem (1990) 1.02
Investigation of the requirements for O-glycosylation by bovine submaxillary gland UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosamine transferase using synthetic peptide substrates. J Biol Chem (1981) 1.01
Glycophorins B and C from human erythrocyte membranes. Purification and sequence analysis. J Biol Chem (1987) 1.00
Structural characterization of natural and recombinant human granulocyte colony-stimulating factors. J Biochem (1990) 1.00
Complete amino acid sequence of the delta heavy chain of human immunoglobulin D. Proc Natl Acad Sci U S A (1982) 0.99
Two-domain structure of the native and reactive centre cleaved forms of C1 inhibitor of human complement by neutron scattering. J Mol Biol (1990) 0.95
Characterization of the B-chain of human plasma alpha 2HS-glycoprotein. The complete amino acid sequence and primary structure of its heteroglycan. J Biol Chem (1983) 0.95
Characterization of a glucoamylase G2 from Aspergillus niger. Eur J Biochem (1986) 0.95
Completion of the primary structure of human high-molecular-mass kininogen. The amino acid sequence of the entire heavy chain and evidence for its evolution by gene triplication. Eur J Biochem (1986) 0.95
Temporal aspects of O-glycosylation and cell surface expression of ascites sialoglycoprotein-1, the major cell surface sialomucin of 13762 mammary ascites tumor cells. J Biol Chem (1987) 0.94
Amino acid sequence and attachment sites of oligosaccharide units of porcine erythrocyte glycophorin. J Biochem (1980) 0.92
The amino acid sequence of the light chain of human high-molecular-mass kininogen. Eur J Biochem (1985) 0.91
Structural determination of the oligosaccharide side chains from a glycoprotein isolated from the mucus of the coral Acropora formosa. J Biol Chem (1987) 0.91
The complete amino acid sequence of the A-chain of human plasma alpha 2HS-glycoprotein. J Biol Chem (1986) 0.90
Primary structure of a deleted human lambda type immunoglobulin light chain containing carbohydrate: protein Sm lambda. Proc Natl Acad Sci U S A (1975) 0.89
O-glycosylation of leukosialin in K562 cells. Evidence for initiation and elongation in early Golgi compartments. Eur J Biochem (1989) 0.88
Carbohydrate of the human plasminogen variants. III. Structure of the O-glycosidically linked oligosaccharide unit. J Biol Chem (1979) 0.88
Recombinant human erythropoietin: purification and analysis of carbohydrate linkage. Arch Biochem Biophys (1988) 0.88
Complete amino acid sequence of bovine plasminogen. Comparison with human plasminogen. Eur J Biochem (1985) 0.86
O-linked glycosylation of rat renal gamma-glutamyltranspeptidase adjacent to its membrane anchor domain. J Biol Chem (1989) 0.86
New variant of low density lipoprotein receptor gene. FH-Tonami. Arteriosclerosis (1988) 0.85
Complete amino acid sequence of a human pituitary glycopeptide: an important maturation product of pro-opiomelanocortin. Proc Natl Acad Sci U S A (1981) 0.85
Polysialoglycoproteins of Salmonidae fish eggs. Complete structure of 200-kDa polysialoglycoprotein from the unfertilized eggs of rainbow trout (Salmo gairdneri). J Biol Chem (1986) 0.84
Primary structure of horse erythrocyte glycophorin HA. Its amino acid sequence has a unique homology with those of human and porcine erythrocyte glycophorins. J Membr Biol (1982) 0.84
Amino acid sequence of galactosamine-containing glycopeptides in the hinge region of a human immunoglobulin D. Biochem Biophys Res Commun (1982) 0.82
An oligosaccharide of the O-linked type distinguishes the free from the combined form of hCG alpha subunit. Biochem Biophys Res Commun (1984) 0.82
Structures of sialylated O-glycosidically and N-glycosidically linked oligosaccharides in a monoclonal immunoglobulin light chain. J Biol Chem (1981) 0.81
Structure of the 22-residue somatostatin from catfish. An O-glycosylated peptide having multiple forms. J Biol Chem (1984) 0.80
Biogenesis of glycophorin A in K562 human erythroleukemia cells. J Biol Chem (1987) 0.79
Substrate recognition by UDP-N-acetyl-alpha-D-galactosamine: polypeptide n-acetyl-alpha-D-galactosaminyltransferase. Effects of chain length and disulphide bonding of synthetic peptide substrates. Carbohydr Res (1988) 0.79
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol (2001) 66.87
Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng (1997) 38.38
A new method for predicting signal sequence cleavage sites. Nucleic Acids Res (1986) 37.19
Patterns of amino acids near signal-sequence cleavage sites. Eur J Biochem (1983) 26.68
Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J Mol Biol (2000) 22.77
Signal sequences. The limits of variation. J Mol Biol (1985) 21.24
A hidden Markov model for predicting transmembrane helices in protein sequences. Proc Int Conf Intell Syst Mol Biol (1998) 14.18
How signal sequences maintain cleavage specificity. J Mol Biol (1984) 11.03
TopPred II: an improved software for membrane protein structure predictions. Comput Appl Biosci (1994) 10.03
ChloroP, a neural network-based method for predicting chloroplast transit peptides and their cleavage sites. Protein Sci (1999) 9.82
Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Eng (1997) 8.25
Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms. Protein Sci (1998) 7.88
A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Int J Neural Syst (1999) 7.40
Mitochondrial targeting sequences may form amphiphilic helices. EMBO J (1986) 7.11
Machine learning approaches for the prediction of signal peptides and other protein sorting signals. Protein Eng (1999) 6.72
Sequence determinants of cytosolic N-terminal protein processing. Eur J Biochem (1986) 5.59
Topogenic signals in integral membrane proteins. Eur J Biochem (1988) 5.16
A conserved cleavage-site motif in chloroplast transit peptides. FEBS Lett (1990) 4.25
Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng (1990) 4.17
How proteins adapt to a membrane-water interface. Trends Biochem Sci (2000) 3.76
Trans-membrane translocation of proteins. The direct transfer model. Eur J Biochem (1979) 3.13
Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane. J Biol Chem (1993) 3.02
Predicting the topology of eukaryotic membrane proteins. Eur J Biochem (1993) 2.73
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J (2000) 2.70
Membrane proteins: the amino acid composition of membrane-penetrating segments. Eur J Biochem (1981) 2.52
Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells. EMBO J (1984) 2.43
Cleavage-site motifs in mitochondrial targeting peptides. Protein Eng (1990) 2.38
The Escherichia coli SRP and SecB targeting pathways converge at the translocon. EMBO J (1998) 2.35
A receptor component of the chloroplast protein translocation machinery. Science (1994) 2.34
Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli. FEBS Lett (2001) 2.28
Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids. Cell (1990) 2.24
On the hydrophobic nature of signal sequences. Eur J Biochem (1981) 2.01
Competition between Sec- and TAT-dependent protein translocation in Escherichia coli. EMBO J (1999) 1.95
Prediction of organellar targeting signals. Biochim Biophys Acta (2001) 1.93
Structures of N-terminally acetylated proteins. Eur J Biochem (1985) 1.92
Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle. FEBS Lett (1996) 1.89
Topology, subcellular localization, and sequence diversity of the Mlo family in plants. J Biol Chem (1999) 1.88
Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor. Mol Microbiol (1997) 1.85
Net N-C charge imbalance may be important for signal sequence function in bacteria. J Mol Biol (1986) 1.85
Topological rules for membrane protein assembly in eukaryotic cells. J Biol Chem (1997) 1.83
Anionic phospholipids are determinants of membrane protein topology. EMBO J (1997) 1.77
Molecular mechanism of membrane protein integration into the endoplasmic reticulum. Cell (1997) 1.70
Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli. Proc Natl Acad Sci U S A (1998) 1.62
Topological "frustration" in multispanning E. coli inner membrane proteins. Cell (1994) 1.59
Consensus predictions of membrane protein topology. FEBS Lett (2000) 1.55
Membrane protein topology: effects of delta mu H+ on the translocation of charged residues explain the 'positive inside' rule. EMBO J (1994) 1.53
Translation rate modification by preferential codon usage: intragenic position effects. J Theor Biol (1987) 1.51
A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain. J Biol Chem (1996) 1.51
The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane. Biochemistry (1999) 1.49
Towards a comparative anatomy of N-terminal topogenic protein sequences. J Mol Biol (1986) 1.46
Chloroplast transit peptides from the green alga Chlamydomonas reinhardtii share features with both mitochondrial and higher plant chloroplast presequences. FEBS Lett (1990) 1.45
A 30-residue-long "export initiation domain" adjacent to the signal sequence is critical for protein translocation across the inner membrane of Escherichia coli. Proc Natl Acad Sci U S A (1991) 1.43
The distribution of charged amino acids in mitochondrial inner-membrane proteins suggests different modes of membrane integration for nuclearly and mitochondrially encoded proteins. Eur J Biochem (1992) 1.42
Sec dependent and sec independent assembly of E. coli inner membrane proteins: the topological rules depend on chain length. EMBO J (1993) 1.41
Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides. Proteins (1998) 1.41
The 'positive-inside rule' applies to thylakoid membrane proteins. FEBS Lett (1991) 1.40
The COOH-terminal ends of internal signal and signal-anchor sequences are positioned differently in the ER translocase. J Cell Biol (1994) 1.39
Architecture of helix bundle membrane proteins: an analysis of cytochrome c oxidase from bovine mitochondria. Protein Sci (1997) 1.38
Determination of the border between the transmembrane and cytoplasmic domains of human integrin subunits. J Biol Chem (1999) 1.37
A turn propensity scale for transmembrane helices. J Mol Biol (1999) 1.37
Signal sequences are not uniformly hydrophobic. J Mol Biol (1982) 1.37
Turns in transmembrane helices: determination of the minimal length of a "helical hairpin" and derivation of a fine-grained turn propensity scale. J Mol Biol (1999) 1.36
Life and death of a signal peptide. Nature (1998) 1.35
Stop-transfer function of pseudo-random amino acid segments during translocation across prokaryotic and eukaryotic membranes. Eur J Biochem (1998) 1.34
Different conformations of nascent polypeptides during translocation across the ER membrane. BMC Cell Biol (2000) 1.34
Defining a similarity threshold for a functional protein sequence pattern: the signal peptide cleavage site. Proteins (1996) 1.31
Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. J Mol Biol (1998) 1.27
Proline-induced disruption of a transmembrane alpha-helix in its natural environment. J Mol Biol (1998) 1.26
A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane. J Biol Chem (1996) 1.25
Glycosylation efficiency of Asn-Xaa-Thr sequons depends both on the distance from the C terminus and on the presence of a downstream transmembrane segment. J Biol Chem (2000) 1.25
Properties of N-terminal tails in G-protein coupled receptors: a statistical study. Protein Eng (1995) 1.25
Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins. Mol Cell (1998) 1.25
Why mitochondria need a genome. FEBS Lett (1986) 1.23
Divergent evolution of membrane protein topology: the Escherichia coli RnfA and RnfE homologues. Proc Natl Acad Sci U S A (1999) 1.22
Sec-independent translocation of a 100-residue periplasmic N-terminal tail in the E. coli inner membrane protein proW. EMBO J (1994) 1.21
Prediction of N-terminal protein sorting signals. Curr Opin Struct Biol (1997) 1.18
Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix: a rapid way to map helix-helix interactions in integral membrane proteins. Protein Sci (1996) 1.15
Membrane topology of the 60-kDa Oxa1p homologue from Escherichia coli. J Biol Chem (1998) 1.14
Positively charged amino acids placed next to a signal sequence block protein translocation more efficiently in Escherichia coli than in mammalian microsomes. Mol Gen Genet (1993) 1.13
Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli. J Biol Chem (1992) 1.10
Mapping of catalytically important domains in Escherichia coli leader peptidase. EMBO J (1990) 1.08
Homology to region X from staphylococcal protein A is not unique to cell surface proteins. J Theor Biol (1987) 1.07
Phosphatidylethanolamine mediates insertion of the catalytic domain of leader peptidase in membranes. FEBS Lett (1998) 1.04
Analysis and prediction of mitochondrial targeting peptides. Methods Cell Biol (2001) 1.02
Three-dimensional model for the membrane domain of Escherichia coli leader peptidase based on disulfide mapping. Biochemistry (1993) 1.02
Do protein-lipid interactions determine the recognition of transmembrane helices at the ER translocon? Biochem Soc Trans (2005) 1.01
Distant downstream sequence determinants can control N-tail translocation during protein insertion into the endoplasmic reticulum membrane. J Biol Chem (2000) 1.01
Architecture of beta-barrel membrane proteins: analysis of trimeric porins. Protein Sci (1998) 1.00
A signal peptide with a proline next to the cleavage site inhibits leader peptidase when present in a sec-independent protein. FEBS Lett (1992) 1.00
Trans-membrane translocation of proteins. A detailed physico-chemical analysis. Eur J Biochem (1980) 1.00
De novo design of integral membrane proteins. Nat Struct Biol (1994) 0.99
Directionality in protein translocation across membranes: the N-tail phenomenon. Trends Cell Biol (1995) 0.98
Inhibition of protein translocation across the endoplasmic reticulum membrane by sterols. J Biol Chem (2001) 0.95
Membrane topology of Kch, a putative K+ channel from Escherichia coli. J Biol Chem (1996) 0.94
Breaking the camel's back: proline-induced turns in a model transmembrane helix. J Mol Biol (1998) 0.93
The internal repeats in the Na+/Ca2+ exchanger-related Escherichia coli protein YrbG have opposite membrane topologies. J Biol Chem (2001) 0.93
Alanine insertion scanning mutagenesis of lactose permease transmembrane helices. J Biol Chem (1997) 0.92
In vitro membrane integration of leader peptidase depends on the Sec machinery and anionic phospholipids and can occur post-translationally. FEBS Lett (1997) 0.91
N-tail translocation in a eukaryotic polytopic membrane protein: synergy between neighboring transmembrane segments. Eur J Biochem (1999) 0.91
A de novo designed signal peptide cleavage cassette functions in vivo. J Biol Chem (1991) 0.91