A novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer disease.

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Published in Alzheimers Res Ther on March 29, 2010

Authors

Erik Portelius1, Robert A Dean, Mikael K Gustavsson, Ulf Andreasson, Henrik Zetterberg, Eric Siemers, Kaj Blennow

Author Affiliations

1: Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Molndal, SE-431 80, Sweden. erik.portelius@neuro.gu.se.

Associated clinical trials:

Effects of LY450139 Dihydrate on Subjects With Mild to Moderate Alzheimer's Disease | NCT00244322

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