Published in Plant Biotechnol J on October 01, 2010
Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana. Plant Biotechnol J (2011) 1.21
A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge. Proc Natl Acad Sci U S A (2011) 1.21
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proc Natl Acad Sci U S A (2010) 1.20
Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis. Plant Physiol (2011) 0.96
Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue. Biotechnol J (2013) 0.93
Evolution of plant-made pharmaceuticals. Int J Mol Sci (2011) 0.85
Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana. Plant Biotechnol J (2014) 0.81
Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity. Chem Biol Interact (2012) 0.80
The Arabidopsis thaliana ortholog of a purported maize cholinesterase gene encodes a GDSL-lipase. Plant Mol Biol (2013) 0.80
Semicontinuous Bioreactor Production of Recombinant Butyrylcholinesterase in Transgenic Rice Cell Suspension Cultures. Front Plant Sci (2016) 0.79
Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction. Future Med Chem (2012) 0.79
Biological and biochemical characterization of HIV-1 Gag/dgp41 virus-like particles expressed in Nicotiana benthamiana. Plant Biotechnol J (2013) 0.79
Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana. Front Plant Sci (2016) 0.78
Anti-infective immunoadhesins from plants. Plant Biotechnol J (2015) 0.78
Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system. Acta Naturae (2013) 0.78
Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase. PLoS One (2013) 0.75
Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse. BMC Biotechnol (2016) 0.75
Function of alternative splicing. Gene (2004) 5.95
Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression. Bioinformatics (2004) 2.47
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity (2009) 2.33
RACK1 has the nerve to act: structure meets function in the nervous system. Prog Neurobiol (2006) 1.56
Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO Mol Med (2013) 1.54
Chronic cholinergic imbalances promote brain diffusion and transport abnormalities. FASEB J (2005) 1.50
A network-based method for predicting disease-causing genes. J Comput Biol (2009) 1.49
MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leuk Res (2005) 1.49
Virtues and woes of AChE alternative splicing in stress-related neuropathologies. Trends Neurosci (2006) 1.45
Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science (2002) 1.39
STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma. PLoS One (2012) 1.33
Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol (2002) 1.28
Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. J Biol Chem (2009) 1.23
Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products. J Biol Chem (2004) 1.20
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proc Natl Acad Sci U S A (2010) 1.20
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proc Natl Acad Sci U S A (2012) 1.16
Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci (2009) 1.16
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study. Proc Natl Acad Sci U S A (2004) 1.09
Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. EMBO Mol Med (2012) 1.09
The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. FASEB J (2003) 1.08
Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci U S A (2006) 1.08
Hedgehog signaling pathway molecules and ALDH1A1 expression in early-stage non-small cell lung cancer. Lung Cancer (2011) 1.08
Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell Tissue Res (2006) 1.07
Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. Proc Natl Acad Sci U S A (2002) 1.07
Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain (2007) 1.06
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol (2005) 1.05
A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs. Proc Natl Acad Sci U S A (2004) 1.04
Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortality. Mol Med (2010) 1.04
Pre-mRNA splicing modulations in senescence. Aging Cell (2002) 1.03
Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements. Eur J Biochem (2002) 1.02
Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649-684), a mucosal subunit HIV/AIDS vaccine candidate. Vaccine (2006) 1.00
Purification of transgenic plant-derived recombinant human acetylcholinesterase-R. Chem Biol Interact (2005) 0.98
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. PLoS One (2008) 0.98
MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease. Inflamm Bowel Dis (2013) 0.97
Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes. Neurodegener Dis (2011) 0.96
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice. Curr Alzheimer Res (2005) 0.96
Gene-environment interactions in sporadic Parkinson's disease. J Neurochem (2006) 0.95
Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma. PLoS One (2012) 0.95
Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR. Plant Biotechnol J (2008) 0.95
Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia (2012) 0.95
Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Front Mol Neurosci (2013) 0.94
The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology. J Biol Chem (2009) 0.94
Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease. FASEB J (2005) 0.93
Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease. J Mol Neurosci (2013) 0.93
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses. J Immunol (2006) 0.93
Global coevolution of human microRNAs and their target genes. Mol Biol Evol (2014) 0.93
Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue. Biotechnol J (2013) 0.93
Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patients. J Neuroimmunol (2008) 0.92
The stress-associated acetylcholinesterase variant AChE-R is expressed in human CD34(+) hematopoietic progenitors and its C-terminal peptide ARP promotes their proliferation. Exp Hematol (2002) 0.91
Erythropoietin attenuates hyperoxia-induced oxidative stress in the developing rat brain. Brain Behav Immun (2009) 0.91
Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults. Toxicology (2006) 0.91
Cholinesterase-Targeting microRNAs Identified in silico Affect Specific Biological Processes. Front Mol Neurosci (2011) 0.90
Heterogeneous nuclear ribonucleoprotein A1 in health and neurodegenerative disease: from structural insights to post-transcriptional regulatory roles. Mol Cell Neurosci (2012) 0.90
Aging reduces glycerol-3-phosphate acyltransferase activity in activated rat splenic T-lymphocytes. Biochim Biophys Acta (2005) 0.90
Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions. Front Mol Neurosci (2012) 0.90
RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons. Neurodegener Dis (2005) 0.89
Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma "readthrough" acetylcholinesterase. J Mol Neurosci (2003) 0.89
Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome. PLoS One (2011) 0.89
Antisense treatment for myasthenia gravis: experience with monarsen. Ann N Y Acad Sci (2008) 0.88
Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis. Front Mol Neurosci (2012) 0.88
Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development. Cereb Cortex (2005) 0.88
Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath. FASEB J (2007) 0.88
Complex regulation of acetylcholinesterase gene expression in human brain tumors. Oncogene (2002) 0.88
Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex. J Neurosci (2013) 0.88
Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation. Curr Alzheimer Res (2012) 0.88
Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis. Blood (2005) 0.87
Alanine-to-threonine substitutions and amyloid diseases: butyrylcholinesterase as a case study. Chem Biol Interact (2010) 0.87
Runx1/AML1 in leukemia: disrupted association with diverse protein partners. Leuk Res (2002) 0.87
Inherited and acquired interactions between ACHE and PON1 polymorphisms modulate plasma acetylcholinesterase and paraoxonase activities. J Neurochem (2005) 0.87
Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load. Curr Alzheimer Res (2013) 0.87
AChE and RACK1 promote the anti-inflammatory properties of fluoxetine. J Mol Neurosci (2013) 0.87
Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons. J Neurosci (2004) 0.87
DNA methylation in multiple myeloma is weakly associated with gene transcription. PLoS One (2012) 0.87
Predictors for poststroke outcomes: the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study protocol. Int J Stroke (2011) 0.86
The thymic theme of acetylcholinesterase splice variants in myasthenia gravis. Blood (2007) 0.86
CREB regulates AChE-R-induced proliferation of human glioblastoma cells. Neoplasia (2004) 0.86
Long insert whole genome sequencing for copy number variant and translocation detection. Nucleic Acids Res (2013) 0.86
Modulated splicing-associated gene expression in P19 cells expressing distinct acetylcholinesterase splice variants. J Neurochem (2006) 0.85
Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes. Curr HIV Res (2008) 0.85
The structural basis of amyloid formation. Curr Alzheimer Res (2008) 0.85
Cellular stress reactions as putative cholinergic links in Alzheimer's disease. Neurochem Res (2005) 0.85
microRNAs in nociceptive circuits as predictors of future clinical applications. Front Mol Neurosci (2013) 0.85
Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure. FASEB J (2006) 0.84
Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways. Neurobiol Dis (2011) 0.84
Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations. Neurobiol Dis (2010) 0.84
Tailoring tyrosine kinase inhibitors to fit the lung cancer genome. Transl Oncol (2011) 0.83
The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice. Behav Brain Res (2008) 0.83