Published in PLoS One on March 26, 2010
Role of the gut in lipid homeostasis. Physiol Rev (2012) 1.73
Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet (2010) 1.40
Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells. J Lipid Res (2011) 1.01
Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages. Int J Mol Med (2015) 0.77
Circulating CD36 is reduced in HNF1A-MODY carriers. PLoS One (2013) 0.76
Therapeutic Potential of Dietary Phenolic Acids. Adv Pharmacol Sci (2015) 0.76
Expression of human hepatic lipase negatively impacts apolipoprotein A-I production in primary hepatocytes from Lipc-null mice. J Biomed Res (2014) 0.75
Sirtuins and nonalcoholic fatty liver disease. World J Gastroenterol (2016) 0.75
The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest (1955) 31.08
Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts. Proc Natl Acad Sci U S A (1976) 6.38
Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J Biol Chem (2004) 4.89
A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem (1999) 4.61
HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. Cell Metab (2008) 4.34
CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal (2009) 3.77
Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins. J Intern Med (2008) 3.38
CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima. J Clin Invest (2008) 3.29
Lipid droplets in lipogenesis and lipolysis. Endocrinology (2008) 3.02
ATP-Binding cassette cholesterol transporters and cardiovascular disease. Circ Res (2006) 2.64
Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL. J Mol Med (Berl) (2006) 2.57
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest (1995) 2.48
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology (2007) 2.43
Diabetic dyslipidemia. Endocrinol Metab Clin North Am (2006) 2.35
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J Clin Invest (2005) 2.04
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL. J Lipid Res (1998) 1.97
Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice. J Biol Chem (1999) 1.85
A role for lipid droplets in inter-membrane lipid traffic. Proteomics (2009) 1.77
Cellular fatty acid uptake: a pathway under construction. Trends Endocrinol Metab (2009) 1.70
Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. J Biol Chem (1999) 1.64
Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking. J Clin Invest (2008) 1.51
Adipophilin enhances lipid accumulation and prevents lipid efflux from THP-1 macrophages: potential role in atherogenesis. Arterioscler Thromb Vasc Biol (2004) 1.48
Regulation of reverse cholesterol transport and clinical implications. Am J Cardiol (2003) 1.44
The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease. J Biol Chem (2004) 1.44
CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. J Biol Chem (2008) 1.41
Scavenger receptor class B, type I-mediated [3H]cholesterol efflux to high and low density lipoproteins is dependent on lipoprotein binding to the receptor. J Biol Chem (2000) 1.37
Scavenger receptor BI: a scavenger receptor with a mission to transport high density lipoprotein lipids. Curr Opin Lipidol (2004) 1.37
CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance. J Lipid Res (2005) 1.35
ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity. J Biol Chem (2002) 1.35
A targeted apolipoprotein B-38.9-producing mutation causes fatty livers in mice due to the reduced ability of apolipoprotein B-38.9 to transport triglycerides. J Biol Chem (2000) 1.33
PXR and CAR in energy metabolism. Trends Endocrinol Metab (2009) 1.33
Endocytosis of oxidized low density lipoprotein through scavenger receptor CD36 utilizes a lipid raft pathway that does not require caveolin-1. J Biol Chem (2003) 1.24
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. J Clin Invest (2007) 1.22
CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress. J Biol Chem (2008) 1.16
Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI. J Lipid Res (2007) 1.15
Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice. Proc Natl Acad Sci U S A (1999) 1.13
Peroxisome proliferator activated receptors and lipoprotein metabolism. PPAR Res (2008) 1.12
TIP47, a lipid cargo protein involved in macrophage triglyceride metabolism. Arterioscler Thromb Vasc Biol (2009) 1.03
Quantitative analysis of ABCA1-dependent compartmentalization and trafficking of apolipoprotein A-I: implications for determining cellular kinetics of nascent high density lipoprotein biogenesis. J Biol Chem (2008) 0.98
Rab-regulated membrane traffic between adiposomes and multiple endomembrane systems. Methods Enzymol (2008) 0.98
SR-BI mediates cholesterol efflux via its interactions with lipid-bound ApoE. Structural mutations in SR-BI diminish cholesterol efflux. Biochemistry (2005) 0.97
CD36 in atherosclerosis. The role of a class B macrophage scavenger receptor. Ann N Y Acad Sci (2000) 0.96
CD36 does not play a direct role in HDL or LDL metabolism. J Lipid Res (2001) 0.94
Uptake and utilization of lipoprotein cholesteryl esters by rat granulosa cells. Biochim Biophys Acta (1990) 0.92
Mouse CD36 has opposite effects on LDL and oxidized LDL metabolism in vivo. Arterioscler Thromb Vasc Biol (2008) 0.90
Transcriptional regulation of the apolipoprotein AI gene. Front Biosci (2003) 0.86
Absence of hyperlipidemia in LDL receptor-deficient mice having apolipoprotein B100 without the putative receptor-binding sequences. Arterioscler Thromb Vasc Biol (2008) 0.83
Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages. Arterioscler Thromb Vasc Biol (2009) 0.83
Cholesterol and phospholipid efflux from cultured cells. Methods (2005) 0.79
Maturation of apolipoprotein A-I: unrecognized health benefit or a forgotten rudiment? J Lipid Res (2009) 0.78
Apolipoprotein E gene expression is reduced in apolipoprotein A-I transgenic mice. Mol Cell Biochem (2000) 0.76
9-cis-retinoic acid increases apolipoprotein AI secretion and mRNA expression in HepG2 cells. Atherosclerosis (1995) 0.76
CD36 is significantly correlated with adipophilin in human carotid lesions and inversely correlated with plasma ApoAI. J Biomed Biotechnol (2008) 0.76
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol (2005) 5.80
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A (2009) 5.64
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway. Cell Metab (2006) 3.66
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome. Cell Metab (2006) 3.38
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature (2012) 3.35
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab (2010) 2.63
1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus. Circulation (2009) 2.36
Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice. J Clin Invest (2002) 2.30
A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes. Cell Metab (2005) 2.14
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J Clin Invest (2005) 2.04
CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine. J Biol Chem (2007) 2.02
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis. J Biol Chem (2002) 1.90
Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice. J Biol Chem (2006) 1.80
Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways. J Lipid Res (2008) 1.80
Evidence against the presence of an anandamide transporter. Proc Natl Acad Sci U S A (2003) 1.76
Implications of vitamin D deficiency in pregnancy and lactation. Am J Obstet Gynecol (2009) 1.76
Cellular fatty acid uptake: a pathway under construction. Trends Endocrinol Metab (2009) 1.70
CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine. Gastroenterology (2006) 1.67
Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis. Diabetes (2008) 1.61
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res (2011) 1.60
Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology (2013) 1.57
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis. Cell Metab (2012) 1.56
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet (2004) 1.56
High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation. Endocrinology (2003) 1.53
Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype. J Biol Chem (2007) 1.53
Role of CD36 in membrane transport of long-chain fatty acids. Curr Opin Clin Nutr Metab Care (2002) 1.51
Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation. J Biol Chem (2012) 1.50
Fatty acid transport across membranes: relevance to nutrition and metabolic pathology. Annu Rev Nutr (2002) 1.42
CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. J Biol Chem (2008) 1.41
Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization. J Biol Chem (2009) 1.41
CD36-facilitated fatty acid uptake inhibits leptin production and signaling in adipose tissue. Diabetes (2007) 1.41
Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet (2010) 1.40
Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease. Cell Metab (2007) 1.38
A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice. J Lipid Res (2010) 1.36
Luminal lipid regulates CD36 levels and downstream signaling to stimulate chylomicron synthesis. J Biol Chem (2011) 1.30
Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice. J Biol Chem (2009) 1.28
Keratin 8 phosphorylation by p38 kinase regulates cellular keratin filament reorganization: modulation by a keratin 1-like disease causing mutation. J Biol Chem (2002) 1.25
Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes. Diabetes (2006) 1.25
Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes (2005) 1.24
Opposite regulation of CD36 ubiquitination by fatty acids and insulin: effects on fatty acid uptake. J Biol Chem (2008) 1.22
Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake. J Biol Chem (2010) 1.22
FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms. J Biol Chem (2005) 1.17
CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2. J Biol Chem (2011) 1.17
The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2. Genes Dev (2011) 1.17
CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress. J Biol Chem (2008) 1.16
CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness. Diabetes (2004) 1.15
Hepatic fatty acid synthesis is suppressed in mice with fatty livers due to targeted apolipoprotein B38.9 mutation. Arterioscler Thromb Vasc Biol (2002) 1.15
A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER. J Lipid Res (2010) 1.12
Hepatic triglyceride contents are genetically determined in mice: results of a strain survey. Am J Physiol Gastrointest Liver Physiol (2004) 1.12
Disruption of hedgehog signaling reveals a novel role in intestinal morphogenesis and intestinal-specific lipid metabolism in mice. Gastroenterology (2002) 1.12
Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice. J Lipid Res (2009) 1.12
Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense systems in testicular rat Leydig cells. J Steroid Biochem Mol Biol (2004) 1.11
Muscle-specific overexpression of CD36 reverses the insulin resistance and diabetes of MKR mice. Endocrinology (2004) 1.10
CD36 genetics and the metabolic complications of obesity. Curr Opin Clin Nutr Metab Care (2011) 1.08
Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem (2003) 1.08
Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation. J Biol Chem (2010) 1.08
Dimerization of the scavenger receptor class B type I: formation, function, and localization in diverse cells and tissues. J Lipid Res (2003) 1.07
Pharmacological activation of PPARbeta promotes rapid and calcineurin-dependent fiber remodeling and angiogenesis in mouse skeletal muscle. Am J Physiol Endocrinol Metab (2008) 1.06
Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism. Annu Rev Nutr (2014) 1.06
Vitamin D deficiency induces high blood pressure and accelerates atherosclerosis in mice. PLoS One (2013) 1.05
Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. Mol Cell Biochem (2006) 1.05
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. J Lipid Res (2012) 1.05
Beta3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice. Proc Natl Acad Sci U S A (2003) 1.05
Sulfo-N-succinimidyl oleate (SSO) inhibits fatty acid uptake and signaling for intracellular calcium via binding CD36 lysine 164: SSO also inhibits oxidized low density lipoprotein uptake by macrophages. J Biol Chem (2013) 1.04
Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients. J Biol Chem (2012) 1.02
Changes in taste perception and eating behavior after bariatric surgery-induced weight loss in women. Obesity (Silver Spring) (2013) 1.02
MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells. Mol Cell Biol (2012) 1.01
PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy. J Mol Cell Cardiol (2008) 1.01
PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells. J Lipid Res (2002) 1.00
1,25(OH)2 vitamin D suppresses macrophage migration and reverses atherogenic cholesterol metabolism in type 2 diabetic patients. J Steroid Biochem Mol Biol (2013) 1.00
Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport. Biol Reprod (2003) 1.00
PPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans. Am J Physiol Endocrinol Metab (2006) 1.00
CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin. FASEB J (2012) 0.99
Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway. J Endocrinol (2008) 0.98
CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting. J Biol Chem (2012) 0.98
Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis. Mol Endocrinol (2003) 0.98
Insulin and AMPK regulate FA translocase/CD36 plasma membrane recruitment in cardiomyocytes via Rab GAP AS160 and Rab8a Rab GTPase. J Lipid Res (2012) 0.97
Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids. Proc Natl Acad Sci U S A (2003) 0.97
Ablation of vimentin results in defective steroidogenesis. Endocrinology (2012) 0.96
Glucose transporter-8 (GLUT8) mediates glucose intolerance and dyslipidemia in high-fructose diet-fed male mice. Mol Endocrinol (2013) 0.96
New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36. Biochem J (2002) 0.95
CD36 level and trafficking are determinants of lipolysis in adipocytes. FASEB J (2012) 0.95
Insulin sensitivity is not associated with palmitoleate availability in obese humans. J Lipid Res (2011) 0.95
Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle. Arterioscler Thromb Vasc Biol (2013) 0.95
Intestinal lipoprotein assembly in apobec-1-/- mice reveals subtle alterations in triglyceride secretion coupled with a shift to larger lipoproteins. Am J Physiol Gastrointest Liver Physiol (2003) 0.94
Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone. J Biol Chem (2002) 0.94
Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal. J Biol Chem (2003) 0.94
Adrenal neutral cholesteryl ester hydrolase: identification, subcellular distribution, and sex differences. Endocrinology (2002) 0.93
Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation. PLoS One (2011) 0.93
Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation. Proc Natl Acad Sci U S A (2012) 0.93
Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis. J Biol Chem (2014) 0.93