Pharmacokinetic-pharmacodynamic-model-guided doripenem dosing in critically ill patients.

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Published in Antimicrob Agents Chemother on April 12, 2010

Authors

Mahesh N Samtani1, Robert Flamm, Koné Kaniga, Partha Nandy

Author Affiliations

1: Clinical Pharmacology, Advanced PK/PD Modeling and Simulation, Johnson & Johnson Pharmaceutical Research & Development, LLC, Titusville, NJ 08560, USA.

Associated clinical trials:

To Compare Safety and Efficacy of Doripenem Versus Imipenem-Cilastatin in Patients With Ventilator-Associated Pneumonia | NCT00589693

An Effectiveness, Safety, and Microbiology Study of Doripenem in Patients With Nosocomial (Hospital-acquired) Pneumonia | NCT00502801

A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia | NCT00515034

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