DNA vaccination strategies for anti-tumour effective gene therapy protocols.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 20390416)

Published in Cancer Immunol Immunother on October 01, 2010

Authors

Emanuela Signori1, Sandra Iurescia, Emanuela Massi, Daniela Fioretti, Pieranna Chiarella, Mariangela De Robertis, Monica Rinaldi, Giancarlo Tonon, Vito Michele Fazio

Author Affiliations

1: CNR-Institute of Neurobiology and Molecular Medicine, Via Fosso del Cavaliere100, 00133 Rome, Italy. emanuela.signori@cnr.it

Articles by these authors

The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. J Carcinog (2011) 2.30

Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumors. Clin Cancer Res (2004) 1.55

Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression. Cancer Epidemiol Biomarkers Prev (2009) 1.43

Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. J Biol Chem (2006) 1.34

Unrip is a component of SMN complexes active in snRNP assembly. FEBS Lett (2005) 1.28

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma. Cancer Res (2006) 1.22

Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome. Epigenetics (2011) 1.20

High throughput production of mouse monoclonal antibodies using antigen microarrays. Proteomics (2005) 1.16

Structural analysis of protein inclusion bodies by Fourier transform infrared microspectroscopy. Biochim Biophys Acta (2006) 1.14

Frequent epigenetics inactivation of KEAP1 gene in non-small cell lung cancer. Epigenetics (2011) 1.12

Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation. Proc Natl Acad Sci U S A (2002) 1.12

DNA vaccines: developing new strategies against cancer. J Biomed Biotechnol (2010) 1.12

Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches. Cancer Res (2007) 1.10

Mutations of the D310 mitochondrial mononucleotide repeat in primary tumors and cytological specimens. Cancer Lett (2003) 1.04

A combined analytical approach reveals novel EXT1/2 gene mutations in a large cohort of Italian multiple osteochondromas patients. Genes Chromosomes Cancer (2007) 1.01

High RAD51 mRNA expression characterize estrogen receptor-positive/progesteron receptor-negative breast cancer and is associated with patient's outcome. Int J Cancer (2010) 1.01

Electroporation of skeletal muscle induces danger signal release and antigen-presenting cell recruitment independently of DNA vaccine administration. Expert Opin Biol Ther (2008) 1.00

The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation. EMBO Mol Med (2013) 0.99

Aberrant Keap1 methylation in breast cancer and association with clinicopathological features. Epigenetics (2012) 0.97

Mouse monoclonal antibodies in biological research: strategies for high-throughput production. Biotechnol Lett (2008) 0.96

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma. Cell Cycle (2013) 0.96

Regulatory role of BMP2 and BMP7 in spermatogonia and Sertoli cell proliferation in the immature mouse. Eur J Endocrinol (2004) 0.94

Genomic instability and increased expression of BUB1B and MAD2L1 genes in ductal breast carcinoma. Cancer Lett (2007) 0.93

The RELN locus in Alzheimer's disease. J Alzheimers Dis (2008) 0.91

Simple and effective determination of apolipoprotein E genotypes by positive/negative polymerase chain reaction products. Diagn Mol Pathol (2006) 0.90

FT-IR study of heterologous protein expression in recombinant Escherichia coli strains. Biochim Biophys Acta (2003) 0.88

A new site-specific monoPEGylated filgrastim derivative prepared by enzymatic conjugation: Production and physicochemical characterization. J Control Release (2012) 0.87

HIC1 promoter methylation and 17p13.3 allelic loss in invasive ductal carcinoma of the breast. Cancer Lett (2005) 0.87

Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients. Mol Cancer (2014) 0.86

Biophysical characterization of Met-G-CSF: effects of different site-specific mono-pegylations on protein stability and aggregation. PLoS One (2012) 0.85

High specificity of quantitative methylation-specific PCR analysis for MGMT promoter hypermethylation detection in gliomas. J Biomed Biotechnol (2009) 0.84

Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor. FEBS J (2009) 0.84

Differential modulation of Ku70/80 DNA-binding activity in a patient with multiple basal cell carcinomas. J Invest Dermatol (2003) 0.83

Efficient bacterial expression of fusion proteins and their selective processing by a recombinant Kex-1 protease. Protein Expr Purif (2008) 0.83

Aberrant promoter methylation of beta-1,4 galactosyltransferase 1 as potential cancer-specific biomarker of colorectal tumors. Genes Chromosomes Cancer (2012) 0.83

Relevance of interleukin-1 receptor antagonist intron-2 polymorphism in ischemic stroke. Cerebrovasc Dis (2003) 0.83

Immune response and protection by DNA vaccines expressing antigen 85B of Mycobacterium tuberculosis. FEMS Microbiol Lett (2006) 0.82

Electroporation in DNA vaccination protocols against cancer. Curr Drug Metab (2013) 0.82

DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor. World J Gastroenterol (2005) 0.81

Comparison between real-time quantitative PCR detection of HER2 mRNA copy number in peripheral blood and ELISA of serum HER2 protein for determining HER2 status in breast cancer patients. Cell Oncol (2009) 0.81

Association analysis of GRIN2B, encoding N-methyl-D-aspartate receptor 2B subunit, and Alzheimer's disease. Dement Geriatr Cogn Disord (2008) 0.81

Strategies for improving DNA vaccine performance. Methods Mol Biol (2014) 0.81

Epitope-driven DNA vaccine design employing immunoinformatics against B-cell lymphoma: a biotech's challenge. Biotechnol Adv (2011) 0.80

Molecular dissection of the VHL gene in solitary capillary hemangioblastoma of the central nervous system. J Neuropathol Exp Neurol (2014) 0.79

Adjuvants in vaccines and for immunisation: current trends. Expert Opin Biol Ther (2007) 0.79

Feasibilty of in utero DNA vaccination following naked gene transfer into pig fetal muscle: transgene expression, immunity and safety. Vaccine (2005) 0.79

Evaluation of antigen specific recognition and cell mediated cytotoxicity by a modified lysispot assay in a rat colon carcinoma model. J Exp Clin Cancer Res (2012) 0.79

Design and pre-clinical development of epitope-based DNA vaccines against B-cell lymphoma. Curr Gene Ther (2011) 0.78

Anti-tumor immunity induced by CDR3-based DNA vaccination in a murine B-cell lymphoma model. Biochem Biophys Res Commun (2008) 0.78

Increased nerve growth factor serum levels in top athletes. Clin J Sport Med (2013) 0.78

Characterization of Escherichia coli uridine phosphorylase by single-site mutagenesis. J Biochem (2004) 0.78

The pathological cross talk between apolipoprotein E and amyloid-beta peptide in Alzheimer's disease: emerging gene-based therapeutic approaches. J Alzheimers Dis (2010) 0.78

Comparison of circadian characteristics for cytotoxic lymphocyte subsets in non-small cell lung cancer patients versus controls. Clin Exp Med (2011) 0.78

Tailored PEG for rh-G-CSF analogue site-specific conjugation. Bioconjug Chem (2009) 0.78

Gene expression of somatostatin receptor subtypes SSTR2a, SSTR3 and SSTR5 in peripheral blood of neuroendocrine lung cancer affected patients. Cell Oncol (Dordr) (2011) 0.78

Self-assembling nanocomposites for protein delivery: supramolecular interactions between PEG-cholane and rh-G-CSF. J Control Release (2012) 0.78

Asthma, allergy and the Olympics: a 12-year survey in elite athletes. Curr Opin Allergy Clin Immunol (2015) 0.77

ApoE gene delivery inhibits severe hypercholesterolemia in newborn ApoE-KO mice. Biochem Biophys Res Commun (2007) 0.77

Mycobacterium smegmatis expressing a chimeric protein MPT64-proteolipid protein (PLP) 139-151 reorganizes the PLP-specific T cell repertoire favoring a CD8-mediated response and induces a relapsing experimental autoimmune encephalomyelitis. J Immunol (2009) 0.77

Antiphase signalling in the neuroendocrine-immune system in healthy humans. Biomed Pharmacother (2011) 0.76

Strategies for effective naked-DNA vaccination against infectious diseases. Recent Pat Antiinfect Drug Discov (2008) 0.76

Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival in a mouse model of lymphoma. J Biomed Biotechnol (2010) 0.76

Recent advances in design of immunogenic and effective naked DNA vaccines against cancer. Recent Pat Anticancer Drug Discov (2014) 0.76

Cord blood CD133 cells define an OV6-positive population that can be differentiated in vitro into engraftable bipotent hepatic progenitors. Stem Cells Dev (2011) 0.76