Modulation of steroid hormone receptor activity.

Epigenetic perspective on the developmental effects of bisphenol A. Brain Behav Immun (2011) 1.43

Regulation of specific target genes and biological responses by estrogen receptor subtype agonists. Curr Opin Pharmacol (2010) 1.12

Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation. Endocr Rev (2012) 1.11

Central regulation of blood pressure by the mineralocorticoid receptor. Mol Cell Endocrinol (2011) 0.92

Targeting the glucocorticoid receptor in breast and prostate cancers. Sci Transl Med (2015) 0.91

Type I IFN receptor controls activated TYK2 in the nucleus: implications for EAE therapy. J Neuroimmunol (2012) 0.90

Multiple roles of COUP-TFII in cancer initiation and progression. J Mol Endocrinol (2012) 0.89

IFN signaling: how a non-canonical model led to the development of IFN mimetics. Front Immunol (2013) 0.87

Steroid-like signalling by interferons: making sense of specific gene activation by cytokines. Biochem J (2012) 0.87

Glucocorticoid receptors, epidermal homeostasis and hair follicle differentiation. Dermatoendocrinol (2011) 0.87

ER and PR signaling nodes during mammary gland development. Breast Cancer Res (2012) 0.86

IQGAP1 binds to estrogen receptor-α and modulates its function. J Biol Chem (2014) 0.86

The multifaceted mineralocorticoid receptor. Compr Physiol (2014) 0.85

Progesterone and related compounds in hepatocellular carcinoma: basic and clinical aspects. Biomed Res Int (2013) 0.85

Keratinocyte-targeted overexpression of the glucocorticoid receptor delays cutaneous wound healing. PLoS One (2012) 0.83

Genome-wide coexpression of steroid receptors in the mouse brain: Identifying signaling pathways and functionally coordinated regions. Proc Natl Acad Sci U S A (2016) 0.83

The role of a non-canonical JAK-STAT pathway in IFN therapy of poxvirus infection and multiple sclerosis: An example of Occam's Broom? JAKSTAT (2013) 0.81

Short peptide type I interferon mimetics: therapeutics for experimental allergic encephalomyelitis, melanoma, and viral infections. J Interferon Cytokine Res (2014) 0.81

Mineralocorticoid receptors in the brain and cardiovascular regulation: minority rule? Trends Endocrinol Metab (2011) 0.79

Steroid receptor coactivator 2 modulates steroid-dependent male sexual behavior and neuroplasticity in Japanese quail (Coturnix japonica). J Neurochem (2011) 0.78

Expression of the oestrogen receptor GPER by testicular peritubular cells is linked to sexual maturation and male fertility. Andrology (2014) 0.77

Steroid hormone receptors and prostate cancer: role of structural dynamics in therapeutic targeting. Asian J Androl (2016) 0.77

Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain. Nat Rev Neurosci (2017) 0.76

Estradiol Preferentially Induces Progestin Receptor-A (PR-A) Over PR-B in Cells Expressing Nuclear Receptor Coactivators in the Female Mouse Hypothalamus(1,2,3). eNeuro (2015) 0.76

Type I interferon mimetics bypass vaccinia virus decoy receptor virulence factor for protection of mice against lethal infection. Clin Vaccine Immunol (2014) 0.76

The cellular membrane as a mediator for small molecule interaction with membrane proteins. Biochim Biophys Acta (2016) 0.75

Transmembrane helices in "classical" nuclear reproductive steroid receptors: a perspective. Nucl Recept Signal (2015) 0.75

Combinatorial control of gene expression by nuclear receptors and coregulators. Cell (2002) 8.01

Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45

SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell (2002) 4.31

Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev (2004) 3.74

Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer (2009) 3.33

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17

The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09

Analysis of the human endogenous coregulator complexome. Cell (2011) 2.97

Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95

SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell (2007) 2.69

Nuclear receptor coregulators and human disease. Endocr Rev (2007) 2.65

An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell (2007) 2.57

The expanding cosmos of nuclear receptor coactivators. Cell (2006) 2.57

Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science (2002) 2.53

Retracted Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell (2009) 2.48

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45

Transoral robotic surgery for advanced oropharyngeal carcinoma. Arch Otolaryngol Head Neck Surg (2010) 2.31

Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol Cell (2007) 2.31

Transoral robotic surgery: radical tonsillectomy. Arch Otolaryngol Head Neck Surg (2007) 2.28

SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18

AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res (2004) 2.07

Minireview: nuclear receptor coactivators--an update. Endocrinology (2002) 2.04

Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol (2007) 2.02

Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol (2006) 1.94

Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab (2011) 1.89

Reproductive functions of progesterone receptors. Recent Prog Horm Res (2002) 1.82

Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol Cell (2005) 1.82

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A (2008) 1.80

CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing. Mol Cell Biol (2004) 1.77

The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol (2008) 1.75

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol (2005) 1.74

Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73

Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A (2010) 1.72

Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proc Natl Acad Sci U S A (2005) 1.72

Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell (2005) 1.66

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proc Natl Acad Sci U S A (2013) 1.66

Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A (2008) 1.62

A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol (2002) 1.61

Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res (2005) 1.60

Expanding functional diversity of the coactivators. Trends Biochem Sci (2005) 1.57

SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Mol Cell (2006) 1.57

Steroid receptor coactivator (SRC) family: masters of systems biology. J Biol Chem (2010) 1.57

Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet (2013) 1.56

Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol (2012) 1.55

In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy. J Control Release (2004) 1.53

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest (2015) 1.53

The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res (2008) 1.53

Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52

Transoral robotic surgery: supraglottic partial laryngectomy. Ann Otol Rhinol Laryngol (2007) 1.51

Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins. Laryngoscope (2012) 1.49

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49

Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49

Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol (2005) 1.45

Transoral robotic surgery alone for oropharyngeal cancer: an analysis of local control. Arch Otolaryngol Head Neck Surg (2012) 1.44

Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes. Proc Natl Acad Sci U S A (2004) 1.44

Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol (2002) 1.42

Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol (2002) 1.42

A repressive role for prohibitin in estrogen signaling. Mol Endocrinol (2007) 1.40

Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol (2005) 1.36

Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A (2002) 1.35

Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proc Natl Acad Sci U S A (2002) 1.35

Transoral robotic surgery and human papillomavirus status: Oncologic results. Head Neck (2010) 1.33

Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol (2007) 1.32

Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr Rev (2005) 1.32

Multi-modulation of nuclear receptor coactivators through posttranslational modifications. Trends Endocrinol Metab (2008) 1.31

Endoscopic closure of CSF rhinorrhea: 193 cases over 21 years. Otolaryngol Head Neck Surg (2009) 1.30

Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell (2008) 1.29

Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology (2003) 1.28

Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function. Rev Endocr Metab Disord (2002) 1.28

Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell (2008) 1.27

Transoral robotic surgery for oropharyngeal carcinoma and its impact on patient-reported quality of life and function. Head Neck (2011) 1.26

Transoral robotic surgery: does the ends justify the means? Curr Opin Otolaryngol Head Neck Surg (2009) 1.26

Unfolding the action of progesterone receptors. J Biol Chem (2003) 1.26

Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol (2005) 1.25

Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol (2005) 1.25

Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1. Proc Natl Acad Sci U S A (2007) 1.25

SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci (2003) 1.24

Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1. Mol Endocrinol (2011) 1.23

Rush hour at the promoter: how the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcription. J Steroid Biochem Mol Biol (2005) 1.23

Absence of the steroid receptor coactivator-3 induces B-cell lymphoma. EMBO J (2006) 1.22

Nuclear receptor coactivators: master regulators of human health and disease. Annu Rev Med (2013) 1.22

A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol (2005) 1.22

Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy. Mol Cell Endocrinol (2011) 1.22

Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Mol Cell Biol (2003) 1.22

The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism. Mol Endocrinol (2006) 1.21

Inhibition of NK cell activity through TGF-beta 1 by down-regulation of NKG2D in a murine model of head and neck cancer. J Immunol (2005) 1.21

A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med (2012) 1.20

Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology (2005) 1.20

Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol (2006) 1.19

Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A (2004) 1.19

Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription? Mol Endocrinol (2003) 1.19