Published in J Clin Invest on May 17, 2010
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell (2011) 2.10
Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice. Gastroenterology (2013) 1.62
p120-catenin binding masks an endocytic signal conserved in classical cadherins. J Cell Biol (2012) 1.48
Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics. Front Immunol (2013) 1.41
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation. PLoS One (2010) 1.33
Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice. Gastroenterology (2011) 1.28
Epithelial barrier function: at the front line of asthma immunology and allergic airway inflammation. J Allergy Clin Immunol (2014) 1.26
Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling. Subcell Biochem (2012) 1.10
Rab25 as a tumour suppressor in colon carcinogenesis. Br J Cancer (2010) 1.10
p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression. Prog Mol Biol Transl Sci (2013) 1.04
Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis. J Immunol (2011) 1.03
PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity. Circ Res (2012) 1.03
p120-catenin is essential for terminal end bud function and mammary morphogenesis. Development (2012) 0.99
The molecular evolution of the p120-catenin subfamily and its functional associations. PLoS One (2010) 0.98
Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS One (2011) 0.98
p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development (2011) 0.96
PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions. Am J Physiol Cell Physiol (2010) 0.95
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability. J Biol Chem (2013) 0.95
Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression. Tissue Barriers (2013) 0.92
A membrane fusion protein αSNAP is a novel regulator of epithelial apical junctions. PLoS One (2012) 0.91
Polyamines and Gut Mucosal Homeostasis. J Gastrointest Dig Syst (2012) 0.89
E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 protein during restitution. J Biol Chem (2012) 0.88
Epithelial adhesion molecules and the regulation of intestinal homeostasis during neutrophil transepithelial migration. Tissue Barriers (2015) 0.87
Breaking barriers. New insights into airway epithelial barrier function in health and disease. Am J Respir Cell Mol Biol (2014) 0.87
p120-Catenin: a novel regulator of innate immunity and inflammation. Crit Rev Immunol (2012) 0.86
Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles. Physiol Genomics (2010) 0.85
p120 modulates LPS-induced NF-κB activation partially through RhoA in bronchial epithelial cells. Biomed Res Int (2014) 0.84
Microbiome, inflammation, and cancer. Cancer J (2014) 0.82
Neutrophil-Epithelial Interactions: A Double-Edged Sword. Am J Pathol (2016) 0.82
Roles of the cellular prion protein in the regulation of cell-cell junctions and barrier function. Tissue Barriers (2013) 0.82
Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res (2011) 0.82
p120-catenin expressed in alveolar type II cells is essential for the regulation of lung innate immune response. Am J Pathol (2015) 0.81
p120catenin alteration in cancer and its role in tumour invasion. Philos Trans R Soc Lond B Biol Sci (2013) 0.81
p120-catenin controls contractility along the vertical axis of epithelial lateral membranes. J Cell Sci (2015) 0.81
p120 catenin is required for the stress response in Drosophila. PLoS One (2013) 0.80
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol (2014) 0.80
Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis. Sci Rep (2016) 0.79
Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair. Gastroenterology (2016) 0.79
The intestinal epithelial barrier: a therapeutic target? Nat Rev Gastroenterol Hepatol (2016) 0.78
The POZ-ZF transcription factor Kaiso (ZBTB33) induces inflammation and progenitor cell differentiation in the murine intestine. PLoS One (2013) 0.78
Phosphorylation and isoform use in p120-catenin during development and tumorigenesis. Biochim Biophys Acta (2015) 0.77
Guilt by association: what p120-catenin has to hide. J Cell Biol (2012) 0.77
Pathobiology of neutrophil-epithelial interactions. Immunol Rev (2016) 0.77
Leukocyte-epithelial interactions and mucosal homeostasis. Toxicol Pathol (2013) 0.76
E-cadherin Is Important for the Maintenance of Intestinal Epithelial Homeostasis Under Basal and Inflammatory Conditions. Dig Dis Sci (2015) 0.76
The Misregulation of Cell Adhesion Components during Tumorigenesis: Overview and Commentary. J Oncol (2010) 0.76
A central role for cadherin signaling in cancer. Exp Cell Res (2017) 0.75
Arp2/3 complex function in the epidermis. Tissue Barriers (2014) 0.75
Rho GEFs in endothelial junctions: Effector selectivity and signaling integration determine junctional response. Tissue Barriers (2013) 0.75
The mucosal barrier at a glance. J Cell Sci (2017) 0.75
p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun (2016) 0.75
Epithelial-mesenchymal transition and nuclear β-catenin induced by conditional intestinal disruption of Cdh1 with Apc is E-cadherin EC1 domain dependent. Oncotarget (2016) 0.75
Trpm7 Protein Contributes to Intercellular Junction Formation in Mouse Urothelium. J Biol Chem (2015) 0.75
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer. PLoS One (2015) 0.75
Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease. Dis Model Mech (2015) 0.75
cAMP-dependent activation of protein kinase A attenuates respiratory syncytial virus-induced human airway epithelial barrier disruption. PLoS One (2017) 0.75
βIII spectrin is necessary for formation of the constricted neck of dendritic spines and regulation of synaptic activity in neurons. J Neurosci (2017) 0.75
Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility. J Cell Biol (2017) 0.75
Unravelling the pathogenesis of inflammatory bowel disease. Nature (2007) 18.52
Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology (2004) 14.78
THE DEVELOPMENT OF THE BACTERIAL FLORA IN THE GASTROINTESTINAL TRACT OF MICE. J Exp Med (1965) 12.70
Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology (1998) 9.58
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem (2002) 7.74
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell (1996) 7.46
Morphogenetic roles of classic cadherins. Curr Opin Cell Biol (1995) 6.95
Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc Natl Acad Sci U S A (1995) 5.54
The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression. Cell (1991) 5.27
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest (2008) 5.26
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J (1995) 4.55
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell (2006) 4.24
A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction. J Clin Invest (1991) 3.67
The uvomorulin-anchorage protein alpha catenin is a vinculin homologue. Proc Natl Acad Sci U S A (1991) 3.62
p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol (2000) 3.60
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells. J Cell Biol (2003) 3.39
E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene (1996) 3.35
Inhibition of RhoA by p120 catenin. Nat Cell Biol (2000) 3.33
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell (2004) 3.33
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science (1995) 3.16
The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor. Mol Cell Biol (1999) 3.02
In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J Cell Biol (1995) 2.95
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. Genes Dev (2001) 2.91
Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Dev Cell (2005) 2.86
The c-jun kinase/stress-activated pathway: regulation, function and role in human disease. Biochim Biophys Acta (2007) 2.83
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene (1999) 2.66
JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med (2007) 2.63
Mouse models of inflammatory bowel disease. Adv Drug Deliv Rev (2007) 2.42
p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion. J Cell Sci (2001) 2.40
Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins. Am J Pathol (2001) 2.31
p120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins. Neuron (2006) 2.10
The primary defect in experimental ileitis originates from a nonhematopoietic source. J Exp Med (2006) 1.96
Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention. Semin Perinatol (2008) 1.90
Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. Genes Dev (1996) 1.82
The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation. Eur J Cancer (2000) 1.82
Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Dev Cell (2006) 1.77
Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. J Cell Sci (1996) 1.74
Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin. Nat Cell Biol (2004) 1.73
The morphogenetic role of cadherin cell adhesion molecules in human cancer: a thematic review. Cancer Invest (1998) 1.58
Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer. Semin Cell Dev Biol (2004) 1.55
Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors. Inflamm Bowel Dis (2009) 1.53
The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysin. Exp Cell Res (2005) 1.53
Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms. Am J Physiol Cell Physiol (2002) 1.50
Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice. Gastroenterology (2002) 1.45
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer. Proc Natl Acad Sci U S A (2008) 1.40
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines. Cancer Res (2008) 1.36
Dancing in and out of the nucleus: p120(ctn) and the transcription factor Kaiso. Biochim Biophys Acta (2006) 1.36
Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancer. Virchows Arch A Pathol Anat Histopathol (1992) 1.35
Ezrin...a metastatic detERMinant? Cancer Cell (2004) 1.33
Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine. Ann Med (2007) 1.29
Developmental regulation of villin gene expression in the epithelial cell lineages of mouse digestive and urogenital tracts. Development (1992) 1.21
Expression of catenins and E-cadherin during epithelial restitution in inflammatory bowel disease. J Pathol (1998) 1.19
Mechanism of extracellular domain-deleted dominant negative cadherins. J Cell Sci (1999) 1.17
The development of animal models for the study of necrotizing enterocolitis. Dis Model Mech (2008) 1.10
The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways. Development (2009) 1.09
Cyclooxygenase-2 and its role in colorectal cancer development. Virchows Arch (2004) 1.07
Colonic expression of leukotriene-pathway enzymes in inflammatory bowel diseases. Inflamm Bowel Dis (2007) 1.03
Cadherin function in junctional complex rearrangement and posttranslational control of cadherin expression. Am J Physiol (1999) 1.01
Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migration. J Immunol (2002) 0.95
Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils. Biochim Biophys Acta (2007) 0.93
Dietary fatty acids modulate chronic colitis, colitis-associated colon neoplasia and COX-2 expression in IL-10 knockout mice. Nutrition (2006) 0.89
Regulation of stromal cell cyclooxygenase-2 in the ApcMin/+ mouse model of intestinal tumorigenesis. Carcinogenesis (2005) 0.88
PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway. Exp Cell Res (2008) 0.86
Colonic neutrophils in inflammatory bowel disease: double-edged swords of the innate immune system with protective and destructive capacity. Gastroenterology (2007) 0.84
Disassembly of endothelial and epithelial junctions during leukocyte transmigration. Front Biosci (2008) 0.83
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science (2004) 10.23
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem (2002) 7.74
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol (2006) 5.49
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell (2006) 4.24
Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology (2003) 4.10
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology (2009) 4.08
A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology (2006) 3.96
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell (2012) 3.91
EGF receptor ligands. Exp Cell Res (2003) 3.60
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development (2005) 3.57
EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell (2012) 3.19
Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J Clin Invest (2005) 3.02
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol (2007) 2.70
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci U S A (2002) 2.65
Histopathologic diagnosis of chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report. Biol Blood Marrow Transplant (2006) 2.63
Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development (2004) 2.62
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. Mol Cell (2003) 2.47
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells. Development (2011) 2.45
Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest (2002) 2.28
Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell (2010) 2.20
Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. J Clin Invest (2011) 2.16
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Res (2006) 2.14
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell (2011) 2.10
Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin. J Invest Dermatol (2009) 2.06
Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and function. J Am Soc Nephrol (2008) 2.04
The p120(ctn)-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides. Nucleic Acids Res (2002) 2.02
Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells. Nat Cell Biol (2009) 2.00
Amphiregulin exosomes increase cancer cell invasion. Curr Biol (2011) 1.93
Potentiation of oxyntic atrophy-induced gastric metaplasia in amphiregulin-deficient mice. Gastroenterology (2007) 1.87
Proteome analysis of human colon cancer by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics (2004) 1.82
Altered expression of the catenin p120 in human cancer: implications for tumor progression. Differentiation (2002) 1.80
Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Dev Cell (2006) 1.77
Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology (2009) 1.76
ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis. Biochem Biophys Res Commun (2003) 1.70
Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. Cancer Res (2010) 1.69
Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis. Mol Cancer Ther (2010) 1.67
Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions. Curr Biol (2012) 1.67
Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells. Gut (2011) 1.67
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clin Cancer Res (2008) 1.66
Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps. Clin Cancer Res (2005) 1.59
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Mol Cell Proteomics (2012) 1.55
Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth. Clin Cancer Res (2011) 1.55
Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology (2010) 1.53
The enterocyte microvillus is a vesicle-generating organelle. J Cell Biol (2009) 1.51
TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway. Gastroenterology (2009) 1.50
Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology (2007) 1.45
Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Cancer Res (2010) 1.45
Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality. J Cell Biol (2006) 1.44
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. Clin Cancer Res (2008) 1.44
A novel interaction between kinesin and p120 modulates p120 localization and function. J Biol Chem (2003) 1.43
PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. Proc Natl Acad Sci U S A (2004) 1.42
Transactivation of the epidermal growth factor receptor in colonic epithelial cells by carbachol requires extracellular release of transforming growth factor-alpha. J Biol Chem (2002) 1.42
Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin. Gastroenterology (2011) 1.40
Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J Clin Invest (2004) 1.40
Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model. PLoS One (2011) 1.38
Randomized phase II trial of the clinical and biological effects of two dose levels of gefitinib in patients with recurrent colorectal adenocarcinoma. J Clin Oncol (2005) 1.38
Protecting your tail: regulation of cadherin degradation by p120-catenin. Curr Opin Cell Biol (2004) 1.37
Volume of preclinical xenograft tumors is more accurately assessed by ultrasound imaging than manual caliper measurements. J Ultrasound Med (2010) 1.35
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. J Clin Invest (2010) 1.35
Helicobacter pylori strain-selective induction of matrix metalloproteinase-7 in vitro and within gastric mucosa. Gastroenterology (2003) 1.34
The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells. Mol Cancer Ther (2012) 1.33
Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev Biol (2007) 1.32
Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol (2006) 1.32
Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells. Proc Natl Acad Sci U S A (2004) 1.30
Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Gastroenterology (2009) 1.28
Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology (2003) 1.28
Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk. Physiol Genomics (2007) 1.27
The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment. Blood (2008) 1.27
EGFR signaling to p120-catenin through phosphorylation at Y228. J Cell Sci (2004) 1.25
Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol (2011) 1.23
Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech Dev (2009) 1.23
Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. J Cell Biol (2010) 1.22
Hedgehog-responsive mesenchymal clusters direct patterning and emergence of intestinal villi. Proc Natl Acad Sci U S A (2012) 1.20
Lipopolysaccharide-induced expression of multiple alternatively spliced MEFV transcripts in human synovial fibroblasts: a prominent splice isoform lacks the C-terminal domain that is highly mutated in familial Mediterranean fever. Arthritis Rheum (2004) 1.20
Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res (2008) 1.20
Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci. Mol Biol Cell (2004) 1.20
Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. Cancer Res (2007) 1.19
Adhesion-associated and PKC-modulated changes in serine/threonine phosphorylation of p120-catenin. Biochemistry (2003) 1.19
Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane. J Biol Chem (2010) 1.18
Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development (2011) 1.18
Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis. Mol Cell Proteomics (2008) 1.18
Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium. J Cell Physiol (2007) 1.18
Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria. Gastroenterology (2010) 1.17
Detection of Escherichia coli serogroups O26 and O113 by PCR amplification of the wzx and wzy genes. Appl Environ Microbiol (2004) 1.17
Regulation of p120-catenin nucleocytoplasmic shuttling activity. J Cell Sci (2003) 1.17
High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis. Infect Immun (2013) 1.16
p120-Catenin is required for mouse vascular development. Circ Res (2010) 1.16