Pharmacokinetic/pharmacodynamic analysis of adjuvant pegylated interferon α-2b in patients with resected high-risk melanoma.

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Published in Cancer Chemother Pharmacol on May 28, 2010

Authors

A I Daud1, C Xu, W-J Hwu, P Urbas, S Andrews, N E Papadopoulos, L C Floren, A Yver, R C Deconti, V K Sondak

Author Affiliations

1: Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA, USA. adaud@medicine.ucsf.edu

Associated clinical trials:

High-Dose PEG-Intron Pharmacokinetic Study in Patients With Melanoma (Study P04831 AM2) | NCT00457418

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CT of recurrent retroperitoneal sarcomas. AJR Am J Roentgenol (2000) 1.01