Neil D Perkins

Author PubWeight™ 61.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 P300 transcriptional repression is mediated by SUMO modification. Mol Cell 2003 3.67
2 Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol Cell 2004 3.45
3 SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem 2005 2.59
4 The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor. EMBO J 2005 2.12
5 p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor. Mol Cell 2003 1.92
6 p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1. Mol Cell Biol 2003 1.75
7 SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes. Mol Cell 2006 1.73
8 Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit. EMBO J 2006 1.73
9 Transcriptional profiling of the LPS induced NF-kappaB response in macrophages. BMC Immunol 2007 1.71
10 Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor. EMBO J 2005 1.69
11 DNA-dependent acetylation of p53 by the transcription coactivator p300. J Biol Chem 2002 1.59
12 Retracted A cell cycle regulatory network controlling NF-kappaB subunit activity and function. EMBO J 2007 1.58
13 Retracted The Skp2 promoter integrates signaling through the NF-kappaB, p53, and Akt/GSK3beta pathways to regulate autophagy and apoptosis. Mol Cell 2010 1.34
14 Regulation of cyclin D1 RNA stability by SNIP1. Cancer Res 2008 1.33
15 Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism. J Biol Chem 2005 1.33
16 The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner. BMC Mol Biol 2004 1.31
17 p53 and NF-kappaB crosstalk: IKKalpha tips the balance. Mol Cell 2007 1.30
18 Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases. J Biol Chem 2005 1.28
19 Regulation of cyclin D1 gene expression. Biochem Soc Trans 2010 1.20
20 Regulation of NF-kappaB function. Biochem Soc Symp 2006 1.18
21 Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation. Cancer Res 2006 1.15
22 The ETS domain transcription factor Elk-1 contains a novel class of repression domain. Mol Cell Biol 2002 1.12
23 Not just a CDK inhibitor: regulation of transcription by p21(WAF1/CIP1/SDI1). Cell Cycle 2002 1.10
24 Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect. Trends Biochem Sci 2012 1.09
25 IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis. Biochim Biophys Acta 2007 1.03
26 The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration. Mol Biol Cell 2011 1.02
27 Regulation of the RelA (p65) transactivation domain. Biochem Soc Trans 2008 1.02
28 A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism involving protein kinase C-theta-mediated up-regulation of the amino-terminal transactivation domain of p300. J Immunol 2008 1.02
29 Regulation of RelA (p65) function by the large subunit of replication factor C. Mol Cell Biol 2003 1.02
30 Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. BMC Cancer 2006 1.01
31 The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression. Oncogene 2004 0.98
32 Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21. Mol Cell 2013 0.97
33 Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation. Biochem J 2010 0.96
34 p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB. Cancer Res 2011 0.95
35 Retracted Regulation of activity and function of the p52 NF-κB subunit following DNA damage. Cell Cycle 2010 0.92
36 NF-κB is a critical mediator of BRCA1-induced chemoresistance. Oncogene 2013 0.88
37 The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro. BMC Mol Biol 2003 0.87
38 Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. Hepatology 2013 0.86
39 Induction of transcription by p21Waf1/Cip1/Sdi1: role of NFkappaB and effect of non-steroidal anti-inflammatory drugs. Cell Cycle 2004 0.85
40 Induction of transcription through the p300 CRD1 motif by p21WAF1/CIP1 is core promoter specific and cyclin dependent kinase independent. Cell Cycle 2002 0.84
41 Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins. J Proteome Res 2014 0.84
42 The large subunit of replication factor C interacts with the histone deacetylase, HDAC1. J Biol Chem 2002 0.84
43 p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding. Cell Cycle 2005 0.82
44 ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases. Cell Cycle 2005 0.82
45 A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc. Biochem J 2002 0.81
46 Reprogramming RelA. Cell Cycle 2004 0.81
47 Retracted Phosphorylation of the p52 NF-κB subunit. Cell Cycle 2010 0.81
48 NFκB regulates expression of Polo-like kinase 4. Cell Cycle 2013 0.79
49 Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence. Onco Targets Ther 2013 0.77
50 Correction: A238L Inhibits NF-ATc2, NF-κB, and c-Jun Activation through a Novel Mechanism Involving Protein Kinase C-θ-Mediated Up-Regulation of the Amino-Terminal Transactivation Domain of p300. J Immunol 2015 0.75