Published in Radiat Res on June 01, 2010
Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol (2013) 1.49
Radiation countermeasure agents: an update (2011-2014). Expert Opin Ther Pat (2014) 1.02
Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures. J Radiat Res (2013) 0.98
Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. Int J Radiat Oncol Biol Phys (2010) 0.96
Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res (2010) 0.95
γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death. J Pharmacol Exp Ther (2011) 0.94
Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice. J Radiat Res (2012) 0.92
Medical Countermeasures for Radiation Exposure and Related Injuries: Characterization of Medicines, FDA-Approval Status and Inclusion into the Strategic National Stockpile. Health Phys (2015) 0.91
Mitigation of Lethal Radiation Syndrome in Mice by Intramuscular Injection of 3D Cultured Adherent Human Placental Stromal Cells. PLoS One (2013) 0.88
Pharmacological potential of tocotrienols: a review. Nutr Metab (Lond) (2014) 0.88
New approaches to radiation protection. Front Oncol (2015) 0.85
Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice. PLoS One (2015) 0.85
Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure. PLoS One (2014) 0.82
Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability. Drug Dev Res (2013) 0.80
High Levels of Dietary Supplement Vitamins A, C and E are Absorbed in the Small Intestine and Protect Nutrient Transport Against Chronic Gamma Irradiation. Radiat Res (2015) 0.79
Vitamin E Analogs as Radiation Response Modifiers. Evid Based Complement Alternat Med (2015) 0.78
Synergistic radioprotection by gamma-tocotrienol and pentoxifylline: role of cAMP signaling. ISRN Radiol (2013) 0.77
γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. Int J Mol Sci (2016) 0.76
Protection against Radiotherapy-Induced Toxicity. Antioxidants (Basel) (2016) 0.75
Development of Orally Administered γ-Tocotrienol (GT3) Nanoemulsion for Radioprotection. Int J Mol Sci (2016) 0.75
Gamma-Tocotrienol Modulates Radiation-Induced MicroRNA Expression in Mouse Spleen. Radiat Res (2016) 0.75
Appraisal of biochemical classes of radioprotectors: evidence, current status and guidelines for future development. 3 Biotech (2017) 0.75
Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different Radiosensitivity. Radiat Res (2017) 0.75
Pharmacological Modulation of Radiation Damage. Does It Exist a Chance for Other Substances than Hematopoietic Growth Factors and Cytokines? Int J Mol Sci (2017) 0.75
Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer (2004) 3.83
Animal models for medical countermeasures to radiation exposure. Radiat Res (2010) 2.83
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
Comparison of mortality rates in statin users versus nonstatin users in a United States veteran population. Am J Cardiol (2006) 2.19
Literature review and global consensus on management of acute radiation syndrome affecting nonhematopoietic organ systems. Disaster Med Public Health Prep (2011) 1.93
The radiotherapeutic injury--a complex 'wound'. Radiother Oncol (2002) 1.82
Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin. Circ Res (2008) 1.64
Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nat Med (2012) 1.58
Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol (2013) 1.49
Normal tissue effects: reporting and analysis. Semin Radiat Oncol (2003) 1.44
Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol (2007) 1.42
Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis. Am J Pathol (2002) 1.39
The relationship between alcohol use and risk-taking sexual behaviors in a large behavioral study. Prev Med (2004) 1.37
gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. Radiat Res (2009) 1.32
Impact of renal transplantation on survival in end-stage renal disease patients with elevated body mass index. Kidney Int (2003) 1.32
Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo. J Appl Physiol (1985) (2008) 1.30
Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. Int J Radiat Biol (2009) 1.29
Protection from adverse myocardial remodeling secondary to chronic volume overload in mast cell deficient rats. J Mol Cell Cardiol (2008) 1.27
Interlaboratory comparison of the dicentric chromosome assay for radiation biodosimetry in mass casualty events. Radiat Res (2008) 1.23
Decreasing the adverse effects of cancer therapy: National Cancer Institute guidance for the clinical development of radiation injury mitigators. Clin Cancer Res (2010) 1.22
Prostate-specific antigen versus prostate-specific antigen density as predictor of tumor volume, margin status, pathologic stage, and biochemical recurrence of prostate cancer. Urology (2005) 1.13
Nonfatal Suicidal Behaviors in U.S. Army Administrative Records, 2004-2009: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Psychiatry (2015) 1.11
Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition. Blood Coagul Fibrinolysis (2006) 1.11
Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis (2008) 1.11
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol. Int J Radiat Oncol Biol Phys (2008) 1.10
First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation. Disaster Med Public Health Prep (2011) 1.10
Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells. Mol Cancer Ther (2006) 1.09
Defining pelvic-radiation disease for the survivorship era. Lancet Oncol (2010) 1.09
Hyperhomocysteinemia leads to pathological ventricular hypertrophy in normotensive rats. Am J Physiol Heart Circ Physiol (2003) 1.09
Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation. Blood Coagul Fibrinolysis (2003) 1.07
Development of a combined radiation and burn injury model. J Burn Care Res (2011) 1.07
Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Cancer Res (2005) 1.06
Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome. Hernia (2006) 1.05
Alpha-tocopherol succinate protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor. Int J Radiat Biol (2010) 1.05
Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol (2009) 1.04
The somatostatin analog SOM230 (pasireotide) ameliorates injury of the intestinal mucosa and increases survival after total-body irradiation by inhibiting exocrine pancreatic secretion. Radiat Res (2009) 1.02
Pharmacotherapy and the risk for community-acquired pneumonia. BMC Geriatr (2010) 1.01
"Pelvic radiation disease": new understanding and new solutions for a new disease in the era of cancer survivorship. Scand J Gastroenterol (2010) 1.00
Gastrointestinal mucositis. Semin Oncol Nurs (2004) 1.00
Diet synergistically affects helicobacter pylori-induced gastric carcinogenesis in nonhuman primates. Gastroenterology (2009) 1.00
Comparison of 10 hemostatic dressings in a groin transection model in swine. J Trauma (2009) 0.99
Uses of proton pump inhibitors and hypomagnesemia. Pharmacoepidemiol Drug Saf (2012) 0.99
Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int J Radiat Oncol Biol Phys (2007) 0.99
Lactate stimulates vasculogenic stem cells via the thioredoxin system and engages an autocrine activation loop involving hypoxia-inducible factor 1. Mol Cell Biol (2008) 0.98
Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. Cytokine (2013) 0.98
Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol. Radiat Res (2011) 0.98
Influence of sublethal total-body irradiation on immune cell populations in the intestinal mucosa. Radiat Res (2010) 0.97
Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor. Int Immunopharmacol (2012) 0.97
Nutritional approaches to radioprotection: vitamin E. Mil Med (2002) 0.96
Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. Int J Radiat Oncol Biol Phys (2010) 0.96
Induction of cytokines by radioprotective tocopherol analogs. Exp Mol Pathol (2006) 0.96
PARP1 is required for chromosomal translocations. Blood (2013) 0.96
Hematological targets of radiation damage. Curr Drug Targets (2010) 0.95
Preferential radiation sensitization of prostate cancer in nude mice by nutraceutical antioxidant gamma-tocotrienol. Life Sci (2006) 0.95
Correlations between serum monocyte chemotactic protein-1 levels, clinical prognostic factors, and HER-2/neu vaccine-related immunity in breast cancer patients. Clin Cancer Res (2006) 0.95
Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res (2010) 0.95
IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS One (2011) 0.95
A novel technique for image-guided local heart irradiation in the rat. Technol Cancer Res Treat (2013) 0.95
γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death. J Pharmacol Exp Ther (2011) 0.94
Tocopherol succinate: a promising radiation countermeasure. Int Immunopharmacol (2009) 0.94
HYOU1/Orp150 expression in breast cancer. Med Sci Monit (2007) 0.93
Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis. Nat Commun (2011) 0.93
Cardiac inflammation after local irradiation is influenced by the kallikrein-kinin system. Cancer Res (2012) 0.93
Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms. Radiat Res (2009) 0.92
Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice. J Radiat Res (2012) 0.92
Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease. J Inherit Metab Dis (2010) 0.92
Influence of mast cells on outcome after heterotopic cardiac transplantation in rats. Transpl Int (2007) 0.92
Local administration of interleukin-11 ameliorates intestinal radiation injury in rats. Cancer Res (2007) 0.92
Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model. PLoS One (2013) 0.91
Up-regulation and activation of proteinase-activated receptor 2 in early and delayed radiation injury in the rat intestine: influence of biological activators of proteinase-activated receptor 2. Radiat Res (2003) 0.91
Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats. Am J Physiol Heart Circ Physiol (2002) 0.91
Determination of sample sizes for demonstrating efficacy of radiation countermeasures. Biometrics (2009) 0.91
Mechanisms underlying the radioprotective properties of γ-tocotrienol: comparative gene expression profiling in tocol-treated endothelial cells. Genes Nutr (2011) 0.90
Tocopherol succinate: modulation of antioxidant enzymes and oncogene expression, and hematopoietic recovery. Int J Radiat Oncol Biol Phys (2010) 0.90
Preclinical development of a bridging therapy for radiation casualties. Exp Hematol (2010) 0.90
Clinical significance of increased gelatinolytic activity in the rectal mucosa during external beam radiation therapy of prostate cancer. Int J Radiat Oncol Biol Phys (2002) 0.89
The combined effect of age and basal follicle-stimulating hormone on the cost of a live birth at assisted reproductive technology. Fertil Steril (2007) 0.89
Radiation-induced alterations in mitochondria of the rat heart. Radiat Res (2014) 0.88