Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.

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Published in Gastroenterology on June 09, 2010

Authors

Patricia A Thompson1, Betsy C Wertheim, Jason A Zell, Wen-Pin Chen, Christine E McLaren, Bonnie J LaFleur, Frank L Meyskens, Eugene W Gerner

Author Affiliations

1: Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724-5024, USA. pthompson@azcc.arizona.edu

Associated clinical trials:

Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps | NCT00118365

Eflornithine Plus Sulindac in Preventing Colorectal Cancer in Patients With Benign Colorectal Polyps | NCT00005882

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