Published in Cancer Epidemiol Biomarkers Prev on June 15, 2010
MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2). Proc Natl Acad Sci U S A (2010) 1.99
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Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. Br J Cancer (2011) 1.73
Epigenetics of colorectal cancer. Gastroenterology (2012) 1.60
Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer. Ann Surg (2014) 1.46
The role of microRNAs in colorectal cancer. Cancer J (2012) 1.44
Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer. BMC Cancer (2012) 1.30
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The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One (2012) 1.26
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Alterations of microRNAs contribute to colon carcinogenesis. Semin Oncol (2011) 1.19
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DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer. Biochem Biophys Res Commun (2014) 1.12
The prognostic value of microRNAs varies with patient race/ethnicity and stage of colorectal cancer. Clin Cancer Res (2013) 1.12
MicroRNA-21 as a potential colon and rectal cancer biomarker. World J Gastroenterol (2013) 1.10
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MiR-194 deregulation contributes to colorectal carcinogenesis via targeting AKT2 pathway. Theranostics (2014) 1.05
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Identification of serum microRNA profiles in colon cancer. Br J Cancer (2013) 1.02
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Exosome can prevent RNase from degrading microRNA in feces. J Gastrointest Oncol (2011) 1.01
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MicroRNAs (miRNAs) as biomarker(s) for prognosis and diagnosis of gastrointestinal (GI) cancers. Curr Pharm Des (2014) 0.90
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Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells. Exp Mol Med (2012) 0.90
Circulating microRNAs: molecular microsensors in gastrointestinal cancer. Sensors (Basel) (2012) 0.89
Implications of microRNAs in colorectal cancer development, diagnosis, prognosis, and therapeutics. Front Genet (2011) 0.88
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An update on microRNAs as colorectal cancer biomarkers: where are we and what's next? Expert Rev Mol Diagn (2014) 0.87
MiRNAs and LincRNAs: Could they be considered as biomarkers in colorectal cancer? Int J Mol Sci (2012) 0.87
MicroRNA in pancreatic ductal adenocarcinoma and its precursor lesions. World J Gastrointest Oncol (2016) 0.87
Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer. Gut (2015) 0.86
Diagnostic and therapeutic management of hepatocellular carcinoma. World J Gastroenterol (2015) 0.85
MicroRNA-645, up-regulated in human adencarcinoma of gastric esophageal junction, inhibits apoptosis by targeting tumor suppressor IFIT2. BMC Cancer (2014) 0.85
MicroRNAs in stool samples as potential screening biomarkers for pancreatic ductal adenocarcinoma cancer. Am J Cancer Res (2014) 0.84
MicroRNAs as diagnostic and prognostic biomarkers in colorectal cancer. World J Gastrointest Oncol (2016) 0.82
Are circulating microRNAs peripheral biomarkers for Alzheimer's disease? Biochim Biophys Acta (2016) 0.81
Differential expression of microRNAs in preneoplastic gastric mucosa. Sci Rep (2015) 0.81
Colorectal cancer characterization and therapeutic target prediction based on microRNA expression profile. Sci Rep (2016) 0.81
Clinical implications of microRNAs in cancer. Biotech Histochem (2013) 0.81
Fecal microRNA profile in patients with colorectal carcinoma before and after curative surgery. Int J Colorectal Dis (2015) 0.81
Cell-free nucleic acids as noninvasive biomarkers for colorectal cancer detection. Front Genet (2014) 0.80
Non-coding landscapes of colorectal cancer. World J Gastroenterol (2015) 0.80
A microRNA molecular modeling extension for prediction of colorectal cancer treatment. BMC Cancer (2015) 0.80
MicroRNAs: relevant tools for a colorectal surgeon? World J Surg (2012) 0.79
Exosomal miRNAs from Peritoneum Lavage Fluid as Potential Prognostic Biomarkers of Peritoneal Metastasis in Gastric Cancer. PLoS One (2015) 0.78
Quantitation of microRNA-92a in colorectal adenocarcinoma and its precancerous lesions: Co-utilization of in situ hybridization and spectral imaging. Oncol Lett (2014) 0.78
Colorectal cancer screening using protected microRNAs. J Gastrointest Oncol (2011) 0.78
Tissue Metabonomic Phenotyping for Diagnosis and Prognosis of Human Colorectal Cancer. Sci Rep (2016) 0.78
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A novel microRNA located in TrkC gene regulates Wnt signaling pathway and is differentially expressed in colorectal cancer specimens. J Biol Chem (2017) 0.78
The Structure and Clinical Roles of MicroRNA in Colorectal Cancer. Gastroenterol Res Pract (2016) 0.77
Downregulation of mir-23b in plasma is associated with poor prognosis in patients with colorectal cancer. Oncol Lett (2016) 0.77
MicroRNA miR-J1-5p as a potential biomarker for JC virus infection in the gastrointestinal tract. PLoS One (2014) 0.77
Biomarkers of Inflammatory Bowel Disease: From Classical Laboratory Tools to Personalized Medicine. Inflamm Bowel Dis (2015) 0.76
MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer. World J Gastroenterol (2016) 0.76
Feasibility of urinary microRNA profiling detection in intrahepatic cholestasis of pregnancy and its potential as a non-invasive biomarker. Sci Rep (2016) 0.76
MicroRNAs and Gastroenterological Cancers. Drug Discov Today Dis Mech (2011) 0.75
Investigation of MicroRNA-21 Expression Levels in Serum and Stool as a Potential Non-Invasive Biomarker for Diagnosis of Colorectal Cancer. Iran Biomed J (2016) 0.75
Epigenetic Biomarkers for the Early Detection of Gastrointestinal Cancer. Gastrointest Tumors (2015) 0.75
Simultaneous Underexpression of let-7a-5p and let-7f-5p microRNAs in Plasma and Stool Samples from Early Stage Colorectal Carcinoma. Biomark Cancer (2016) 0.75
Potential roles of microRNAs and ROS in colorectal cancer: diagnostic biomarkers and therapeutic targets. Oncotarget (2017) 0.75
MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications. Dis Model Mech (2017) 0.75
Regulatory miRNAs in Colorectal Carcinogenesis and Metastasis. Int J Mol Sci (2017) 0.75
Targeting MicroRNA in Cancer Using Plant-Based Proanthocyanidins. Diseases (2016) 0.75
Colorectal Cancer Screening: A Comprehensive Review to Recent Non-Invasive Methods. Int J Hematol Oncol Stem Cell Res (2017) 0.75
MicroRNAs as Biomarkers in Colorectal Cancer. Cancers (Basel) (2017) 0.75
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The functions of animal microRNAs. Nature (2004) 64.85
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Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A (2008) 33.65
Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res (2005) 29.17
Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study. N Engl J Med (1993) 27.80
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res (2008) 20.59
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res (2005) 18.58
lumi: a pipeline for processing Illumina microarray. Bioinformatics (2008) 17.19
Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology (2008) 15.86
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA (2008) 12.26
Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut (2009) 8.98
Detection of microRNA expression in human peripheral blood microvesicles. PLoS One (2008) 8.04
Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population. N Engl J Med (2004) 6.42
A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol (2009) 6.25
Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer (2009) 5.11
Clinical practice. Adenomatous polyps of the colon. N Engl J Med (2006) 4.22
Clinical practice. Screening for colorectal cancer. N Engl J Med (2009) 3.25
MicroRNA identification in plasma and serum: a new tool to diagnose and monitor diseases. Expert Opin Biol Ther (2009) 3.05
Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. J Natl Cancer Inst (2009) 2.57
Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest (2009) 2.43
Diagnostic microRNA markers for screening sporadic human colon cancer and active ulcerative colitis in stool and tissue. Cancer Genomics Proteomics (2009) 1.41
High detection rates of colorectal neoplasia by stool DNA testing with a novel digital melt curve assay. Gastroenterology (2008) 1.34
Early proliferative changes in gastrointestinal neoplasia. Am J Gastroenterol (1982) 1.08
Biomarkers in gastroenterology: between hope and hype comes histopathology. Am J Gastroenterol (2009) 1.02
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst (2004) 14.97
Microsatellite instability in colorectal cancer. Gastroenterology (2010) 7.39
Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing. Nature (2003) 5.04
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
VFDB: a reference database for bacterial virulence factors. Nucleic Acids Res (2005) 4.77
Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer. Gastroenterology (2004) 4.03
Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. J Natl Cancer Inst (2013) 4.03
Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228). Mol Microbiol (2003) 3.86
Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science (2008) 3.80
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56
Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Ann Intern Med (2011) 3.52
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. J Clin Invest (2012) 3.45
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Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy. J Genet Genomics (2012) 2.98
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Association between genetic variation of CACNA1H and childhood absence epilepsy. Ann Neurol (2003) 2.79
Identification of Lynch syndrome among patients with colorectal cancer. JAMA (2012) 2.77
Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients. J Clin Invest (2008) 2.73
The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer. Gastroenterology (2006) 2.63
GenomeComp: a visualization tool for microbial genome comparison. J Microbiol Methods (2003) 2.62
Cutaneous manifestations of gastrointestinal disease: part I. J Am Acad Dermatol (2013) 2.58
Lynch syndrome: form, function, proteins, and basketball. Gastroenterology (2005) 2.57
Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. J Natl Cancer Inst (2009) 2.57
MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut (2012) 2.40
Cutaneous manifestations of gastrointestinal disease: part II. J Am Acad Dermatol (2013) 2.38
Gamma-secretase gene mutations in familial acne inversa. Science (2010) 2.30
Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype. Kidney Int (2010) 2.28
Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res (2003) 2.24
Association of estrogen receptor alpha polymorphisms with susceptibility to chronic hepatitis B virus infection. Hepatology (2004) 2.12
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res (2004) 2.10
The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status. Eur J Cancer (2008) 2.08
Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines. Int J Cancer (2003) 2.07
A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis. Nat Genet (2011) 2.05
Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology (2008) 1.97
Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis. Cancer Res (2010) 1.88
Health Outcomes and Socio-Economic Status Among the Elderly in Gansu and Zhejiang Provinces, China: Evidence from the CHARLS Pilot. J Popul Ageing (2011) 1.87
Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. Gastroenterology (2007) 1.82
Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant. J Am Soc Nephrol (2012) 1.81
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Res (2008) 1.81
Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries. Proc Natl Acad Sci U S A (2012) 1.77
Clinical uses of microsatellite instability testing in colorectal cancer: an ongoing challenge. J Clin Oncol (2007) 1.73
5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer. Gastroenterology (2010) 1.71
Oxidative stress inactivates the human DNA mismatch repair system. Am J Physiol Cell Physiol (2002) 1.71
APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q. Cancer Biol Ther (2004) 1.71
Diagnosis and treatment of solid-pseudopapillary tumor of the pancreas. Hepatobiliary Pancreat Dis Int (2006) 1.71
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology (2005) 1.67
Microsatellite instability and DNA mismatch repair protein deficiency in Lynch syndrome colorectal polyps. Cancer Prev Res (Phila) (2012) 1.65
Cancer chemoprevention by dietary polyphenols: promising role for epigenetics. Biochem Pharmacol (2010) 1.63
Epigenetics of colorectal cancer. Gastroenterology (2012) 1.60
A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep (2012) 1.60
DNA microarray expression profiling of bladder cancer allows identification of noninvasive diagnostic markers. J Urol (2009) 1.59
Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications. Eur J Hum Genet (2006) 1.59
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone. Genomics (2007) 1.59
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat Struct Mol Biol (2011) 1.58
Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles. Hum Mol Genet (2009) 1.58
Characterization of γδ T cell subsets in organ transplantation. Transpl Int (2010) 1.57
Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer. Cancer Biol Ther (2004) 1.57
Risk of cancer in cases of suspected lynch syndrome without germline mutation. Gastroenterology (2013) 1.55
Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a. BMC Genomics (2006) 1.54
Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis. Gut (2012) 1.51
The Characteristics and Significance of Locally Infiltrating B Cells in Lupus Nephritis and Their Association with Local BAFF Expression. Int J Rheumatol (2013) 1.51
Prognostic value of microRNA expression pattern in upper tract urothelial carcinoma. BJU Int (2014) 1.49
Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer. Ann Surg (2014) 1.46
Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology (2010) 1.46
LDA--a java-based linkage disequilibrium analyzer. Bioinformatics (2003) 1.44
Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer. Gastroenterology (2008) 1.43
Molecular pathogenesis of colorectal cancer: implications for molecular diagnosis. Cancer (2005) 1.42
A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells. Clin Cancer Res (2003) 1.41
Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer. Int J Cancer (2011) 1.39
Genetic and epigenetic signatures in human hepatocellular carcinoma: a systematic review. Curr Genomics (2011) 1.39
Cocaine-induced acute hepatitis and thrombotic microangiopathy. JAMA (2005) 1.39