Published in Curr Opin Genet Dev on June 28, 2010
Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. EMBO J (2011) 2.55
Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer. Cell (2012) 2.05
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Mol Cell (2013) 2.05
Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest (2012) 1.55
Transcriptional enhancers in development and disease. Genome Biol (2012) 1.52
FOXA1: master of steroid receptor function in cancer. EMBO J (2011) 1.36
Serotonergic transcriptional networks and potential importance to mental health. Nat Neurosci (2012) 1.28
Androgen receptor-independent function of FoxA1 in prostate cancer metastasis. Cancer Res (2013) 1.26
Progesterone inhibits uterine gland development in the neonatal mouse uterus. Biol Reprod (2012) 1.21
Postnatal deletion of Wnt7a inhibits uterine gland morphogenesis and compromises adult fertility in mice. Biol Reprod (2011) 1.10
On the Origin of Cells and Derivation of Thyroid Cancer: C Cell Story Revisited. Eur Thyroid J (2016) 1.04
Role of estrogen in hepatocellular carcinoma: is inflammation the key? J Transl Med (2014) 0.99
Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility. Epigenetics Chromatin (2015) 0.97
Modulation of androgen receptor by FOXA1 and FOXO1 factors in prostate cancer. Int J Biol Sci (2014) 0.95
Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis. Genes Dev (2015) 0.95
Orchestrating liver development. Development (2015) 0.94
Foxa1 and Foxa2 are required for formation of the intervertebral discs. PLoS One (2013) 0.92
Interplay of estrogen receptors and FOXA factors in the liver cancer. Mol Cell Endocrinol (2015) 0.90
Fork head transcription factor is required for ovarian mature in the brown planthopper, Nilaparvata lugens (Stål). BMC Mol Biol (2011) 0.89
A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function. Thorax (2011) 0.88
Revising the embryonic origin of thyroid C cells in mice and humans. Development (2015) 0.88
FoxA family members are crucial regulators of the hypertrophic chondrocyte differentiation program. Dev Cell (2012) 0.88
Application of experimentally verified transcription factor binding sites models for computational analysis of ChIP-Seq data. BMC Genomics (2014) 0.88
Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance. Front Cell Neurosci (2014) 0.87
Role of forkhead box protein A3 in age-associated metabolic decline. Proc Natl Acad Sci U S A (2014) 0.87
FOXA1 promotes tumor cell proliferation through AR involving the Notch pathway in endometrial cancer. BMC Cancer (2014) 0.85
Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits. J Clin Endocrinol Metab (2014) 0.84
Impact of islet architecture on β-cell heterogeneity, plasticity and function. Nat Rev Endocrinol (2016) 0.84
Transcriptional and Chromatin Regulation during Fasting - The Genomic Era. Trends Endocrinol Metab (2015) 0.83
SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate. Oncotarget (2016) 0.83
FOXO flips the longevity SWItch. Nat Cell Biol (2013) 0.82
The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH. Sci Rep (2015) 0.82
Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum. BMC Genomics (2013) 0.82
FOXA1 defines cancer cell specificity. Sci Adv (2016) 0.81
Organ-specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA. Development (2013) 0.81
FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth. Nat Commun (2016) 0.81
Foxa1 is essential for mammary duct formation. Genesis (2016) 0.80
Effect of high fat diet on paternal sperm histone distribution and male offspring liver gene expression. Epigenetics (2015) 0.80
Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet (2014) 0.79
Genome-wide analysis reveals a major role in cell fate maintenance and an unexpected role in endoreduplication for the Drosophila FoxA gene Fork head. PLoS One (2011) 0.78
Forkhead box a2 (FOXA2) is essential for uterine function and fertility. Proc Natl Acad Sci U S A (2017) 0.78
Reconstruction of the gene regulatory network involved in the sonic hedgehog pathway with a potential role in early development of the mouse brain. PLoS Comput Biol (2014) 0.78
Association of the IGF1 gene with fasting insulin levels. Eur J Hum Genet (2016) 0.77
Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype? Pathogens (2012) 0.77
Androgen receptor epigenetics. Transl Androl Urol (2013) 0.77
VAV3 Overexpressed in Cancer Stem Cells Is a Poor Prognostic Indicator in Ovarian Cancer Patients. Stem Cells Dev (2015) 0.77
Calorie hoarding and thrifting: Foxa3 finds a way. Adipocyte (2015) 0.76
The mutational spectrum of FOXA2 in endometrioid endometrial cancer points to a tumor suppressor role. Gynecol Oncol (2016) 0.76
Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential. Nat Commun (2017) 0.75
Forkhead box A3 attenuated the progression of fibrosis in a rat model of biliary atresia. Cell Death Dis (2017) 0.75
Genes for regeneration. Elife (2014) 0.75
Hunting for Fox(A2): Dual roles in female fertility. Proc Natl Acad Sci U S A (2017) 0.75
Molecular Characterization of the Genital Organizer: Gene Expression Profile of the Mouse Urethral Plate Epithelium. J Urol (2016) 0.75
Beyond the brain-Peripheral kisspeptin signaling is essential for promoting endometrial gland development and function. Sci Rep (2016) 0.75
Forkhead box A3 mediates glucocorticoid receptor function in adipose tissue. Proc Natl Acad Sci U S A (2016) 0.75
Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol (2017) 0.75
Microsatellite and Single Nucleotide Polymorphisms in the Insulin-Like Growth Factor 1 Promoter with Insulin Sensitivity and Insulin Secretion. Med Sci Monit (2017) 0.75
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell (2005) 14.32
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell (2008) 14.18
Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. Mol Cell (2002) 8.59
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell (2004) 8.06
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature (1993) 7.56
Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev (2000) 5.36
Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science (2002) 4.33
From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc Natl Acad Sci U S A (2005) 4.16
HNF-3 beta is essential for node and notochord formation in mouse development. Cell (1994) 4.08
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev (1991) 4.01
The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell (1989) 3.95
The initiation of liver development is dependent on Foxa transcription factors. Nature (2005) 3.88
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell (1994) 3.71
Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development (1993) 3.63
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev (1990) 3.50
Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science (1999) 3.30
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature (2004) 3.29
Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development (1993) 3.25
The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development (1993) 3.22
The evolution of Fox genes and their role in development and disease. Nat Rev Genet (2009) 3.13
The fork head domain: a novel DNA binding motif of eukaryotic transcription factors? Cell (1990) 3.11
Transcription factors in liver development, differentiation, and regeneration. Hepatology (2003) 3.06
The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes. Mol Endocrinol (2003) 3.01
An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array. Cell (1993) 2.87
The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age. PLoS Biol (2007) 2.54
Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner. Development (2007) 2.40
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev (2008) 2.38
Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins. J Biol Chem (2000) 2.31
Foxa2 integrates the transcriptional response of the hepatocyte to fasting. Cell Metab (2005) 2.15
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem (2005) 2.15
Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins. Dev Biol (1999) 1.95
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Res (2009) 1.89
An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA. Mol Cell (1999) 1.86
FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (2010) 1.86
Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes. Mol Cell Biol (1995) 1.70
Foxa2 controls vesicle docking and insulin secretion in mature Beta cells. Cell Metab (2007) 1.66
Foxa2 regulates multiple pathways of insulin secretion. J Clin Invest (2004) 1.57
Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements. Proc Natl Acad Sci U S A (1993) 1.51
Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. Mol Endocrinol (2010) 1.47
Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development. Dev Biol (2009) 1.36
The Fox genes in the liver: from organogenesis to functional integration. Physiol Rev (2010) 1.13
Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids. Mol Endocrinol (1996) 1.10
Winged-helix transcription factors and pancreatic development. Clin Sci (Lond) (2005) 1.02
Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expression. PLoS One (2008) 0.99
Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation. Diabetes (2006) 0.98
Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation. Dev Dyn (2010) 0.96
The making of the liver: developmental competence in foregut endoderm and induction of the hepatogenic program. Cell Cycle (2005) 0.96
Foxa2-dependent hepatic gene regulatory networks depend on physiological state. Physiol Genomics (2009) 0.94
Correlated changes between regulatory cis elements and condition-specific expression in paralogous gene families. Nucleic Acids Res (2009) 0.85