Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.

PubWeight™: 11.55‹?› | Rank: Top 0.1%

🔗 View Article (PMC 2904878)

Published in Lancet on June 26, 2010

Authors

Emerging Risk Factors Collaboration1, N Sarwar, P Gao, S R Kondapally Seshasai, R Gobin, S Kaptoge, E Di Angelantonio, E Ingelsson, D A Lawlor, E Selvin, M Stampfer, C D A Stehouwer, S Lewington, L Pennells, A Thompson, N Sattar, I R White, K K Ray, J Danesh

Author Affiliations

1: Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK.

Associated clinical trials:

Effect of aSpirin Versus CilOstazol for Inhibition of Antiplatelet aggRegaTion in Type 2 DM Patients | NCT02933788

Carotid Atherosclerosis In Newly Diagnosed Type 2 Individuals (DIABIMCAP) | NCT01898572

Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients (MAGNA VICTORIA) | NCT01761318

The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes | NCT03771053

SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULTICENTER STUDY. SEVERAL STUDY. (SEVERAL) | NCT05136287

Articles citing this

(truncated to the top 100)

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 50.94

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet (2012) 17.29

Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med (2011) 10.33

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet (2011) 9.07

Prediabetes: a high-risk state for diabetes development. Lancet (2012) 6.42

C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39

Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials. BMJ (2011) 5.77

Multivariate meta-analysis: potential and promise. Stat Med (2011) 5.26

Chronic hyperglycemia and subclinical myocardial injury. J Am Coll Cardiol (2012) 3.91

Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial. Lancet (2014) 3.53

Risk of cancer in patients on insulin glargine and other insulin analogues in comparison with those on human insulin: results from a large population-based follow-up study. Diabetologia (2011) 3.52

Recommendations on screening for type 2 diabetes in adults. CMAJ (2012) 3.51

The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc (2012) 3.45

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people. Lancet Diabetes Endocrinol (2014) 2.59

Associations of pregnancy complications with calculated cardiovascular disease risk and cardiovascular risk factors in middle age: the Avon Longitudinal Study of Parents and Children. Circulation (2012) 2.54

Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis. Int J Epidemiol (2012) 2.48

Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent. Arch Intern Med (2011) 2.43

Do men develop type 2 diabetes at lower body mass indices than women? Diabetologia (2011) 2.12

Usual Blood Pressure and Risk of New-Onset Diabetes: Evidence From 4.1 Million Adults and a Meta-Analysis of Prospective Studies. J Am Coll Cardiol (2015) 2.12

Diabetes incidence and long-term exposure to air pollution: a cohort study. Diabetes Care (2011) 2.10

2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts)Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J (2016) 2.09

Effect of pre-diabetes on future risk of stroke: meta-analysis. BMJ (2012) 2.04

Cardiovascular outcomes in framingham participants with diabetes: the importance of blood pressure. Hypertension (2011) 2.02

On-pump versus off-pump coronary artery bypass graft surgery among patients with type 2 diabetes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial†. Eur J Cardiothorac Surg (2015) 2.00

The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One (2013) 1.95

Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials. PLoS Med (2012) 1.85

Mortality and other important diabetes-related outcomes with insulin vs other antihyperglycemic therapies in type 2 diabetes. J Clin Endocrinol Metab (2013) 1.83

Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study. Lancet Diabetes Endocrinol (2013) 1.64

Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice. J Clin Invest (2012) 1.63

Chronic ingestion of flavan-3-ols and isoflavones improves insulin sensitivity and lipoprotein status and attenuates estimated 10-year CVD risk in medicated postmenopausal women with type 2 diabetes: a 1-year, double-blind, randomized, controlled trial. Diabetes Care (2012) 1.58

Glycosylated hemoglobin in relationship to cardiovascular outcomes and death in patients with type 2 diabetes: a systematic review and meta-analysis. PLoS One (2012) 1.57

Intensive blood pressure treatment does not improve cardiovascular outcomes in centrally obese hypertensive individuals with diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Blood Pressure Trial. Diabetes Care (2012) 1.55

Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortality: prospective population based cohort study. BMJ (2010) 1.50

Ethnic Differences in Associations Between Blood Pressure and Stroke in South Asian and European Men. Hypertension (2015) 1.46

Diabetes and Cause-Specific Mortality in Mexico City. N Engl J Med (2016) 1.44

Time Trends in Ischemic Stroke among Type 2 Diabetic and Non-Diabetic Patients: Analysis of the Spanish National Hospital Discharge Data (2003-2012). PLoS One (2015) 1.43

Diabetes and cause-specific mortality in a prospective cohort of one million U.S. adults. Diabetes Care (2012) 1.42

Could NICE guidance on the choice of blood pressure lowering drugs be simplified? BMJ (2012) 1.41

Coronary calcium score and prediction of all-cause mortality in diabetes: the diabetes heart study. Diabetes Care (2011) 1.41

Pharmacist interventions to improve cardiovascular disease risk factors in diabetes: a systematic review and meta-analysis of randomized controlled trials. Diabetes Care (2012) 1.39

Cardiovascular risk assessment in patients with diabetes. Diabetol Metab Syndr (2017) 1.39

Managing diabetes with nanomedicine: challenges and opportunities. Nat Rev Drug Discov (2014) 1.39

Glycated hemoglobin measurement and prediction of cardiovascular disease. JAMA (2014) 1.36

Association of Cardiometabolic Multimorbidity With Mortality. JAMA (2015) 1.32

Trends in prevalence, awareness, treatment, and control of diabetes mellitus in mainland china from 1979 to 2012. Int J Endocrinol (2013) 1.32

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children. Diabetes (2011) 1.31

Pregnancy characteristics and women's future cardiovascular health: an underused opportunity to improve women's health? Epidemiol Rev (2013) 1.28

Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets. Drug Discov Today Dis Mech (2010) 1.28

Proresolution therapy for the treatment of delayed healing of diabetic wounds. Diabetes (2012) 1.27

Advanced glycation end products and oxidative stress in type 2 diabetes mellitus. Biomolecules (2015) 1.23

Characteristics associated with maintenance of mean A1C<6.5% in people with dysglycemia in the ORIGIN trial. Diabetes Care (2013) 1.18

Blood pressure j-curve: current concepts. Curr Hypertens Rep (2012) 1.18

Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care (2011) 1.15

The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities. Eur J Epidemiol (2014) 1.13

Oxidative stress in diabetes: implications for vascular and other complications. Int J Mol Sci (2013) 1.13

Risks and outcomes of living donation. Adv Chronic Kidney Dis (2012) 1.12

Rationale, design, and baseline characteristics of a randomized, placebo-controlled cardiovascular outcome trial of empagliflozin (EMPA-REG OUTCOME™). Cardiovasc Diabetol (2014) 1.12

Coronary calcium score predicts cardiovascular mortality in diabetes: diabetes heart study. Diabetes Care (2012) 1.12

Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity. Diabetes Metab Syndr Obes (2013) 1.12

Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice. Cardiovasc Diabetol (2014) 1.11

Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association. Diabetes Care (2015) 1.10

Validity of diabetes self-reports in the Saku diabetes study. J Epidemiol (2013) 1.10

Long-term and recent progress in blood pressure levels among U.S. adults with diagnosed diabetes, 1988-2008. Diabetes Care (2011) 1.09

International epidemiology of intracerebral hemorrhage. Curr Atheroscler Rep (2012) 1.09

Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes. Diabetes Obes Metab (2015) 1.08

Insulin resistance and risk of incident cardiovascular events in adults without diabetes: meta-analysis. PLoS One (2012) 1.07

Overweight in childhood, adolescence and adulthood and cardiovascular risk in later life: pooled analysis of three british birth cohorts. PLoS One (2013) 1.06

Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study. J Am Coll Cardiol (2012) 1.06

Diabetes mellitus, prediabetes, and incidence of subclinical myocardial damage. Circulation (2014) 1.05

Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus. Diabetes Metab Syndr Obes (2014) 1.05

Prediabetes diagnosis and treatment: A review. World J Diabetes (2015) 1.05

Mortality rates in trials of subjects with type 2 diabetes. J Am Heart Assoc (2012) 1.04

Subclinical hypothyroidism is independently associated with microalbuminuria in a cohort of prediabetic egyptian adults. Diabetes Metab J (2013) 1.04

Dietary glycemic index, glycemic load, and risk of coronary heart disease, stroke, and stroke mortality: a systematic review with meta-analysis. PLoS One (2012) 1.03

Impaired fasting glucose and risk of cardiovascular disease in Korean men and women: the Korean Heart Study. Diabetes Care (2012) 1.02

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat Commun (2014) 1.02

Impact of metabolic syndrome and its components on cardiovascular disease event rates in 4900 patients with type 2 diabetes assigned to placebo in the FIELD randomised trial. Cardiovasc Diabetol (2011) 1.02

Diabetes, markers of brain pathology and cognitive function: the Age, Gene/Environment Susceptibility-Reykjavik Study. Ann Neurol (2014) 1.01

Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women. Cardiovasc Diabetol (2013) 1.00

Psychological aspects of diabetes care: Effecting behavioral change in patients. World J Diabetes (2014) 0.99

Fasting glucose levels within the high normal range predict cardiovascular outcome. Am Heart J (2012) 0.99

The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities. Dis Model Mech (2014) 0.99

No evidence of an increased mortality risk associated with low levels of glycated haemoglobin in a non-diabetic UK population. Diabetologia (2011) 0.99

SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms? Diabetologia (2016) 0.98

The dipeptidyl peptidase (DPP)-4 inhibitors for type 2 diabetes mellitus in challenging patient groups. Adv Ther (2013) 0.98

Therapeutic effects of neuregulin-1 in diabetic cardiomyopathy rats. Cardiovasc Diabetol (2011) 0.98

The association of early post-transplant glucose levels with long-term mortality. Diabetologia (2011) 0.98

Aspirin for primary prevention of cardiovascular events: meta-analysis of randomized controlled trials and subgroup analysis by sex and diabetes status. PLoS One (2014) 0.98

A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease. Nat Commun (2015) 0.97

Statin Use, Diabetes Incidence and Overall Mortality in Normoglycemic and Impaired Fasting Glucose Patients. J Gen Intern Med (2016) 0.97

Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction. PLoS One (2016) 0.97

Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study. BMC Public Health (2011) 0.96

Prevalence and associated factors of diabetes and impaired fasting glucose in Chinese hypertensive adults aged 45 to 75 years. PLoS One (2012) 0.95

The impact of traditional cardiovascular risk factors on cardiovascular outcomes in patients with rheumatoid arthritis: a systematic review and meta-analysis. PLoS One (2015) 0.95

Type 2 diabetes mellitus and hypertension: an update. Endocrinol Metab Clin North Am (2013) 0.95

Sex differences in the risk of stroke and HbA(1c) among diabetic patients. Diabetologia (2014) 0.95

Effects of statin medication on mortality risk associated with type 2 diabetes in older persons: the population-based AGES-Reykjavik Study. BMJ Open (2011) 0.94

Diabetes mellitus in people with schizophrenia, bipolar disorder and major depressive disorder: a systematic review and large scale meta-analysis. World Psychiatry (2016) 0.94

Diabetes and Prior Coronary Heart Disease are Not Necessarily Risk Equivalent for Future Coronary Heart Disease Events. J Gen Intern Med (2015) 0.94

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS One (2012) 0.94

Articles cited by this

Quantifying heterogeneity in a meta-analysis. Stat Med (2002) 83.16

Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group. Stat Med (1991) 12.89

Major lipids, apolipoproteins, and risk of vascular disease. JAMA (2009) 10.58

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD). Eur Heart J (2007) 9.80

Global burden of obesity in 2005 and projections to 2030. Int J Obes (Lond) (2008) 9.45

The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care (1999) 9.16

Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA (2002) 8.81

Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies. BMJ (2005) 6.83

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I. Circulation (2003) 4.61

Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment. Lancet (2006) 4.26

Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies. Int J Epidemiol (2010) 3.97

The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81

Diabetes patients requiring glucose-lowering therapy and nondiabetics with a prior myocardial infarction carry the same cardiovascular risk: a population study of 3.3 million people. Circulation (2008) 3.23

Blood glucose and risk of cardiovascular disease in the Asia Pacific region. Diabetes Care (2004) 2.77

Explaining the sex difference in coronary heart disease mortality among patients with type 2 diabetes mellitus: a meta-analysis. Arch Intern Med (2002) 2.69

Emerging risk factors for coronary heart disease: a summary of systematic reviews conducted for the U.S. Preventive Services Task Force. Ann Intern Med (2009) 2.56

Impaired collateral vessel development in diabetes: potential cellular mechanisms and therapeutic implications. Cardiovasc Res (2001) 2.55

The effects of diabetes on the risks of major cardiovascular diseases and death in the Asia-Pacific region. Diabetes Care (2003) 2.36

Prospective study of type 1 and type 2 diabetes and risk of stroke subtypes: the Nurses' Health Study. Diabetes Care (2007) 2.33

Measures to assess the prognostic ability of the stratified Cox proportional hazards model. Stat Med (2009) 2.23

Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review. PLoS Med (2010) 2.02

Circulating concentrations of insulin markers and coronary heart disease: a quantitative review of 19 Western prospective studies. Eur Heart J (2007) 1.55

Coronary atherosclerosis in Type II diabetes: angiographic findings and clinical outcome. Diabetologia (2000) 1.54

Diabetes and modifiable risk factors for cardiovascular disease: the prospective Million Women Study. Eur J Epidemiol (2008) 1.42

Post-challenge hyperglycaemia rather than fasting hyperglycaemia is an independent risk factor of cardiovascular disease events. Clin Lab (2004) 1.27

Blood glucose levels: facing a global crisis. Lancet (2006) 1.27

Estimation of attributable number of deaths and standard errors from simple and complex sampled cohorts. Stat Med (2007) 1.26

Articles by these authors

Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol (2001) 24.36

Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science (2001) 18.43

Generation of influenza A viruses entirely from cloned cDNAs. Proc Natl Acad Sci U S A (1999) 14.90

Ribonucleic acid synthesis of vesicular stomatitis virus, II. An RNA polymerase in the virion. Proc Natl Acad Sci U S A (1970) 11.83

Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med (1996) 8.57

Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology (1998) 7.99

Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. JAMA (2008) 7.84

Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae. J Clin Microbiol (2007) 7.30

Structural basis of cell-cell adhesion by cadherins. Nature (1995) 6.56

Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies. Am J Epidemiol (1999) 6.42

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase. Cell (1991) 6.28

Spectrographic data concerning vitamin A and liver oils. Biochem J (1931) 6.14

Ribonucleic acid synthesis of vesicular stomatitis virus. 3. Multiple complementary messenger RNA molecules. Virology (1970) 5.99

EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis. Ann Rheum Dis (2009) 5.82

Ribonucleic acid synthesis of vesicular stomatitis virus. I. Species of ribonucleic acid found in Chinese hamster ovary cells infected with plaque-forming and defective particles. J Virol (1969) 5.73

Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell (1992) 5.29

X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli. Science (1999) 4.78

Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet (2001) 4.60

Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain (1999) 4.41

Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. Circulation (2001) 4.32

Production of acyl-homoserine lactone quorum-sensing signals by gram-negative plant-associated bacteria. Mol Plant Microbe Interact (1998) 4.28

The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81

Altered electrical properties in Drosophila neurons developing without synaptic transmission. J Neurosci (2001) 3.80

Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation (2001) 3.57

The Multiple Sclerosis Impact Scale (MSIS-29): a new patient-based outcome measure. Brain (2001) 3.51

Giardia and Cryptosporidium join the 'Neglected Diseases Initiative'. Trends Parasitol (2006) 3.34

Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. BMJ (1996) 3.27

Does the variation in the socioeconomic characteristics of an area affect mortality? BMJ (1996) 3.22

Glomerular hyperfiltration: a new marker of metabolic risk. Kidney Int (2007) 3.17

The crystal structure of dimeric kinesin and implications for microtubule-dependent motility. Cell (1997) 3.17

Chlamydia pneumoniae IgA titres and coronary heart disease; prospective study and meta-analysis. Eur Heart J (2002) 3.09

Diversity of TMPRSS2-ERG fusion transcripts in the human prostate. Oncogene (2006) 3.09

Translation of vesicular stomatitis messenger RNA by extracts from mammalian and plant cells. J Virol (1974) 3.06

Effect of the inflammatory response on trace element and vitamin status. Ann Clin Biochem (2000) 2.79

New weight guidelines for Americans: justified or injudicious? Am J Clin Nutr (1991) 2.75

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol (2013) 2.66

von Willebrand factor and coronary heart disease: prospective study and meta-analysis. Eur Heart J (2002) 2.66

An activating mutation of AKT2 and human hypoglycemia. Science (2011) 2.60

Structure of a cephalosporin synthase. Nature (1998) 2.59

Improved assessment of bone turnover by the PTH-(1-84)/large C-PTH fragments ratio in ESRD patients. Kidney Int (2001) 2.53

Coffee, caffeine, and cardiovascular disease in men. N Engl J Med (1990) 2.49

Absence of interference during high-multiplicity infection by clonally purified vesicular stomatitis virus. J Virol (1971) 2.48

Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis. Arterioscler Thromb Vasc Biol (2007) 2.45

Antineutrophil cytoplasmic antibodies, cystic fibrosis, and infection. Lancet (1991) 2.41

Growth of normal human mammary cells in culture. In Vitro (1980) 2.39

La Crosse encephalitis in children. N Engl J Med (2001) 2.38

Corticosteroid-induced suppression of the hypothalamo-pituitary-adrenal axis: observations on patients given oral corticosteroids for rheumatoid arthritis. Q J Med (1967) 2.38

Missed appointments in general practice: retrospective data analysis from four practices. Br J Gen Pract (2001) 2.33

The Evaluation of Screening and Early Detection Strategies for Type 2 Diabetes and Impaired Glucose Tolerance (DETECT-2) update of the Finnish diabetes risk score for prediction of incident type 2 diabetes. Diabetologia (2010) 2.33

Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial. J Intern Med (2003) 2.28

C-reactive protein and coronary heart disease: a critical review. J Intern Med (2008) 2.25

Vasopressin administration facilitates fluid removal during hemodialysis. Kidney Int (2006) 2.23

Doppler echocardiographic measurement of low velocity motion of the left ventricular posterior wall. Am J Cardiol (1989) 2.23

Automation of sample mounting for macromolecular crystallography. Acta Crystallogr D Biol Crystallogr (2006) 2.22

Diabetes, prediabetes and cancer mortality. Diabetologia (2010) 2.22

The pathophysiology of HOX genes and their role in cancer. J Pathol (2005) 2.18

Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes--the EURODIAB Prospective Complications Study. Diabetologia (2005) 2.16

Increase of oleic acid in erythrocytes associated with malignancies. Br Med J (Clin Res Ed) (1985) 2.15

Systematic review of the prospective cohort studies on meat consumption and colorectal cancer risk: a meta-analytical approach. Cancer Epidemiol Biomarkers Prev (2001) 2.14

Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant meta-analysis of 154,211 adults in 31 prospective studies: the fibrinogen studies collaboration. Am J Epidemiol (2007) 2.13

Do men develop type 2 diabetes at lower body mass indices than women? Diabetologia (2011) 2.12

Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium. J Cell Sci (1989) 2.07

Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study. Diabetologia (2011) 2.06

Vitamin D status and redefining serum parathyroid hormone reference range in the elderly. J Clin Endocrinol Metab (2001) 2.05

Nature of polymorphism in HLA-A, -B, and -C molecules. Proc Natl Acad Sci U S A (1988) 2.05

Interpreting lipid levels in the context of high-grade inflammatory states with a focus on rheumatoid arthritis: a challenge to conventional cardiovascular risk actions. Ann Rheum Dis (2009) 2.03

Glycated haemoglobin and cognitive decline: the Atherosclerosis Risk in Communities (ARIC) study. Diabetologia (2011) 2.03

Semi-automatic assessment of skin capillary density: proof of principle and validation. Microvasc Res (2013) 2.01

Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies. J Thromb Haemost (2005) 1.99

Association of existing diabetes, gestational diabetes and glycosuria in pregnancy with macrosomia and offspring body mass index, waist and fat mass in later childhood: findings from a prospective pregnancy cohort. Diabetologia (2009) 1.99

Comparison of ultrasound measurements at the heel between adults with mental retardation and control subjects. Bone (1998) 1.97

[Chronic renal disease as cardiovascular risk factor]. Ned Tijdschr Geneeskd (2008) 1.94

During infection of epithelial cells Salmonella enterica serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems. Cell Microbiol (2007) 1.94

Assessment of questionnaire validity for measuring total fat intake using plasma lipid levels as criteria. Am J Epidemiol (2001) 1.91

Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK. Diabetologia (2006) 1.90

External validity of randomized controlled trials of glycaemic control and vascular disease: how representative are participants? Diabet Med (2013) 1.90

MRI criteria for MS in patients with clinically isolated syndromes. Neurology (2010) 1.90

Low grade chronic inflammation in women with polycystic ovarian syndrome. J Clin Endocrinol Metab (2001) 1.89

Kurtzke scales revisited: the application of psychometric methods to clinical intuition. Brain (2000) 1.89

The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis. Mol Psychiatry (2006) 1.88

A novel mechanism for skeletal resistance in uremia. Kidney Int (2000) 1.88

Interspecies transmission of influenza viruses: H5N1 virus and a Hong Kong SAR perspective. Vet Microbiol (2000) 1.86