Stephen M Jane

Author PubWeight™ 56.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science 2005 2.72
2 The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science 2010 2.64
3 Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood 2004 2.30
4 The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proc Natl Acad Sci U S A 2003 2.12
5 Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors. Blood 2002 1.83
6 A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead. Mech Dev 2002 1.64
7 Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell 2011 1.63
8 Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3. Nat Med 2003 1.51
9 Perturbed desmosomal cadherin expression in grainy head-like 1-null mice. EMBO J 2008 1.42
10 Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development. Gene Expr Patterns 2006 1.35
11 Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation. J Immunol 2002 1.31
12 Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression. Blood 2010 1.28
13 Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell 2010 1.25
14 Regional neural tube closure defined by the Grainy head-like transcription factors. Dev Biol 2010 1.23
15 SCL is required for normal function of short-term repopulating hematopoietic stem cells. Blood 2004 1.20
16 Distinct domains of erythroid Krüppel-like factor modulate chromatin remodeling and transactivation at the endogenous beta-globin gene promoter. Mol Cell Biol 2002 1.17
17 The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity. Dev Biol 2010 1.17
18 Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection. Blood 2005 1.10
19 The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors. Biochem J 2003 1.10
20 The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene. J Exp Med 2004 1.05
21 Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant. Blood 2009 1.04
22 A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells. Cancer Gene Ther 2004 1.03
23 BMP4-dependent expression of Xenopus Grainyhead-like 1 is essential for epidermal differentiation. Development 2005 1.02
24 Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene. Mol Cell Biol 2005 1.02
25 Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene. Blood 2007 1.01
26 Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter. Blood 2005 1.00
27 The role of p22 NF-E4 in human globin gene switching. J Biol Chem 2004 0.99
28 Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1. J Biol Chem 2004 0.99
29 Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors. Mol Cell Biol 2002 0.98
30 Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters. Mol Cell Biol 2006 0.97
31 The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms. Blood 2009 0.95
32 A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis. Blood 2006 0.94
33 Defective extraembryonic angiogenesis in mice lacking LBP-1a, a member of the grainyhead family of transcription factors. Mol Cell Biol 2004 0.92
34 Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome. Blood 2012 0.90
35 Grhl3 and Lmo4 play coordinate roles in epidermal migration. Dev Biol 2008 0.89
36 ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level. Blood Cells Mol Dis 2012 0.88
37 The planar cell polarity pathway in vertebrate epidermal development, homeostasis and repair. Organogenesis 2011 0.87
38 The epidermis of grhl3-null mice displays altered lipid processing and cellular hyperproliferation. Organogenesis 2005 0.85
39 Novel mechanisms that pattern and shape the midbrain-hindbrain boundary. Cell Mol Life Sci 2013 0.84
40 Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways. Development 2012 0.82
41 The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors. Mol Cell Biol 2010 0.81
42 An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation. Blood 2011 0.79
43 Identification and characterization of mechanistically distinct inducers of gamma-globin transcription. Biochem Pharmacol 2003 0.78
44 Grhl3 and GEF19 in the front rho. Small GTPases 2010 0.78
45 The role of WDR5 in silencing human fetal globin gene expression. Haematologica 2012 0.78
46 Regulation of delta-aminolevulinic acid dehydratase by krüppel-like factor 1. PLoS One 2012 0.77
47 Induction of human fetal hemoglobin expression by adenosine-2',3'-dialdehyde. J Transl Med 2013 0.75
48 T cells gene-engineered with DAP12 mediate effector function in an NKG2D-dependent and major histocompatibility complex-independent manner. J Biol Chem 2005 0.75