Published in Chem Senses on July 21, 2010
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res (2011) 1.60
Glucose transporters and ATP-gated K+ (KATP) metabolic sensors are present in type 1 taste receptor 3 (T1r3)-expressing taste cells. Proc Natl Acad Sci U S A (2011) 1.46
Evaluation of the Monell forced-choice, paired-comparison tracking procedure for determining sweet taste preferences across the lifespan. Chem Senses (2011) 1.35
"Liking" and "wanting" linked to Reward Deficiency Syndrome (RDS): hypothesizing differential responsivity in brain reward circuitry. Curr Pharm Des (2012) 1.31
Do polymorphisms in chemosensory genes matter for human ingestive behavior? Food Qual Prefer (2013) 0.97
Functional roles of the sweet taste receptor in oral and extraoral tissues. Curr Opin Clin Nutr Metab Care (2014) 0.88
Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. Obesity (Silver Spring) (2012) 0.86
Genetic loss or pharmacological blockade of testes-expressed taste genes causes male sterility. Proc Natl Acad Sci U S A (2013) 0.86
Receptor Polymorphism and Genomic Structure Interact to Shape Bitter Taste Perception. PLoS Genet (2015) 0.83
Taste perception, associated hormonal modulation, and nutrient intake. Nutr Rev (2015) 0.81
The role of sweet taste in satiation and satiety. Nutrients (2014) 0.81
Do polymorphisms in the TAS1R1 gene contribute to broader differences in human taste intensity? Chem Senses (2013) 0.79
Individual Differences Among Children in Sucrose Detection Thresholds: Relationship With Age, Gender, and Bitter Taste Genotype. Nurs Res (2015) 0.78
The development of sweet taste: From biology to hedonics. Rev Endocr Metab Disord (2016) 0.78
Gustation genetics: sweet gustducin! Chem Senses (2010) 0.78
Is the Association Between Sweet and Bitter Perception due to Genetic Variation? Chem Senses (2016) 0.75
Salty taste acuity is affected by the joint action of αENaC A663T gene polymorphism and available zinc intake in young women. Nutrients (2013) 0.75
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Positive natural selection in the human lineage. Science (2006) 12.55
Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell (2003) 5.95
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Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science (2003) 4.48
Detection of genotyping errors by Hardy-Weinberg equilibrium testing. Eur J Hum Genet (2004) 2.65
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Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet (2008) 1.98
Heritability estimates for dental caries and sucrose sweetness preference. Arch Oral Biol (2006) 1.96
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet (2004) 1.56
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Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden. Am J Hum Genet (2006) 1.50
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Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants. Am J Hum Genet (2007) 1.39
Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol (2009) 1.39
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Umami taste responses are mediated by alpha-transducin and alpha-gustducin. J Neurosci (2004) 1.36
Contribution of alpha-gustducin to taste-guided licking responses of mice. Chem Senses (2005) 1.26
Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine. Chem Senses (2006) 1.24
Sweet taste preferences are partly genetically determined: identification of a trait locus on chromosome 16. Am J Clin Nutr (2007) 1.17
Dominant loss of responsiveness to sweet and bitter compounds caused by a single mutation in alpha -gustducin. Proc Natl Acad Sci U S A (2001) 1.14
Perceptual variation in umami taste and polymorphisms in TAS1R taste receptor genes. Am J Clin Nutr (2009) 1.11
The relationship between phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) taster status and taste thresholds for sucrose and quinine. Arch Oral Biol (2005) 1.10
Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance. Diabet Med (2006) 1.07
Alternative promoter usage of the membrane glycoprotein CD36. BMC Mol Biol (2006) 1.05
Twin study of the heritability of recognition thresholds for sour and salty taste. Chem Senses (2007) 1.03
Tonic activity of Galpha-gustducin regulates taste cell responsivity. FEBS Lett (2008) 0.99
Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin. Chem Senses (2002) 0.98
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GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate. J Hum Hypertens (2004) 0.82
The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II. Genes Immun (2008) 0.82
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Taste sensitivity to sodium chloride and sucrose in a group of adolescent children in Northern Nigeria. Ethn Dis (2000) 0.78
Mutant dynactin in motor neuron disease. Nat Genet (2003) 5.28
Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science (2003) 4.48
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr Biol (2005) 3.41
Mutations in the lysosomal enzyme-targeting pathway and persistent stuttering. N Engl J Med (2010) 3.09
Natural selection and molecular evolution in PTC, a bitter-taste receptor gene. Am J Hum Genet (2004) 2.33
Bitter taste receptors for saccharin and acesulfame K. J Neurosci (2004) 2.09
Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci. Hum Mutat (2005) 1.50
Results of a genome-wide linkage scan for stuttering. Am J Med Genet A (2004) 1.42
Genomewide significant linkage to stuttering on chromosome 12. Am J Hum Genet (2005) 1.42
Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol (2009) 1.39
Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats. Neuroreport (2010) 1.34
The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor. BMC Struct Biol (2007) 1.17
Variation in the human TAS1R taste receptor genes. Chem Senses (2006) 1.14
Naturally occurring hypothermia is more advantageous than fever in severe forms of lipopolysaccharide- and Escherichia coli-induced systemic inflammation. Am J Physiol Regul Integr Comp Physiol (2012) 1.10
Modulation of bitter taste perception by a small molecule hTAS2R antagonist. Curr Biol (2010) 1.09
Pathogenic effects of a novel mutation (c.664_681del) in KCNQ4 channels associated with auditory pathology. Biochim Biophys Acta (2010) 1.09
Opioid modulation of scratching and spinal c-fos expression evoked by intradermal serotonin. J Neurosci (2003) 1.08
Antinociception induced by chronic exposure of rats to cigarette smoke. Neurosci Lett (2004) 1.06
Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. Mol Biol Evol (2011) 1.05
Modeling the human PTC bitter-taste receptor interactions with bitter tastants. J Mol Model (2006) 1.05
Identification of an autosomal recessive stuttering locus on chromosome 3q13.2-3q13.33. Hum Genet (2010) 1.04
Deletion of the preprotachykinin A gene in mice does not reduce scratching behavior elicited by intradermal serotonin. Neurosci Lett (2003) 1.02
Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus. Neurosci Lett (2004) 1.01
Genetics of speech and language disorders. Annu Rev Genomics Hum Genet (2011) 0.99
Phonological processing in adults with deficits in musical pitch recognition. J Commun Disord (2009) 0.96
The organum vasculosum laminae terminalis in immune-to-brain febrigenic signaling: a reappraisal of lesion experiments. Am J Physiol Regul Integr Comp Physiol (2003) 0.94
A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats. J Neurophysiol (2011) 0.91
Psychophysical evaluation of a sanshool derivative (alkylamide) and the elucidation of mechanisms subserving tingle. PLoS One (2010) 0.91
Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. Mol Biol Evol (2013) 0.90
Widespread auditory deficits in tune deafness. Ear Hear (2009) 0.89
C-fos induction in rat superficial dorsal horn following cutaneous application of noxious chemical or mechanical stimuli. Exp Brain Res (2002) 0.88
Characterization of a mutation commonly associated with persistent stuttering: evidence for a founder mutation. J Hum Genet (2010) 0.85
Analysis of mannose 6-phosphate uncovering enzyme mutations associated with persistent stuttering. J Biol Chem (2011) 0.85
Studies in a consanguineous family reveal a novel locus for stuttering on chromosome 16q. Hum Genet (2011) 0.85
Time course of self-desensitization of oral irritation by nicotine and capsaicin. Chem Senses (2007) 0.84
Activation of lumbar spinal wide-dynamic range neurons by a sanshool derivative. J Neurophysiol (2009) 0.84
Trigeminal modulation of gustatory neurons in the nucleus of the solitary tract. Brain Res (2003) 0.84
Linkage analysis of a large African family segregating stuttering suggests polygenic inheritance. Hum Genet (2012) 0.83
In vitro evaluation of flavonoids from Eriodictyon californicum for antagonist activity against the bitterness receptor hTAS2R31. J Agric Food Chem (2011) 0.81
Novel menthol-derived cooling compounds activate primary and second-order trigeminal sensory neurons and modulate lingual thermosensitivity. Chem Senses (2011) 0.81
A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait. Hum Genet (2007) 0.80
Tune deafness: processing melodic errors outside of conscious awareness as reflected by components of the auditory ERP. PLoS One (2008) 0.80
Sensitization of trigeminal caudalis neuronal responses to intraoral acid and salt stimuli and desensitization by nicotine. Pain (2002) 0.79
A role for inherited metabolic deficits in persistent developmental stuttering. Mol Genet Metab (2012) 0.78
Genetic variation in taste receptor pseudogenes provides evidence for a dynamic role in human evolution. BMC Evol Biol (2014) 0.78
Sarco/Endoplasmic reticulum Ca2+-ATPases (SERCA) contribute to GPCR-mediated taste perception. PLoS One (2011) 0.78
G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey. Curr Top Med Chem (2011) 0.77
Evaluation of the association between polymorphisms at the DRD2 locus and stuttering. J Hum Genet (2011) 0.77
In vitro evaluation of potential bitterness-masking terpenoids from the Canada goldenrod (Solidago canadensis). J Nat Prod (2014) 0.77
Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride. Brain Res (2003) 0.76
Bioelectronic tongue using heterodimeric human taste receptor for the discrimination of sweeteners with human-like performance. ACS Nano (2014) 0.75
Corrigendum: Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal. Sci Rep (2016) 0.75
Raspberry ketone fails to reduce adiposity beyond decreasing food intake in C57BL/6 mice fed a high-fat diet. Food Funct (2017) 0.75
Addressing Consumer Confusion Surrounding "Natural" Food Claims. Am J Law Med (2015) 0.75