Published in J Org Chem on August 20, 2010
Greener approaches to organic synthesis using microreactor technology. Chem Rev (2007) 1.97
Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS. J Am Chem Soc (2006) 1.81
Enantioselective Pictet-Spengler-type cyclizations of hydroxylactams: H-bond donor catalysis by anion binding. J Am Chem Soc (2007) 1.80
Chiral Brønsted acid-catalyzed direct Mannich reactions via electrophilic activation. J Am Chem Soc (2004) 1.76
Cyclizations of N-acyliminium ions. Chem Rev (2004) 1.72
Chemistry in microstructured reactors. Angew Chem Int Ed Engl (2004) 1.68
Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo[3.2.1]octanoid scaffolds. J Org Chem (2009) 1.34
Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system. Lab Chip (2003) 1.30
Combinatorial and Evolution-Based Methods in the Creation of Enantioselective Catalysts. Angew Chem Int Ed Engl (2001) 1.27
Flash chemistry: fast chemical synthesis by using microreactors. Chemistry (2008) 1.24
Integrated microfluidics for parallel screening of an in situ click chemistry library. Angew Chem Int Ed Engl (2006) 1.24
A new reaction of nitriles; amides from alkenes and mononitriles. J Am Chem Soc (1948) 1.23
Organocatalytic asymmetric aza-Friedel-Crafts alkylation of furan. J Am Chem Soc (2004) 1.22
Brønsted acid-catalyzed imine amidation. J Am Chem Soc (2005) 1.14
Advanced organic synthesis using microreactor technology. Org Biomol Chem (2006) 1.10
Regio- and enantioselective catalytic cyclization of pyrroles onto N-acyliminium ions. Org Lett (2008) 1.08
Accelerating reactions with microreactors at elevated temperatures and pressures: profiling aminocarbonylation reactions. Angew Chem Int Ed Engl (2007) 1.06
Enantioselective friedel-crafts reaction of electron-rich alkenes catalyzed by chiral Brønsted acid. J Am Chem Soc (2007) 1.05
Catalytic asymmetric addition of alcohols to imines: enantioselective preparation of chiral N,O-aminals. J Am Chem Soc (2008) 1.04
Enantioselective Brønsted acid-catalyzed N-acyliminium cyclization cascades. J Am Chem Soc (2009) 1.03
Multicomponent approach to the synthesis of oxidized amides through nitrile hydrozirconation. Org Lett (2007) 1.03
Multiphase organic synthesis in microchannel reactors. Chem Asian J (2006) 1.01
Combinatorial libraries of chiral ligands for enantioselective catalysis. Chem Rev (2003) 1.00
One-pot synthesis of bicyclic beta-alkoxy amides from cyanohydrin ethers. Org Lett (2008) 0.98
A comprehensive self-consistent spectrophotometric acidity scale of neutral Brønsted acids in acetonitrile. J Org Chem (2006) 0.98
Microreactor-based reaction optimization in organic chemistry--glycosylation as a challenge. Chem Commun (Camb) (2004) 0.97
Enantioselective, thiourea-catalyzed intermolecular addition of indoles to cyclic N-acyl iminium ions. Angew Chem Int Ed Engl (2009) 0.97
Multicomponent synthesis of alpha-branched amides. Org Lett (2009) 0.94
"Cation flow" method: a new approach to conventional and combinatorial organic syntheses using electrochemical microflow systems. J Am Chem Soc (2001) 0.94
Double bond isomerization/enantioselective aza-Petasis-Ferrier rearrangement sequence as an efficient entry to anti- and enantioenriched beta-amino aldehydes. J Am Chem Soc (2009) 0.92
The highly enantioselective addition of indoles to N-acyl imines with use of a chiral phosphoric acid catalyst. Org Lett (2007) 0.91
Activation of hemiaminal ethers by chiral Brønsted acids for facile access to enantioselective two-carbon homologation using enecarbamates. Angew Chem Int Ed Engl (2009) 0.88
Micro reactors: a new tool for the synthetic chemist. Org Biomol Chem (2007) 0.86
Continuous flow microreactors for drug discovery. Curr Opin Drug Discov Devel (2004) 0.85
Highly enantioselective hydrogenation of enamides catalyzed by chiral phosphoric acids. Org Lett (2009) 0.83
Chiral brønsted acid-catalyzed tandem aza-ene type reaction/cyclization cascade for a one-pot entry to enantioenriched piperidines. J Am Chem Soc (2007) 0.83
Organocatalytic enantioselective Friedel-Crafts reaction of pyrrole derivatives with imines. Org Lett (2007) 0.81
Ultrahigh-pressure liquid chromatography using a 1-mm id column packed with 1.5-microm porous particles. J Sep Sci (2007) 0.81
Capillary-based, serial-loading, parallel microreactor for catalyst screening. Anal Chem (2006) 0.77
Severe eczema vaccinatum in a household contact of a smallpox vaccinee. Clin Infect Dis (2008) 2.00
Total synthesis of (+)-dactylolide through an efficient sequential Peterson olefination and Prins cyclization reaction. Angew Chem Int Ed Engl (2005) 2.00
Glycopeptides are no more effective than beta-lactam agents for prevention of surgical site infection after cardiac surgery: a meta-analysis. Clin Infect Dis (2004) 1.87
An experimental and computational approach to defining structure/reactivity relationships for intramolecular addition reactions to bicyclic epoxonium ions. J Am Chem Soc (2007) 1.70
Rotavirus infection in adults. Lancet Infect Dis (2004) 1.65
High-throughput sequence determination of cyclic peptide library members by partial Edman degradation/mass spectrometry. J Am Chem Soc (2006) 1.45
Single-cell electroporation. Curr Opin Biotechnol (2003) 1.45
Diastereoselective tetrahydropyrone synthesis through transition-metal-free oxidative carbon-hydrogen bond activation. Angew Chem Int Ed Engl (2008) 1.43
The impact of mechanical bowel preparation on postoperative complications for patients undergoing cystectomy and urinary diversion. J Urol (2012) 1.41
Stereocontrolled creation of adjacent quaternary and tertiary stereocenters by a catalytic conjugate addition. Angew Chem Int Ed Engl (2004) 1.39
Prior antimicrobial therapy and risk for hospital-acquired Candida glabrata and Candida krusei fungemia: a case-case-control study. Antimicrob Agents Chemother (2005) 1.34
Two cases of necrotizing fasciitis due to Acinetobacter baumannii. J Clin Microbiol (2008) 1.30
Management of outbreaks of methicillin-resistant Staphylococcus aureus infection in the neonatal intensive care unit: a consensus statement. Infect Control Hosp Epidemiol (2006) 1.30
Tuning reactivity and chemoselectivity in electron transfer initiated cyclization reactions: applications to carbon-carbon bond formation. J Am Chem Soc (2003) 1.27
Oxidative carbocation formation in macrocycles: synthesis of the neopeltolide macrocycle. Angew Chem Int Ed Engl (2009) 1.26
Effect of dexamethasone on gliosis, ischemia, and dopamine extraction during microdialysis sampling in brain tissue. Anal Chem (2011) 1.20
Fabrication of microchannel structures in fluorinated ethylene propylene. Anal Chem (2002) 1.19
Control of diastereoselectivity in tandem asymmetric reactions generating nonadjacent stereocenters with bifunctional catalysis by cinchona alkaloids. J Am Chem Soc (2007) 1.15
Synthesis of the C16-C35 fragment of integramycin using olefin hydroesterification as a linchpin reaction. Org Lett (2004) 1.10
Impact of microdialysis probes on vasculature and dopamine in the rat striatum: a combined fluorescence and voltammetric study. J Neurosci Methods (2008) 1.09
Structurally and stereochemically diverse tetrahydropyran synthesis through oxidative C-H bond activation. Angew Chem Int Ed Engl (2010) 1.07
Concise and stereoselective synthesis of the N7-C25 fragment of psymberin. Org Lett (2005) 1.06
In vitro biomarker discovery for atherosclerosis by proteomics. Mol Cell Proteomics (2004) 1.04
Total synthesis of theopederin D. Angew Chem Int Ed Engl (2008) 1.04
Mechanistic Analysis of Oxidative C-H Cleavages Using Inter- and Intramolecular Kinetic Isotope Effects. Tetrahedron (2009) 1.04
Cyclization reactions through DDQ-mediated vinyl oxazolidinone oxidation. Org Lett (2009) 1.04
Structure-reactivity relationships in oxidative carbon-carbon bond forming reactions: a mild and efficient approach to stereoselective syntheses of 2,6-disubstituted tetrahydropyrones. J Am Chem Soc (2004) 1.04
Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs. J Am Chem Soc (2011) 1.04
Multicomponent approach to the synthesis of oxidized amides through nitrile hydrozirconation. Org Lett (2007) 1.03
Oxidative cleavage in the construction of complex molecules: synthesis of the leucascandrolide A macrolactone. Angew Chem Int Ed Engl (2007) 1.03
Analysis of the performance of a flow reactor for use with microcolumn HPLC. Anal Chem (2004) 1.03
miR-29b suppresses CML cell proliferation and induces apoptosis via regulation of BCR/ABL1 protein. Exp Cell Res (2013) 1.01
Stereochemical assignment of the C1-C6 fragment of psymberin by synthesis and natural product degradation. Org Lett (2005) 1.01
Stereoselective synthesis of tertiary ethers through geometric control of highly substituted oxocarbenium ions. Angew Chem Int Ed Engl (2010) 1.00
Determination of zeta-potential in rat organotypic hippocampal cultures. Biophys J (2008) 0.99
High-throughput screening of one-bead-one-compound libraries: identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction. ACS Comb Sci (2011) 0.99
One-pot synthesis of bicyclic beta-alkoxy amides from cyanohydrin ethers. Org Lett (2008) 0.98
Extraction of pyridines into fluorous solvents based on hydrogen bond complex formation with carboxylic acid receptors. Anal Chem (2007) 0.98
Electron transfer initiated heterogenerative cascade cyclizations: polyether synthesis under nonacidic conditions. Org Lett (2002) 0.98
Stereoselective synthesis of spirooxindole amides through nitrile hydrozirconation. Org Lett (2010) 0.97
Eczema vaccinatum resulting from the transmission of vaccinia virus from a smallpox vaccinee: an investigation of potential fomites in the home environment. Vaccine (2008) 0.97
Effect of cell size and shape on single-cell electroporation. Anal Chem (2007) 0.97
Optimization for speed and sensitivity in capillary high performance liquid chromatography. The importance of column diameter in online monitoring of serotonin by microdialysis. J Chromatogr A (2012) 0.96
Differential effects of levofloxacin and ciprofloxacin on the risk for isolation of quinolone-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother (2006) 0.95
The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK. Glia (2011) 0.95
Single-cell electroporation. Anal Bioanal Chem (2010) 0.95
Simple method for the quantitative examination of extra column band broadening in microchromatographic systems. J Chromatogr A (2003) 0.95
Transmission of methicillin-resistant Staphylococcus aureus to preterm infants through breast milk. Infect Control Hosp Epidemiol (2004) 0.95
Multicomponent synthesis of alpha-branched amides. Org Lett (2009) 0.94
Effects of hemicellulose removal on cellulose fiber structure and recycling characteristics of eucalyptus pulp. Bioresour Technol (2010) 0.93
Construction of a bicyclic beta-benzyloxy and beta-hydroxy amide library through a multicomponent cyclization reaction. J Comb Chem (2010) 0.93
Capillary ultrahigh performance liquid chromatography with elevated temperature for sub-one minute separations of basal serotonin in submicroliter brain microdialysate samples. Anal Chem (2010) 0.93
Stimulated efflux of amino acids and glutathione from cultured hippocampal slices by omission of extracellular calcium: likely involvement of connexin hemichannels. J Biol Chem (2008) 0.93
Influence of chemical kinetics on postcolumn reaction in a capillary Taylor reactor with catechol analytes and photoluminescence following electron transfer. Anal Chem (2005) 0.92
Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration. J Am Chem Soc (2008) 0.92
Per2 inhibits k562 leukemia cell growth in vitro and in vivo through cell cycle arrest and apoptosis induction. Pathol Oncol Res (2009) 0.92
Clostridium difficile outbreak strain BI is highly endemic in Chicago area hospitals. Infect Control Hosp Epidemiol (2011) 0.91
Inhibition of BCR/ABL protein expression by miR-203 sensitizes for imatinib mesylate. PLoS One (2013) 0.91
Minimizing tissue damage in electroosmotic sampling. Anal Chem (2010) 0.91
High-throughput method for lipophilicity measurement. Anal Chem (2007) 0.91
Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products. Nat Prod Rep (2012) 0.90
An oxidative entry into the amido trioxadecalin ring system. Org Lett (2003) 0.90
A screening method for chiral selectors that does not require covalent attachment. J Am Chem Soc (2006) 0.90
Transport of organic solutes through amorphous teflon AF films. J Am Chem Soc (2005) 0.89
Rhodium(II)-catalyzed cyclization of bis(N-tosylhydrazone)s: an efficient approach towards polycyclic aromatic compounds. Angew Chem Int Ed Engl (2012) 0.88
Accuracy of a local surveillance system for early detection of emerging infectious disease. JAMA (2003) 0.88
Simultaneous determination of biogenic monoamines in rat brain dialysates using capillary high-performance liquid chromatography with photoluminescence following electron transfer. Anal Chem (2006) 0.88
NMDA-receptor mediated efflux of N-acetylaspartate: physiological and/or pathological importance? Neurochem Int (2004) 0.88
Cyclopropane compatibility with oxidative carbocation formation: total synthesis of clavosolide A. Org Lett (2012) 0.88
How fluorous is poly(2,2-bis(trifluoromethyl)-4,5-difluoro-1,3-dioxide-co-tetrafluoroethylene) (Teflon AF)? J Am Chem Soc (2004) 0.88
Scanning electroporation of selected areas of adherent cell cultures. Anal Chem (2007) 0.87
Studies toward the unique pederin family member psymberin: structure-activity relationships, biochemical studies, and genetics identify the mode-of-action of psymberin. J Am Chem Soc (2012) 0.86
Common approaches to the control of multidrug-resistant organisms other than methicillin-resistant Staphylococcus aureus (MRSA). Infect Dis Clin North Am (2010) 0.86
Profiling the substrate specificity of protein kinases by on-bead screening of peptide libraries. Biochemistry (2013) 0.86
Carbon Fiber/Epoxy Composite Ring-disk Electrode: Fabrication, Characterization and Application to Electrochemical Detection in Capillary High Performance Liquid Chromatography. J Electroanal Chem (Lausanne) (2009) 0.86
Total synthesis of the protein phosphatase 2A inhibitor lactodehydrothyrsiferol. Angew Chem Int Ed Engl (2011) 0.86
Simultaneous maximization of cell permeabilization and viability in single-cell electroporation using an electrolyte-filled capillary. Anal Chem (2007) 0.86
Single-cell transfection by electroporation using an electrolyte/plasmid-filled capillary. Anal Chem (2009) 0.86
Epidemiology of vancomycin-resistant enterococci among patients on an adult stem cell transplant unit: observations from an active surveillance program. Infect Control Hosp Epidemiol (2008) 0.85
Total synthesis of neopeltolide and analogs. Tetrahedron (2010) 0.85
Generation of focused electric field patterns at dielectric surfaces. Anal Chem (2005) 0.85
Elucidation of the active conformation of cinchona alkaloid catalyst and chemical mechanism of alcoholysis of meso anhydrides. Proc Natl Acad Sci U S A (2010) 0.85
Electroosmotic sampling. Application to determination of ectopeptidase activity in organotypic hippocampal slice cultures. Anal Chem (2010) 0.85
Luminescence targeting and imaging using a nanoscale generation 3 dendrimer in an in vivo colorectal metastatic rat model. Nanomedicine (2010) 0.85
Synthesis of sulfur-containing heterocycles through oxidative carbon-hydrogen bond functionalization. Org Lett (2012) 0.85
Effect of an open tube in series with a packed capillary column on liquid chromatographic performance. The influence of particle diameter, temperature, and system pressure. J Chromatogr A (2008) 0.84
Optimization of post-column reactor radius in capillary high performance liquid chromatography Effect of chromatographic column diameter and particle diameter. J Chromatogr A (2006) 0.84
Integration of a precolumn fluorogenic reaction, separation, and detection of reduced glutathione. Anal Chem (2010) 0.84
Bimolecular Coupling Reactions through Oxidatively Generated Aromatic Cations: Scope and Stereocontrol. Tetrahedron (2013) 0.84
Numerical calculations of single-cell electroporation with an electrolyte-filled capillary. Biophys J (2007) 0.84
Impact of genital warts on health related quality of life in men and women in mainland China: a multicenter hospital-based cross-sectional study. BMC Public Health (2012) 0.83
Aromatic cations from oxidative carbon-hydrogen bond cleavage in bimolecular carbon-carbon bond forming reactions. J Org Chem (2012) 0.83
Demonstration of the weighted-incidence syndromic combination antibiogram: an empiric prescribing decision aid. Infect Control Hosp Epidemiol (2012) 0.83
Ribosomal protein S14 silencing inhibits growth of acute myeloid leukemia transformed from myelodysplastic syndromes via activating p53. Hematology (2013) 0.83
Use of tris(2,2'-bipyridine)osmium as a photoluminescence-following electron-transfer reagent for postcolumn detection in capillary high-performance liquid chromatography. Anal Chem (2006) 0.83
Total synthesis of pederin and analogues. Angew Chem Int Ed Engl (2010) 0.83