Published in Endocrinology on August 04, 2010
Common cellular and molecular mechanisms in obesity and drug addiction. Nat Rev Neurosci (2011) 1.93
Further developments in the neurobiology of food and addiction: update on the state of the science. Nutrition (2012) 1.62
Influence of pre- and peri-natal nutrition on skeletal acquisition and maintenance. Bone (2011) 1.45
Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet. PLoS One (2010) 1.41
Developmental programming in response to maternal overnutrition. Front Genet (2011) 1.38
Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain. Neuropsychopharmacology (2011) 1.34
Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery. Proc Natl Acad Sci U S A (2013) 1.28
Minireview: Epigenetic programming of diabetes and obesity: animal models. Endocrinology (2012) 1.27
Maternal "junk-food" feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring. FASEB J (2011) 1.22
Early life nutrition, epigenetics and programming of later life disease. Nutrients (2014) 1.18
Natural rewards, neuroplasticity, and non-drug addictions. Neuropharmacology (2011) 1.16
What obesity research tells us about epigenetic mechanisms. Philos Trans R Soc Lond B Biol Sci (2013) 1.11
Gene-environment interactions controlling energy and glucose homeostasis and the developmental origins of obesity. Physiol Rev (2015) 1.10
Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet. Genes Nutr (2012) 1.09
Sucralose, a synthetic organochlorine sweetener: overview of biological issues. J Toxicol Environ Health B Crit Rev (2013) 1.06
Methamphetamine downregulates striatal glutamate receptors via diverse epigenetic mechanisms. Biol Psychiatry (2013) 1.04
Nutrition, epigenetics, and metabolic syndrome. Antioxid Redox Signal (2012) 1.04
Genetic and epigenetic control of metabolic health. Mol Metab (2013) 1.03
Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem (2012) 1.03
Issues in the timing of integrated early interventions: contributions from nutrition, neuroscience, and psychological research. Ann N Y Acad Sci (2013) 1.01
Direct bisulfite sequencing for examination of DNA methylation with gene and nucleotide resolution from brain tissues. Curr Protoc Neurosci (2012) 1.00
Early life programming as a target for prevention of child and adolescent mental disorders. BMC Med (2014) 1.00
Epigenomics, gestational programming and risk of metabolic syndrome. Int J Obes (Lond) (2015) 0.99
Animal models of in utero exposure to a high fat diet: a review. Biochim Biophys Acta (2013) 0.97
Modulation of taste responsiveness and food preference by obesity and weight loss. Physiol Behav (2012) 0.97
Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice. Diabetologia (2014) 0.96
Maternal high fat diet consumption during the perinatal period programs offspring behavior. Physiol Behav (2012) 0.96
Epigenetic dysregulation of the dopamine system in diet-induced obesity. J Neurochem (2012) 0.95
Prenatal maternal depression symptoms and nutrition, and child cognitive function. Br J Psychiatry (2013) 0.94
Insufficient maintenance DNA methylation is associated with abnormal embryonic development. BMC Med (2012) 0.94
Redefining the impact of nutrition on breast cancer incidence: is epigenetics involved? Nutr Res Rev (2012) 0.93
DNA hypomethylation of inflammation-associated genes in adipose tissue of female mice after multigenerational high fat diet feeding. Int J Obes (Lond) (2013) 0.93
Developmental programming of brain and behavior by perinatal diet: focus on inflammatory mechanisms. Dialogues Clin Neurosci (2014) 0.93
DNA methylation of SPARC and chronic low back pain. Mol Pain (2011) 0.93
Litter gender composition and sex affect maternal behavior and DNA methylation levels of the oprm1 gene in rat offspring. Front Psychiatry (2011) 0.92
Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain. Mol Pain (2014) 0.91
Maternal high-fat diet programming of the neuroendocrine system and behavior. Horm Behav (2015) 0.91
Rationale for further medical and health research on high-potency sweeteners. Chem Senses (2012) 0.91
Early origins of adult disease: approaches for investigating the programmable epigenome in humans, nonhuman primates, and rodents. ILAR J (2012) 0.89
Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology. PLoS One (2013) 0.89
Early postnatal nutrition determines adult physical activity and energy expenditure in female mice. Diabetes (2013) 0.89
Developmental changes in embryonic hypothalamic neurons during prenatal fat exposure. Am J Physiol Endocrinol Metab (2012) 0.87
Effects of perinatal exposure to palatable diets on body weight and sensitivity to drugs of abuse in rats. Physiol Behav (2012) 0.87
Food policies for physical and mental health. BMC Psychiatry (2014) 0.87
Maternal pre-pregnancy body mass index and offspring temperament and behavior at 1 and 2 years of age. Child Psychiatry Hum Dev (2013) 0.86
The role of maternal obesity in the risk of neuropsychiatric disorders. Front Neurosci (2015) 0.85
Early postweaning exercise improves central leptin sensitivity in offspring of rat dams fed high-fat diet during pregnancy and lactation. Am J Physiol Regul Integr Comp Physiol (2013) 0.85
Early Life Nutrition and Energy Balance Disorders in Offspring in Later Life. Nutrients (2015) 0.84
Epigenetic mechanisms in the development of behavior: advances, challenges, and future promises of a new field. Dev Psychopathol (2013) 0.84
Unraveling the mechanisms responsible for the comorbidity between metabolic syndrome and mental health disorders. Neuroendocrinology (2013) 0.83
Neuro-Genetics of Reward Deficiency Syndrome (RDS) as the Root Cause of "Addiction Transfer": A New Phenomenon Common after Bariatric Surgery. J Genet Syndr Gene Ther (2011) 0.83
Obesity at conception programs the opioid system in the offspring brain. Neuropsychopharmacology (2013) 0.82
Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus. Hum Mol Genet (2013) 0.82
Preterm birth and its long-term effects: methylation to mechanisms. Biology (Basel) (2014) 0.82
Redox Regulation and the Autistic Spectrum: Role of Tryptophan Catabolites, Immuno-inflammation, Autoimmunity and the Amygdala. Curr Neuropharmacol (2014) 0.81
Developmental programming of hypothalamic neuronal circuits: impact on energy balance control. Front Neurosci (2015) 0.81
Feed your head: neurodevelopmental control of feeding and metabolism. Annu Rev Physiol (2013) 0.81
Dietary intervention rescues maternal obesity induced behavior deficits and neuroinflammation in offspring. J Neuroinflammation (2014) 0.81
Nutritional models of foetal programming and nutrigenomic and epigenomic dysregulations of fatty acid metabolism in the liver and heart. Pflugers Arch (2013) 0.81
Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction? Front Neurosci (2015) 0.81
Ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice. J Clin Biochem Nutr (2011) 0.81
Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood. Nutrients (2015) 0.81
Reversal of dopamine system dysfunction in response to high-fat diet. Obesity (Silver Spring) (2013) 0.80
The Role of DNA Methylation in Cardiovascular Risk and Disease: Methodological Aspects, Study Design, and Data Analysis for Epidemiological Studies. Circ Res (2016) 0.80
Litter and sex effects on maternal behavior and DNA methylation of the Nr3c1 exon 17 promoter gene in hippocampus and cerebellum. Int J Dev Neurosci (2014) 0.79
Stimulation of nicotine reward and central cholinergic activity in Sprague-Dawley rats exposed perinatally to a fat-rich diet. Psychopharmacology (Berl) (2013) 0.79
Dissociable deficits of executive function caused by gestational adversity are linked to specific transcriptional changes in the prefrontal cortex. Neuropsychopharmacology (2014) 0.79
Maternal Body Mass Index during Pregnancy and Offspring Neurocognitive Development. Obstet Med (2013) 0.79
PGC1α -1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals. PPAR Res (2014) 0.78
Prenatal fat exposure and hypothalamic PPAR β/δ: Possible relationship to increased neurogenesis of orexigenic peptide neurons. Peptides (2016) 0.78
Evidence from clinical and animal model studies of the long-term and transgenerational impact of stress on DNA methylation. Semin Cell Dev Biol (2015) 0.78
Prenatal exposure to dietary fat induces changes in the transcriptional factors, TEF and YAP, which may stimulate differentiation of peptide neurons in rat hypothalamus. PLoS One (2013) 0.78
Maternal high-fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring. Obesity (Silver Spring) (2015) 0.78
Epigenetic programming of reward function in offspring: a role for maternal diet. Mamm Genome (2013) 0.78
Post-weaning diet affects faecal microbial composition but not selected adipose gene expression in the cat (Felis catus). PLoS One (2013) 0.78
Modeling dietary influences on offspring metabolic programming in Drosophila melanogaster. Reproduction (2016) 0.78
Nutritional Influence on Epigenetic Marks and Effect on Livestock Production. Front Genet (2016) 0.78
Early-Life Nutritional Programming of Cognition-The Fundamental Role of Epigenetic Mechanisms in Mediating the Relation between Early-Life Environment and Learning and Memory Process. Adv Nutr (2017) 0.77
Ubiquinol decreases monocytic expression and DNA methylation of the pro-inflammatory chemokine ligand 2 gene in humans. BMC Res Notes (2012) 0.77
An assessment of molecular pathways of obesity susceptible to nutrient, toxicant and genetically induced epigenetic perturbation. J Nutr Biochem (2015) 0.77
Maternal high-fat diet during pregnancy and lactation reduces the appetitive behavioral component in female offspring tested in a brief-access taste procedure. Am J Physiol Regul Integr Comp Physiol (2014) 0.77
Dietary methyl content regulates opioid responses in mice. J Pain Res (2013) 0.77
Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis. J Neurosci (2014) 0.76
GCN2 in the brain programs PPARγ2 and triglyceride storage in the liver during perinatal development in response to maternal dietary fat. PLoS One (2013) 0.76
A grand challenge for nutrigenomics. Front Genet (2010) 0.76
Maternal Obesity and Neurodevelopmental and Psychiatric Disorders in Offspring. Prenat Diagn (2016) 0.76
Regulation of the orexigenic neuropeptide, enkephalin, by PPARδ and fatty acids in neurons of the hypothalamus and forebrain. J Neurochem (2015) 0.76
Consumption habits of pregnant women and implications for developmental biology: a survey of predominantly Hispanic women in California. Nutr J (2013) 0.76
Food reinforcement during infancy. Prev Med (2016) 0.76
Influences of gestational obesity on associations between genotypes and gene expression levels in offspring following maternal gastrointestinal bypass surgery for obesity. PLoS One (2015) 0.76
Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 2. Sex-specific neuromolecular effects in the brain. Mol Cell Endocrinol (2015) 0.76
Environmentally induced epigenetic toxicity: potential public health concerns. Crit Rev Toxicol (2016) 0.76
Understanding the control of ingestive behavior in primates. Horm Behav (2014) 0.76
Drosophila melanogaster: An emerging model of transgenerational effects of maternal obesity. Mol Cell Endocrinol (2015) 0.76
Skeletal Muscle PGC1α -1 Nucleosome Position and -260nt DNA Methylation Determine Exercise Response and Prevent Ectopic Lipid Accumulation in Men. Endocrinology (2017) 0.76
Consumption of Substances of Abuse during Pregnancy Increases Consumption in Offspring: Possible Underlying Mechanisms. Front Nutr (2016) 0.75
Nicotine and ethanol co-use in Long-Evans rats: Stimulatory effects of perinatal exposure to a fat-rich diet. Alcohol (2015) 0.75
High-fat diet alters the dopamine and opioid systems: effects across development. Int J Obes Suppl (2012) 0.75
Role of maternal vitamins in programming health and chronic disease. Nutr Rev (2016) 0.75
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet (2005) 15.37
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet (2006) 10.47
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet (2007) 9.47
Drug abuse: hedonic homeostatic dysregulation. Science (1997) 8.22
Addiction and the brain antireward system. Annu Rev Psychol (2008) 5.17
Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat Neurosci (2009) 4.53
DNA hypomethylation and human diseases. Biochim Biophys Acta (2006) 4.31
A maternal 'junk food' diet in pregnancy and lactation promotes an exacerbated taste for 'junk food' and a greater propensity for obesity in rat offspring. Br J Nutr (2007) 2.54
Reward processing by the opioid system in the brain. Physiol Rev (2009) 2.46
Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet. J Physiol (2008) 2.41
Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism. Endocrinology (2008) 2.15
Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J Neurosci (2008) 1.96
Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments. Neuroscience (1999) 1.86
Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life? Br J Nutr (2007) 1.85
DNA methylation in development and human disease. Mutat Res (2008) 1.74
Intake of high-fat food is selectively enhanced by mu opioid receptor stimulation within the nucleus accumbens. J Pharmacol Exp Ther (1998) 1.73
Fetal alcohol exposure and temporal vulnerability: effects of binge-like alcohol exposure on the developing rat hippocampus. Neurotoxicol Teratol (2003) 1.73
Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology (2009) 1.71
DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet (2009) 1.68
Hypothalamic dopamine and serotonin in the regulation of food intake. Nutrition (2000) 1.63
Imprinting evolution and the price of silence. Bioessays (2003) 1.58
Maternal macronutrient and energy intakes in pregnancy and offspring intake at 10 y: exploring parental comparisons and prenatal effects. Am J Clin Nutr (2010) 1.55
Opioids for hedonic experience and dopamine to get ready for it. Psychopharmacology (Berl) (2006) 1.52
Maternal obesity is necessary for programming effect of high-fat diet on offspring. Am J Physiol Regul Integr Comp Physiol (2009) 1.49
Hypomethylation: one side of a larger picture. Ann N Y Acad Sci (2003) 1.44
Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats. Physiol Genomics (2005) 1.43
Increased maternal nutrition alters development of the appetite-regulating network in the brain. FASEB J (2006) 1.42
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring. PLoS One (2008) 1.32
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Mol Cell Biol (2007) 1.25
Established maternal obesity in the rat reprograms hypothalamic appetite regulators and leptin signaling at birth. Int J Obes (Lond) (2008) 1.24
Hypothalamic neuroendocrine circuitry is programmed by maternal obesity: interaction with postnatal nutritional environment. PLoS One (2009) 1.23
Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor. J Cell Mol Med (2008) 1.21
Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus. J Neurosci (2003) 1.20
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction. Am J Physiol Regul Integr Comp Physiol (2009) 1.18
Functional hyperdopaminergia in dopamine transporter knock-out mice. Biol Psychiatry (1999) 1.15
Endocrine and gene expression changes following forced swim stress exposure during cocaine abstinence in mice. Psychopharmacology (Berl) (2008) 1.14
Hypothalamic alterations in fetuses of high fat diet-fed obese female rats. J Endocrinol (2008) 1.14
Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling. Neuroscience (2009) 1.14
Overconsumption of dietary fat and alcohol: mechanisms involving lipids and hypothalamic peptides. Physiol Behav (2007) 1.13
Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus Relat Syst (2005) 1.11
Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving. J Psychiatr Res (2008) 1.10
Early life protein restriction alters dopamine circuitry. Neuroscience (2010) 1.04
Maternal high fat diet during the perinatal period alters mesocorticolimbic dopamine in the adult rat offspring: reduction in the behavioral responses to repeated amphetamine administration. Psychopharmacology (Berl) (2007) 1.02
Epigenetic dysregulation of dopaminergic genes in eating disorders. Int J Eat Disord (2010) 0.99
Differential responses of orexigenic neuropeptides to fasting in offspring of obese mothers. Obesity (Silver Spring) (2009) 0.93
Estrogen increases the taste threshold for sucrose in rats. Physiol Behav (2005) 0.92
Ovarian steroids alter mu opioid receptor trafficking in hippocampal parvalbumin GABAergic interneurons. Exp Neurol (2009) 0.92
Hormones that increase maternal responsiveness affect accumbal dopaminergic responses to pup- and food-stimuli in the female rat. Horm Behav (2009) 0.91
Effects of estradiol on food intake and meal patterns for diets that differ in flavor and fat content. Physiol Behav (2010) 0.88
Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens. Brain Res (2009) 0.87
Interaction between endogenous opioids and dopamine within the nucleus accumbens. Ann N Y Acad Sci (1992) 0.85
Meal size and number: relationship to dopamine levels in the ventromedial hypothalamic nucleus. Am J Physiol (1997) 0.85
Epigenetic control of the expression of opioid receptor genes. Epigenetics (2008) 0.80
Prepro-orexin and feeding-related peptide receptor expression in dehydration-induced anorexia. Regul Pept (2010) 0.78
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron (2004) 5.71
Early life programming and neurodevelopmental disorders. Biol Psychiatry (2010) 2.93
Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron (2010) 2.24
Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nat Med (2012) 2.13
Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain. Neuropsychopharmacology (2011) 1.34
Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity. Wiley Interdiscip Rev Syst Biol Med (2010) 1.27
Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the rat. J Pharmacol Exp Ther (2003) 1.01
Epigenetic dysregulation of the dopamine system in diet-induced obesity. J Neurochem (2012) 0.95
Gestational overgrowth and undergrowth affect neurodevelopment: similarities and differences from behavior to epigenetics. Int J Dev Neurosci (2012) 0.91
Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology. PLoS One (2013) 0.89
Central blockade of melanocortin receptors attenuates the metabolic and locomotor responses to peripheral interleukin-1beta administration. Neuropharmacology (2007) 0.81
Reversal of dopamine system dysfunction in response to high-fat diet. Obesity (Silver Spring) (2013) 0.80
Epigenetic programming of reward function in offspring: a role for maternal diet. Mamm Genome (2013) 0.78
In Vitro Characteristics of Porcine Tendon Hydrogel for Tendon Regeneration. Ann Plast Surg (2016) 0.75