David M Koelle

Author PubWeight™ 75.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nat Med 2009 4.03
2 Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation. J Exp Med 2007 3.66
3 Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials. Lancet 2012 2.54
4 Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J Clin Oncol 2011 2.52
5 Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection. Nature 2013 2.38
6 Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus Type 2 infection. J Infect Dis 2007 2.33
7 Autoreactive T cells in healthy individuals. J Immunol 2004 2.29
8 High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy. J Infect Dis 2001 1.85
9 A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J Exp Med 2003 1.72
10 Protective HIV-specific CD8+ T cells evade Treg cell suppression. Nat Med 2011 1.66
11 Repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule: effects on HIV-1 susceptibility. J Infect Dis 2006 1.62
12 Vascular E-selectin expression correlates with CD8 lymphocyte infiltration and improved outcome in Merkel cell carcinoma. J Invest Dermatol 2013 1.58
13 Herpes simplex virus infection of human dendritic cells induces apoptosis and allows cross-presentation via uninfected dendritic cells. J Immunol 2005 1.53
14 Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodes. Proc Natl Acad Sci U S A 2010 1.49
15 Diversity of the CD8+ T-cell response to herpes simplex virus type 2 proteins among persons with genital herpes. J Virol 2006 1.43
16 Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood. Clin Cancer Res 2011 1.36
17 T cell immunity to herpes simplex viruses in seronegative subjects: silent infection or acquired immunity? J Immunol 2003 1.29
18 HSV-2: in pursuit of a vaccine. J Clin Invest 2011 1.29
19 An extremely diverse CD4 response to vaccinia virus in humans is revealed by proteome-wide T-cell profiling. J Virol 2008 1.27
20 Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markers. Clin Cancer Res 2013 1.22
21 Cross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine. J Clin Invest 2012 1.16
22 Diversity in the acute CD8 T cell response to vaccinia virus in humans. J Immunol 2005 1.16
23 Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One 2011 1.16
24 Phase I study of a herpes simplex virus type 2 (HSV-2) DNA vaccine administered to healthy, HSV-2-seronegative adults by a needle-free injection system. Clin Vaccine Immunol 2008 1.12
25 Fulminant, acyclovir-resistant, herpes simplex virus type 2 hepatitis in an immunocompetent woman. J Clin Microbiol 2006 1.07
26 Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens. Future Microbiol 2010 1.07
27 Evasion of the mucosal innate immune system by herpes simplex virus type 2. J Virol 2009 1.05
28 Local CD4 and CD8 T-cell reactivity to HSV-1 antigens documents broad viral protein expression and immune competence in latently infected human trigeminal ganglia. PLoS Pathog 2013 1.01
29 Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes. J Clin Immunol 2010 1.01
30 Dominance and diversity in the primary human CD4 T cell response to replication-competent vaccinia virus. J Immunol 2007 1.00
31 Expression of cutaneous lymphocyte-associated antigen and E-selectin ligand by circulating human memory CD4+ T lymphocytes specific for herpes simplex virus type 2. J Infect Dis 2004 1.00
32 One-day regimen of valacyclovir for treatment of recurrent genital herpes simplex virus 2 infection. Sex Transm Dis 2008 0.98
33 T-cell immunity to human alphaherpesviruses. Curr Opin Virol 2013 0.98
34 Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays. J Control Release 2010 0.97
35 DNA vaccine delivery by densely-packed and short microprojection arrays to skin protects against vaginal HSV-2 challenge. Vaccine 2010 0.96
36 Reduced levels of neutralizing antibodies to Kaposi sarcoma-associated herpesvirus in persons with a history of Kaposi sarcoma. J Infect Dis 2004 0.96
37 Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection. J Gen Virol 2009 0.95
38 Virologic and immunologic evidence of multifocal genital herpes simplex virus 2 infection. J Virol 2014 0.95
39 An effector phenotype of CD8+ T cells at the junction epithelium during clinical quiescence of herpes simplex virus 2 infection. J Virol 2012 0.94
40 Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons. Vaccine 2011 0.94
41 HHV-8 infection: a model for reactivation and transmission. Rev Med Virol 2002 0.93
42 ORFeome approach to the clonal, HLA allele-specific CD4 T-cell response to a complex pathogen in humans. J Immunol Methods 2009 0.91
43 Longitudinal analysis of herpes simplex virus-specific CD4+ cell clonotypes in infected tissues and blood. J Infect Dis 2005 0.91
44 Vaxfectin-adjuvanted plasmid DNA vaccine improves protection and immunogenicity in a murine model of genital herpes infection. J Gen Virol 2012 0.89
45 Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials. J Clin Microbiol 2010 0.88
46 CD4 T-cell memory responses to viral infections of humans show pronounced immunodominance independent of duration or viral persistence. J Virol 2012 0.87
47 Public TCR use by herpes simplex virus-2-specific human CD8 CTLs. J Immunol 2010 0.87
48 A novel DNA vaccine technology conveying protection against a lethal herpes simplex viral challenge in mice. PLoS One 2013 0.86
49 Sequence-based methods for identifying epidemiologically linked herpes simplex virus type 2 strains. J Clin Microbiol 2006 0.85
50 Cellular immunity in monozygotic twins discordant for chronic fatigue syndrome. J Infect Dis 2002 0.84
51 Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes. J Virol 2012 0.83
52 Immunobiology of herpes simplex virus and cytomegalovirus infections of the fetus and newborn. Curr Immunol Rev 2010 0.83
53 Human CD4+ CD25 high cells suppress proliferative memory lymphocyte responses to herpes simplex virus type 2. J Virol 2006 0.82
54 Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2. Arch Virol 2008 0.82
55 A case of Ramsay Hunt-like syndrome caused by herpes simplex virus type 2. Clin Infect Dis 2005 0.80
56 Reduction of herpes simplex virus type-2 replication in cell cultures and in rodent models with peptide-conjugated morpholino oligomers. Antivir Ther 2010 0.79
57 Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system. Hum Vaccin Immunother 2014 0.78
58 Persistence of herpes simplex virus type 2 VP16-specific CD4+ T cells. Hum Immunol 2005 0.77
59 The murine intravaginal HSV-2 challenge model for investigation of DNA vaccines. Methods Mol Biol 2014 0.76
60 Doctor, why is my herpes so bad? The search continues. J Infect Dis 2008 0.76
61 T-Cell Responses to HSV-1 in Persons Who Have Survived Childhood Herpes Simplex Encephalitis. Pediatr Infect Dis J 2017 0.75