Published in EMBO Rep on August 13, 2010
TGFβ signalling in context. Nat Rev Mol Cell Biol (2012) 8.08
The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat Med (2013) 3.96
Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene (2012) 3.83
To differentiate or not--routes towards metastasis. Nat Rev Cancer (2012) 3.59
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell (2011) 2.49
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci U S A (2011) 2.45
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J (2011) 2.29
Tumor cell dissemination: emerging biological insights from animal models and cancer patients. Cancer Cell (2013) 2.08
Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res (2012) 2.00
Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression. Trends Cell Biol (2015) 1.87
miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition. Cell Death Differ (2011) 1.77
MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1. Nat Commun (2013) 1.76
Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer. J Biol Chem (2012) 1.72
Initial steps of metastasis: cell invasion and endothelial transmigration. Mutat Res (2011) 1.67
Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells. Cancers (Basel) (2013) 1.65
MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination. Proc Natl Acad Sci U S A (2013) 1.60
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol Med (2013) 1.59
Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res (2013) 1.54
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer. Nat Cell Biol (2017) 1.52
Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2. Cancer Res (2012) 1.50
MiR-200, a new star miRNA in human cancer. Cancer Lett (2013) 1.50
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530). Cell Death Dis (2013) 1.49
Analysis of microRNA-target interactions across diverse cancer types. Nat Struct Mol Biol (2013) 1.41
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition. PLoS One (2012) 1.41
A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors. Cancer Res (2011) 1.33
The metastatic niche and stromal progression. Cancer Metastasis Rev (2012) 1.30
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. J Clin Invest (2012) 1.29
MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition. Oncogene (2013) 1.29
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas. EMBO Mol Med (2011) 1.28
Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2. Cancer Res (2013) 1.27
Expanding roles of ZEB factors in tumorigenesis and tumor progression. Am J Cancer Res (2011) 1.26
Epithelial mesenchymal transition in drug resistance and metastasis of lung cancer. Cancer Res Treat (2012) 1.24
Functions of lncRNA HOTAIR in lung cancer. J Hematol Oncol (2014) 1.23
MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma. PLoS One (2011) 1.23
ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. J Clin Invest (2014) 1.22
The Regulatory Role of MicroRNAs in EMT and Cancer. J Oncol (2015) 1.22
ZEB2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma. PLoS One (2012) 1.21
MicroRNA Regulation of SIRT1. Front Physiol (2012) 1.21
MiR-200c and HuR in ovarian cancer. BMC Cancer (2013) 1.18
Transcriptional activation of ZEB1 by Slug leads to cooperative regulation of the epithelial-mesenchymal transition-like phenotype in melanoma. J Invest Dermatol (2011) 1.17
Downregulation of endothelial microRNA-200b supports cutaneous wound angiogenesis by desilencing GATA binding protein 2 and vascular endothelial growth factor receptor 2. Arterioscler Thromb Vasc Biol (2012) 1.17
miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1. Biochem Res Int (2013) 1.16
MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells. BMC Cancer (2013) 1.16
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis. Front Oncol (2015) 1.15
Epithelial-mesenchymal transition in breast cancer progression and metastasis. Chin J Cancer (2011) 1.14
Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives. Cancer Manag Res (2014) 1.13
Coupled reversible and irreversible bistable switches underlying TGFβ-induced epithelial to mesenchymal transition. Biophys J (2013) 1.12
IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation. Mol Cancer (2012) 1.12
Endometrial miR-200c is altered during transformation into cancerous states and targets the expression of ZEBs, VEGFA, FLT1, IKKβ, KLF9, and FBLN5. Reprod Sci (2012) 1.11
A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation. J Neurosci (2012) 1.10
Oxidative stress and microRNAs in vascular diseases. Int J Mol Sci (2013) 1.10
MicroRNA-200 family modulation in distinct breast cancer phenotypes. PLoS One (2012) 1.10
A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster. Mol Cell Biol (2013) 1.10
Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression. Cell Death Dis (2013) 1.07
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer. J Biol Chem (2013) 1.07
Epithelial-mesenchymal transition in ovarian carcinoma. Front Oncol (2012) 1.07
Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT). J Biol Chem (2012) 1.06
The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors. Cancer Res (2014) 1.06
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors. Cell Mol Life Sci (2012) 1.06
Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J Cell Biol (2013) 1.06
Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer. Mol Ther (2014) 1.05
What is bad in cancer is good in the embryo: importance of EMT in neural crest development. Semin Cell Dev Biol (2012) 1.05
Cell adhesion and its endocytic regulation in cell migration during neural development and cancer metastasis. Int J Mol Sci (2012) 1.04
LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway. Oncotarget (2016) 1.03
Epithelial-mesenchymal transition and senescence: two cancer-related processes are crossing paths. Aging (Albany NY) (2010) 1.03
Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor. Dev Cell (2014) 1.03
Copy number variants in candidate genes are genetic modifiers of Hirschsprung disease. PLoS One (2011) 1.02
MicroRNA Control of Invasion and Metastasis Pathways. Front Genet (2011) 1.02
MicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasis. Carcinogenesis (2014) 1.02
Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. Genome Biol (2014) 1.02
Pro-inflammatory role of microrna-200 in vascular smooth muscle cells from diabetic mice. Arterioscler Thromb Vasc Biol (2012) 1.02
miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development. Development (2014) 1.01
The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. Oncogene (2015) 1.01
MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells. Oncotarget (2014) 1.01
Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions. Drug Resist Updat (2011) 1.01
ANTXR1, a stem cell-enriched functional biomarker, connects collagen signaling to cancer stem-like cells and metastasis in breast cancer. Cancer Res (2013) 1.00
A comparison of epithelial-to-mesenchymal transition and re-epithelialization. Semin Cancer Biol (2012) 1.00
Tumor Budding: The Name is EMT. Partial EMT. J Clin Med (2016) 1.00
An integrated expression profiling reveals target genes of TGF-β and TNF-α possibly mediated by microRNAs in lung cancer cells. PLoS One (2013) 1.00
Stability of the hybrid epithelial/mesenchymal phenotype. Oncotarget (2016) 0.99
Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin. Thyroid Res (2011) 0.99
Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. Int J Cancer (2013) 0.99
Mitochondria and Oxidative Stress in the Cardiorenal Metabolic Syndrome. Cardiorenal Med (2012) 0.98
Tumor suppressive microRNA‑138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. Int J Oncol (2012) 0.98
Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancers. Ann Transl Med (2014) 0.97
MicroRNAs in lung cancer. World J Methodol (2014) 0.97
Knockdown of BAG3 induces epithelial-mesenchymal transition in thyroid cancer cells through ZEB1 activation. Cell Death Dis (2014) 0.97
MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance. PLoS One (2014) 0.97
Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1. Cancer Biol Ther (2014) 0.96
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene (2015) 0.94
A novel MCF-10A line allowing conditional oncogene expression in 3D culture. Cell Commun Signal (2011) 0.94
Inferring microRNA and transcription factor regulatory networks in heterogeneous data. BMC Bioinformatics (2013) 0.93
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med (2015) 0.93
Signaling pathways in cell polarity. Cold Spring Harb Perspect Biol (2012) 0.92
p53 Spreads out further: suppression of EMT and stemness by activating miR-200c expression. Cell Res (2011) 0.92
MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis. Oncotarget (2015) 0.92
MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis. J Biol Chem (2014) 0.92
ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma. Genes Cancer (2013) 0.91
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling. Nat Commun (2015) 0.91
Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo. Sci Rep (2013) 0.91
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer (2006) 46.47
The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
The basics of epithelial-mesenchymal transition. J Clin Invest (2009) 32.82
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol (2008) 24.27
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer (2007) 18.69
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet (2008) 17.67
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev (2008) 15.01
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep (2008) 10.71
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem (2008) 10.08
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell (2001) 10.02
Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat Rev Cancer (2005) 9.04
Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One (2008) 8.97
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol (2009) 8.63
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell (2009) 8.33
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A (2001) 7.99
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45
A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. Cancer Cell (2009) 6.23
Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell (2008) 5.88
MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res (2008) 5.54
Snail blocks the cell cycle and confers resistance to cell death. Genes Dev (2004) 5.34
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology (2008) 5.28
The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene (2007) 4.90
MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle (2008) 4.81
Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. Cancer Res (2007) 4.65
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res (2009) 4.24
Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res (2009) 4.19
Development and characterization of gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol (2007) 4.12
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res (2008) 4.04
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. Am J Pathol (2002) 3.82
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology (2006) 3.68
Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle (2009) 3.68
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev (2009) 3.58
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res (2009) 3.57
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer (2005) 3.26
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Res (2006) 3.21
MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells (2008) 3.14
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin. Cells Tissues Organs (2005) 3.10
miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res (2009) 3.07
Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol Med (2009) 3.05
miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One (2009) 2.97
The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci (2009) 2.95
Multiple tumor suppressor pathways negatively regulate telomerase. Cell (2003) 2.82
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J (2003) 2.67
Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells. Cancer Res (2008) 2.67
miR-200b mediates post-transcriptional repression of ZFHX1B. RNA (2007) 2.67
Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development (2008) 2.55
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res (2006) 2.47
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev (2009) 2.41
Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K. Cell (2009) 2.39
The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers. Cancer Res (2006) 2.38
MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal (2009) 2.38
Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells. Clin Cancer Res (2009) 2.28
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer. Gynecol Oncol (2009) 2.26
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1. Oncogene (2010) 2.25
Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis. Oncogene (2007) 2.12
Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition. Mol Cancer Ther (2007) 2.07
MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. Clin Chem (2010) 1.95
Collagen type I-induced Smad-interacting protein 1 expression downregulates E-cadherin in pancreatic cancer. Oncogene (2006) 1.89
Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition. Gynecol Oncol (2009) 1.84
Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers. J Oncol (2009) 1.84
miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer. Oncogene (2010) 1.82
E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells. Int J Cancer (2010) 1.78
The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc Natl Acad Sci U S A (2008) 1.76
miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1. Mol Cell (2010) 1.76
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. Am J Pathol (2001) 1.73
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Mol Biol Cell (2007) 1.71
miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion. Biochem Biophys Res Commun (2009) 1.61
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biol Ther (2009) 1.61
microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network. Carcinogenesis (2010) 1.59
SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer. Proc Natl Acad Sci U S A (2009) 1.56
Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors. Cancer Res (2010) 1.52
The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion. J Biol Chem (2009) 1.49
ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease. Mod Pathol (2008) 1.32
Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin. J Thorac Oncol (2008) 1.28
Delta-crystallin enhancer binding factor 1 controls the epithelial to mesenchymal transition phenotype and resistance to the epidermal growth factor receptor inhibitor erlotinib in human head and neck squamous cell carcinoma lines. Clin Cancer Res (2009) 1.25
ZEB proteins link cell motility with cell cycle control and cell survival in cancer. Cell Cycle (2010) 1.23
deltaEF1 and SIP1 are differentially expressed and have overlapping activities during Xenopus embryogenesis. Dev Dyn (2006) 1.16
BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1. Cell Res (2009) 1.16
Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells. Breast Cancer Res Treat (2009) 1.15
Expression of the ZEB1 (deltaEF1) transcription factor in human: additional insights. Mol Cell Biochem (2008) 1.15
Zeb1-mediated T-cadherin repression increases the invasive potential of gallbladder cancer. FEBS Lett (2008) 1.04
Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions. Clin Exp Metastasis (2010) 1.04
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep (2008) 10.71
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol (2009) 8.63
Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol (2007) 4.75
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res (2008) 4.04
E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev (2009) 3.95
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology (2006) 3.68
L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers. J Cell Biol (2005) 2.39
ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell (2006) 2.30
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J (2011) 2.29
A transcription factor-based mechanism for mouse heterochromatin formation. Nat Struct Mol Biol (2012) 2.15
Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. EMBO J (2003) 1.75
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol Med (2013) 1.59
Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer. Int J Cancer (2007) 1.48
Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis. Cancer Res (2007) 1.46
Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas. Int J Cancer (2004) 1.39
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression. FEBS Lett (2007) 1.36
Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice. Clin Cancer Res (2004) 1.28
Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer. Clin Gastroenterol Hepatol (2005) 1.27
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition. Cancer Lett (2012) 1.26
Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc Natl Acad Sci U S A (2012) 1.23
Beta-catenin up-regulates the expression of the urokinase plasminogen activator in human colorectal tumors. Cancer Res (2004) 1.17
MicroRNAs coordinately regulate protein complexes. BMC Syst Biol (2011) 1.17
Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells. J Cell Sci (2010) 1.15
beta-Catenin regulates the expression of tenascin-C in human colorectal tumors. Oncogene (2005) 1.10
A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster. Mol Cell Biol (2013) 1.10
Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b. Toxicol Sci (2011) 1.09
DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells. J Biol Chem (2004) 1.07
Zeb1 regulates E-cadherin and Epcam (epithelial cell adhesion molecule) expression to control cell behavior in early zebrafish development. J Biol Chem (2013) 1.01
Microarray versus conventional prediction of lymph node metastasis in colorectal carcinoma. Cancer (2005) 1.00
Invasion associated up-regulation of nuclear factor kappaB target genes in colorectal cancer. Cancer (2009) 0.99
Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions. Lab Invest (2003) 0.97
L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers. Mol Cancer Res (2010) 0.95
p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors. Gastroenterology (2008) 0.95
Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors. Cell Cycle (2012) 0.94
A human three-dimensional cell line model allows the study of dynamic and reversible epithelial-mesenchymal and mesenchymal-epithelial transition that underpins colorectal carcinogenesis. Cells Tissues Organs (2007) 0.93
p53 Spreads out further: suppression of EMT and stemness by activating miR-200c expression. Cell Res (2011) 0.92
Aberrant expression of TTF-1 and forkhead factor HFH-4 in atrophic gastritis and ciliated metaplasia suggests gastric broncho-pulmonary transdetermination. J Pathol (2005) 0.92
Variable FZD7 expression in colorectal cancers indicates regulation by the tumour microenvironment. Dev Dyn (2010) 0.91
Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells. Cancer Lett (2008) 0.91
MiR-34 and SNAIL: another double-negative feedback loop controlling cellular plasticity/EMT governed by p53. Cell Cycle (2012) 0.91
Molecular signature for lymphatic metastasis in colorectal carcinomas. Ann Surg (2008) 0.90
T-cell factor-4 frameshift mutations occur frequently in human microsatellite instability-high colorectal carcinomas but do not contribute to carcinogenesis. Cancer Res (2002) 0.89
Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma. J Gastroenterol Hepatol (2015) 0.89
Forced expression of deltaN-TCF-1B in colon cancer derived cell lines is accompanied by the induction of CEACAM5/6 and mesothelin. Cancer Lett (2005) 0.88
Stress-induced cleavage of Myc promotes cancer cell survival. Genes Dev (2014) 0.87
The miR-200 family: central player for gain and loss of the epithelial phenotype. Gastroenterology (2009) 0.87
ZEB1 in Pancreatic Cancer. Cancers (Basel) (2010) 0.86
Prognostic significance of microsatellite instability in curatively resected adenocarcinoma of the small intestine. Cancer Lett (2004) 0.85
Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia. J Pathol (2004) 0.84
Mycosis fungoides palmaris et plantaris--an unusual variant of cutaneous T-cell lymphoma. Eur J Dermatol (2006) 0.84
Frizzled7 dictates embryonic morphogenesis: implications for colorectal cancer progression. Front Biosci (2007) 0.83
Generation and characterization of human monoclonal scFv antibodies against Helicobacter pylori antigens. Infect Immun (2002) 0.82
Predictive molecular markers for colorectal cancer patients with resected liver metastasis and adjuvant chemotherapy. Gastroenterology (2007) 0.82
Wnt/FZD signaling and colorectal cancer morphogenesis. Front Biosci (2007) 0.82
Gastric PDX-1 expression in pancreatic metaplasia and endocrine cell hyperplasia in atrophic corpus gastritis. Mod Pathol (2004) 0.82
Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency. Stem Cell Res (2013) 0.81
ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition. Gastroenterology (2009) 0.81
The microenvironment controls CDX2 homeobox gene expression in colorectal cancer cells. Am J Pathol (2007) 0.81
Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability. Cancer Lett (2006) 0.80
Precancerous lesions upon sporadic activation of beta-catenin in mice. Gastroenterology (2007) 0.79
Under stress: p53 controls EMT and stemness in pancreatic epithelial cells. Cell Cycle (2011) 0.76
Native promoter reporters validate transcriptional targets. Methods Mol Biol (2008) 0.76