Published in PLoS Negl Trop Dis on August 10, 2010
Effects of short-course oral corticosteroid therapy in early dengue infection in Vietnamese patients: a randomized, placebo-controlled trial. Clin Infect Dis (2012) 3.06
Validation of an internally controlled one-step real-time multiplex RT-PCR assay for the detection and quantitation of dengue virus RNA in plasma. J Virol Methods (2011) 1.85
Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue. PLoS Negl Trop Dis (2011) 1.67
The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach. PLoS Negl Trop Dis (2011) 1.64
Cardiovascular manifestations of the emerging dengue pandemic. Nat Rev Cardiol (2014) 1.58
Lessons from malaria control to help meet the rising challenge of dengue. Lancet Infect Dis (2012) 1.54
Evaluation of the NS1 rapid test and the WHO dengue classification schemes for use as bedside diagnosis of acute dengue fever in adults. Am J Trop Med Hyg (2011) 1.52
The early clinical features of dengue in adults: challenges for early clinical diagnosis. PLoS Negl Trop Dis (2011) 1.52
A systematic screen of FDA-approved drugs for inhibitors of biological threat agents. PLoS One (2013) 1.38
A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients. J Infect Dis (2012) 1.37
Immunological and viral determinants of dengue severity in hospitalized adults in Ha Noi, Viet Nam. PLoS Negl Trop Dis (2011) 1.29
High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections. J Virol (2011) 1.14
Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials. PLoS Negl Trop Dis (2012) 1.05
Flaviviruses: braking the entering. Curr Opin Virol (2013) 1.02
Chloroquine use improves dengue-related symptoms. Mem Inst Oswaldo Cruz (2013) 1.01
Experimental therapies for yellow fever. Antiviral Res (2012) 0.96
Predicting outcome from dengue. BMC Med (2014) 0.95
Dengue therapeutics, chemoprophylaxis, and allied tools: state of the art and future directions. PLoS Negl Trop Dis (2014) 0.94
Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry. F1000Res (2015) 0.92
Review article: Research on dengue during World War II revisited. Am J Trop Med Hyg (2014) 0.91
Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity. Antiviral Res (2014) 0.90
Lovastatin for the Treatment of Adult Patients With Dengue: A Randomized, Double-Blind, Placebo-Controlled Trial. Clin Infect Dis (2015) 0.87
Lovastatin delays infection and increases survival rates in AG129 mice infected with dengue virus serotype 2. PLoS One (2014) 0.86
Synergistic suppression of dengue virus replication using a combination of nucleoside analogs and nucleoside synthesis inhibitors. Antimicrob Agents Chemother (2015) 0.85
Hydroxychloroquine-inhibited dengue virus is associated with host defense machinery. J Interferon Cytokine Res (2014) 0.84
The Role of Secretory Autophagy in Zika Virus Transfer through the Placental Barrier. Front Cell Infect Microbiol (2017) 0.83
Recent advances in understanding dengue. F1000Res (2016) 0.82
Discovery of Dengue Virus NS4B Inhibitors. J Virol (2015) 0.81
Within-host viral dynamics of dengue serotype 1 infection. J R Soc Interface (2014) 0.80
Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes. PLoS Negl Trop Dis (2014) 0.79
Myocarditis in a traveler returning from the Dominican Republic: an unusual presentation of dengue fever. Am J Trop Med Hyg (2014) 0.79
Lack of protection against ebola virus from chloroquine in mice and hamsters. Emerg Infect Dis (2015) 0.79
Dengue human infection models supporting drug development. J Infect Dis (2014) 0.79
Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model. J Gen Virol (2015) 0.78
Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection. PLoS Negl Trop Dis (2015) 0.78
Flaviviruses are sensitive to inhibition of thymidine synthesis pathways. J Virol (2013) 0.78
Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients. PLoS Negl Trop Dis (2016) 0.76
Chloroquine could be used for the treatment of filoviral infections and other viral infections that emerge or emerged from viruses requiring an acidic pH for infectivity. Cell Biochem Funct (2016) 0.75
Dengue: Moving from Current Standard of Care to State-of-the-Art Treatment. Curr Treat Options Infect Dis (2015) 0.75
Reply to Halstead and Sayce et al. Clin Infect Dis (2012) 0.75
Drivers of Inter-individual Variation in Dengue Viral Load Dynamics. PLoS Comput Biol (2016) 0.75
Dengue virus compartmentalization during antibody-enhanced infection. Sci Rep (2017) 0.75
Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models. Viruses (2016) 0.75
Therapeutic Potential of Spirooxindoles as Antiviral Agents. ACS Infect Dis (2016) 0.75
Current Status of Dengue Therapeutics Research and Development. J Infect Dis (2017) 0.75
Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases. Pharmacol Res Perspect (2017) 0.75
Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice. J Exp Med (2017) 0.75
Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond. Nat Rev Drug Discov (2017) 0.75
Blockade of dengue virus infection and viral cytotoxicity in neuronal cells in vitro and in vivo by targeting endocytic pathways. Sci Rep (2017) 0.75
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science (2004) 16.26
Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J Infect Dis (2000) 11.44
Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A (2004) 9.00
Structure of the dengue virus envelope protein after membrane fusion. Nature (2004) 7.97
High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever. J Infect Dis (2002) 4.69
Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections. J Clin Microbiol (2002) 4.63
Structure of the immature dengue virus at low pH primes proteolytic maturation. Science (2008) 3.86
Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization. J Infect Dis (2004) 3.81
Diagnostic accuracy of NS1 ELISA and lateral flow rapid tests for dengue sensitivity, specificity and relationship to viraemia and antibody responses. PLoS Negl Trop Dis (2009) 3.30
Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses. EMBO Rep (2003) 3.29
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A (2003) 2.91
Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever. J Infect Dis (2007) 2.89
The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infection. Pediatr Infect Dis J (2008) 2.50
Acidotropic amines inhibit proteolytic processing of flavivirus prM protein. Virology (1990) 2.34
Effects of chloroquine on viral infections: an old drug against today's diseases? Lancet Infect Dis (2003) 2.23
Strategies for development of Dengue virus inhibitors. Antiviral Res (2010) 2.11
Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion. J Virol (1999) 2.07
Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses. BMC Infect Dis (2010) 1.97
Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo. J Exp Med (2005) 1.50
Differential activation of human monocyte-derived and plasmacytoid dendritic cells by West Nile virus generated in different host cells. J Virol (2007) 1.48
A complex interplay among virus, dendritic cells, T cells, and cytokines in dengue virus infections. J Immunol (2008) 1.48
Immunology and immunopathogenesis of dengue disease. Adv Virus Res (2003) 1.41
Cytokines, PGE2 and endotoxic fever: a re-assessment. Prostaglandins Other Lipid Mediat (2005) 1.39
Performance of a commercial rapid dengue NS1 antigen immunochromatography test with reference to dengue NS1 antigen-capture ELISA. J Virol Methods (2008) 1.36
Confronting an influenza pandemic with inexpensive generic agents: can it be done? Lancet Infect Dis (2008) 1.35
Evaluation of dengue NS1 antigen detection tests with acute sera from patients infected with dengue virus in Venezuela. Diagn Microbiol Infect Dis (2009) 1.35
Chloroquine inhibits production of TNF-alpha, IL-1beta and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes. Rheumatology (Oxford) (2006) 1.28
On chikungunya acute infection and chloroquine treatment. Vector Borne Zoonotic Dis (2008) 1.24
Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria. Eur J Clin Pharmacol (2004) 1.19
Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanism. J Immunol (2000) 1.16
The medicinal chemistry of dengue fever. J Med Chem (2009) 1.08
Lack of a pharmacokinetic interaction between azithromycin and chloroquine. Am J Trop Med Hyg (2006) 1.07
CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9. J Biol Chem (2003) 1.04
Mode of action of hydroxychloroquine in RA-evidence of an inhibitory effect on toll-like receptor signaling. Nat Clin Pract Rheumatol (2006) 1.03
Long-term effectiveness of antimalarial drugs in rheumatic diseases. Ann Rheum Dis (1998) 1.01
A trial of Fansidar plus chloroquine or Fansidar alone for the treatment of uncomplicated malaria in Gambian children. Trans R Soc Trop Med Hyg (1998) 1.00
Optimal use of antimalarials in treating cutaneous lupus erythematosus. Am J Clin Dermatol (2005) 0.90
Antipyretic, parasitologic, and immunologic effects of combining sulfadoxine/pyrimethamine with chloroquine or paracetamol for treating uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg (2003) 0.89
Chloroquine decreases cell-surface expression of tumour necrosis factor receptors in human histiocytic U-937 cells. Immunology (2002) 0.89
Antimalarial drugs for rheumatoid arthritis. Am J Med (1983) 0.88
Sulfadoxine-pyrimethamine monotherapy in Tanzanian children gives rapid parasite clearance but slow fever clearance that is improved by chloroquine in combination therapy. Trop Med Int Health (2002) 0.87
Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med (2009) 33.25
The global distribution and burden of dengue. Nature (2013) 27.92
Oseltamivir resistance during treatment of influenza A (H5N1) infection. N Engl J Med (2005) 15.53
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med (2006) 14.21
Avian influenza A (H5N1) infection in humans. N Engl J Med (2005) 12.95
Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med (2014) 11.87
Avian influenza A (H5N1) in 10 patients in Vietnam. N Engl J Med (2004) 11.31
Dengue. N Engl J Med (2012) 10.45
Dengue: a continuing global threat. Nat Rev Microbiol (2010) 9.96
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet (2010) 8.52
Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. N Engl J Med (2005) 6.47
Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam. N Engl J Med (2002) 5.24
Evolutionary history of Salmonella typhi. Science (2006) 5.00
Intrahost modeling of artemisinin resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A (2010) 4.50
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
In vivo parasitological measures of artemisinin susceptibility. J Infect Dis (2010) 4.25
A study of typhoid fever in five Asian countries: disease burden and implications for controls. Bull World Health Organ (2008) 4.11
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathog (2008) 3.79
Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial. Lancet (2004) 3.72
The WHO dengue classification and case definitions: time for a reassessment. Lancet (2006) 3.69
Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med (2007) 3.63
Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis. N Engl J Med (2016) 3.59
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe (2010) 3.48
Diagnostic accuracy of NS1 ELISA and lateral flow rapid tests for dengue sensitivity, specificity and relationship to viraemia and antibody responses. PLoS Negl Trop Dis (2009) 3.30
Streptococcus suis meningitis in adults in Vietnam. Clin Infect Dis (2008) 3.18
In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam. Malar J (2012) 3.13
Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial. Lancet Infect Dis (2010) 3.08
Effects of short-course oral corticosteroid therapy in early dengue infection in Vietnamese patients: a randomized, placebo-controlled trial. Clin Infect Dis (2012) 3.06
The relationship between age and the manifestations of and mortality associated with severe malaria. Clin Infect Dis (2008) 3.05
Evaluation of diagnostic tests: dengue. Nat Rev Microbiol (2010) 2.91
Clinical features of human influenza A (H5N1) infection in Vietnam: 2004-2006. Clin Infect Dis (2009) 2.89
Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever. J Infect Dis (2007) 2.89
In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. Antimicrob Agents Chemother (2004) 2.77
Phylogenetic relationships and differential selection pressures among genotypes of dengue-2 virus. Virology (2002) 2.75
Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones. Antimicrob Agents Chemother (2007) 2.73
Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance. Malar J (2009) 2.70
Altitude Sickness in Climbers and Efficacy of NSAIDs Trial (ASCENT): randomized, controlled trial of ibuprofen versus placebo for prevention of altitude illness. Wilderness Environ Med (2012) 2.70
Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum. Antimicrob Agents Chemother (2010) 2.68
Clinical research in resource-limited settings: enhancing research capacity and working together to make trials less complicated. PLoS Negl Trop Dis (2010) 2.68
Multicentre prospective study on dengue classification in four South-east Asian and three Latin American countries. Trop Med Int Health (2011) 2.60
Into the eye of the cytokine storm. Microbiol Mol Biol Rev (2012) 2.58
Transparent development of the WHO rapid advice guidelines. PLoS Med (2007) 2.57
Gatifloxacin versus chloramphenicol for uncomplicated enteric fever: an open-label, randomised, controlled trial. Lancet Infect Dis (2011) 2.54
Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets. PLoS Med (2009) 2.47
Progress towards a dengue vaccine. Lancet Infect Dis (2009) 2.45
The influence of HIV infection on clinical presentation, response to treatment, and outcome in adults with Tuberculous meningitis. J Infect Dis (2005) 2.38
Guidelines for field surveys of the quality of medicines: a proposal. PLoS Med (2009) 2.36
Clinical diagnosis and assessment of severity of confirmed dengue infections in Vietnamese children: is the world health organization classification system helpful? Am J Trop Med Hyg (2004) 2.33
Multi-country evaluation of the sensitivity and specificity of two commercially-available NS1 ELISA assays for dengue diagnosis. PLoS Negl Trop Dis (2010) 2.33
Policy: An intergovernmental panel on antimicrobial resistance. Nature (2014) 2.22
Epidemiological factors associated with dengue shock syndrome and mortality in hospitalized dengue patients in Ho Chi Minh City, Vietnam. Am J Trop Med Hyg (2011) 2.17
Emergence of the Asian 1 genotype of dengue virus serotype 2 in viet nam: in vivo fitness advantage and lineage replacement in South-East Asia. PLoS Negl Trop Dis (2010) 2.17
High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia. J Clin Microbiol (2008) 2.14
Serologic survey of pandemic (H1N1) 2009 virus, Guangxi Province, China. Emerg Infect Dis (2009) 2.13
Liver involvement associated with dengue infection in adults in Vietnam. Am J Trop Med Hyg (2010) 2.10
Clinical characteristics of Dengue shock syndrome in Vietnamese children: a 10-year prospective study in a single hospital. Clin Infect Dis (2013) 2.08
Population-level antibody estimates to novel influenza A/H7N9. J Infect Dis (2013) 2.03
Usefulness and applicability of the revised dengue case classification by disease: multi-centre study in 18 countries. BMC Infect Dis (2011) 2.03
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. Nat Genet (2011) 2.00
Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness. PLoS Negl Trop Dis (2008) 1.99
Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses. BMC Infect Dis (2010) 1.97
Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome. J Immunol (2006) 1.92
Relationship between Mycobacterium tuberculosis genotype and the clinical phenotype of pulmonary and meningeal tuberculosis. J Clin Microbiol (2008) 1.89
Loop-mediated isothermal PCR (LAMP) for the diagnosis of falciparum malaria. Am J Trop Med Hyg (2007) 1.89
The pathogenesis of dengue. Vaccine (2011) 1.88
Maternal antibody and viral factors in the pathogenesis of dengue virus in infants. J Infect Dis (2007) 1.88
Endemic dengue associated with the co-circulation of multiple viral lineages and localized density-dependent transmission. PLoS Pathog (2011) 1.87
Fitness benefits in fluoroquinolone-resistant Salmonella Typhi in the absence of antimicrobial pressure. Elife (2013) 1.86
WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A (H5N1) virus. Lancet Infect Dis (2007) 1.85
Validation of an internally controlled one-step real-time multiplex RT-PCR assay for the detection and quantitation of dengue virus RNA in plasma. J Virol Methods (2011) 1.85
Host and viral features of human dengue cases shape the population of infected and infectious Aedes aegypti mosquitoes. Proc Natl Acad Sci U S A (2013) 1.84
A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation. BMC Infect Dis (2009) 1.83
A multi-center randomised controlled trial of gatifloxacin versus azithromycin for the treatment of uncomplicated typhoid fever in children and adults in Vietnam. PLoS One (2008) 1.83
Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement. PLoS Med (2012) 1.82
Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models. PLoS One (2010) 1.80
Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam. PLoS One (2009) 1.79
Evaluation of the MTBDRsl test for detection of second-line-drug resistance in Mycobacterium tuberculosis. J Clin Microbiol (2010) 1.78
Dengue in Vietnamese infants--results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity. J Infect Dis (2008) 1.78
Serial MRI to determine the effect of dexamethasone on the cerebral pathology of tuberculous meningitis: an observational study. Lancet Neurol (2007) 1.77
Infectious disease: tough choices to reduce Ebola transmission. Nature (2014) 1.77
Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of Citrobacter rodentium. Mol Microbiol (2003) 1.76