Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial.

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Published in Lancet on August 19, 2010


Yung-Jue Bang1, Eric Van Cutsem, Andrea Feyereislova, Hyun C Chung, Lin Shen, Akira Sawaki, Florian Lordick, Atsushi Ohtsu, Yasushi Omuro, Taroh Satoh, Giuseppe Aprile, Evgeny Kulikov, Julie Hill, Michaela Lehle, Josef Rüschoff, Yoon-Koo Kang, ToGA Trial Investigators

Author Affiliations

1: Seoul National University College of Medicine, Seoul, South Korea.

Associated clinical trials:

ToGA Study - A Study of Herceptin (Trastuzumab) in Combination With Chemotherapy Compared With Chemotherapy Alone in Patients With HER2-Positive Advanced Gastric Cancer | NCT01041404

Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC) (Her+XELOX) | NCT01396707

Trastuzumab Plus Docetaxel and Capecitabine For First Line Treatment of Her2-Positive Advanced Gastric Cancer | NCT02004769

A Clinicobiological Database in Metastatic Digestive Cancers (BCB-CBIO-DIG) | NCT03978078

Real-world Data (RWD) of Ramucirumab Plus Paclitaxel | NCT04915807

Evaluation of HER2-targeted Therapy for Gastric Cancer and Establishment and Verification of Monitoring System | NCT05165602

Cytoreductive Surgery Combined With HIPEC and Chemotherapy for Gastric Cancer With Peritoneal Metastasis | NCT03023436

Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric Cancer | NCT03229096

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