Published in PLoS One on August 24, 2010
Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells. PLoS One (2011) 1.22
Simian immunodeficiency virus-induced changes in T cell cytokine responses in cynomolgus macaques with latent Mycobacterium tuberculosis infection are associated with timing of reactivation. J Immunol (2011) 1.06
Immunodiagnosis of tuberculosis: a dynamic view of biomarker discovery. Clin Microbiol Rev (2011) 1.01
Identification of immunological biomarkers which may differentiate latent tuberculosis from exposure to environmental nontuberculous mycobacteria in children. Clin Vaccine Immunol (2013) 0.96
Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting. PLoS One (2013) 0.95
A simple method to quantitate IP-10 in dried blood and plasma spots. PLoS One (2012) 0.95
Evaluation of the diagnostic potential of IP-10 and IL-2 as biomarkers for the diagnosis of active and latent tuberculosis in a BCG-vaccinated population. PLoS One (2012) 0.94
Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area. PLoS One (2012) 0.94
Protection versus pathology in tuberculosis: recent insights. Curr Opin Immunol (2012) 0.92
Increased cytokines response in patients with tuberculosis complicated with chronic obstructive pulmonary disease. PLoS One (2013) 0.89
Reduced frequency of memory T cells and increased Th17 responses in patients with active tuberculosis. Clin Vaccine Immunol (2012) 0.87
Diverse cytokine profile from mesenteric lymph node cells of cull cows severely affected with Johne's disease. Clin Vaccine Immunol (2011) 0.87
Immune responses to ESAT-6 and CFP-10 by FASCIA and multiplex technology for diagnosis of M. tuberculosis infection; IP-10 is a promising marker. PLoS One (2012) 0.86
Differential cellular recognition pattern to M. tuberculosis targets defined by IFN-γ and IL-17 production in blood from TB + patients from Honduras as compared to health care workers: TB and immune responses in patients from Honduras. BMC Infect Dis (2013) 0.78
Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay. PLoS One (2013) 0.77
Role of QuantiFERON-TB Gold antigen-specific IL-1β in diagnosis of active tuberculosis. Med Microbiol Immunol (2014) 0.77
Gene expression profiling identifies candidate biomarkers for active and latent tuberculosis. BMC Bioinformatics (2016) 0.77
Broad adaptive immune responses to M. tuberculosis antigens precede TST conversion in tuberculosis exposed household contacts in a TB-endemic setting. PLoS One (2014) 0.76
Potential Role for Mycobacterium tuberculosis Specific IL-2 and IFN-γ Responses in Discriminating between Latent Infection and Active Disease after Long-Term Stimulation. PLoS One (2016) 0.75
Post-treatment change in Mycobacterium tuberculosis antigen-stimulated tumor necrosis factor-alpha release in patients with active tuberculosis. J Thorac Dis (2015) 0.75
Combined Expression of IFN-γ, IL-17, and IL-4 mRNA by Recall PBMCs Moderately Discriminates Active Tuberculosis from Latent Mycobacterium tuberculosis Infection in Patients with Miscellaneous Inflammatory Underlying Conditions. Front Immunol (2016) 0.75
A possible complementary tool for diagnosing tuberculosis: a feasibility test of immunohistochemical markers. Int J Clin Exp Pathol (2015) 0.75
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature (1999) 34.47
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med (2001) 18.25
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol (2007) 10.71
A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. N Engl J Med (1996) 7.66
Biomarkers for tuberculosis disease activity, cure, and relapse. Lancet Infect Dis (2009) 4.14
Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J Immunol (2008) 3.19
Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The Gambia. J Infect Dis (2008) 3.15
Diagnosis of tuberculosis based on the two specific antigens ESAT-6 and CFP10. Clin Diagn Lab Immunol (2000) 3.03
Cutting edge: IFN-gamma regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection. J Immunol (2006) 2.64
Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease. Eur J Immunol (2009) 2.16
Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin Vaccine Immunol (2006) 1.99
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. Clin Vaccine Immunol (2009) 1.67
Circulating profile of Th1 and Th2 cytokines in tuberculosis patients with different degrees of pulmonary involvement. FEMS Immunol Med Microbiol (1997) 1.58
Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: preliminary report. BMC Pulm Med (2009) 1.57
Mycobacterium africanum elicits an attenuated T cell response to early secreted antigenic target, 6 kDa, in patients with tuberculosis and their household contacts. J Infect Dis (2006) 1.56
Half-truths and selective memory: Interferon gamma, CD4(+) T cells and protective memory against tuberculosis. Tuberculosis (Edinb) (2007) 1.44
Induction of CD8 T cells against a novel epitope in TB10.4: correlation with mycobacterial virulence and the presence of a functional region of difference-1. J Immunol (2007) 1.42
Differential cytokine secretion and early treatment response in patients with pulmonary tuberculosis. Clin Exp Immunol (2009) 1.42
Use of spoligotyping and large sequence polymorphisms to study the population structure of the Mycobacterium tuberculosis complex in a cohort study of consecutive smear-positive tuberculosis cases in The Gambia. J Clin Microbiol (2009) 1.41
Role of QuantiFERON-TB gold, interferon gamma inducible protein-10 and tuberculin skin test in active tuberculosis diagnosis. PLoS One (2010) 1.34
Response to Rv2628 latency antigen associates with cured tuberculosis and remote infection. Eur Respir J (2009) 1.27
The quest for biomarkers in tuberculosis. Drug Discov Today (2009) 1.25
New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response. BMC Infect Dis (2009) 1.05
T Cells and Tuberculosis: Beyond Interferon-gamma. J Infect Dis (2008) 1.02
Ex vivo evaluation of PPD-specific IFN-gamma or IL-5 secreting cells in the peripheral blood and lungs of patients with tuberculosis. Int J Tuberc Lung Dis (2005) 0.91
Human host defense and cytokines in mycobacterial infectious diseases: interleukin-18 cannot compensate for genetic defects in the interleukin-12 system. Clin Infect Dis (2002) 0.81
T-cell and serological responses to Erp, an exported Mycobacterium tuberculosis protein, in tuberculosis patients and healthy individuals. BMC Infect Dis (2007) 0.81
Serum IL-18 levels in tuberculosis: comparison with pneumonia, lung cancer and healthy controls. Respirology (2005) 0.78
Variable host-pathogen compatibility in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 8.90
Treatment outcomes of patients with HIV and tuberculosis. Am J Respir Crit Care Med (2007) 3.32
Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The Gambia. J Infect Dis (2008) 3.15
Rifampin drug resistance tests for tuberculosis: challenging the gold standard. J Clin Microbiol (2013) 2.89
Large-scale evaluation of enzyme-linked immunospot assay and skin test for diagnosis of Mycobacterium tuberculosis infection against a gradient of exposure in The Gambia. Clin Infect Dis (2004) 2.62
A four-month gatifloxacin-containing regimen for treating tuberculosis. N Engl J Med (2014) 2.39
Longitudinal assessment of an ELISPOT test for Mycobacterium tuberculosis infection. PLoS Med (2007) 2.36
Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease. Eur J Immunol (2009) 2.16
Access to health care and mortality of children under 5 years of age in the Gambia: a case-control study. Bull World Health Organ (2009) 1.81
Incidence of tuberculosis and the predictive value of ELISPOT and Mantoux tests in Gambian case contacts. PLoS One (2008) 1.79
Quantitative T cell assay reflects infectious load of Mycobacterium tuberculosis in an endemic case contact model. Clin Infect Dis (2004) 1.71
Comparison of enzyme-linked immunospot assay and tuberculin skin test in healthy children exposed to Mycobacterium tuberculosis. Pediatrics (2006) 1.56
Mycobacterium africanum elicits an attenuated T cell response to early secreted antigenic target, 6 kDa, in patients with tuberculosis and their household contacts. J Infect Dis (2006) 1.56
Using ELISPOT to expose false positive skin test conversion in tuberculosis contacts. PLoS One (2007) 1.45
Polyfunctional CD4(+) and CD8(+) T cell responses to tuberculosis antigens in HIV-1-infected patients before and after anti-retroviral treatment. J Immunol (2010) 1.45
Infection with Helicobacter pylori is associated with protection against tuberculosis. PLoS One (2010) 1.45
Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. PLoS One (2010) 1.44
Factors associated with mortality in patients with drug-susceptible pulmonary tuberculosis. BMC Infect Dis (2011) 1.38
A telemedicine service for HIV/AIDS physicians working in developing countries. J Telemed Telecare (2010) 1.38
Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection. J Immunol (2006) 1.36
Risk factors for and clinical outcome of congenital cytomegalovirus infection in a peri-urban West-African birth cohort. PLoS One (2007) 1.33
Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa. PLoS One (2008) 1.25
Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design. Infect Immun (2004) 1.21
The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex. PLoS Negl Trop Dis (2012) 1.20
Mycobacterium africanum: a new opportunistic pathogen in HIV infection? AIDS (2005) 1.13
Commercial interferon gamma release assays compared to the tuberculin skin test for diagnosis of latent Mycobacterium tuberculosis infection in childhood contacts in the Gambia. Pediatr Infect Dis J (2010) 1.11
Impact, challenges, and future projections of vaccine trials in Africa. Am J Trop Med Hyg (2013) 1.10
Tuberculosis case-contact research in endemic tropical settings: design, conduct, and relevance to other infectious diseases. Lancet Infect Dis (2010) 1.08
High granulocyte/lymphocyte ratio and paucity of NKT cells defines TB disease in a TB-endemic setting. Tuberculosis (Edinb) (2009) 1.07
ESAT-6/CFP-10 fusion protein and peptides for optimal diagnosis of mycobacterium tuberculosis infection by ex vivo enzyme-linked immunospot assay in the Gambia. J Clin Microbiol (2005) 1.05
Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants. J Infect Dis (2006) 1.04
Identification of probable early-onset biomarkers for tuberculosis disease progression. PLoS One (2011) 1.00
Decay kinetics of an interferon gamma release assay with anti-tuberculosis therapy in newly diagnosed tuberculosis cases. PLoS One (2010) 1.00
Insertion sequence element single nucleotide polymorphism typing provides insights into the population structure and evolution of Mycobacterium ulcerans across Africa. Appl Environ Microbiol (2013) 0.98
Natural variation in immune responses to neonatal Mycobacterium bovis Bacillus Calmette-Guerin (BCG) Vaccination in a Cohort of Gambian infants. PLoS One (2008) 0.98
Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia. Trop Med Int Health (2009) 0.97
Interferon-γ ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: a clinical trial. Am J Respir Crit Care Med (2012) 0.96
Effects of cryopreservation on CD4+ CD25+ T cells of HIV-1 infected individuals. J Clin Lab Anal (2008) 0.95
Effect of a control project on clinical profiles and outcomes in buruli ulcer: a before/after study in Bas-Congo, Democratic Republic of Congo. PLoS Negl Trop Dis (2011) 0.95
Highly accurate diagnosis of pleural tuberculosis by immunological analysis of the pleural effusion. PLoS One (2012) 0.94
Impaired fitness of Mycobacterium africanum despite secretion of ESAT-6. J Infect Dis (2012) 0.92
The first phylogeographic population structure and analysis of transmission dynamics of M. africanum West African 1--combining molecular data from Benin, Nigeria and Sierra Leone. PLoS One (2013) 0.92
Delay in motor development of twins in Africa: a prospective cohort study. Twin Res (2003) 0.89
ESAT-6 and CFP-10 can be combined to reduce the cost of testing for Mycobacterium tuberculosis infection, but CFP-10 responses associate with active disease. Trans R Soc Trop Med Hyg (2007) 0.88
Immunogenic Mycobacterium africanum strains associated with ongoing transmission in The Gambia. Emerg Infect Dis (2013) 0.88
Burden of Mycobacterium ulcerans disease (Buruli ulcer) and the underreporting ratio in the territory of Songololo, Democratic Republic of Congo. PLoS Negl Trop Dis (2013) 0.88
Deciphering the growth behaviour of Mycobacterium africanum. PLoS Negl Trop Dis (2013) 0.86
Surprisingly high specificity of the PPD skin test for M. tuberculosis infection from recent exposure in The Gambia. PLoS One (2006) 0.86
AdvISER-PYRO: Amplicon Identification using SparsE Representation of PYROsequencing signal. Bioinformatics (2013) 0.85
Differences in T-cell responses between Mycobacterium tuberculosis and Mycobacterium africanum-infected patients. Eur J Immunol (2014) 0.83
Haematological and biochemical reference values of Gambian infants. Trop Med Int Health (2014) 0.83
Evaluation of the contribution of major T cell subsets to IFN-gamma production in TB infection by ELISPOT. Immunol Invest (2009) 0.82
Genetic variability of Mycobacterium tuberculosis complex in patients with no known risk factors for MDR-TB in the North-Eastern part of Lima, Peru. BMC Infect Dis (2013) 0.80
Supervised learning for the automated transcription of spacer classification from spoligotype films. BMC Bioinformatics (2009) 0.80
Pneumococcal antibody concentrations and carriage of pneumococci more than 3 years after infant immunization with a pneumococcal conjugate vaccine. PLoS One (2012) 0.79
Immune reconstitution inflammatory syndrome and the influence of T regulatory cells: a cohort study in The Gambia. PLoS One (2012) 0.79
Bacterial Isolates and Antibiotic Sensitivity among Gambian Children with Severe Acute Malnutrition. Int J Pediatr (2011) 0.78
Lessons in participant retention in the course of a randomized controlled clinical trial. BMC Res Notes (2014) 0.78
Skewing of the CD4(+) T-cell pool toward monofunctional antigen-specific responses in patients with immune reconstitution inflammatory syndrome in The Gambia. Clin Infect Dis (2013) 0.76
Catch them while you can! Am J Respir Crit Care Med (2008) 0.75
Correction: Whole Genome Comparisons Suggest Random Distribution of Mycobacterium ulcerans Genotypes in a Buruli Ulcer Endemic Region of Ghana. PLoS Negl Trop Dis (2015) 0.75