Published in J Biol Chem on September 07, 2010
MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma. PLoS One (2012) 1.42
The biology of head and neck cancer stem cells. Oral Oncol (2011) 1.25
Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma. FEBS J (2013) 1.12
A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review). Oncol Lett (2013) 1.09
Downregulation of miR-200a induces EMT phenotypes and CSC-like signatures through targeting the β-catenin pathway in hepatic oval cells. PLoS One (2013) 1.05
MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma. Mol Cancer (2013) 1.05
Cancer stem-like cells in Epstein-Barr virus-associated nasopharyngeal carcinoma. Chin J Cancer (2014) 1.02
Advanced research on vasculogenic mimicry in cancer. J Cell Mol Med (2015) 1.00
MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin. Int J Oncol (2011) 0.98
Regulation of breast cancer stem cell features. Contemp Oncol (Pozn) (2015) 0.97
Identification of a novel marine fish virus, Singapore grouper iridovirus-encoded microRNAs expressed in grouper cells by Solexa sequencing. PLoS One (2011) 0.95
KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelial-mesenchymal transition in epithelial cells. Mol Cell Biol (2013) 0.94
MicroRNAs in nasopharyngeal carcinoma. Chin J Cancer (2014) 0.94
miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. PLoS One (2013) 0.90
Aflatoxin B1 negatively regulates Wnt/β-catenin signaling pathway through activating miR-33a. PLoS One (2013) 0.89
CD133, Stem Cells, and Cancer Stem Cells: Myth or Reality? Curr Colorectal Cancer Rep (2011) 0.88
Neoplastic bone marrow niche: hematopoietic and mesenchymal stem cells. Cell J (2011) 0.86
Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas. Oncotarget (2015) 0.86
Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner. Mol Cell Biol (2013) 0.85
MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway. Oncotarget (2015) 0.84
MiR-205 promotes proliferation, migration and invasion of nasopharyngeal carcinoma cells by activation of AKT signalling. J Int Med Res (2016) 0.83
The role of microRNAs in nasopharyngeal carcinoma. Tumour Biol (2014) 0.82
Upregulated microRNA-92b regulates the differentiation and proliferation of EpCAM-positive fetal liver cells by targeting C/EBPß. PLoS One (2013) 0.82
A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma. Oncotarget (2016) 0.81
A humanized mouse model of HPV-associated pathology driven by E7 expression. PLoS One (2012) 0.80
Molecular characterization and clinical implications of spindle cells in nasopharyngeal carcinoma: a novel molecule-morphology model of tumor progression proposed. PLoS One (2013) 0.79
Targeting head and neck tumoral stem cells: From biological aspects to therapeutic perspectives. World J Stem Cells (2016) 0.79
Dysregulation of the PI3K/Akt signaling pathway affects cell cycle and apoptosis of side population cells in nasopharyngeal carcinoma. Oncol Lett (2015) 0.78
β-Catenin is important for cancer stem cell generation and tumorigenic activity in nasopharyngeal carcinoma. Acta Biochim Biophys Sin (Shanghai) (2016) 0.78
A novel miR-200b-3p/p38IP pair regulates monocyte/macrophage differentiation. Cell Discov (2016) 0.78
Arsenic-exposed Keratinocytes Exhibit Differential microRNAs Expression Profile; Potential Implication of miR-21, miR-200a and miR-141 in Melanoma Pathway. Clin Cancer Drugs (2016) 0.77
A pituitary homeobox 2 (Pitx2):microRNA-200a-3p:β-catenin pathway converts mesenchymal cells to amelogenin-expressing dental epithelial cells. J Biol Chem (2014) 0.76
Modeling nasopharyngeal carcinoma in three dimensions. Oncol Lett (2017) 0.75
MicroRNA-224 inhibits proliferation and migration of breast cancer cells by down-regulating Fizzled 5 expression. Oncotarget (2016) 0.75
MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma. BMC Cancer (2016) 0.75
MicroRNA-320a downregulation mediates human liver cancer cell proliferation through the Wnt/β-catenin signaling pathway. Oncol Lett (2016) 0.75
Loss of MYC and E-box3 binding contributes to defective MYC-mediated transcriptional suppression of human MC-let-7a-1~let-7d in glioblastoma. Oncotarget (2016) 0.75
Enhanced chemosensitivity by targeting Nanog in head and neck squamous cell carcinomas. Int J Mol Sci (2014) 0.75
Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice. PLoS One (2016) 0.75
Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17
Stem cells, cancer, and cancer stem cells. Nature (2001) 50.27
Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer (2006) 46.47
The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
Identification of human brain tumour initiating cells. Nature (2004) 38.87
Identification and expansion of human colon-cancer-initiating cells. Nature (2006) 24.44
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol (2008) 24.27
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell (2007) 22.89
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature (1994) 21.59
Wnt signalling in stem cells and cancer. Nature (2005) 19.26
Identification of pancreatic cancer stem cells. Cancer Res (2007) 18.36
Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell (2005) 15.06
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev (2008) 15.01
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep (2008) 10.71
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem (2008) 10.08
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell (2001) 10.02
Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat Rev Cancer (2005) 9.04
Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One (2008) 8.97
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol (2009) 8.63
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45
Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology (2007) 5.75
A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene (2006) 5.38
MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle (2008) 4.81
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60
Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res (2009) 4.36
Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells. Cancer Res (2009) 3.30
miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res (2009) 3.07
microRNAs and cancer: an overview. Cell Cycle (2008) 2.80
Epithelial-mesenchymal transition and cell cooperativity in metastasis. Cancer Res (2009) 2.68
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res (2007) 2.68
miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells. Stem Cells (2009) 2.64
Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma. Cancer Res (2007) 2.63
The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis. RNA Biol (2009) 2.56
Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens. Cancer Res (2007) 2.34
Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis. Head Neck (2008) 2.28
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer. Gynecol Oncol (2009) 2.26
A microRNA expression signature for cervical cancer prognosis. Cancer Res (2010) 2.14
CD133 as a marker for cancer stem cells: progresses and concerns. Stem Cells Dev (2009) 2.10
Epithelial-mesenchymal transition and the invasive potential of tumors. Trends Mol Med (2008) 2.07
Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway. Mol Cell Biol (2009) 2.06
Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition. Trends Cell Biol (2008) 1.82
The pluripotency regulator Oct4: a role in somatic stem cells? Cell Cycle (2008) 1.79
MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. Biochem Biophys Res Commun (2009) 1.66
miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion. Biochem Biophys Res Commun (2009) 1.61
The pluripotency homeobox gene NANOG is expressed in human germ cell tumors. Cancer (2005) 1.51
A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy. Cancer Lett (2009) 1.49
Identification of human aldehyde dehydrogenase 1 family member A1 as a novel CD8+ T-cell-defined tumor antigen in squamous cell carcinoma of the head and neck. Cancer Res (2007) 1.40
In vitro identification and characterization of CD133(pos) cancer stem-like cells in anaplastic thyroid carcinoma cell lines. PLoS One (2008) 1.27
Cell cycle-related kinase: a novel candidate oncogene in human glioblastoma. J Natl Cancer Inst (2007) 1.08
An RNAi screening platform to identify secretion machinery in mammalian cells. J Biotechnol (2007) 1.04
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet (2011) 6.98
Discovery of tissue-specific exons using comprehensive human exon microarrays. Genome Biol (2007) 5.53
Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing. Nature (2003) 5.04
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature (2012) 4.37
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer (2009) 3.90
A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle. Mol Cell (2003) 3.88
p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev (2005) 3.88
Clinical application of massively parallel sequencing-based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11,105 pregnancies with mixed risk factors. Prenat Diagn (2012) 3.54
Single-layer MoS2 phototransistors. ACS Nano (2011) 3.43
Probe selection for high-density oligonucleotide arrays. Proc Natl Acad Sci U S A (2003) 3.31
Gene structure-based splice variant deconvolution using a microarray platform. Bioinformatics (2003) 2.97
The main auxin biosynthesis pathway in Arabidopsis. Proc Natl Acad Sci U S A (2011) 2.87
Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris. Genome Res (2005) 2.65
Unexplained subdural hematoma in young children: is it always child abuse? Pediatr Int (2002) 2.57
The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut (2011) 2.33
Ultra-early (within 24 hours) aneurysm treatment after subarachnoid hemorrhage. World Neurosurg (2011) 2.22
Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer. Clin Cancer Res (2011) 2.08
Heterosis. Plant Cell (2010) 2.06
High-dose simvastatin for aneurysmal subarachnoid hemorrhage: a multicenter, randomized, controlled, double-blind clinical trial protocol. Neurosurgery (2013) 2.02
Locally injection of cell sheet fragments enhances new bone formation in mandibular distraction osteogenesis: a rabbit model. J Orthop Res (2013) 1.95
Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling. Hepatology (2011) 1.93
Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87. Cancer Lett (2008) 1.93
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem (2005) 1.92
ANOSVA: a statistical method for detecting splice variation from expression data. Bioinformatics (2005) 1.88
From a single-band metal to a high-temperature superconductor via two thermal phase transitions. Science (2011) 1.87
EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies. Gut (2011) 1.87
microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. Brain Res (2009) 1.76
N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int J Cancer (2003) 1.75
Fabrication of single- and multilayer MoS2 film-based field-effect transistors for sensing NO at room temperature. Small (2011) 1.69
MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. Biochem Biophys Res Commun (2009) 1.66
Ex vivo delivered stromal cell-derived factor-1alpha promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium. J Mol Cell Cardiol (2007) 1.61
miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion. Biochem Biophys Res Commun (2009) 1.61
Tea and cancer prevention: molecular mechanisms and human relevance. Toxicol Appl Pharmacol (2006) 1.61
Single-layer semiconducting nanosheets: high-yield preparation and device fabrication. Angew Chem Int Ed Engl (2011) 1.60
MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling. RNA Biol (2011) 1.53
MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix. Mol Biol Cell (2011) 1.46
Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells. J Biol Chem (2012) 1.43
Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin. Hepatology (2007) 1.40
Biological consequences of dosage dependent gene regulatory systems. Biochim Biophys Acta (2007) 1.39
c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2. J Biol Chem (2013) 1.37
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism. Cell Res (2010) 1.36
Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease. Mol Cell (2011) 1.36
Simple sequence repeat-based consensus linkage map of Bombyx mori. Proc Natl Acad Sci U S A (2005) 1.35
Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A). Int J Cancer (2010) 1.34
Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair. Cardiovasc Res (2007) 1.34
Specific and modular binding code for cytosine recognition in Pumilio/FBF (PUF) RNA-binding domains. J Biol Chem (2011) 1.32
Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma. Hepatology (2009) 1.32
HOXB7 as a prognostic factor and mediator of colorectal cancer progression. Clin Cancer Res (2011) 1.31
1-[2,2-Bis(1,3-benzimidazol-1-ylmeth-yl)-3-bromo-prop-yl]-1,3-benzimidazole. Acta Crystallogr Sect E Struct Rep Online (2011) 1.30
The genome of the hydatid tapeworm Echinococcus granulosus. Nat Genet (2013) 1.29
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice. Cancer Prev Res (Phila) (2009) 1.27
p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart. Circulation (2005) 1.26
miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1. Int J Oncol (2012) 1.26
High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients. Mol Med (2010) 1.26
Serum biomarkers of hepatitis B virus infected liver inflammation: a proteomic study. Proteomics (2003) 1.26
Inhibition of carcinogenesis by tea constituents. Semin Cancer Biol (2007) 1.25
Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAPKerk and MAPKp38. Diabetes (2003) 1.24
Dithienosilole- and dibenzosilole-thiophene copolymers as semiconductors for organic thin-film transistors. J Am Chem Soc (2006) 1.23
Curcumin induces the differentiation of myeloid-derived suppressor cells and inhibits their interaction with cancer cells and related tumor growth. Cancer Prev Res (Phila) (2011) 1.21
A new and sensitive method for the quantification of HBV cccDNA by real-time PCR. Biochem Biophys Res Commun (2002) 1.20
MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF. Cell Cycle (2012) 1.20
Overexpression of eIF5A-2 is an adverse prognostic marker of survival in stage I non-small cell lung cancer patients. Int J Cancer (2011) 1.19
How useful is glucose detection in diagnosing cerebrospinal fluid leak? The rational use of CT and Beta-2 transferrin assay in detection of cerebrospinal fluid fistula. Asian J Surg (2004) 1.19
Mitochondrial and energy metabolism-related properties as novel indicators of lung cancer stem cells. Int J Cancer (2011) 1.18
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody. Drug Metab Dispos (2006) 1.18
Preparation of novel 3D graphene networks for supercapacitor applications. Small (2011) 1.17
Possible mechanisms of the cancer-preventive activities of green tea. Mol Nutr Food Res (2006) 1.17
Molecular targets for the cancer preventive activity of tea polyphenols. Mol Carcinog (2006) 1.17
Epidemiological dynamics and phylogeography of influenza virus in southern China. J Infect Dis (2012) 1.16
High-performance transparent inorganic-organic hybrid thin-film n-type transistors. Nat Mater (2006) 1.16
Enterovirus 71 disrupts interferon signaling by reducing the level of interferon receptor 1. J Virol (2012) 1.15
Diabetes gene therapy: potential and challenges. Curr Gene Ther (2003) 1.15
Primate-specific miR-663 functions as a tumor suppressor by targeting PIK3CD and predicts the prognosis of human glioblastoma. Clin Cancer Res (2014) 1.15
Unraveling the genetic basis of hybrid vigor. Proc Natl Acad Sci U S A (2006) 1.11
Computational identification and characterization of primate-specific microRNAs in human genome. Comput Biol Chem (2010) 1.11