Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia.

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Published in Front Neuroanat on September 14, 2010

Authors

Pedro Barroso-Chinea1, Erwan Bezard

Author Affiliations

1: Centre National de la Recherche Scientifique UMR 5227, Bordeaux Institute of Neuroscience, Université Victor-Segalen Bordeaux 2 Bordeaux, France.

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Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci (1986) 18.17

The functional anatomy of basal ganglia disorders. Trends Neurosci (1989) 12.28

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Primate models of movement disorders of basal ganglia origin. Trends Neurosci (1990) 7.63

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature (2010) 7.35

The basal ganglia: focused selection and inhibition of competing motor programs. Prog Neurobiol (1996) 7.24

A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. N Engl J Med (2000) 6.21

Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum. J Neurosci (2000) 6.02

Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. Prog Brain Res (1990) 5.79

Non-motor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol (2006) 5.40

Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res Brain Res Rev (1995) 5.23

Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci (2006) 4.98

Circuits and circuit disorders of the basal ganglia. Arch Neurol (2007) 3.97

Different time courses of learning-related activity in the prefrontal cortex and striatum. Nature (2005) 3.84

Central mechanisms of motor skill learning. Curr Opin Neurobiol (2002) 3.84

The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism. J Neurophysiol (1994) 3.42

Functional significance of the cortico-subthalamo-pallidal 'hyperdirect' pathway. Neurosci Res (2002) 3.34

Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science (2001) 3.18

Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov Disord (2001) 2.89

Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. Trends Neurosci (1989) 2.83

Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions. J Neurochem (1991) 2.66

Cortical inputs and GABA interneurons imbalance projection neurons in the striatum of parkinsonian rats. J Neurosci (2006) 2.64

Network modulation in the treatment of Parkinson's disease. Brain (2006) 2.52

Changes in network activity with the progression of Parkinson's disease. Brain (2007) 2.46

Functional and pathophysiological models of the basal ganglia. Curr Opin Neurobiol (1996) 2.45

Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages). J Neurol (2002) 2.37

Efferent connections of the substantia nigra and ventral tegmental area in the rat. Brain Res (1979) 2.36

Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms. Lancet Neurol (2009) 2.28

Histochemical changes in cytochrome oxidase of cortical barrels after vibrissal removal in neonatal and adult mice. Proc Natl Acad Sci U S A (1980) 2.16

Metabolic brain networks in neurodegenerative disorders: a functional imaging approach. Trends Neurosci (2009) 2.16

L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. Eur J Neurosci (1998) 2.10

D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum. J Comp Neurol (1995) 2.01

Projection subtypes of rat neostriatal matrix cells revealed by intracellular injection of biocytin. J Neurosci (1990) 1.96

Regulation of gamma-aminobutyric acid synthesis in the brain. J Neurochem (1993) 1.86

Network modulation by the subthalamic nucleus in the treatment of Parkinson's disease. Neuroimage (2006) 1.84

L-Dopa (L-3,4-dihydroxyphenylanine)--its clinical effects in parkinsonism. Trans Am Neurol Assoc (1968) 1.76

Molecular effects of dopamine on striatal-projection pathways. Trends Neurosci (2000) 1.73

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. J Neurosci (2001) 1.72

The cortico-striate projection in the monkey. Brain (1970) 1.72

Molecular mechanisms of L-DOPA-induced dyskinesia. Nat Rev Neurosci (2008) 1.71

Evidence for differential cortical input to direct pathway versus indirect pathway striatal projection neurons in rats. J Neurosci (2004) 1.67

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience (1989) 1.64

Neuronal activity in the basal ganglia in patients with generalized dystonia and hemiballismus. Ann Neurol (1999) 1.64

Macro-architecture of basal ganglia loops with the cerebral cortex: use of rabies virus to reveal multisynaptic circuits. Prog Brain Res (2004) 1.58

Pathophysiology of levodopa-induced dyskinesia: potential for new therapies. Nat Rev Neurosci (2001) 1.57

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L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function. Neurobiol Dis (2002) 1.54

Evidence of a breakdown of corticostriatal connections in Parkinson's disease. Neuroscience (2005) 1.51

Metabolic correlates of levodopa response in Parkinson's disease. Neurology (2001) 1.50

Plasticity of synapses in the rat neostriatum after unilateral lesion of the nigrostriatal dopaminergic pathway. J Neurosci (1998) 1.47

The structure of the caudate nucleus of the cat: light and electron microscopy. Philos Trans R Soc Lond B Biol Sci (1971) 1.45

FDG PET in the differential diagnosis of parkinsonian disorders. Neuroimage (2005) 1.40

Efferent projections of the subthalamic nucleus in the rat: light and electron microscopic analysis with the PHA-L method. J Comp Neurol (1987) 1.39

Corticosubthalamic input zones from forelimb representations of the dorsal and ventral divisions of the premotor cortex in the macaque monkey: comparison with the input zones from the primary motor cortex and the supplementary motor area. Neurosci Lett (1997) 1.36

Organization of the basal ganglia: the importance of axonal collateralization. Trends Neurosci (2000) 1.31

Monosynaptic inputs to caudate neurons identified by intracellular injection of horseradish peroxidase. Brain Res (1976) 1.28

Learning networks in health and Parkinson's disease: reproducibility and treatment effects. Hum Brain Mapp (2003) 1.23

Pathophysiology of levodopa-induced dyskinesias in Parkinson's disease: problems with the current model. Ann Neurol (2000) 1.18

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Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys. Exp Neurol (2008) 1.14

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Efferent connections of the centromedian and parafascicular thalamic nuclei in the squirrel monkey: a PHA-L study of subcortical projections. J Comp Neurol (1992) 1.13

The striatofugal fiber system in primates: a reevaluation of its organization based on single-axon tracing studies. Proc Natl Acad Sci U S A (2005) 1.13

Regulatory properties of brain glutamate decarboxylase (GAD): the apoenzyme of GAD is present principally as the smaller of two molecular forms of GAD in brain. J Neurosci (1991) 1.13

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Excitatory amino acids in synaptic excitation of rat striatal neurones in vitro. J Physiol (1988) 1.06

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Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Res (1991) 0.96

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Organization of efferent projections from the internal segment of globus pallidus in primate as revealed by fluorescence retrograde labeling method. Brain Res (1982) 0.91

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Preproenkephalin and preprotachykinin messenger RNA expression in normal human basal ganglia and in Parkinson's disease. Neuroscience (1995) 0.90

Nigral and pallidal inputs to functionally segregated thalamostriatal neurons in the centromedian/parafascicular intralaminar nuclear complex in monkey. J Comp Neurol (2002) 0.90

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